JP2024044470A - Collection kit and collection method - Google Patents

Abstract

To provide a collection kit and a collection method for efficient culture testing of a blood product.SOLUTION: The present invention comprises: an inflow tube 12 to which a medical bag is connected; a storage section 14 having a first storage chamber 31 and a second storage chamber 32 capable of storing an object to be collected; an air vent 16 for discharging air from the storage section 14; and an adapter 20 that can be connected to culture bottles B1 and B2. The inflow tube 12 is connected to the first storage chamber 31. The storage section 14 has an openable/closable partition structure 22 that partitions the first storage chamber 31 and the second storage chamber 32. In the collection method, the object to be collected is collected into two culture bottles B1 and B2 using a collection kit 10.SELECTED DRAWING: Figure 1

Description

The present invention relates to a collection kit and collection method for transferring a sample to a culture bottle.

Blood products include red blood cell products, plasma products, platelet products, and whole blood products. Blood products that contain the components required by patients are used for transfusions. Blood products are stored and transported in medical bags. To ensure safety, small samples of blood products may be taken and cultured. Culture tests detect the presence or absence of pathogens by collecting the sample in a culture bottle and placing the culture bottle in an environment favorable for bacterial growth.

For example, testing of platelet preparations is performed in the following procedure. A small-capacity collection bag is connected to a medical bag (hereafter referred to as a platelet bag) that contains the platelet preparation. Then, a portion of the platelet preparation in the platelet bag is transferred to the collection bag. Next, the collection bag is disconnected from the platelet bag.

The collection bag is then transferred to a clean bench. In the clean bench, the platelet product is injected from the collection bag into a blood culture bottle. Prior to injection, the tube of the collection bag is connected to the tube extending from the sample collection tube. Using the graduations on the sample collection tube as a guide, a specified amount of the platelet product is transferred from the collection bag to the sample collection tube.

Then, while visually checking the scale on the sample collection tube, the operator operates the valve of the sample collection tube to transfer a specified amount of the platelet preparation from the sample collection tube to a blood culture bottle. In the culture test, anaerobic culture and aerobic culture are performed. Therefore, the platelet preparation is dispensed into a culture bottle to be used for anaerobic culture and a culture bottle to be used for aerobic culture. Then, each culture bottle is set in a culture device and used for culture testing for a specified period of time.

For example, Patent Document 1 discloses a collection kit for collecting samples from medical bags.

US Patent No. 8777921

When performing culture tests for blood products in large quantities, it is necessary to improve the work efficiency of culture tests. In the conventional testing procedure, the process from dispensing the blood product from the blood product bag to the culture bottle requires work to attach and detach the collection bag and sample collection tube, which is complicated. Since it is necessary to manually measure and collect blood products by aligning them with scale lines, the work is not easy and measurement errors are likely to occur.

The present invention aims to solve the above-mentioned problems.

(1) A first aspect of the present invention includes an inflow tube to which a medical bag containing an object to be collected is connected, and a first storage chamber connected downstream of the inflow tube and capable of accommodating the object to be collected. and a storage part having a second storage chamber, an air vent connected to the upper part of the second storage chamber and discharging air from the storage part, and an adapter connected to the first storage chamber and connectable to a culture bottle. , the inflow tube is connected to the first storage chamber, and the storage section has an openable and closable partition structure that partitions the first storage chamber and the second storage chamber. .

In the work of collecting a collection target into a culture bottle using a collection kit, the number of times of joining and separating tubes can be minimized, resulting in excellent work efficiency. Since the storage section is partitioned into a first storage chamber and a second storage chamber by a partition wall structure, the object to be collected to be collected into the first culture bottle can be stored in the first storage chamber, and the object to be collected in the second culture bottle can be stored in the first storage chamber. The object to be collected to be collected into the culture bottle can be stored in the second storage chamber. This eliminates the need to manually measure and collect the object to be collected along the scale lines, making the work easier and reducing measurement errors. Therefore, according to the collection kit, it is possible to suppress variations in the amount of the object to be collected introduced into the first culture bottle and the second culture bottle.

(2) In the collection kit described in item (1) above, the partition structure includes a partition main body in which a communication passage is formed, and a slide member that is movable relative to the partition main body and can open and close the communication passage. It may have.

With this configuration, a partition wall structure that can be opened and closed can be constructed with a simple structure.

(3) In the collection kit described in item (2) above, a hydrophilic filter may be disposed adjacent to the partition structure, and when the partition structure is in an open state, the first storage chamber and the second storage chamber may be in communication with each other via the communication passage and the hydrophilic filter.

When transferring the collection target from the first storage chamber to the second culture bottle, the hydrophilic filter prevents air from flowing into the first storage chamber from the second storage chamber. Therefore, it is possible to prevent air from entering the second culture bottle. Therefore, the second culture bottle can be used as a culture bottle for anaerobic bacteria.

(4) In the collection kit described in item (2) or (3) above, the storage section has a cylindrical first cylinder having the first storage chamber and a cylindrical second cylinder having the second storage chamber, the partition body is provided on the first cylinder, the slide member is provided on the second cylinder, the first cylinder and the second cylinder are liquid-tightly connected to be rotatable relative to each other around the axis of the storage section, and the partition structure may open and close with the relative rotation between the first cylinder and the second cylinder.

The user grasps the first cylinder with one hand and the second cylinder with the other hand, and rotates the first cylinder and the second cylinder relative to each other, thereby opening and closing the partition structure. It can be done easily.

(5) A second aspect of the present invention is a collection method in which a collection target is collected into two culture bottles using a collection kit, wherein the collection kit is connected to a medical bag containing the collection target. an inflow tube connected to the downstream side of the inflow tube and having a first storage chamber and a second storage chamber capable of accommodating the object to be collected; An air vent for discharging air from the storage section; an adapter connected to the first storage chamber and connectable to a culture bottle; the inflow tube is connected to the first storage chamber; It has an openable/closable partition structure that partitions the first storage chamber and the second storage chamber, and the collection method includes a joining step of joining the medical bag to the inflow tube, and a step of joining the partition structure in an open state. an introduction step of introducing the object to be collected into the first storage chamber and the second storage chamber through the inflow tube while the partition wall structure is in a closed state; and a step of switching the partition structure into a closed state. a first transfer step of connecting a first culture bottle to the adapter while keeping the adapter in place, and transferring the object to be collected from the first storage chamber to the first culture bottle; This collection method includes a second transfer step of connecting the bottles and transferring the object to be collected to the second culture bottle.

According to the present invention, in the operation of collecting a collection target into a culture bottle using a collection kit, the number of times tubes are joined and separated can be minimized, resulting in excellent work efficiency. Since the storage section is divided into a first storage chamber and a second storage chamber by a partition structure, the collection target to be collected into the first culture bottle can be stored in the first storage chamber, and the collection target to be collected into the second culture bottle can be stored in the second storage chamber. This eliminates the need to measure the collection target by eye according to the scale lines, making the operation easier and reducing measurement errors. Therefore, the collection kit can suppress variation in the amount of collection target introduced into the first culture bottle and the second culture bottle.

FIG. 1 is an overall schematic diagram of a collection kit according to a first embodiment of the present invention. FIG. 2 is an exploded perspective view of the partition structure. FIG. 3 is a first diagram illustrating a method of using the collection kit according to the first embodiment of the present invention. FIG. 4 is a second diagram illustrating a method of using the collection kit according to the first embodiment of the present invention. FIG. 5 is a third diagram illustrating how to use the collection kit according to the first embodiment of the present invention. FIG. 6 is a fourth diagram illustrating a method of using the collection kit according to the first embodiment of the present invention. FIG. 7 is a fifth diagram illustrating how to use the collection kit according to the first embodiment of the present invention. FIG. 8 is a perspective view of a partition structure according to a second configuration example. FIG. 9 is a cross-sectional view of a partition structure according to the third configuration example. FIG. 10 is an overall schematic diagram of a collection kit according to a second embodiment of the present invention. FIG. 11 is a cross-sectional view taken along line XI-XI in FIG. 10.

The collection kit 10 according to the first embodiment shown in FIG. 1 is used to transfer blood products, which are objects to be collected, to culture bottles B1 and B2. The collection kit 10 is used, for example, in a culture test for confirming the safety of blood products at a business facility such as a blood center that manufactures blood products. In the culture test, anaerobic bacteria culture and aerobic bacteria culture are tested. Therefore, a total of two culture bottles, one for aerobic culture and one for anaerobic culture, are used in the culture test. Among the two culture bottles B1 and B2, one culture bottle is used for the test as a culture bottle for aerobic bacteria, and the other culture bottle is used for the test as a culture bottle for anaerobic bacteria.

In the following, in the first embodiment (and the second embodiment described later), an example will be described in which a platelet preparation is used as the blood product, but the blood product collected by the collection kit 10 may be a red blood cell preparation, a plasma preparation, or a whole blood product.

The collection kit 10 comprises an inflow tube 12, a storage section 14, an air vent 16, and an adapter 20. In the collection kit 10, the direction in which the air vent 16 is located is referred to as the upper side or upward, and the direction in which the adapter 20 is located is referred to as the lower side or downward, based on the arrangement state during use.

The inflow tube 12 is a translucent medical tube made of a thermoplastic resin such as polyvinyl chloride resin. The inflow tube 12 can be connected to or disconnected from other medical tubes without exposing the inside to the outside air, for example, by a sterile joining device or a tube sealer. The inflow tube 12 has a first end 121 on the upstream side and a second end 122 on the downstream side. The first end 121 is welded and sealed in the initial state. The second end 122 is connected to the storage section 14.

The storage section 14 is formed of a hard material. Examples of materials that can be used to form the storage section 14 include hard resin materials such as polypropylene, polyethylene, cyclic polyolefin, and polyacetal resin. The storage section 14 has a first storage chamber 31 and a second storage chamber 32 that can store the object to be collected. The storage section 14 has a capacity of, for example, about 16 to 20 mL. The first storage chamber 31 has a capacity for storing a predetermined amount (for example, about 8 to 10 mL) of platelet preparation. The second storage chamber 32 has a capacity for storing a predetermined amount (for example, about 8 to 10 mL) of platelet preparation. The first storage chamber 31 and the second storage chamber 32 have approximately the same capacity.

The storage section 14 is formed in a substantially cylindrical shape. The first storage chamber 31 and the second storage chamber 32 are arranged in series along the axial direction (up-down direction) of the storage section 14. The storage section 14 has an openable partition structure 22 that separates the first storage chamber 31 and the second storage chamber 32. The partition structure 22 can be switched between an open state that connects the first storage chamber 31 and the second storage chamber 32, and a closed state that blocks communication between the first storage chamber 31 and the second storage chamber 32. The partition structure 22 has a partition body 24 in which a communication passage 241 is formed, and a slide member 26 that is displaceable relative to the partition body 24 and can open and close the communication passage 241.

As shown in FIG. 2, the partition body 24 is formed in a disk shape. The partition body 24 has a plurality of communication passages 241 penetrating the partition body 24 in the thickness direction, and a plurality of wall portions 242 (non-communicating portions) formed between the plurality of communication passages 241. The plurality of communication passages 241 are arranged at intervals from one another in the circumferential direction centered on the axis line AX of the storage section 14. The plurality of wall portions 242 are arranged at intervals from one another in the circumferential direction centered on the axis line AX of the storage section 14.

The slide member 26 is rotatable relative to the partition main body 24 about the axis AX of the accommodating portion 14, and overlaps the upper surface of the partition main body 24. The slide member 26 is formed into a disk shape. It has a plurality of holes 261 passing through the slide member 26 in the thickness direction and a plurality of closing portions 262 formed between the plurality of holes 261. The plurality of holes 261 are arranged at intervals in a circumferential direction centered on the axis AX of the accommodating portion 14 . The plurality of closing parts 262 are arranged at intervals from each other in the circumferential direction centered on the axis AX of the accommodating part 14. The number of holes 261 in the slide member 26 is the same as the number of communication passages 241 in the partition main body 24. Note that the partition main body 24 may be provided with a single communication path 241 and the slide member 26 may be provided with a single hole 261.

In FIG. 1, the relative positions of the communication passage 241 and the hole 261 change depending on the relative position of the slide member 26 with respect to the partition body 24. The communication passage 241 of the partition body 24 and the hole 261 of the slide member 26 overlap and communicate with each other, thereby communicating the first storage chamber 31 and the second storage chamber 32. In FIG. 1, the partition structure 22 is in an open state. The relative position of the slide member 26 with respect to the partition body 24 changes, and the communication passage 241 of the partition body 24 is blocked by the blocking portion 262 of the slide member 26, blocking communication between the first storage chamber 31 and the second storage chamber 32.

A hydrophilic filter 30 is arranged inside the housing section 14 . The hydrophilic filter 30 has a property of making it difficult for gas to pass through when it gets wet. Hydrophilic filter 30 is located adjacent to partition structure 22 . Specifically, the hydrophilic filter 30 overlaps the partition main body 24 so as to cover the communication path 241 on the side opposite to the slide member 26 with respect to the partition main body 24 . In other embodiments, the hydrophilic filter 30 may be placed in the communication path 241. The hydrophilic filter 30 may overlap the slide member 26 so as to cover the hole 261 on the side opposite to the partition main body 24 with respect to the slide member 26 .

The accommodating portion 14 includes a cylindrical first body 141 in which a first accommodating chamber 31 is formed, and a cylindrical second cylindrical body 142 in which a second accommodating chamber 32 is formed. The partition main body 24 is fixed to the upper end of the first cylindrical body 141 . A boss portion 143 protrudes from the outer peripheral portion of the first cylindrical body 141 . The second end 122 of the inflow tube 12 is connected to the boss 143 . Inflow tube 12 extends upward from boss portion 143 . The inflow tube 12 communicates with the first storage chamber 31 via a flow path 144 formed in the boss portion 143 . The flow path 144 opens at the lower part of the first storage chamber 31 . The slide member 26 is fixed to the second cylinder 142 at a position slightly above the lower end of the second cylinder 142 .

The first cylindrical body 141 and the second cylindrical body 142 are fluid-tightly connected to each other so as to be relatively rotatable about the axis AX of the accommodating portion 14 . The upper end of the first cylinder 141 is inserted into the lower end of the second cylinder 142. A liquid-tight sealing packing 33 is arranged between the first cylinder 141 and the second cylinder 142. Note that a configuration may be adopted in which the lower end of the second cylindrical body 142 is inserted into the upper end of the first cylindrical body 141.

The air vent 16 is connected to the upper part of the housing section 14 . The air vent 16 exhausts air from the storage section 14 when the object to be collected is introduced into the storage section 14 via the inflow tube 12 . The air vent 16 includes a ventilation cylinder 161 that constitutes a vent body, and a sterile filter 162 arranged inside the ventilation cylinder 161. Note that the air vent 16 may be configured as a one-way valve that allows air to flow out from the housing section 14 to the outside and prevents air from flowing into the housing section 14 from the outside.

The adapter 20 is connected to the lower part of the housing section 14 . The adapter 20 communicates with the first storage chamber 31 and can be connected to the culture bottles B1 and B2. The adapter 20 includes a storage tube 34 capable of accommodating the heads of culture bottles B1 and B2, a transfer tube 38 having a tubular needle portion 36 arranged inside the storage tube 34, and a rubber cover 40 that covers the needle portion 36. Equipped with. The housing cylinder 34 has a lid 341 that can be opened and closed. The needle part 36 can puncture a rubber stopper attached to the head of the culture bottle B1. When the needle portion 36 of the adapter 20 penetrates the rubber stopper of the culture bottle B1, the culture bottle B1 and the first storage chamber 31 communicate with each other. When the needle part 36 is inserted into the rubber stopper of the culture bottle B1, the rubber cover 40 is pushed toward the proximal end, and the needle part 36 passes through the rubber cover 40. When the needle part 36 is removed from the rubber stopper of the culture bottle B1, the rubber cover 40 is expanded by its elastic restoring force and covers the needle part 36 again.

The collection kit 10 configured as described above is used as follows. In this embodiment, a collection method is described in which the collection kit 10 is used to dispense a platelet preparation into two culture bottles B1 and B2.

As shown in FIG. 3, the platelet bag 50 is joined to the collection kit 10 (joining step). The platelet bag 50 is a medical bag containing a platelet preparation. The platelet bag 50 has a tube 52 for connection. Tube 52 is joined to inflow tube 12 . The tube 52 is joined to the inflow tube 12 using a sterile joining device without coming into contact with the outside air.

Next, as shown in FIG. 4, the platelet preparation is introduced into the storage section 14 (introduction process). In the introduction process, the partition structure 22 is switched to the open state, and the platelet bag 50 is positioned above the storage section 14. The platelet preparation flows out of the platelet bag 50 by gravity, and is stored in the storage section 14 via the tube 52 and the inflow tube 12.

The platelet preparation is stored in the first storage chamber 31 and the second storage chamber 32. In this case, the platelet preparation is stored from the bottom of the first storage chamber 31, and the liquid level of the platelet preparation rises within the first storage chamber 31. As the liquid level of the platelet preparation within the storage section 14 rises, the air within the storage section 14 is pushed out by the platelet preparation and is discharged to the outside of the storage section 14 via the air vent 16 . The level of platelet product rises above the hydrophilic filter 30 and septum structure 22.

In the process of rising the liquid level of the platelet preparation, the platelet preparation flows from the first storage chamber 31 to the second storage chamber 32 via the communication path 241 and hole 261 of the partition structure 22 . When the platelet preparation reaches the upper end of the second storage chamber 32, the first storage chamber 31 and the second storage chamber 32 are filled with the platelet preparation. This completes the introduction of the platelet preparation into the storage section 14. As a result, the first storage chamber 31 and the second storage chamber 32 each contain a predetermined amount (for example, about 8 to 10 mL) of platelet preparation. When the introduction of the platelet preparation into the storage part 14 is completed, the partition wall structure 22 is switched to the closed state by relatively rotating the first cylinder 141 and the second cylinder 142.

The platelet bag 50 is then separated from the inflow tube 12 by a tube sealer (high frequency sealer or ultrasonic sealer) or the like. The tube sealer separates the inflow tube 12 from the tube 52 of the platelet bag 50 and simultaneously seals the first end 121 of the inflow tube 12 by welding. The inflow tube 12 is separated from the tube 52 without exposing the internal flow path to the outside air.

The removed platelet bag 50 is stored until the culture test is completed, and then is made available for use. Meanwhile, the collection kit 10 filled with the platelet preparation is carried into a clean bench. Next, the user performs an operation to transfer the platelet preparation from the collection kit 10 to the two culture bottles B1 and B2.

As shown in FIG. 5, the platelet preparation is transferred from the storage unit 14 to the first culture bottle B1 (first transfer step). Culture bottle B1 is a culture bottle for aerobic bacteria. In the first transfer step, the culture bottle B1 is connected to the adapter 20. As the culture bottle B1 is connected to the adapter 20, the needle portion 36 of the adapter 20 penetrates the rubber stopper of the culture bottle B1. The platelet preparation in the first storage chamber 31 is sucked out by the negative pressure of the culture bottle B1, and a predetermined amount (for example, about 8 to 10 mL) of the platelet preparation is transferred to the culture bottle B1 via the transfer pipe 38 having the needle part 36. be introduced. When the platelet preparation is introduced into the culture bottle B1, a small amount of air that was present in the flow path within the transfer tube 38 including the needle portion 36 is also introduced into the culture bottle B1. Therefore, a small amount of air is mixed into the culture bottle B1.

Next, the culture bottle B1 is removed from the adapter 20. The partition structure 22 is in a closed state, and the first storage chamber 31 and the second storage chamber 32 are liquid-tightly separated by the partition structure 22, so the platelet preparation remains in the second storage chamber 32. Since the platelet preparation has been discharged from the first storage chamber 31, negative pressure is created inside the first storage chamber 31.

Next, as shown in FIG. 6, the object to be collected is moved from the first storage chamber 31 to the second storage chamber 32 (moving step). Specifically, by relatively rotating the first cylindrical body 141 and the second cylindrical body 142, the partition wall structure 22 is switched from the closed state to the open state. Since the first storage chamber 31 is under negative pressure, the platelet preparation moves from the second storage chamber 32 to the first storage chamber 31 when the partition wall structure 22 is opened. The platelet preparation moves from the second storage chamber 32 to the first storage chamber 31 via the hole 261 of the partition structure 22 and the communication path 241. Note that after the platelet preparation is moved from the second storage chamber 32 to the first storage chamber 31, the partition structure 22 may remain in the open state or may be switched to the closed state.

Next, as shown in FIG. 7, the platelet preparation is transferred to the second culture bottle B2 (second transfer step). The culture bottle B2 is a culture bottle for anaerobic bacteria. In the second transfer step, the culture bottle B2 is connected to the adapter 20. With this connection, a predetermined amount (for example, about 8 to 10 mL) of the platelet preparation is introduced into the culture bottle B2. When the platelet preparation is collected in the second culture bottle B2, the hydrophilic filter 30 is already wet with the platelet preparation. The hydrophilic filter 30 has a property of making it difficult for gas to pass through when it is wet. Since the hydrophilic filter 30 is disposed between the first storage chamber 31 and the second storage chamber 32, air does not flow from the second storage chamber 32 to the first storage chamber 31 regardless of the open/closed state of the partition structure 22. Therefore, the intrusion of air into the culture bottle B2 is prevented. After the predetermined amount of the platelet preparation is introduced into the culture bottle B2, the culture bottle B2 is removed from the adapter 20.

The above steps complete the collection of platelet preparations using the collection kit 10.

The first embodiment has the following effects.

In the work of collecting a collection target into the culture bottles B1 and B2 using the collection kit 10, the number of times of joining and separating tubes can be minimized, resulting in excellent work efficiency. Since the storage unit 14 is partitioned into a first storage chamber 31 and a second storage chamber 32 by the partition wall structure 22, the first storage chamber 31 stores the object to be collected to be collected into the first culture bottle B1. The object to be collected to be collected into the second culture bottle B2 can be stored in the second storage chamber 32. This eliminates the need to manually measure and collect the object to be collected along the scale lines, making the work easier and reducing measurement errors. Therefore, according to the collection kit 10, it is possible to suppress variations in the amount of the object to be collected introduced into the first culture bottle B1 and the second culture bottle B2.

The partition structure 22 includes a partition main body 24 in which a communication passage 241 is formed, and a slide member 26 that is movable relative to the partition main body 24 and can open and close the communication passage 241. Therefore, the partition structure 22 can be opened and closed. It can be constructed with a simple structure.

Since the hydrophilic filter 30 is disposed adjacent to the partition structure 22, when the sample is transferred from the first storage chamber 31 to the second culture bottle B2, the hydrophilic filter 30 prevents air from flowing from the second storage chamber 32 into the first storage chamber 31. This makes it possible to prevent air from entering the second culture bottle B2. Therefore, the second culture bottle B2 can be used as a culture bottle for anaerobic bacteria.

The storage section 14 has a first cylinder 141 and a second cylinder 142 that can rotate relative to each other. With this configuration, the user can easily open and close the partition structure 22 by holding the first cylinder 141 with one hand and the second cylinder 142 with the other hand and rotating the first cylinder 141 and the second cylinder 142 relative to each other.

The storage section 14 is not limited to a configuration including a first cylinder 141 and a second cylinder 142 that are rotatable relative to each other. In this case, instead of the partition structure 22 according to the first configuration example shown in Figs. 1 and 2, for example, the partition structure 22B according to the second configuration example shown in Fig. 8 or the partition structure 22C according to the third configuration example shown in Fig. 9 may be used.

In FIG. 8, a slide member 26B having an operating protrusion 56 is arranged to overlap the partition main body 24. As shown in FIG. The operation projection 56 projects to the outside through an insertion hole 58 provided in the peripheral wall of the housing portion 14B. The slide member 26B is rotatable with respect to the housing portion 14B. The user can switch the partition wall structure 22B between an open state and a closed state by pinching the operation projection 56 with fingers and rotating the slide member 26B.

In FIG. 9, a communication passage 243 is provided in the partition main body 24C of the partition structure 22C. The slide member 26C is stacked on the partition main body 24C and is slidable in a direction perpendicular to the axis AX of the housing portion 14C. The operating shaft portion 60 extends from the slide member 26C and penetrates the peripheral wall portion of the housing portion 14C in a fluid-tight manner. A tab 62 is provided at the tip of the operating shaft portion 60. The user can switch the partition structure 22C between an open state and a closed state by pinching the tab 62 with fingers and linearly sliding the slide member 26C.

A collection kit 100 according to the second embodiment shown in FIG. 10 includes an inflow tube 12, a housing section 140, an air vent 16, and an adapter 20. Regarding the collection kit 100, descriptions of parts similar to those of the collection kit 10 according to the first embodiment shown in FIG. 1 etc. will be omitted as appropriate.

As shown in FIG. 10, the storage unit 140 has a first storage chamber 310 and a second storage chamber 320 capable of storing the object to be collected. The interior of the storage unit 140 is divided into the first storage chamber 310 and the second storage chamber 320 by a partition structure 220 extending in the vertical direction. The first storage chamber 310 and the second storage chamber 320 are arranged side by side. The inflow tube 12 is connected to the first storage chamber 310 via the boss portion 143 of the storage unit 140. The air vent 16 is connected to the upper part of the second storage chamber 320.

The partition structure 220 includes a partition main body 240 that extends vertically within the housing portion 140, and a slide member 260 that is slidable in the vertical direction with respect to the partition main body 240. A communication passage 244 is provided at the upper end of the partition main body 240. The slide member 260 is vertically slidable between a position where the communication path 244 is opened and a position where the communication path 244 is closed.

As shown in FIG. 11, a guide protrusion 263 extending in the vertical direction is provided on the inner wall of the storage section 140, and the guide protrusion 263 guides the slide member 260 in the vertical direction. An operating shaft portion 264 extends upward from the slide member 260 and penetrates the upper wall of the storage section 140 in a liquid-tight manner. A tab 266 is provided at the upper end of the operating shaft portion 264. The user can switch the partition structure 220 between an open state and a closed state by pinching the tab 266 with his/her fingers and sliding the slide member 260 in the vertical direction. Note that instead of providing the operating shaft portion 264 on the slide member 260, an operating protrusion protruding in the horizontal direction may be provided on the slide member 260. In this case, the operating protrusion protrudes to the outside through an insertion hole provided on the side wall of the storage section 140. The slide member 260 has a shape that closes the insertion hole so that the platelet preparation does not leak through the insertion hole.

As shown in FIG. 10, a hydrophilic filter 246 is fixed to the partition main body 240 so as to cover the communication path 244.

The collection kit 100 is used as follows. In this embodiment, a collection method in which the collection kit 100 is used to dispense a platelet preparation into two culture bottles B1 and B2 will be briefly described. Note that descriptions of parts that are similar to the method of using the collection kit 10 according to the first embodiment will be omitted as appropriate.

The platelet bag 50 (see FIG. 3) is joined to the collection kit 100 (joining process). Next, the platelet preparation is introduced into the storage section 140 (introduction process). In this case, the platelet preparation is first stored in the first storage chamber 310. When the first storage chamber 310 is filled with the platelet preparation, the platelet preparation flows from the first storage chamber 310 to the second storage chamber 320 via the communication passage 244. When a predetermined amount of platelet preparation is stored in the first storage chamber 310 and the second storage chamber 320, the partition structure 220 is switched to a closed state, and the platelet bag 50 is separated from the inflow tube 12.

Next, the first culture bottle B1 is connected to the adapter 20, and the platelet preparation is transferred from the first storage chamber 310 to the culture bottle B1 (first transfer step). After a predetermined amount of platelet preparation is collected in the culture bottle B1, the culture bottle B1 is removed from the adapter 20. Next, the collection kit 100 is turned sideways, and the platelet preparation is transferred from the second storage chamber 320 to the first storage chamber 310 (transfer step). Next, the second culture bottle B2 is connected to the adapter 20, and the platelet preparation is transferred from the first storage chamber 310 to the culture bottle B2 (second transfer step). After a predetermined amount of platelet preparation is introduced into the culture bottle B2, the culture bottle B2 is removed from the adapter 20.

Through the above steps, collection of the platelet preparation using the collection kit 100 is completed.

The present invention is not limited to the above disclosure, and various configurations may be adopted without departing from the gist of the present invention.

DESCRIPTION OF SYMBOLS 10, 100... Collection kit 12... Inflow tube 14, 14B, 14C, 140... Accommodation part 16... Air vent 20... Adapter 22, 22B, 22C, 220... Partition structure 24, 24C, 240... Partition body 26, 26B, 26C, 260...Slide member

Claims (5)

an inflow tube to which a medical bag containing the sample to be collected is connected;
A storage section connected downstream of the inflow tube and having a first storage chamber and a second storage chamber capable of storing the collection object;
an air vent connected to an upper portion of the second storage chamber and configured to exhaust air from the storage portion;
an adapter connected to the first storage chamber and connectable to a culture bottle;
the inlet tube is connected to the first chamber,
A collection kit, wherein the storage section has an openable and closable partition structure that separates the first storage chamber and the second storage chamber. 2. The collection kit of claim 1,
The collection kit includes a partition structure having a partition body in which a communication passage is formed, and a slide member that is displaceable relative to the partition body and can open and close the communication passage. 3. The collection kit of claim 2,
a hydrophilic filter disposed adjacent to the partition structure;
A collection kit, wherein when the partition structure is in an open state, the first storage chamber and the second storage chamber are in communication with each other via the communication passage and the hydrophilic filter. The collection kit according to claim 2 or 3,
The accommodating portion has a cylindrical first body having the first accommodating chamber, and a cylindrical second cylindrical body having the second accommodating chamber,
the first cylindrical body is provided with the partition main body,
the second cylindrical body is provided with the slide member;
The first cylindrical body and the second cylindrical body are fluid-tightly connected to each other so as to be relatively rotatable about the axis of the accommodating part,
A collection kit in which the partition wall structure opens and closes as the first cylinder and the second cylinder rotate relative to each other. A collection method in which a collection target is collected into two culture bottles using a collection kit,
The collection kit includes:
an inflow tube to which a medical bag containing the object to be collected is connected;
a storage section connected downstream of the inflow tube and having a first storage chamber and a second storage chamber capable of accommodating the object to be collected;
an air vent connected to an upper part of the second storage chamber and discharging air from the storage section;
an adapter connected to the first storage chamber and connectable to a culture bottle,
the inflow tube is connected to the first storage chamber,
The storage section has an openable and closable partition structure that partitions the first storage chamber and the second storage chamber,
The collection method is
a joining step of joining the medical bag to the inflow tube;
an introduction step of introducing the object to be collected into the first storage chamber and the second storage chamber through the inflow tube while keeping the partition structure open;
switching the partition structure to a closed state;
a first transfer step of connecting a first culture bottle to the adapter while keeping the partition structure in a closed state, and transferring the collection target from the first storage chamber to the first culture bottle;
A collection method comprising: a second transfer step of connecting a second culture bottle to the adapter and transferring the object to be collected to the second culture bottle.

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