JP2019024494A - チオエステル結合加水分解酵素を用いたキラルなカルボン酸化合物の不斉合成方法 - Google Patents
チオエステル結合加水分解酵素を用いたキラルなカルボン酸化合物の不斉合成方法 Download PDFInfo
- Publication number
- JP2019024494A JP2019024494A JP2018141313A JP2018141313A JP2019024494A JP 2019024494 A JP2019024494 A JP 2019024494A JP 2018141313 A JP2018141313 A JP 2018141313A JP 2018141313 A JP2018141313 A JP 2018141313A JP 2019024494 A JP2019024494 A JP 2019024494A
- Authority
- JP
- Japan
- Prior art keywords
- group
- general formula
- different
- substituent
- represented
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C*(C)(C)ON* Chemical compound C*(C)(C)ON* 0.000 description 3
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017148352 | 2017-07-31 | ||
| JP2017148352 | 2017-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2019024494A true JP2019024494A (ja) | 2019-02-21 |
Family
ID=65233946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018141313A Pending JP2019024494A (ja) | 2017-07-31 | 2018-07-27 | チオエステル結合加水分解酵素を用いたキラルなカルボン酸化合物の不斉合成方法 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP2019024494A (fr) |
| WO (1) | WO2019026800A1 (fr) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4682310B2 (ja) * | 2004-12-28 | 2011-05-11 | 独立行政法人産業技術総合研究所 | 天然型l−システインまたはその誘導体を用いたホタル発光基質の生合成システム及び本システムを含んだ発光基質溶液 |
-
2018
- 2018-07-27 JP JP2018141313A patent/JP2019024494A/ja active Pending
- 2018-07-27 WO PCT/JP2018/028295 patent/WO2019026800A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019026800A1 (fr) | 2019-02-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Classen et al. | Stereoselective enzyme cascades: An efficient synthesis of chiral γ-butyrolactones | |
| JP5474556B2 (ja) | 有機溶媒中でリパーゼを用いる短鎖レチニルエステル及び長鎖酸又は長鎖エステルからの長鎖レチニルエステルの製造方法 | |
| JPS61239899A (ja) | 光学活性アルフア‐アリールアルカン酸の生物工学的製造方法 | |
| CN108546720B (zh) | 一种立体选择性酶催化水解制备(s)-2-苯基丁酸的方法 | |
| EP0330529A1 (fr) | Procédé de préparation d'acides aryl-2 propioniques optiquement actifs | |
| Felfer et al. | The substrate spectrum of mandelate racemase: minimum structural requirements for substrates and substrate model | |
| EP0808308B1 (fr) | Procede de separation de carbinols | |
| EP0326482A1 (fr) | Procédé de préparation d'acides aryl-2 alkanoiques optiquement actifs | |
| JP2019024494A (ja) | チオエステル結合加水分解酵素を用いたキラルなカルボン酸化合物の不斉合成方法 | |
| JPH0657158B2 (ja) | 複合酵素系を使用するn‐アシルアミノ酸エステルのエナンチオ選択性加水分解 | |
| Lee et al. | Enantioselective hydrolysis of racemic naproxen methyl ester by two-step acetone-treated Candida rugosa lipase | |
| JP5443357B2 (ja) | 長鎖アルコールのエステルとその製造方法 | |
| KR100576276B1 (ko) | 합성 중간체의 신규 제조 방법 | |
| Li et al. | Simultaneous preparation of (S)-2-aminobutane and D-alanine or D-homoalanine via biocatalytic transamination at high substrate concentration | |
| JP5216762B2 (ja) | (s)−1−メチル−フェニルピペラジンの立体選択的合成 | |
| FR2829152A1 (fr) | Procede enzymatique pour la resolution enantiomerique d'acides amines | |
| Zhu et al. | Synthesis of optically pure (S)-2-acetylthio-3-benzenepropanoic acid via enzymatic resolution | |
| EP2069516B1 (fr) | Hydrolyse spécifique de l'ester (r) non protégé en n de l'acide 3-amino-3-arylpropionique | |
| JP5506658B2 (ja) | 好熱性古細菌由来エステラーゼを用いた光学活性カルボン酸の製造方法 | |
| JP2000023693A (ja) | 光学活性な2−アセチルチオ−3−フェニルプロピオン酸の製造方法 | |
| CA2724734A1 (fr) | Procede d'esterification de prostaglandines et de leurs analogues | |
| JP3219531B2 (ja) | 光学活性1−アリール−3−クロロ−1−プロパノール又はそのカルボン酸エステルの製造法 | |
| JP4658315B2 (ja) | 光学活性カルボン酸及びその対掌体エステルの製造方法 | |
| EP0396447A1 (fr) | Procédé de séparation énantiomériquement sélective des esters des acides halogéno-2 propioniques | |
| KR20180127420A (ko) | 삼중 결합-함유 광학 활성 카르복실산, 카르복실레이트 염 및 카르복실산 유도체의 제조 방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AA64 | Notification of invalidation of claim of internal priority (with term) |
Free format text: JAPANESE INTERMEDIATE CODE: A241764 Effective date: 20180821 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180831 |