JP2018143898A - Filtration filter device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a filtration filter device capable of improving filtration efficiency.SOLUTION: A filtration filter device includes: a metallic porous film (1); a housing (2) including the metallic porous film (1), and having a fluid inflow passage (21a) provided so as to face to a first principal surface (11) of the metallic porous film (1), and a fluid discharge passage (22a) provided so as to face to a second principal surface (12) of the metallic porous film (1); and an elastic body (3) provided on a clearance between the periphery of the metallic porous film (1) and the housing (2).SELECTED DRAWING: Figure 2

Description

  The present invention relates to a filtration filter device that filters a filtration object contained in a fluid.

  Conventionally, what was described in patent document 1 (for example, refer Unexamined-Japanese-Patent No. 2013-255780) is known as this kind of filtration filter device.

  The filtration filter device of patent document 1 is provided with the filtration filter which filters the filtration target object contained in the fluid, and the housing which encloses the said filtration filter. The housing is provided with a fluid inflow path and a fluid discharge path, and a filtration filter is disposed between them.

JP2013-255780A

  As an object to be filtered by a filtration filter device, there is a biological substance contained in a liquid. Many biological substances are very small, such as cells, bacteria, and viruses, and are difficult to collect again. For this reason, the improvement of filtration efficiency is calculated | required. However, according to the filter device of Patent Document 1, there is a problem that the filtration efficiency is not sufficient.

  An object of the present invention is to solve the above-described problems, and to provide a filtration filter device that can improve filtration efficiency.

In order to achieve the above object, a filtration filter device according to an aspect of the present invention comprises:
A metal porous membrane,
The metal porous membrane is included, and the fluid inflow passage provided to face the first main surface of the metal porous membrane and the second main surface of the metal porous membrane are provided. A housing having a fluid discharge path;
An elastic body provided in a gap between the outer peripheral portion of the metal porous membrane and the housing;
It is characterized by providing.

  According to the filtration filter device according to the present invention, the filtration efficiency can be improved.

It is a perspective view showing a schematic structure of a filtration filter device concerning an embodiment of the invention. It is a perspective view which shows a part of filtration filter device of FIG. 1 in a cross section. It is a disassembled perspective view of the filtration filter device of FIG. It is an expansion perspective view of a part of metallic porous membrane. It is a schematic sectional drawing which shows the modification which made thickness of the 1st elastic member thicker than the thickness of the 2nd elastic member. It is a schematic sectional drawing which shows the modification which comprised the elastic body only with the 1st elastic member. It is a schematic sectional drawing which shows the modification which formed the 1st elastic member and the 2nd elastic member in the taper shape so that opening area may become small as it approaches a metal porous film. It is a schematic sectional drawing which shows the modification comprised so that a 1st elastic member and a 2nd elastic member may mutually contact on the outer side of a metal porous film.

(Knowledge that became the basis of the present invention)
As a result of intensive studies to improve the filtration efficiency of the filtration object, the present inventors have obtained the following knowledge.

  In the filtration filter device of Patent Document 1, a filter made of a synthetic polymer material such as polybutylene terephthalate (PBT) or polyethylene terephthalate (PET) is used as the filtration filter. These synthetic polymer materials are known to have relatively high water absorption. For this reason, when a very small amount of liquid containing a biological substance is filtered by the filter, the liquid may be absorbed by the filter. For example, when a liquid containing 1 ml of a biological substance is filtered with a filter made of a polymer material, the liquid absorbed by the filter may be 0.1 ml. In this case, the filtration efficiency is lowered.

  In contrast, the present inventors have conceived that a metal porous film made of a metal material such as gold, silver, or copper is used as the filter. In this case, the metal material has an extremely low water absorption as compared with the synthetic polymer material, so that it is considered that the filtration efficiency is improved.

  However, when the metal porous membrane is used as the filtration filter, the present inventors have a new problem that the liquid containing the filtration target does not pass through the metal porous membrane and flows through the gap between the metal porous membrane and the housing. It was found that occurs. That is, in the structure in which the filtration filter is included in the housing, there is a considerable gap between the filtration filter and the housing. When a filter made of a synthetic polymer material is used as the filtration filter, the filter absorbs water and expands, thereby filling a gap between the filter made of the synthetic polymer material and the housing. For this reason, the liquid containing the filtration object passes through the inside of the synthetic polymer material filter without flowing through the gap between the synthetic polymer material filter and the housing. On the other hand, when a metal porous membrane is used as a filtration filter, the metal porous membrane does not expand or hardly expands, so that the gap between the metal porous membrane and the housing cannot be filled.

  As a result of intensive studies based on these novel findings, the present inventors have arranged an elastic body so as to seal the gap between the outer peripheral portion of the metal porous membrane and the housing, thereby making the filtration efficiency more than conventional. It was found that it can be improved. Based on these points, the present inventors have reached the following invention.

A filtration filter device according to an aspect of the present invention includes a metal porous membrane,
The metal porous membrane is included, and the fluid inflow passage provided to face the first main surface of the metal porous membrane and the second main surface of the metal porous membrane are provided. A housing having a fluid discharge path;
An elastic body provided in a gap between the outer peripheral portion of the metal porous membrane and the housing;
It is characterized by providing.

  According to this configuration, since the elastic body is provided in the gap between the outer peripheral portion of the metal porous membrane and the housing, the gap is sealed by the elastic body 3, and the filtration object contained in the fluid is contained in the gap. Can be suppressed. Thereby, filtration efficiency can be improved rather than the conventional structure. In addition, by providing an elastic body in the gap between the outer peripheral portion of the metal porous membrane and the housing, it is possible to suppress the need to increase the dimensional accuracy of the metal porous membrane. Further, the metal porous membrane can be fixed in the housing.

  The elastic body includes a first elastic member provided in a gap between the outer peripheral portion of the first main surface of the metal porous membrane and the housing, and an outer peripheral portion of the second main surface of the metal porous membrane. You may comprise with the 2nd elastic member provided in the clearance gap between the said housings. According to this configuration, the metal porous membrane is included in the housing in a state where the outer peripheral portion is sandwiched between the first elastic member and the second elastic member. For this reason, the load concerning the outer peripheral part of a metal porous film can be reduced rather than the structure which makes one or both of a 1st elastic member and a 2nd elastic member a rigid body. As a result, it is possible to use a thin metal porous film (for example, 0.05 μm). Further, even when the inner surface of the housing enclosing the metal porous membrane has surface roughness, the surface roughness can be absorbed by the elastic force of the first elastic member and the second elastic member. As a result, deformation of the metal porous film due to the surface roughness of the inner surface of the housing can be suppressed.

  The first elastic member and the second elastic member are preferably thicker than the metal porous membrane. According to this configuration, the metal porous film can be fixed in the housing by sandwiching the metal porous film having a small thickness between the first elastic member and the second elastic member having a large thickness.

  Further, the first elastic member and the second elastic member may be the same member. According to this configuration, it is not necessary to distinguish between the first elastic member and the second elastic member, and therefore manufacturing can be facilitated.

  The first elastic member may be thicker than the second elastic member. According to this configuration, the volume of the space formed by the inner peripheral surface of the first elastic member and the first main surface of the metal porous film can be increased. Thereby, the accumulation amount of the filtration target object in the space formed by the inner peripheral surface of the first elastic member and the first main surface of the metal porous membrane can be increased.

  The first elastic member may be an annular member, and may be formed in a tapered shape so that the opening area increases as the inner peripheral surface moves away from the first main surface of the metal porous membrane. According to this configuration, the volume of the space formed by the inner peripheral surface of the first elastic member and the first main surface of the metal porous film can be increased. Thereby, the accumulation amount of the filtration target object in the space formed by the inner peripheral surface of the first elastic member and the first main surface of the metal porous membrane can be increased. Further, the fluid flowing through the fluid inflow path can be guided to flow toward the metal porous membrane.

  The second elastic member may be an annular member, and may be formed in a tapered shape so that the opening area increases as the inner peripheral surface moves away from the second main surface of the metal porous membrane. According to this configuration, when the fluid is supplied from the fluid discharge path side and the filtration object filtered by the first main surface of the metal porous film is removed from the metal porous film (so-called backwashing), the fluid discharge path Can be induced to flow toward the metal porous membrane.

  Further, the first elastic member and the second elastic member may be formed such that the outer shape of each of the first elastic member and the second elastic member is larger than the outer shape of the metal porous membrane, and contact each other outside the metal porous membrane. According to this configuration, for example, even when a rotational force is applied to the outer peripheral portion of the metallic porous membrane when the housing is attached, the load on the outer peripheral portion of the metallic porous membrane can be reduced. As a result, the metal porous film can be prevented from being broken.

  The first elastic member may include a flat surface, and the flat surface may be in surface contact with the outer peripheral portion of the first main surface of the metal porous membrane. According to this structure, compared with the case where an O-ring having a circular cross section is used as the first elastic member, the first elastic member and the outer peripheral portion of the first main surface of the metal porous film can be brought into close contact with each other. It is possible to further suppress the fluid from passing between the first elastic member and the outer peripheral portion of the first main surface of the metal porous membrane.

  The second elastic member may have a flat surface, and the flat surface may be in surface contact with the outer peripheral portion of the second main surface of the metal porous membrane. According to this structure, compared with the case where an O-ring having a circular cross section is used as the second elastic member, the second elastic member and the outer peripheral portion of the second main surface of the metal porous film can be brought into close contact with each other. It is possible to further suppress the fluid from passing between the second elastic member and the outer peripheral portion of the second main surface of the metal porous membrane.

  Further, the elastic body may be configured only by a first elastic member provided in a gap between the outer peripheral portion of the first main surface of the metal porous membrane and the housing. According to this configuration, since the first elastic member is provided on the fluid inflow path side, the filtration object filtered by the first main surface of the metal porous membrane is made to pass through the inner peripheral surface of the first elastic member and the metal. It can accumulate in the space formed by the first main surface of the porous membrane. Thereby, the filtration processing amount can be increased.

  The elastic body may be made of a resin material or a rubber material. According to this configuration, the dimensional accuracy between the metal porous film and the housing can be lowered by the elastic force of the resin material or the rubber material. Further, the metal porous membrane can be fixed in the housing.

  The housing includes at least two members, a first housing portion provided with the fluid inflow passage and a second housing portion provided with the fluid discharge passage, and the first housing portion and the second housing. The unit may be configured to be detachable from each other. According to this configuration, the metal porous membrane can be exchanged by removing the first housing part and the second housing part. Moreover, the filtration object filtered with the metal porous film can be observed with a microscope or the like.

  The distance between the surface of the first housing part and the surface of the second housing part facing each other with the metal porous film interposed therebetween may be adjustable. According to this configuration, it is possible to further suppress the necessity of increasing the dimensional accuracy of the housing. Moreover, various elastic modulus can be used as the elastic body. Furthermore, metal porous films having different thicknesses can be held in the same housing.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings.

(Embodiment)
FIG. 1 is a perspective view showing a schematic configuration of a filtration filter device according to an embodiment of the present invention. FIG. 2 is a perspective view showing a part of the filtration filter device of FIG. 1 in cross section. FIG. 3 is an exploded perspective view of the filtration filter device of FIG.

  As shown in FIGS. 1 to 3, the filtration filter device according to the first embodiment includes a metal porous membrane 1 that filters a filtration object contained in a fluid, and a housing 2 that encloses the metal porous membrane 1. It has. An elastic body 3 is provided in a gap between the outer peripheral portion 1A of the metal porous film 1 and the housing 2 so as to seal the gap.

  In the present embodiment, the object to be filtered is a biological substance contained in the liquid. In the present specification, the “biological substance” means a substance derived from a living organism such as a cell (eukaryotic organism), a bacterium (eubacteria), or a virus. Examples of cells (eukaryotes) include eggs, sperm, induced pluripotent stem cells (iPS cells), ES cells, stem cells, mesenchymal stem cells, mononuclear cells, single cells, cell masses, suspension cells, and adhesions. Includes sex cells, nerve cells, leukocytes, lymphocytes, cells for regenerative medicine, autologous cells, cancer cells, circulating cancer cells (CTC), HL-60, HELA, and fungi. Examples of bacteria (true bacteria) include gram positive bacteria, gram negative bacteria, Escherichia coli, and tuberculosis bacteria. Examples of the virus include DNA virus, RNA virus, rotavirus, (bird) influenza virus, yellow fever virus, dengue fever virus, encephalitis virus, hemorrhagic fever virus, and immunodeficiency virus.

  In the present embodiment, the metal porous membrane 1 is a porous membrane that separates biological substances. FIG. 4 is an enlarged perspective view of a part of the metal porous membrane 1.

  As shown in FIG. 4, the metal porous membrane 1 has a first main surface 11 and a second main surface 12 that face each other. The metal porous film 1 is provided with a plurality of through holes 13 that penetrate the first main surface 11 and the second main surface 12. The through-hole 13 separates a biological substance from the liquid. The shape and size of the through-hole 13 are appropriately set according to the shape and size of the biological material. The through holes 13 are, for example, arranged at regular intervals or periodically. The shape of the through-hole 13 is, for example, a square when viewed from the first main surface 11 or the second main surface 12 side of the metal porous membrane 1. The size of the through-hole 13 is, for example, from 0.1 μm to 50 μm in length and from 0.1 μm to 50 μm in width. The interval between the through holes 13 is, for example, larger than 1 time and not larger than 10 times, more preferably not larger than 3 times that of the through holes 13. Moreover, the aperture ratio of the through-hole 13 in the metal porous membrane 1 is, for example, 10% or more.

  Examples of the material of the metal porous film 1 include gold, silver, copper, nickel, stainless steel, palladium, titanium, and alloys thereof. The dimensions of the metal porous membrane 1 are, for example, a diameter of 8 mm and a thickness of 0.05 μm to 100 μm. The outer shape of the metal porous membrane 1 is, for example, circular.

  The housing 2 includes a first housing part 21 and a second housing part 22. When the first housing part 21 and the second housing part 22 are detachably engaged with each other, the metal porous membrane 1 is interposed between the first housing part 21 and the second housing part 22 as shown in FIG. A space S1 is formed.

  The first housing portion 21 is provided with a fluid inflow passage 21 a at a position facing the first main surface 11 of the metal porous membrane 1. Specifically, the first housing portion 21 has a structure in which one end portion of the cylindrical body 21c is connected so as to penetrate the center portion of the disc body 21b. The inside of the cylindrical body 21c becomes the fluid inflow path 21a.

  In addition, a pair of engagement pieces 21d and 21d are provided at positions facing each other across the central portion of the disc body 21b. Each engagement piece 21d is provided so as to protrude radially outward from the disc body 21b. The outer shape of each engagement piece 21d is formed in an arc shape centered on the center of the disc body 21b. Each engagement piece 21d has an inclined surface 21e that is inclined so as to approach the metal porous membrane 1 side toward the upstream side in the rotation direction when the first housing portion 21 is rotated around the axis of the cylindrical body 21c. have.

  The second housing portion 22 is provided with a fluid discharge path 22 a at a position facing the second main surface 12 of the metal porous membrane 1. Specifically, the second housing portion 22 has a structure in which one end portion of the cylindrical body 22c is connected so as to penetrate the center portion of the disc body 22b. The inside of the cylindrical body 22c is a fluid discharge path 22a.

  A large-diameter cylindrical body 22d is provided on the outer peripheral portion of the disc body 22b so as to protrude in the opposite direction to the cylindrical body 22c. The metal porous membrane 1, the disk body 21b and the engaging piece 21d of the first housing portion 21, and the elastic body 3 are accommodated in a space surrounded by the disk body 22b and the large-diameter cylindrical body 22d. .

  A pair of engaged pieces 22e and 22e that can be engaged with the engaging pieces 21d and 21d of the first housing portion 21 are provided at the upper end of the large-diameter cylindrical body 22d. The pair of engaged pieces 22e and 22e are provided so as to protrude radially inward at positions facing each other across the central portion of the disc body 22b in plan view. The engaged piece 22e and the engaging piece 21d are configured such that the first housing portion 21 rotates around the axis of the cylindrical body 21c (or the first piece) in a state where the engaging piece 21d is accommodated in the space inside the large-diameter cylindrical body 22d. The two housing portions 22 are engaged with each other by being rotated (around the axis of the cylindrical body 22c). Thereby, the relative position of the 1st housing part 21 and the 2nd housing part 22 is fixed.

  Here, each engaging piece 21d is provided with the inclined surface 21e as described above. For this reason, when the first housing part 21 is rotated around the axis of the cylindrical body 21c (or the second housing part 22 is rotated around the axis of the cylindrical body 22c), the engaged piece 22e makes the inclined surface 21e a porous metal. Press toward the membrane 1 side. As a result, the disc body 21 b of the first housing portion 21 approaches the disc body 22 b of the second housing portion 22. Therefore, the thickness (height) of the space S1 containing the metal porous membrane 1 can be adjusted by adjusting the rotation amount of the first housing portion 21 (or the second housing portion 22). That is, the distance between the surface of the first housing portion 21 and the surface of the second housing portion 22 that are opposed to each other with the metal porous membrane 1 interposed therebetween is adjustable.

  On the other hand, with the engaged piece 22e and the engaging piece 21d engaged, the first housing portion 21 is reversed around the axis of the cylindrical body 21c (or the second housing portion 22 is rotated around the axis of the cylindrical body 22c). By rotating in the direction, the engaged piece 22e and the engaging piece 21d are disengaged. Thereby, the 1st housing part 21 and the 2nd housing part 22 can be removed.

  In addition, a protrusion 22 f that restricts the movement of the metal porous film 1 and the elastic body 3 in the surface direction is provided on the inner side of the outer peripheral portion of the disc body 22 b. The protrusion 22f is formed in an annular shape, for example. The metal porous membrane 1 and the elastic body 3 are positioned and positioned inside the protrusion 22f. Thereafter, the first housing portion 21 and the second housing portion 22 are attached so that the engaged piece 22e and the engaging piece 21d are engaged, so that the metal porous membrane 1 and the elastic body 3 are placed in the space S1. Included. The length of the protrusion 22 f is set shorter than the total thickness of the elastic body 3 and the metal porous film 1 in order to make the elastic force of the elastic body 3 function.

  Examples of the material of the first housing part 21 and the second housing part 22 include polyethylene, polypropylene, polycarbonate, ABS resin, polyacetal, polyetherimide, and transparent resin.

  As shown in FIG. 2 or 3, the elastic body 3 includes a first elastic member 31 and a second elastic member 32. The first elastic member 31 is provided in the gap between the outer peripheral portion of the first main surface 11 of the metal porous membrane 1 and the first housing portion 21. The second elastic member 32 is provided in the gap between the outer peripheral portion of the second main surface 12 of the metal porous membrane 1 and the second housing portion 22.

  The first elastic member 31 and the second elastic member 32 are formed in an annular shape. The first elastic member 31 includes a flat surface 31a and is provided so as to be in surface contact with the outer peripheral portion of the first main surface 11 of the metal porous film 1 at the flat surface 31a. The second elastic member 32 includes a flat surface 32a and is provided so as to be in surface contact with the outer peripheral portion of the second main surface 12 of the metal porous film 1 at the flat surface 32a. In the present embodiment, the first elastic member 31 and the second elastic member 32 have a rectangular cross section in the inelastically deformed state.

  The first elastic member 31 and the second elastic member 32 are formed thicker than the metal porous film. The thicknesses of the first elastic member 31 and the second elastic member 32 are, for example, 10 μm or more and 10 mm or less in a range that does not fall below the thickness of the metal porous membrane. Examples of the material of the first elastic member 31 and the second elastic member 32 include a resin material such as silicon resin, and a rubber material such as nitrile rubber and butadiene rubber. In the present embodiment, the same member (size, material, etc.) is used for the first elastic member 31 and the second elastic member 32.

  According to the present embodiment, since the elastic body 3 provided in the gap between the outer peripheral portion 1A of the metal porous membrane 1 and the housing 2 is provided, the gap is sealed by the elastic body 3 and included in the fluid. It can suppress that the filtration target object passes. Thereby, filtration efficiency can be improved rather than the conventional structure. In addition, by providing the elastic body 3 in the gap between the outer peripheral portion 1A of the metal porous membrane 1 and the housing 2, it is possible to suppress the necessity of increasing the dimensional accuracy of the metal porous membrane 1. That is, when a rigid body is provided in the gap between the metallic porous membrane 1 and the housing 2, the rigid body is not deformed, and therefore the thickness of the metallic porous membrane 1 must be set to the size of the gap. On the other hand, when the elastic body 3 is provided in the gap between the metal porous membrane 1 and the housing 2, the elastic body 3 may be used even if the thickness of the metal porous membrane 1 is slightly different from the dimension of the gap. By deforming itself, the metal porous membrane 1 can be accommodated in the gap. As a result, the metal porous membrane 1 can be fixed in the space S <b> 1 in the housing 2.

  In addition, according to the present embodiment, the metal porous membrane 1 is enclosed in the housing 2 with the outer peripheral portion 1 </ b> A being sandwiched between the first elastic member 31 and the second elastic member 32. Thereby, the load concerning 1 A of outer peripheral parts of the metal porous film 1 can be reduced rather than the structure which makes one or both of the 1st elastic member 31 and the 2nd elastic member 32 a rigid body. As a result, it is possible to use a thin metal porous film 1 (for example, 0.05 μm). In addition, the inner surface of the housing 2 that encloses the metal porous membrane 1 (surface that contacts the flat surface 31a of the first elastic member 31 and the flat surface 32a of the second elastic member 32) has surface roughness. Also, the surface roughness can be absorbed by the elastic force of the first elastic member 31 and the second elastic member 32. As a result, the metal porous membrane 1 can be prevented from being deformed by the surface roughness of the inner surface of the housing 2.

  Moreover, according to this Embodiment, since the 1st elastic member 31 is provided in the fluid inflow channel side, the 1st elastic member 31 filters the filtration target object filtered by the 1st main surface 11 of the metal porous membrane 1. FIG. Can be accumulated in a space formed by the inner peripheral surface of the metal and the first main surface 11 of the metal porous membrane 1. Thereby, the filtration processing amount can be increased.

  Further, according to the present embodiment, the first elastic member 31 and the second elastic member 32 are configured to be thicker than the metal porous membrane 1. According to this configuration, the metallic porous membrane 1 is sandwiched between the thick first elastic member 31 and the second elastic member 32 so that the metallic porous membrane 1 is placed in the space in the housing 2. Can be fixed to S1.

  Moreover, according to this Embodiment, the 1st elastic member 31 is comprised so that the outer peripheral part of the 1st main surface 11 of the metal porous film 1 may be in surface contact with the flat surface 31a. Thereby, compared with the case where an O-ring having a circular cross section is used as the first elastic member 31, the first elastic member 31 and the outer peripheral portion of the first main surface 11 of the metal porous film 1 can be brought into close contact with each other. The fluid can be further prevented from passing between the first elastic member 31 and the outer peripheral portion of the first main surface 11 of the metal porous membrane 1.

  Further, according to the present embodiment, since the second elastic member 32 is provided on the fluid discharge path side, the fluid is supplied from the fluid discharge path side and filtered by the first main surface 11 of the metal porous membrane 1. It is possible to easily remove the object to be filtered from the metal porous membrane 1 (so-called backwashing).

  Moreover, according to this Embodiment, the 2nd elastic member 32 is comprised so that the outer peripheral part of the 2nd main surface 12 of the metal porous film 1 may be in surface contact with the flat surface 32a. Thereby, compared with the case where an O-ring having a circular cross section is used as the second elastic member 32, the second elastic member 32 and the outer peripheral portion of the second main surface 12 of the metal porous film 1 can be brought into close contact with each other. The fluid can be further prevented from passing between the second elastic member 32 and the outer peripheral portion of the second main surface 12 of the metal porous membrane 1.

  Moreover, according to this Embodiment, since the same member is used for the 1st elastic member 31 and the 2nd elastic member 32, it is not necessary to distinguish the 1st elastic member 31 and the 2nd elastic member 32. . Thereby, manufacture of a filtration filter device can be made easy.

  Moreover, according to this Embodiment, since the housing 2 is comprised by the 1st housing part 21 and the 2nd housing part 22 which can mutually be attached or detached, the 1st housing part 21 and the 2nd housing part 22 are removed. Thus, the metal porous membrane 1 can be exchanged. Moreover, the filtration object filtered with the metal porous membrane 1 can be observed with a microscope or the like.

  Further, according to the present embodiment, the distance between the surface of the first housing part 21 and the surface of the second housing part 22 facing each other with the metal porous membrane 1 interposed therebetween is configured to be adjustable. Thereby, the necessity for making the dimensional accuracy of the housing 2 high can be suppressed further. In addition, various elastic moduli can be used as the elastic body 3.

  In the present embodiment, the filtering object is a biological substance contained in the liquid, but the present invention is not limited to this. The object to be filtered may be a substance contained in a gas. That is, the filtration object may be a substance contained in the fluid, and may be, for example, PM2.5 contained in the air.

  Moreover, in this Embodiment, although the metal porous membrane 1 shall be used in order to filter a biological substance from a liquid, this invention is not limited to this. For example, the metal porous membrane 1 may be used to concentrate a liquid.

  In the present embodiment, the first elastic member 31 and the second elastic member 32 are the same member, but the present invention is not limited to this. For example, as shown in FIG. 5, the first elastic member 31 may be thicker than the second elastic member 32. According to this configuration, the volume of the space formed by the inner peripheral surface of the first elastic member 31 and the first main surface 11 of the metal porous membrane 1 can be increased. Thereby, the accumulation amount of the filtration target object in the space formed by the inner peripheral surface of the first elastic member 31 and the first main surface 11 of the metal porous membrane 1 can be increased.

  Moreover, in this Embodiment, although the elastic body 3 was comprised by the 1st elastic member 31 and the 2nd elastic member 32, this invention is not limited to this. For example, in the case where only the filtration object is filtered by the metal porous membrane 1 and the backwashing is not performed, the elastic body 3 may be composed of only the first elastic member 31 as shown in FIG. Good.

  In the present embodiment, the first elastic member 31 has a rectangular cross section, but the present invention is not limited to this. For example, as shown in FIG. 7, the first elastic member 31 may be formed in a tapered shape so that the opening area increases as the distance from the first main surface 11 of the metal porous membrane 1 increases. According to this configuration, the volume of the space formed by the inner peripheral surface of the first elastic member 31 and the first main surface 11 of the metal porous membrane 1 can be increased. Thereby, the accumulation amount of the filtration target object in the space formed by the inner peripheral surface of the first elastic member 31 and the first main surface 11 of the metal porous membrane 1 can be increased. Further, the fluid flowing through the fluid inflow path 21 a can be guided to flow toward the metal porous membrane 1.

  In the present embodiment, the second elastic member 32 has a rectangular cross section, but the present invention is not limited to this. For example, as shown in FIG. 7, the second elastic member 32 may be formed in a tapered shape so that the opening area increases as the distance from the second main surface 12 of the metal porous membrane 1 increases. According to this configuration, when backwashing, the fluid that flows back through the fluid discharge path 22a can be guided to flow toward the metal porous membrane 1.

  Further, in the present embodiment, the outer shape of the first elastic member 31 and the second elastic member 32 is configured to match the outer shape of the metal porous film 1, but the present invention is not limited to this. For example, as shown in FIG. 8, the first elastic member 31 and the second elastic member 32 are formed so that their outer shapes are larger than the outer shape of the metal porous film 1 and contact each other outside the metal porous film 1. It may be configured to. According to this configuration, for example, even when a rotational force is applied to the outer peripheral portion 1A of the metallic porous membrane 1 when attaching the first housing portion 21 and the second housing portion 22, the outer periphery of the metallic porous membrane 1 The load concerning the part 1A can be reduced. As a result, the metal porous membrane 1 can be prevented from being broken.

  In the present embodiment, the relative position between the first housing portion 21 and the second housing portion 22 is fixed by engaging the engaging piece 21d and the engaged piece 22e. It is not limited to. For example, you may provide the clamp member which fixes the relative position of the 1st housing part 21 and the 2nd housing part 22 separately.

  Moreover, in this Embodiment, although the housing 2 shall be comprised by two members, the 1st housing part 21 and the 2nd housing part 22, this invention is not limited to this. The housing 2 may be composed of three or more members.

Example 1
Next, the filtration filter device according to the first embodiment will be described.

  First, after the second elastic member 32, the metal porous membrane 1, and the first elastic member 31 are sequentially laminated on the disc body 22b of the second housing portion 22, the engaging piece 21d and the engaged piece 22e are engaged. The filtration filter device shown in FIG. 1 or FIG. 2 was produced.

  Here, the material of the 1st housing part 21 and the 2nd housing part 22 was made into transparent resin. The diameter of the disc body 21b of the first housing part 21 was 24 mm. The cylindrical body 21c had an outer diameter of 6 mm, an inner diameter of 4 mm, and a length of 10 mm. The diameter of the disc body 22b of the second housing part 22 was 34 mm, the outer diameter of the cylindrical body 22c was 6 mm, the inner diameter was 4 mm, and the length was 10 mm. The outer diameter of the large-diameter cylindrical body 22d was 34 mm, the inner diameter was 30 mm, and the height was 7.15 mm. Further, the length from the outer end portion of the cylindrical body 21c of the first housing portion 21 to the outer end portion of the cylindrical body 22c of the second housing portion 22 was set to 25 mm. The thickness of the space S1 between the first housing part 21 and the second housing part 22 was 1.8 mm.

  The metal porous membrane 1 had a diameter of 15 mm and a thickness of 20 μm. The through hole 13 of the metal porous membrane 1 was a square hole having a side of 1.9 μm. The inner diameter of the protrusion 22f surrounding the metal porous membrane 1 was 16 mm.

  The material of the first elastic member 31 and the second elastic member 32 was made of silicon resin. The outer diameters of the first elastic member 31 and the second elastic member 32 were 15.5 mm, the inner diameter was 13 mm, and the thickness was 1 mm.

5 ml of liquid containing 1 × 10 ⁶ standard particles having a diameter of 5 μm was passed through the fluid inflow passage 21a of the filtration filter device according to Example 1 manufactured in this way, and the state was visually observed. As a result, all the liquid passed through the metal porous membrane 1, and it was not possible to confirm the liquid that was not filtered. Moreover, it was 5 mg when the quantity of the liquid which passed the metal porous membrane 1 was measured with the electronic balance. Moreover, when the liquid which passed the metal porous film 1 was measured with the particle size distribution meter, the standard particle was not able to be observed.

(Comparative Example 1)
A filtration filter device according to Comparative Example 1 was produced in the same manner as the filtration filter device according to Example 1 except that the elastic body 3 was not provided.

  The liquid was allowed to pass through the fluid inflow path 21a of the filtration filter device according to Comparative Example 1 manufactured as described above, and the state was visually observed. As a result, it was confirmed that a part of the liquid passes through the gap between the outer peripheral portion 1A of the metal porous membrane 1 and the housing 2 (there is liquid leakage).

(Comparative Example 2)
A filtration filter device according to Comparative Example 2 was produced in the same manner as the filtration filter device according to Example 1 except that the elastic body 3 was not provided and a PTFE filter was used instead of the metal porous membrane. As the PTFE filter, a filter manufactured by Wintec, model TFG-110, pore size of 1-2 μm, and thickness of 250 μm was used.

  The liquid was allowed to pass through the fluid inflow path 21a of the filtration filter device according to Comparative Example 2 manufactured as described above, and the state was visually observed. As a result, it was confirmed that a part of the liquid passes through the gap between the outer peripheral portion 1A of the metal porous membrane 1 and the housing 2 (there is liquid leakage). This phenomenon occurred remarkably in the initial stage when the liquid started to flow into the fluid inflow path 21a.

(Comparative Example 3)
A filtration filter device according to Comparative Example 3 was produced in the same manner as the filtration filter device according to Example 1, except that the elastic body 3 was not provided and filter paper was used instead of the metal porous membrane. As the filter paper, cellulose filter paper manufactured by Whatman, grade 3MM Chr, and thickness of 340 μm was used.

  The liquid was allowed to pass through the fluid inflow path 21a of the filtration filter device according to Comparative Example 3 thus manufactured, and the state was visually observed. As a result, it was confirmed that the filter paper expands in the thickness direction due to the water absorption of the filter paper. Moreover, it was 4.8 mg when the quantity of the liquid which passed the metal porous film 1 was measured with the electronic balance. That is, it was confirmed that 0.2 mg of liquid was absorbed by the filter paper.

(Example 2)
The filtration filter device according to the second embodiment is the same as the filtration filter device according to the first embodiment except that the thickness of the metal porous membrane 1 is changed to 2 μm and the rotation amount of the first housing portion 21 is increased. Was made.

5 ml of a cell culture solution containing 1 × 10 ⁶ cells HL60 was passed through the fluid inflow passage 21a of the filtration filter device according to Example 2 manufactured as described above. Then, the 1st housing part 21 was removed from the 2nd housing part 22, the metal porous membrane 1 which filtered the said cell culture solution was taken out, and it observed with the microscope. As a result, the cells filtered on the metal porous membrane 1 could be easily observed.

  Although the present invention has been fully described in connection with preferred embodiments with reference to the accompanying drawings, various variations and modifications will be apparent to those skilled in the art. Such changes and modifications are to be understood as being included therein, so long as they do not depart from the scope of the present invention according to the appended claims.

  INDUSTRIAL APPLICATION This invention is useful for the filtration filter device which filters the filtration target object contained in fluids, such as a biological material and PM2.5.

DESCRIPTION OF SYMBOLS 1 Metal porous film 1A Outer peripheral part 2 Housing 3 Elastic body 11 1st main surface 12 2nd main surface 13 Through-hole 21 1st housing part 21a Fluid inflow path 21b Disc body 21c Cylindrical body 21d Engagement piece 21e Inclined surface 22 2nd housing part 22a Fluid discharge path 22b Disc body 22c Cylindrical body 22d Large diameter cylindrical body 22e Engagement piece 22f Protrusion part 31 1st elastic member 31a Flat surface 32 2nd elastic member 32a Flat surface

Claims (14)

A metal porous membrane,
The metal porous membrane is included, and the fluid inflow passage provided to face the first main surface of the metal porous membrane and the second main surface of the metal porous membrane are provided. A housing having a fluid discharge path;
An elastic body provided in a gap between the outer peripheral portion of the metal porous membrane and the housing;
A filtration filter device comprising:   The elastic body includes a first elastic member provided in a gap between an outer peripheral portion of the first main surface of the metal porous membrane and the housing, an outer peripheral portion of the second main surface of the metal porous membrane, and the housing. The filtration filter device of Claim 1 comprised by the 2nd elastic member provided in the clearance gap between.   The filtration filter device according to claim 2, wherein the first elastic member and the second elastic member are thicker than the metal porous membrane.   The filtration filter device according to claim 2 or 3, wherein the first elastic member and the second elastic member are the same member.   The filtration filter device according to claim 2, wherein the first elastic member is thicker than the second elastic member.   The said 1st elastic member is a cyclic | annular member, and is formed in the taper shape so that an opening area may become large as an internal peripheral surface leaves | separates from the 1st main surface of the said metal porous film. The filtration filter device according to any one of the above.   The said 2nd elastic member is a cyclic | annular member, and is formed in the taper shape so that an opening area may become large as an internal peripheral surface leaves | separates from the 2nd main surface of the said metal porous film. The filtration filter device according to any one of the above.   The said 1st elastic member and the said 2nd elastic member are formed so that each external shape may be larger than the external shape of the said metallic porous membrane, and it is mutually contacting on the outer side of the said metallic porous membrane. The filtration filter device according to any one of the above.   The filtration filter device according to any one of claims 2 to 8, wherein the first elastic member has a flat surface and is in surface contact with the outer peripheral portion of the first main surface of the metal porous membrane. .   The filtration filter device according to any one of claims 2 to 9, wherein the second elastic member has a flat surface, and is in surface contact with the outer peripheral portion of the second main surface of the metal porous membrane on the flat surface. .   The filtration filter device according to claim 1, wherein the elastic body includes a first elastic member provided in a gap between an outer peripheral portion of the first main surface of the metal porous membrane and the housing.   The filtration filter device according to any one of claims 1 to 11, wherein the elastic body is made of a resin material or a rubber material.   The housing includes at least two members, a first housing part provided with the fluid inflow passage and a second housing part provided with the fluid discharge passage, and the first housing part and the second housing part, The filtration filter device according to claim 1, which is configured to be detachable from each other.   14. The filtration filter device according to claim 13, wherein a distance between a surface of the first housing portion and a surface of the second housing portion facing each other with the metal porous membrane interposed therebetween is adjustable.

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