JP2013129654A - Tablet containing citric acid and sodium bicarbonate, method for producing the same, cosmetic material containing high concentration bicarbonate ion, and cosmetic method using the cosmetic material - Google Patents

Abstract

[PROBLEMS] The present invention pays attention to the useful effects of hydrogen ions or bicarbonate ions generated when a tablet, which is a mixture of citric acid and sodium bicarbonate, in water, on the living body, and contributes greatly to maintaining the homeostasis of the internal environment of the living body. Provided is a tablet containing citric acid and sodium bicarbonate.
The tablet containing citric acid / bicarbonate of the present invention is in the form of a tablet containing citric acid, sodium bicarbonate as a main component, and a binder, dispersant, lubricant, fluidizing agent, etc. such as PEG, By absorbing the hydrogen ions and bicarbonate ions generated when the tablets are in water into the body fluid in the living body, the acid-base equilibrium of the body fluid is achieved, and the structure is made to contribute to maintaining the homeostasis of the living body internal environment.
[Selection] Figure 1

Description

  The present invention pays attention to the useful effects on the living body of hydrogen ions and bicarbonate ions generated when a tablet, which is a mixture of citric acid and sodium bicarbonate, in water, and can greatly contribute to maintaining the homeostasis of the internal environment of the living body. The present invention relates to a tablet containing citric acid / bicarbonate and a method for producing the same, a cosmetic material containing a high concentration of bicarbonate ions, and a cosmetic method using the cosmetic material.

  Conventionally, a mixture containing carbonate or bicarbonate and an organic acid is molded by tableting or the like, and used as a bath preparation, a facial cleanser, or a bactericidal agent in tablet form, has been commercialized and put into practical use.

  As this type of tablet, Patent Document 1 discloses that a granulator is used and a mixture obtained by heating and cooling a mixture of citric acid and polyethylene glycol is heated, as well as a mixture of sodium bicarbonate and polyethylene glycol. A tablet obtained by mixing and compressing a granulated product obtained by cooling at a predetermined ratio has been proposed.

  However, in the case of the tablet of Patent Document 1, the focus is on the solubility of a mixture of citric acid and sodium bicarbonate in water, and hydrogen ions and bicarbonate generated when the mixture of citric acid and sodium bicarbonate is in water. It does not focus on useful effects of ions on living bodies.

Further, in the past, carbonic acid cosmetic products that generate not only CO ₂ but also HCO ₃ ⁻ (bicarbonate anion) have not been developed yet.

JP 2011-105615 A

The problem to be solved by the present invention is to maintain the homeostasis of the internal environment of the living body by paying attention to the useful effect on the living body of hydrogen ions and bicarbonate ions generated when the tablet, which is a mixture of citric acid and sodium bicarbonate, is dissolved in water. There are no tablets containing citric acid and baking soda that can greatly contribute to the above, and carbonated cosmetic products that generate HCO ₃ ⁻ (bicarbonate anion) as well as CO ₂ have not been developed yet. It is.

  The tablet containing citric acid / bicarbonate of the present invention is in the form of a tablet containing citric acid, sodium bicarbonate as a main component and containing a binder, a dispersant, a lubricant, a fluidizing agent, etc. such as PEG. The main feature is that hydrogen ions and bicarbonate ions that are sometimes generated are absorbed into body fluids in the body to achieve acid-base balance of the body fluids and contribute to maintaining the homeostasis of the body's internal environment.

  According to the invention of claim 1, it is a tablet form with good handleability, and by absorbing the hydrogen ions and bicarbonate ions generated when the tablet is in water into the body fluid in the body, the acid-base balance of the body fluid is achieved, It is possible to realize and provide a tablet containing citric acid and baking soda that exhibits a useful effect of contributing to maintaining the homeostasis of the internal environment of the living body.

  According to invention of Claim 2, it is a tablet form with favorable handleability, The body fluid by making the biological body fluid absorb the hydrogen ion and bicarbonate ion which generate | occur | produce at the time of water-solution in bathing of a tablet, face washing, hair washing, etc. A tablet containing citric acid and baking soda that demonstrates useful effects of acid-base balance, contributing to cell activation in the living body, contributing to metabolism promotion, and maintaining homeostasis of the internal environment by participating in the citric acid cycle Can be realized and provided.

  According to the invention of claim 3, in the form of a tablet having good handleability, a long-term supply action of hydrogen ions and bicarbonate ions generated when the tablet is dissolved in water, pharmaceuticals, supplements, cosmetics, foods, drinks It is possible to realize and provide a tablet containing citric acid and sodium bicarbonate that exhibits a useful effect of being able to exert a synergistic effect with these by mixing with water or the like.

  According to invention of Claim 4, it is a tablet form with favorable handleability, The bicarbonate ion produced from the tablet containing a citric acid and sodium bicarbonate is absorbed in a local part by continuing to apply this tablet to the local part of a biological body. Thus, it is possible to realize and provide a tablet containing citric acid and sodium bicarbonate that exhibits the useful effect of being able to contribute to the maintenance of homeostasis in the in vivo local environment.

  According to the invention described in claim 5, by utilizing the softening action of the skin surface by sodium citrate generated by the reaction of sodium ion and citric acid that slowly dissolves when this tablet is dissolved in hot water during bathing or the like, Realize and provide tablets containing citric acid and baking soda that can absorb hydrogen ions and bicarbonate ions that dissolve into the skin and contribute to maintaining the homeostasis of the internal environment. Can do.

  According to the invention of claim 6, in the form of a tablet having good handleability, the remaining hot water containing hydrogen ions and bicarbonate ions generated when the tablets are bathed, washed, washed with water, etc. when water is added is supplemented with washing water. It is possible to realize and provide a tablet containing citric acid and sodium bicarbonate that exhibits a useful effect that it can be used as a growth auxiliary water for plants such as water, plants, and vegetables.

  According to invention of Claim 7, it is a tablet form with favorable handleability, The hydrogen ion water which does not contain the impurity which generate | occur | produces at the time of the water solution of this tablet is used as washing auxiliary water of various articles | goods, and combustion auxiliary water of fossil fuel A tablet containing citric acid and baking soda that can be used and exhibits a useful effect in combination with other types of articles can be realized and provided.

  According to invention of Claim 8, it is a tablet form with favorable handleability, and raises the density | concentration of the carbon dioxide gas generated at the time of water solubility of this tablet by making it water-soluble with the tablet of pH 5-6.5 as an adjuvant. It is possible to realize and provide a tablet containing citric acid and baking soda that can exert a blood flow promoting effect by vascular dilation in a living body.

  According to the ninth aspect of the present invention, the weight ratio of citric acid: baking soda is 1: 3-6, the pH can be adjusted in tablet form, and the amount of bicarbonate ions generated can be adjusted. To 8 can realize and provide a tablet containing citric acid and baking soda capable of exhibiting the effects of the invention described in any one of.

  According to the invention of claim 10, based on a constitution in which the anhydrous citric acid powder and the baking soda powder are the main components, and a binder, a dispersant, and a lubricant such as PEG are mixed and tableted as an auxiliary agent, It is possible to realize and provide a production method capable of easily producing a tablet containing citric acid and sodium bicarbonate that exhibits the effects of each invention and has good handleability.

  According to the eleventh aspect of the invention, polyethylene glycol 6000 is added to a raw material in which anhydrous citric acid, a lubricant and a part of silicic anhydride as a fluidizing agent are added and mixed to improve fluidity, and sodium bicarbonate is mixed. A small amount of lubricant, sucrose fatty acid ester, a solubilizing agent and a binder, PVP, are added and tableted to produce a group based on the effects of each of the above inventions and good handleability. The manufacturing method which can manufacture easily the tablet containing a certain citric acid and baking soda can be implement | achieved, and can be provided.

  According to the twelfth aspect of the invention, in the invention of the eleventh aspect, the handleability in which the bicarbonate ion generation amount is adjusted by adjusting the pH by adjusting the weight ratio of anhydrous citric acid: baking soda to 1: 3-6. It is possible to realize and provide a production method capable of easily producing a tablet containing citric acid / soda soda having good quality.

According to the invention of claim 13, a face impregnated with a first cosmetic material comprising a gel containing citric acid as a main component and a fragrance comprising a small amount of peppermint, olive oil and the like, and a high concentration of HCO ₃ ⁻ With the configuration including the second cosmetic material made of a mask, both CO ₂ and HCO ₃ ⁻ can be generated at a high concentration at the same time, giving the user a sufficient feeling of use and satisfaction. A cosmetic material containing a high concentration of bicarbonate ions can be realized and provided.

According to invention of Claim 14, apply | coat the 1st cosmetics which consist of a gel which has citric acid as a main component and added the fragrance | flavor which consists of a small amount of peppermint, olive oil, etc. to a face, and it is left as it is for 1-3 minutes. A second cosmetic material comprising a step and a face mask impregnated with high concentration HCO ₃ ⁻ is applied to the face to generate a large amount of air bubbles and a high concentration due to gentle attenuation of the air bubbles over time. By performing the step of generating HCO ₃ ⁻ and promoting the cosmetic effect of the face, both CO ₂ and HCO ₃ ⁻ can be generated simultaneously in a high concentration state. It is possible to realize and provide a cosmetic method using a cosmetic material containing a high concentration of bicarbonate ions that can be used and enjoyed.

FIG. 1 is a diagram showing a formulation example of a pH 6.5 type tablet in an example of the present invention. The figure shows an example of blending pH 7.5 type tablets in this example. The figure shows the contents of the concentration stability test based on JISK0101 in this example and the analysis results of pH 6.5 type tablets up to 24 hours of pH, hydrogen ion, total carbonate (hydrogen carbonate ion, carbonate ion, free carbonate). FIG. FIG. 4 shows the pH of the tablet of type 7.5 in the concentration stability test based on JISK0101 in this example, hydrogen ions, and total carbonate (hydrogen carbonate ion, carbonate ion, free carbonate) up to 24 hours. It is a figure which shows the analysis result at the time of adding a citric acid to the analysis result of and pH7.5 type tablet. FIG. 5 is a diagram showing the contents and analysis results of the baking soda and citric acid test of the pH 6.5 type tablet and the contents and analysis results of the baking soda and fumaric acid test of the pH 6.5 type tablet in this example. FIG. 6 is a schematic view showing a second cosmetic material in a cosmetic material containing a high concentration of bicarbonate ion according to another embodiment of the present invention. FIG. 7 is a flowchart showing processing steps of a cosmetic method using a cosmetic material containing a high concentration of bicarbonate ions according to another embodiment of the present invention. FIG. 8 is a diagram showing the results of the pH, total carbonate, bicarbonate ion, carbonate ion, and free carbonate concentration stability tests on tablets (1 tablet) containing citric acid / bicarbonate according to this example. FIG. 9 is a graph showing the analysis results of the pH, total carbonate, bicarbonate ion, carbonate ion, and free carbonate concentration stability tests on tablets (1 tablet) containing citric acid / bicarbonate according to this example.

  The present invention pays attention to the useful effects on the living body of hydrogen ions and bicarbonate ions generated when a tablet, which is a mixture of citric acid and sodium bicarbonate, in water, and can greatly contribute to maintaining the homeostasis of the internal environment of the living body. Achieving and providing tablets containing citric acid and baking soda that can be easily handled and provided with the main component of citric acid and baking soda, binders, dispersants, lubricants, and fluids such as PEG In the form of a tablet containing an agent, etc., the body fluid is acid-base balanced by absorbing the hydrogen ions and bicarbonate ions generated when the tablet is bathed, washed, washed with water, etc. into the body fluid. It was realized by a structure that contributes to maintaining the homeostasis of the internal environment by activating, contributing to the promotion of metabolism, and contributing to the citric acid cycle.

Hereinafter, a tablet (citric acid tab) containing citric acid and sodium bicarbonate according to an embodiment of the present invention and a production method thereof will be described in detail.
A tablet (citric acid tab) 1 containing citric acid / bicarbonate of this example is formed to have a diameter of 50 mm and a weight of 40 g, for example.

  Tablets containing citric acid and baking soda according to the present example are citric acid powder, sodium bicarbonate powder compressed using PEG (polyethylene glycol) and anhydrous, and tableted. As an example of the weight ratio, Examples include sodium bicarbonate (sodium bicarbonate) 65% by weight, citric acid 30% by weight, and PEG 5% by weight. In addition to tablets, it is of course possible to use gels or capsules.

  An example of the actual weight of the tablet containing citric acid / bicarbonate is 40 g in total, 25.5 g of sodium bicarbonate, 11.7 g of citric acid, 2.8 g of PEG and others.

  Next, the function that the tablet containing citric acid and sodium bicarbonate according to the present example exerts and the theoretical background of the utility will be described.

  In general, the living body (human) is composed of approximately 60 trillion cells, and each cell floats in a body fluid (60% of body weight), performs a unified and harmonious function, and has an independent personality. It is known to function as a life form.

  Plants use the energy of the sun directly by the action of chlorophyll to fix various earth elements based on carbon dioxide and water, and produce various nutrients, but animals do not have that ability, just It is a living thing that borrows nutrients and oxygen produced by plants, ingests and burns them, indirectly bathes in the blessings of the sun. Moreover, the living body evolves and continues to live even by eating and nourishing other animals.

  Cells that make living organisms cannot directly use solar energy, but they take oxygen in the air through the lungs, pass it to hemoglobin in red blood cells, and are carried to the cell population (tissue) by blood (part of body fluid). The cells take in the oxygen, burn the nutrients, take out the energy (biological energy), and fix it as a high energy substance called ATP.

  This gas exchange between the cells and blood is called tissue respiration (internal respiration) in contrast to gas exchange in the lung (lung respiration = external respiration).

  Intracellular organelles similar to this intracellular power plant (substation) are membrane structures comparable to the chloroplasts of plants called mitochondria.

  Every function of the cell is carried out using the energy (ATP) produced here.

  In mitochondria, which can be compared to cell power plants, nutrients (mainly glucose and fatty acids) carried by body fluids (mainly blood) are burned using oxygen that is also carried by red blood cells (mainly Hb), and high-energy substances ATP, which is a mass of biological energy, is created.

  This mechanism is catalyzed by a chain of enzymes in mitochondria, which promotes intracellular metabolism of degradation and synthesis.

  This group of enzymes is called cytochrome-based enzymes (iron-containing enzymes, but there are other elements in the body, such as muscle lean elements: myoglobin, hemoglobin in red blood cells, etc.).

  Substances that support the action of this enzyme are called coenzymes, and there are vitamin B group and coenzyme Q.

  The mechanism of energy production in the mitochondria catalyzed by the enzyme group of the cytochrome system is called the TCA cycle (citrate cycle + carbonate cycle).

  Therefore, mitochondria are the source of human vitality.

  The cells that make up the body of the living body use the energy aggregated in this ATP to make other organelles [lysosome, rough surface (smooth surface) endoplasmic reticulum, Golgi body, lysosome and nucleus (RNA / DNA) Etc.] to create substances necessary for life (structural proteins, functional proteins, immune substances, etc.) and maintain life.

  It should be noted that citric acid and carbonic acid are greatly related to the TCA cycle, and the effects of tablets containing citric acid and baking soda include biological metabolism up, metabolism promotion, stress relaxation, fatigue recovery, Although energy metabolism increase etc. are mentioned, it is thought that in addition to this, the invisible involvement in the TCA cycle contributes.

  Next, baking soda is thought to play a role in the regulation of the internal environment in which cells live (internal environmental homeostasis), and is greatly involved in the aging of living organisms.

That is, sodium bicarbonate becomes weak alkaline bicarbonate ion (HCO ₃ ⁻ ) when dissolved in water.

When this HCO ₃ ⁻ is absorbed from the skin of the living body and enters the blood through the capillaries, the acid-base balance of the body fluid is moderately adjusted and greatly contributes to the homeostasis of the cell internal environment.
The optimum pH for the cells to live is in the weak alkaline region of 7.35-7.45.

Various factors (endocrine, autonomic nerves, brain (especially hypothalamus), cell metabolism, respiratory organs, digestive organs [especially gastrointestinal, liver, pancreas], kidneys [especially tubules]) is related, arterial CO ₂ saturation and HCO ₃ ^- concentration of decisive element.

  Abruptly changing the acid-base balance of a body fluid causes a tremendous tremor in the internal environment, which is not recommended, but it is thought that it is good to absorb it from the skin and adjust the internal environment softly. .

  In particular, the tablet containing citric acid and sodium bicarbonate according to the present example, which is mainly composed of citric acid and sodium bicarbonate, has the advantage of being dissolved in hot water and supplying hydrogen ions and bicarbonate ions over a relatively long period of time.

Furthermore, the sodium ions left on the skin surface meet weakly acidic citric acid and become sodium citrate, which changes into a weakly alkaline vegetable soap on the skin surface, softens the cuticle layer of the skin, and bicarbonate ions It is thought that it is easy to pass through the skin.
Moreover, the reaction formula regarding the hydrogen carbonate, hydrogen ion, bicarbonate ion, water, and carbon dioxide gas in the tablet containing citric acid and sodium bicarbonate according to this example is shown as the following (Chemical Formula 1).

(Characteristic)
Next, the characteristic of the tablet containing a citric acid and sodium bicarbonate concerning a present Example is demonstrated in detail.

  In general, baking soda can be easily solidified (tablets), but citric acid is difficult to solidify because it reacts immediately even with very little water.

Even when sodium bicarbonate and citric acid are put in water, H ₂ CO ₃ shown in (Chemical Formula 1) shifts to H ₂ CO ₂ at a stretch, so the essential high concentration and high quality ions (H ⁺ , HCO ₃ ⁻ ) Does not occur.

The tablet containing citric acid / sodium bicarbonate in this example is 40 g in total, 25.5 g of sodium bicarbonate, 11.7 g of citric acid, and PEG 2.8 g in a weight ratio of 1 tablet to 1 g / l. Thus, a high concentration of HCO ₃ ⁻ of about 8,000 to 10,000 ppm is generated, and the concentration is maintained for a long time as shown in FIG.

  Hereinafter, the effect of the tablet containing citric acid and sodium bicarbonate according to this example will be described.

In the case of bathing (full body bath, half body bath, foot bath, etc.), HCO ₃ ⁻ generated from tablets containing citric acid and sodium bicarbonate in a hot water bath as a bath agent passes through the epidermis of the living body (percutaneous absorption) and passes through the dermis. Absorbed by capillaries, it controls the internal environment, adjusts acid-base balance, and exerts a bathing effect that greatly contributes to maintaining the homeostasis that supports the life of the body (maintaining the microenvironment in which cells live). .

Further, HCO ₃ ⁻ is expected to be involved in bioenergy (ATP: adenosine triphosphate), and recovers muscle fatigue throughout the body.

Living environment is disturbed due to air pollution, water pollution, food pollution, etc., and negative ions tend to be insufficient in daily life. According to the tablet containing citric acid and baking soda in this example, generation of extremely high quality HCO ₃ ⁻ Thus, the internal environment of the living body cell can be corrected.

  In the case of the tablet containing citric acid and baking soda of this example, the blood vessel is expanded by the effect of the generated carbon dioxide gas to increase the strength of the blood vessel and to exert the blood flow promoting effect.

  Furthermore, the tablet containing citric acid and baking soda according to the present example is particularly effective in improving the cold symptoms of anticancer drug patients and women (approximately 70% of women are cold).

  It is also possible to create a dedicated foot bath that can be inserted into the calf and put a bath containing hot water and a tablet containing citric acid and baking soda into the foot bath.

The tablets containing citric acid and sodium bicarbonate used as the above bathing agent are not merely bathing agents, but high concentrations (1 tablet / liter, 8000 ppm) of HCO ₃ ⁻ are produced. Therefore, this HCO ₃ ⁻ is the basis of energy. Since it is involved in mitochondria (60 trillion x 1000 = 6kyo), it functions as a mitochondrial function promoter, becomes the basis of immunomedicine and immunocosmetics, and greatly contributes to the maintenance of biological homeostasis.

In addition, citric acid in a tablet containing citric acid and sodium bicarbonate according to the present example generates sodium citrate by combining sodium ions and citric acid when water is dissolved, softens the epidermis (cuticle layer), HCO ₃ ⁻ It has the effect of facilitating passage.

  Furthermore, the use of a tablet containing citric acid and sodium bicarbonate according to the present example is utilized for reduction of pulse and diastolic blood pressure, improvement of veins and lymph, and the like.

As the carbonated spring in Japan Pharmacopoeia, CO ₂ it is known those 1000ppm concentrations and as the population carbonated spring device, high-pressure carbon dioxide cylinder adopts the hollow element film usage Mitsubishi Rayon Co. Is known, but there is a risk of breaking the bath due to strong acid (pH 3.5), which is not very popular at home.
In the case of the tablet containing citric acid and sodium bicarbonate in the present example, it is difficult to secure high concentrations of HCO ₃ ⁻ and CO ₂ with a single tablet.
Although the concentration of HCO ₃ ⁻ has already been secured, the CO ₂ concentration is low and attenuates in a short time.
In order to complement this point, for example, it is preferable to optionally use a tablet having a pH concentration of 5 to 6 as an auxiliary agent to increase the CO ₂ concentration. For example, an auxiliary agent that conforms to 1,000 ppm / 1 L of CO ₂ recognized by the Japanese Pharmacopoeia is added.
The effect of CO _{2 has} an effect of promoting blood flow by vasodilation and the like, which is extremely preferable for users. Further, if the concentration of CO ₂ is increased, it is recommended as a carbonated spring recognized by the Japanese Pharmacopoeia.

The tablets containing citric acid and baking soda according to this example can be used for specific applications as shown below due to H ⁺ and HCO ₃ ^{− that} are generated for a long time by mixing with moisture, and each can expect a synergistic effect.
(1) Cosmetics Face washing, hair washing, treatment (2) Fragrance, deodorant (3) Humidifier, air purifier (4) Disinfectant (non-alcohol) spray type, liquid type (5) Transdermal absorption type analgesia Agent, anti-photosis agent (toothpaste, eye drops, nasal drops, other chemicals)
(6) Face pack (7) Cleaning agent, wiping cloth (8) Gauze (9) Synergistic effect by blending with pharmaceuticals, supplements and drinking water (10) Dirty removal (indoor cleaning tools, high-quality products, dentition cleaning) etc)
(11) Liquors (beer, sake, wine, etc.)
(12) Laser equipment cleaning

  The specific utilization of the tablet containing citric acid and baking soda according to this example and the effect thereof will be described with further examples.

(1) Local improvement Put a tablet containing citric acid and baking soda in a container with a capacity of about 10 cc (for example, in the shape of water glasses) that fits in the palm of both hands, and press it against any local part of the living body slightly, for example, about 15 minutes. For example, press against the lumbar region (back of the kidney).

  As a result, bubbles are filled between both palms and the lumbar region, and high-concentration bicarbonate ions penetrate the skin and exert an effect of improving the function of the kidneys and liver.

  Similar effects can be expected for other local areas. Furthermore, for example, a similar effect can be expected by creating a bra-type exclusive tool and holding the tablet containing citric acid / bicarbonate with the dedicated tool and applying it to the local area.

(2) Makeup effect / Fashion effect For example, 1 liter of water is put in a basin, and one tablet containing citric acid / bicarbonate is put in and breathed in (for example, 3 times).

  This reduces stains and wrinkles and exhibits a makeup effect and a facial effect. Furthermore, it contributes to the improvement of legal lines.

  Also, put 1 liter of water into the basin, put one tablet containing citric acid / bicarbonate, soak your face in the water in the basin and open your eyes. This can be expected to clean the eyes.

(3) Manufacture of multifunctional water Make multifunctional water by putting one tablet containing citric acid and baking soda in 2 liters of water (four 500cc plastic bottles).

  These are used as facial cleansing water, facial cleansing treatment liquid (for improving sweat odor and aging odor), face pack, and tooth cleaning liquid (for improving stain, bad breath and denture odor). In this case, there is a remarkable effect that the user himself / herself can simply hand-made beauty water that is suitable for the user.

In addition, the high-concentration ions (H ⁺ , HCO ₃ ⁻ ) can be used for health drinking water when sodium bicarbonate or citric acid, which is a tablet material containing citric acid / bicarbonate, is produced using natural materials. Is preferred. In this case, it is necessary to note that baking soda contains Na ⁺ and is not preferable for blood-disordered people.

  On the other hand, in a use mode in which a tablet containing citric acid / bicarbonate is dissolved in water and absorbed from the skin surface, sodium citrate is produced by the combination of sodium ions and citric acid when dissolved in water.

This sodium citrate plays the role of a weakly alkaline (pH 7.2) vegetable soap on the skin surface, softens the epidermis (cuticle layer), facilitates passage through HCO ₃ ⁻ , and is more easily inhaled into capillaries, Contributes to cell activation.

(4) Foot bath and wiping Used to improve sick odor, elderly odor, aging odor, etc., and to prevent and improve bedsores.

(5) Use as a dedicated shower head.

(6) Deodorization of specific odors and aging odors Both baking soda and citric acid have a deodorizing effect (synergistic effect).

(7) Cross-coupling effect The tablet containing citric acid and sodium bicarbonate according to this example is obtained by solidifying sodium bicarbonate and citric acid in anhydrous and high pressure, and realizes simultaneous treatment with alkali and oxidation. Therefore, a kind of cross coupling effect can be expected.

(8) Dissolve the tablet containing citric acid / bicarbonate according to this example in hot water or water and use it for bathing, face washing, hair washing, etc., and then generate the remaining hot water or water containing hydrogen ions and bicarbonate ions. It can also be used as auxiliary water for washing water, water for plant growth such as plants and vegetables, and water for repelling pests.

(9) Since the generated ions (H ⁺ , HCO ₃ ⁻ ) are released into the room together with the steam by putting the tablet containing citric acid / bicarbonate according to the present embodiment into the humidifier, the room is air-cleaned. Contribute to Moreover, by putting the tablets containing citric acid and baking soda according to this embodiment into a spray container containing water and spraying, it is possible to expect air purification of the room and the disinfection effect of the entrance space.

(10) Utilizing hydrogen ion water that does not contain impurities generated when a tablet containing citric acid / bicarbonate according to the present embodiment is dissolved in water as washing auxiliary water for various articles, combustion auxiliary water for fossil fuels, etc. it can. When used as combustion auxiliary water, it contributes to fuel efficiency savings (14% gasoline, 22.4% hybrid, 42% electric vehicles) and CO ₂ reduction.

(11) The tablet containing citric acid / bicarbonate of this example is
a. Since the main components of the product are sodium bicarbonate and citric acid, both have antibacterial and anti-odor effects.
b. CO ₂ and HCO ₃ ⁻ are generated at the same time. Particularly, HCO ₃ ⁻ has a surprisingly high concentration (60 g, 1 L, 39,000 ppm), and is retained for a long time. FIG. 8 shows an analysis result table of the concentration stability test of pH, total carbonic acid, bicarbonate ion, carbonate ion, and free carbonic acid for a tablet (1 tablet) containing citric acid / bicarbonate according to this example. Is shown in FIG. In the tablet containing citric acid and sodium bicarbonate according to this example, as shown in FIGS. 8 and 9, high concentration of HCO ₃ ⁻ is generated, and the concentration is maintained for a long time as long as there is moisture.
c. HCO ₃ ⁻ activates mitochondria, maintains “biological homeostasis”, and greatly contributes to healthy longevity and beauty.

The main uses of the tablet containing citric acid / bicarbonate of this example are as follows.
1. Spa resort (large: 1 tablet 60g)
Bathtub for 10 tons: As a replacement of bath water every 5 days, 30 tablets for the first time, 20 tablets for the second day to 10 tablets each for 5 days, a total of 80 tablets (supplemented because HCO ₃ ⁻ is absorbed into the human body by bathing) By using this, you can enjoy the hot spring feelings of Japanese luxury brands, and because HCO ₃ ⁻ has a tremendously high concentration, you can recover your health and beauty.

  2. Since the tablet containing citric acid and sodium bicarbonate of this example is extremely excellent in skin absorption, it can collaborate with the aroma effect of Chinese herbal medicine to the maximum, and is very suitable for footbath.

  3. Ideal for head spas and suitable for female hair washing in beauty salons and beauty salons. Women's perm and color liquids have many hair-damaging ingredients, so any shampoo is hard to fall off, but using these tablets gently wash away, gently correct damaged hair, and keep the hair shiny and firm. . In addition, toxins in the body are excreted in the scalp, which is also cleaned cleanly to restore and maintain the ideal skin.

The tablets containing citric acid and baking soda in this example generate HCO ₃ ⁻ with extremely high concentration, high quality, and long-lasting concentration. Therefore, various tablets can be used depending on the combination with other products. It can be expected to be used in various fields.

Hereinafter, the synergistic effect by the combination with other products will be described.
(1) Strengthening immunity acquired Acquired polysaccharides such as glucosamine, chondroitin, collagen, and hyaluronsan are disadvantageous in that their products are expensive and have superiority, but are difficult to absorb through the skin or in the body. There is.

The combined use with the tablet containing citric acid / bicarbonate of this example can be expected to increase the absorption action of the starch-free polysaccharide, which greatly contributes to the original characteristics of the powder-free polysaccharide itself.
In addition, a synergistic effect can be expected when used in combination with products that are difficult to be transdermally or absorbed into the body.

(2) high concentrations of HCO ₃ ^- utilization by the product and the combined use effect high concentration of HCO ₃ ^- and footbath effect tablets uses, including citric acid sodium bicarbonate which generates, the disease modifying effect of wiping of the product solution using I can expect.

(3) Mitochondrial activity effect of high concentration of HCO ₃ ⁻ (a) Macrophage Macrophages are promoted based on the mitochondrial activity effect of HCO ₃ ⁻ . Macrophages are a type of white blood cell that is an amoeba-like cell that forms part of the immune system, and that phagocytoses and digests bacteria, viruses, or dead cells that have invaded the body. Large lymphocytes, small lymphocytes).

(B) Cancer cells are predominantly aerobic glycolysis, but high concentrations of HCO ₃ ⁻ have the effect of returning to the mitochondrial system (increased body temperature).

(C) Mitochondria produce energy essential for health, but when it is of poor quality, it produces active enzymes. Good quality HCO ₃ ⁻ by using the tablet containing citric acid / bicarbonate of this example exhibits the effect of eliminating the active enzyme.

  (D) ATP (mitochondria) conversion efficiency of energy metabolism can be expected to be 45%.

(E) Prevention of free radicals Due to the high concentration of HCO ₃ ⁻ generated by the tablets containing citric acid and sodium bicarbonate according to this example, an improvement effect on active enzyme malfunction and oxidative damage can be expected.

(F) Apoptotic effect By the action of high concentration of HCO ₃ ⁻ generated in the tablet containing citric acid / bicarbonate of the present Example, the function of mitochondria is promoted and the cell cleaning function by controlling apoptosis can be expected.

  Next, the manufacturing method of the tablet (single weight 40g, flat tablet of diameter 50mm) containing the citric acid and sodium bicarbonate of a present Example is demonstrated with reference to FIG. 1, FIG.

  The method for producing a tablet containing citric acid and sodium bicarbonate of this example was prepared by adding a part of anhydrous citric acid and a part of silicic acid which is a lubricant and a fluidizing agent to improve fluidity and to make a raw material A. Then, a fragrance is mixed with the remainder of silicic acid to prepare a raw material B, and PEG (polyethylene glycol) 6000 is mixed with a small amount of lubricant, sucrose fatty acid ester, a solubilizer and a binder, PVP. The raw material C is prepared by uniformly mixing the raw material A, the raw material B, and the raw material C, and then tableting them.

  The blending table of each raw material in this case is shown in FIGS. FIG. 1 shows a formulation example of a pH 6.5 type tablet, and FIG. 2 shows a formulation example of a pH 7.5 type tablet.

  Next, FIG. 3 to FIG. 5 show the concentration stability test and its analysis results, tablets, citric acid test and analysis results thereof, baking soda and fumaric acid test and analysis results thereof regarding tablets containing citric acid and baking soda of this Example. The description will be given with reference.

  FIG. 3 shows the contents of the concentration stability test based on JISK0101, and the results of analysis of pH 6.5 type tablet pH, hydrogen ion, total carbonate (hydrogen carbonate ion, carbonate ion, free carbonate) up to 24 hours. Is.

  As is apparent from the analysis results shown in FIG. 3, the tablet (pH 6.5 type) containing citric acid and sodium bicarbonate of this example has a long bicarbonate ion of 10400 (mg / L) even after 24 hours. It was found that the time concentration continued.

  Further, as apparent from the analysis result shown in the upper column of FIG. 4, the tablet of this example containing citric acid / bicarbonate (pH 7.5 type) had 25200 mg / kg of bicarbonate ions even after 24 hours. L) and it became clear that the concentration continued for a long time.

  Furthermore, as the analysis result shown in the lower column of FIG. 4 shows, it was also clarified that when citric acid was further added to a pH 7.5 type tablet, hydrogen carbonate ions were greatly reduced.

  The upper column in FIG. 5 shows the baking soda, citric acid test and analysis results of pH 6.5 type tablets. In this case, the bicarbonate ion is in the range of 0 to 24 hours, the bicarbonate ion is It was 4840-5650 (mg / L).

  The lower column of FIG. 5 shows the baking soda, fumaric acid test and analysis results of pH 6.5 type tablets. In this case, the bicarbonate ions range from 0 to 24 hours. It was 4659-5540 (mg / L).

  As described above, it was found that the tablet of the present example did not generate carbon dioxide gas upon storage, and the solubility of the tablet was very good when used.

  The tablet containing citric acid / bicarbonate according to the present invention has been found to have a great improvement effect on rheumatism, Parkinson's disease, coldness, hypertension and the like by questionnaire surveys for many users.

  Next, a cosmetic material containing high-concentration bicarbonate ions according to another embodiment of the present invention and a cosmetic method using the cosmetic material will be described with reference to FIGS.

A cosmetic material containing a high concentration of bicarbonate ion according to another embodiment of the present invention is a gel (PH 5.5 to 6.5) containing citric acid as a main component and a small amount of a fragrance (for example, mint or olive oil). And a second mask comprising a face mask impregnated with high-concentration HCO ₃ ⁻ (PH 7.5 to 8.5) having the characteristics described above as shown in FIG. The cosmetic material 1 is included.

(Beauty method)
Next, with reference to FIG. 7, a cosmetic method using the cosmetic material described above will be described.

  First, the first cosmetic material is applied to the face and left for 1 to 3 minutes.

  Next, after the elapse of 1 to 3 minutes, the second cosmetic material is applied to the face and waits for 30 to 50 minutes.

As a result, a large amount of air bubbles (CO ₂ ) are generated at the same time when the second cosmetic material is applied to the face, and the user can obtain a sufficient feeling of use and satisfaction. Thereafter, the air bubbles are gently attenuated. As a beauty effect, the highly concentrated HCO ₃ ⁻ is generated as a beauty effect, and a remarkable beauty effect that has never existed before can be obtained.

In the past, carbonated beauty products are rapidly gaining popularity as a new item that is expected to have a beautiful beauty effect. However, even if it is a spray type (circulator), facial cleansing mask powder, or face pack, only CO _{2 is} available. It does not occur and can only expect the carbonation effect.

That is, a carbonated beauty product that generates not only CO ₂ but also HCO ₃ ⁻ (bicarbonate anion) has not been developed yet.

Face masks impregnated with carbonated spring tablet ingredients are said to have a great effect on beauty, but the amount of CO ₂ generated is small, and even if there is a certain effect, face masks are applied to the face for beauty because of insufficient bubbles. The actual situation is that the user who puts it on cannot get a sufficient feeling of use and satisfaction.

It is also known that it is impossible to simultaneously generate both HCO ₃ ⁻ and CO _{2 in} a high concentration state.

On the other hand, according to the cosmetic material containing a high concentration of bicarbonate ions according to another embodiment of the present invention, by using the first cosmetic material and the second cosmetic material 1 together, Both CO ₂ and HCO ₃ ⁻ can be generated at a high concentration at the same time, and a sufficient feeling of use and satisfaction can be given to the user.

  In addition, according to the above-described beauty method using the cosmetic material, the user can obtain a sufficient feeling of use and satisfaction, and can enjoy a remarkable beauty effect that has not existed before.

  Tablets containing citric acid and baking soda according to the present invention are bath additives, facial cleansers, hair washes, treatments, cosmetics, fragrances, deodorants, disinfectants, wipes, wipes, and enhanced immunity. It can be applied to a wide variety of applications such as for mitochondrial activity.

  1 Second cosmetic agent

Claims (14)

  Citric acid and sodium bicarbonate as a main component, and a tablet form containing binders, dispersants, lubricants, fluidizing agents, etc., such as PEG. Hydrogen ions and bicarbonate ions generated when this tablet is dissolved in water A tablet containing citric acid and baking soda, which is absorbed into a body fluid to achieve acid-base balance of the body fluid and contribute to maintaining the homeostasis of the internal environment.   This is a tablet that contains citric acid and baking soda as the main components, and contains binders, dispersants, lubricants, fluidizing agents, etc. such as PEG. Hydrogen ions generated when the tablets are bathed, washed, washed with water, etc. Incorporates bicarbonate ions into body fluids to achieve acid-base balance in body fluids, contributes to cell activation of the body, contributes to metabolism promotion, and contributes to maintaining homeostasis of the body environment by participating in the citric acid cycle A tablet containing citric acid and baking soda.   Citric acid and sodium bicarbonate as the main component, and in the form of tablets containing binders, dispersants, lubricants, fluidizing agents, etc. such as PEG, hydrogen ions and bicarbonate ions generated for a long time when these tablets are water-soluble A tablet containing citric acid and baking soda using a supply action to exhibit a synergistic effect with pharmaceuticals, supplements, cosmetics, foods, drinking water, etc.   Citric acid, baking soda is the main ingredient, and it is in the form of a tablet containing binders, dispersants, lubricants, fluidizing agents, etc. such as PEG. A tablet containing citric acid and baking soda, characterized in that bicarbonate ions generated from a tablet containing succinic acid are absorbed locally and contribute to maintaining the homeostasis of the local environment in vivo.   Sodium tablets that contain citric acid and baking soda as the main components and contain binders, dispersants, lubricants, fluidizing agents, etc. such as PEG, and slowly dissolve when the tablets are dissolved in hot water during bathing. Utilizing the softening action of the skin surface by sodium citrate generated by the reaction between ions and citric acid, the hydrogen ions and bicarbonate ions that dissolve slowly are absorbed into the skin and contribute to maintaining the homeostasis of the internal environment. A tablet containing citric acid and baking soda.   This is a tablet that contains citric acid and baking soda as the main components, and contains binders, dispersants, lubricants, fluidizing agents, etc. such as PEG. Hydrogen ions generated when the tablets are bathed, washed, washed with water, etc. A tablet containing citric acid and baking soda, wherein the remaining hot water containing bicarbonate ions is used as supplementary water for washing water, planting, vegetable and other plants.   Citric acid, baking soda as the main component, and in the form of tablets containing binders, dispersants, lubricants, fluidizing agents, etc. such as PEG, hydrogen ion water that does not contain impurities generated when the tablets are water-soluble, A tablet containing citric acid and baking soda, which is used as washing auxiliary water for various articles and combustion auxiliary water for fossil fuels.   Citric acid and sodium bicarbonate as a main component, and a tablet form containing a binder such as PEG, a dispersing agent, a lubricant, and a fluidizing agent. The concentration of carbon dioxide generated when the tablet is water-soluble is adjusted to pH 5-6. A tablet containing citric acid and baking soda, which is enhanced by water-solubilizing the water-soluble agent or gel of .5 as an auxiliary agent and exerting a blood flow promoting effect due to vascular dilation of the living body.   The tablet containing citric acid / bicarbonate according to any one of claims 1 to 8, wherein the weight ratio of citric acid: bicarbonate is 1: 3-6.   A tablet containing citric acid and baking soda, characterized in that it is produced by mixing and tableting with anhydrous citric acid powder and baking soda powder as the main components, and mixing with PEG and other binders / dispersants / lubricants as adjuvants. Production method.   A part of silicic anhydride, a lubricant, and a part of silicic acid, which is a fluidizing agent, are mixed and mixed to improve fluidity. The raw material in which sodium bicarbonate is mixed is mixed with polyethylene glycol 6000 and a small amount of lubricant, sucrose fatty acid. A method for producing a tablet containing citric acid and sodium bicarbonate, comprising adding an ester, a solubilizing agent and PVP as a binder, and compressing the tablet.   The method for producing a tablet containing citric acid / bicarbonate according to claim 11, wherein the weight ratio of anhydrous citric acid: bicarbonate is 1: 3-6. A first cosmetic material comprising a gel containing citric acid as a main component and a fragrance comprising a small amount of peppermint, olive oil and the like;
A second cosmetic material comprising a face mask impregnated with a high concentration of HCO ₃ ⁻ ;
A cosmetic material containing a high concentration of bicarbonate ions, characterized in that Applying a first cosmetic material consisting of a gel containing citric acid as a main component and a fragrance made of a small amount of peppermint, olive oil or the like to the face and leaving it for 1 to 3 minutes;
A second cosmetic material composed of a face mask impregnated with high concentration HCO ₃ ⁻ is applied to the face to generate a large amount of bubbles, and the high concentration of HCO ₃ ⁻ due to gentle attenuation of the bubbles over time. Generating a cosmetic effect on the face,
A cosmetic method using a cosmetic material containing a high concentration of bicarbonate ions, characterized in that