JP2010090043A - Shampoo - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a shampoo excellently preventing the occurrence of itching of the scalp even when the amount of a formulated itching-inhibitor is little. <P>SOLUTION: The shampoo is obtained by formulating a surfactant, one or more kinds of the itching inhibitors (A) selected from the group consisting of glycyrrhizic acid and a glycyrrhizic acid salt, and one or more kinds the itching inhibitors (B) selected from the group consisting of 3-succinyloxyglycyrrhetic acid and a 3-succinyloxyglycyrrhetic acid salt. Preferably, the ratio (W<SB>2</SB>/W<SB>t</SB>) of the mass W<SB>2</SB>of the itching inhibitors (B) to the total mass W<SB>t</SB>of the mass W<SB>1</SB>of the itching inhibitors (A) and the mass W<SB>2</SB>of the itching inhibitors (B) is ≤0.45. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a shampoo, and more particularly to a shampoo that is excellent in suppressing the occurrence of itching in the scalp even when the amount of the itching inhibitor is small.

  Conventionally, surfactants have been incorporated into shampoos as cleaning ingredients, and in recent years, amino acid surfactants have been incorporated into shampoos because they have little irritation to the skin and eyes and can impart appropriate flexibility to hair. ing. However, although such advantages exist in amino acid surfactants, it may cause itching of the scalp after shampooing. Further, even when the hair is washed with a shampoo containing a surfactant other than an amino acid surfactant, it may cause itching of the scalp.

Therefore, in order to suppress itching, a compound having an anti-inflammatory action is considered. For example, as a shampoo containing the compound, in the example of Patent Document 1, acyl glutamic acid triethanolamine, which is an amino acid-based surfactant, and dipotassium glycyrrhizinate, which is a compound having an anti-inflammatory action, were added. A shampoo is disclosed. Patent Document 2 discloses a shampoo containing an anionic surfactant and dipotassium glycyrrhizinate or stearyl glycyrrhetinate.
JP 2000-327539 A JP 2007-254355 A

  However, since the techniques described in Patent Documents 1 and 2 contain a compound having an anti-inflammatory action, it is possible to suppress the occurrence of itchiness, but the price of a compound having an anti-inflammatory action among shampoo ingredients. Therefore, in order to reduce the raw material price of the shampoo after blending the compound, it is desired to provide a technology that is highly effective in suppressing stagnation even when the blending amount is small.

  Accordingly, an object of the present invention is to provide a shampoo that solves the above-mentioned problems in the prior art and is excellent in suppressing the occurrence of itching in the scalp even when the amount of the itching inhibitor is small.

  In order to solve the above-mentioned problems, the present inventors have studied a combination of a compound and a plant extract that are said to exhibit anti-inflammatory activity, and further added glycyrrhizic acid and / or glycyrrhizinate to suppress the occurrence of itch. As a result of diligent research on whether the shampoo generation rate can be further reduced by the combined use with other compounds, the above-mentioned problem can be solved by the combined use of 3-succinyloxyglycyrrhetinic acid and / or a salt thereof. The headline and the present invention have been completed.

  That is, the shampoo of the present invention comprises a surfactant, one or more itch inhibitors (A) selected from the group consisting of glycyrrhizic acid and glycyrrhizinate, 3-succinyloxyglycyrrhetinic acid and 3-succinyl. One or two or more stagnation inhibitors (B) selected from the group consisting of oxyglycyrrhetinate are blended.

In the present invention, the ratio of the mass _{W 2} with respect to the total weight _{W t} of the mass _{W 2} of the mass _{W 1} and the itching inhibitor of the itching inhibitor _{(A) (B) (W} 2 / W t) is 0.45 or less. This W ₂ / W _t is extremely low, but it is possible to achieve the same stagnation rate suppression as that exceeding 0.45. Preferably has a total weight W _t of the mass W ₂ of the mass W ₁ and the itching inhibitor of the itching inhibitor (A) (B) is not more than 1.00 wt%, keep lower the incidence of itching be able to.

  Furthermore, in the present invention, an amino acid anionic surfactant is preferably blended as the surfactant. Although the amino acid anionic surfactant is gentle to the skin, it is said that it tends to cause itching depending on the constitution of the user, but it suppresses the occurrence of itching by the combined use of the itching inhibitors (A) and (B). be able to.

  In the present invention, as the surfactant, one or two or more surfactants selected from the group consisting of amphoteric surfactants, nonionic surfactants and non-amino acid anionic surfactants are blended. In addition, the amount of the amino acid-based anionic surfactant is preferably 10.0% by mass or less, and in order to further suppress the stagnation, the amount of the amino acid-based anionic surfactant is 7.0% by mass. % Or less is more preferable.

  According to the present invention, it is possible to provide a shampoo that is excellent in suppressing the occurrence of itching in the scalp even when the amount of the itching inhibitor is small by blending the itching inhibitor (A) and the itching inhibitor (B). It becomes possible.

The present invention will be described below.
The shampoo of the present invention comprises a surfactant, one or more itch inhibitors (A) selected from the group consisting of glycyrrhizic acid and glycyrrhizinate, 3-succinyloxyglycyrrhetinic acid and 3-succinyloxyglycyrrhetin One or two or more stagnation inhibitors (B) selected from the group consisting of acid salts are blended. Such a shampoo is obtained by blending the stagnation inhibitors (A) and (B) with water together with a surfactant, and may further be blended with any known shampoo raw material.

(Surfactant)
The surfactant that can be blended in the shampoo of the present invention is not particularly limited, and one or more selected from anionic surfactants, amphoteric surfactants, nonionic surfactants and the like are used. be able to.

  The above-mentioned anionic surfactant is a surfactant excellent in cleaning and removing ability such as secretions adhering to the scalp and hair, dandruff, dirt adhering from the outside, and used hair styling agent. Examples of the anionic surfactant include amino acid anionic surfactant (for example, N-acyl glutamate), fatty acid salt, alkyl ether carboxylate, fatty acid amide ether carboxylate, fatty acid amide ether carboxylic acid, acyl lactic acid. Carboxylic acid anionic surfactants such as salts; alkane sulfonate, α-olefin sulfonate, α-sulfo fatty acid methyl ester salt, acyl isethionate, alkyl glycidyl ether sulfonate, alkyl sulfosuccinate, alkyl sulfoacetic acid Sulfonic acid anionic surfactants such as salts, alkylbenzene sulfonates, alkylnaphthalene sulfonates, N-acylmethyl taurates; alkyl sulfates, alkyl ether sulfates, alkyl aryl ether sulfates, fatty acid alkanos Sulfate anionic surfactants such as uramide sulfate and fatty acid monomonoglyceride sulfate; phosphates such as alkyl phosphate, polyoxyethylene alkyl ether phosphate, alkylaryl ether phosphate, fatty acid amide ether phosphate Anionic surfactants. The amount of the anionic surfactant in the shampoo of the present invention is not particularly limited, but is preferably 5.0 to 20.0% by mass, and more preferably 7.0 to 16.0% by mass.

  When making the shampoo of the present invention gentler to the skin, it is preferable to blend one or more amino acid type anionic surfactants. Examples of such amino acid anionic surfactants include N-coconut oil fatty acid acyl glutamate, N-lauroyl glutamate, N-myristoyl glutamate, N-palmitoyl glutamate, N-stearoyl glutamate, and N-oleoyl. N-acylglutamate surfactants such as glutamate; N-acylmethylalanine surfactants such as N-coconut oil fatty acid methylalanine salt, N-lauroylmethylalanine salt, and N-myristoylmethylalanine salt; N- N-acyl sarcosine acid surfactants such as coconut oil fatty acid sarcosine salt, N-lauroyl sarcosine salt, N-myristoyl sarcosine salt, and N-oleoyl sarcosine salt; N-coconut oil fatty acid acyl glutamate Has hair flexibility Preferred for enhanced. Here, examples of the salt form of the amino acid-based anionic surfactant include a sodium salt, a potassium salt, and a triethanolamine salt.

  When selecting an amino acid anionic surfactant as the surfactant, in order to further reduce the stagnation rate while maintaining sufficient practical detergency, amphoteric surfactants, nonionic surfactants, and non-ionic surfactants are used. In combination with one or more surfactants selected from amino acid anionic surfactants (anionic surfactants other than amino acid anionic surfactants), the amount of amino acid anionic surfactant in the shampoo is It is preferably 10.0% by mass or less, more preferably 7.0% by mass or less, and even more preferably 5.0% by mass or less.

  Examples of the amphoteric surfactant include imidazoline betaine, alkyl betaine, alkylamido betaine, and alkyl sulfobetaine. When the amphoteric surfactant is blended, the concentration of the amphoteric surfactant in the shampoo can be appropriately set.

  The nonionic surfactant has a lower cleaning ability than the anionic surfactant, but when used in combination with another surfactant, it increases the detergency of the other active agent and improves foaming properties. Examples of the nonionic surfactant include ethylene glycol monofatty acid ester, glycerin monofatty acid ester, polyglycerin fatty acid ester, sorbitan fatty acid ester, sucrose fatty acid ester, methyl glucoside fatty acid ester, alkyl polyglucoside, polyethylene glycol difatty acid. Ester, polyoxyethylene glycerin fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbitol fatty acid ester, polyoxyethylene methyl glucoside fatty acid ester, polyoxyethylene polyoxypropylene glycol, polyoxyethylene alkylamine, polyoxyethylene fatty acid amide And alkyldiethanolamide.

  Examples of the non-amino acid anionic surfactant include anionic surfactants other than the amino acid anionic surfactant among the examples of the anionic surfactant.

(Itching inhibitor)
The shampoo of the present invention is a blend of the stagnation inhibitor (A) and the stagnation inhibitor (B) listed below. Moreover, as long as it can suppress itch, you may mix | blend well-known anti-inflammatory agents other than a itch suppressant (A) and (B) as a itch suppressant.

  The itch suppressant (A) is one or more selected from the group consisting of glycyrrhizic acid and glycyrrhizinate. Examples of the salt include a sodium salt, a potassium salt, and an ammonium salt. In the present invention, two or more glycyrrhizinates having different salts may be blended.

  The stagnation inhibitor (B) is one or more selected from the group consisting of 3-succinyloxyglycyrrhetinic acid and 3-succinyloxyglycyrrhetinic acid salt. Examples of the salt include sodium salt, potassium salt, ammonium salt and the like. In the present invention, two or more kinds of 3-succinyloxyglycyrrhetinates having different salts may be blended.

Mass _{W 1} of itching inhibitor (A), when a mass of itching inhibitor (B) was the total mass of the _W 2, _{W 1} and _{W 2} and _{W t,} the amount of _{W 2} is less than _{W 1} W ₂ / W _t is preferably 0.45 or less, more preferably 0.40 or less, and even more preferably 0.35 or less, because it is excellent in suppressing stagnation. The lower limit of W ₂ / W _t is preferably 0.10, more preferably 0.15, and even more preferably 0.20.

  In the present invention, in order to suppress stagnation, the amount of the stagnation inhibitors (A) and (B) should be a certain amount or more, and in order to make shampoo inexpensive, the stagnation inhibitor (A) And it is good to reduce the compounding quantity of (B). Therefore, the stagnation inhibitor (A) in the shampoo is preferably 0.40% by mass or less, more preferably 0.05 to 0.30% by mass, and even more preferably 0.05 to 0.20% by mass. . On the other hand, the stagnation inhibitor (B) in the shampoo is preferably 0.10% by mass or less, more preferably 0.01 to 0.08% by mass, and even more preferably 0.02 to 0.06% by mass. .

  In order to make the shampoo inexpensive, the total amount of the stagnation inhibitors (A) and (B) in the shampoo is preferably 1.00% by mass or less, more preferably 0.30% by mass or less, and 0.20% by mass. The following are even more preferred:

(Optional raw material)
As described above, what is known as a shampoo raw material may be blended as an optional raw material for the shampoo of the present invention. For example, conditioning agents such as cationic surfactants to improve the feel, fingering, and gloss of hair, viscosity modifiers to adjust shampoo viscosity, anti-dandruff agents to prevent dandruff, water interfaces Hydrotrope to increase the solubility of the active agent, preservative to suppress the growth of bacteria in the shampoo, antioxidant to stabilize the quality of the shampoo, washing with metal ions contained in the water used during shampooing Examples thereof include a sequestering agent, a humectant, an ultraviolet absorber, a fragrance, and a colorant for suppressing performance degradation.

  In the present invention, the pH of the shampoo is preferably acidic. If the pH is low, the blended components may be precipitated. If the pH approaches neutral, the viscosity of the shampoo may be lowered. A pH of ~ 6.0 is preferred. When it is necessary to lower the pH, an acidic compound such as citric acid may be blended. When it is necessary to increase the pH, an alkaline compound such as sodium hydroxide may be blended.

  EXAMPLES Hereinafter, the present invention will be described more specifically with reference to examples, but the present invention is not limited to the examples.

Example 1
The shampoo of Example 1 was prepared by blending the following raw materials into water (21.57% by mass).
Dipotassium glycyrrhizinate: 0.10% by mass
3-succinyloxyglycyrrhetinic acid disodium salt: 0.03% by mass
N-coconut oil fatty acid acyl-sodium L-glutamate 24.2% by mass (Ajinomoto Healthy Supply, Amisoft CS-22): 48.0% by mass
2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine 36% by mass aqueous solution: 8.0% by mass
2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine 30% by mass aqueous solution: 2.0% by mass
Polyoxyethylene dioleic acid methyl glucoside: 3.5% by mass
Product containing 38% by mass of sucrose fatty acid ester (Daiichi Kogyo Seiyaku Co., Ltd., DK ester S-L18A):
2.0% by mass
O- [2-hydroxy-3- (trimethylammonio) propyl] hydroxyethylcellulose chloride: 0.8% by mass
Polyoxypropylene (1) Palm oil fatty acid monoisopropanolamide: 3.0% by mass
Glycerin: 9.5% by mass
Edetate disodium: 0.20% by mass
Fragrance: 0.3% by mass
Preservative: 1.0% by mass

(Example 2)
The shampoo of Example 2 was prepared by blending the following raw materials into water (33.15% by mass).
Dipotassium glycyrrhizinate: 0.10% by mass
3-succinyloxyglycyrrhetinic acid disodium salt: 0.05% by mass
N-coconut oil fatty acid acyl-sodium L-glutamate 25 mass% aqueous solution:
35.0% by mass
Polyoxyethylene sulfosuccinate disodium lauryl 31 mass% aqueous solution:
12.5% by mass
Lauric acid amidopropyl betaine 30 mass% aqueous solution: 10.0 mass%
Palm oil fatty acid N-methylethanolamide: 3.0% by mass
Polyethylene glycol distearate (1): 1.5% by mass
Product containing 38% by mass of sucrose fatty acid ester (Daiichi Kogyo Seiyaku Co., Ltd., DK ester S-L18A):
3.0% by mass
O- [2-hydroxy-3- (trimethylammonio) propyl] hydroxyethylcellulose chloride: 0.2% by mass
Edetate disodium: 0.2% by mass
Fragrance: 0.3% by mass
Preservative: 1.0% by mass

(Example 3)
N-coconut oil fatty acid acyl-L-sodium glutamate 25% by weight aqueous solution is 16% by weight, polyoxyethylene sulfosuccinate disodium lauryl 31% by weight aqueous solution is 25% by weight, and water is 39.65% by weight. The shampoo of Example 3 was prepared in the same manner as Example 2 except that the percentage was changed to%.

The following raw materials were blended in water (29.5% by mass) to prepare a shampoo of Comparative Example 1.
(Comparative Example 1)
Dipotassium glycyrrhizinate: 0.40% by mass
N-coconut oil fatty acid acyl-L-glutamic acid triethanolamine 30% by mass aqueous solution:
40.0% by mass
Product containing 30% by mass of cocoyl apple amino acid (manufactured by Seiwa Kasei Co., Ltd., PROTEOL APL): 3.3% by mass
Product containing 30% by mass of sodium laurylaminodipropionate (manufactured by Cognis, Delift 160C): 10.0% by mass
CAE (Ajinomoto Healthy Supply Co., Ltd.): 0.2% by mass
Anionic surfactant-containing product (Lion Corporation, Lipolane LJ-441): 5.4% by mass
Lauryl glycol hydroxypropyl ether: 1.5% by mass
1,2-oxybutylene laurate: 1.5% by mass
Nonionic surfactant-containing product (manufactured by Kao Corporation, Mydoll 10): 2.5% by mass
Nonionic surfactant-containing product (Nippon Rika Co., Ltd., NJE Bon ECS-600A):
2.5% by mass
Polyoxyethylene (10) methyl glucoside: 1.0% by mass
O- [2-hydroxy-3- (trimethylammonio) propyl] hydroxyethylcellulose chloride: 0.5% by mass
PROTECRAN sk-88 (manufactured by CRODA JAPAN): 0.3% by mass
Silicone emulsion (manufactured by Momentive Performance Materials Japan, XS65-B8124): 1.0% by mass
Fragrance: 0.3% by mass
Preservative: 0.1% by mass

(Comparative Example 2)
A comparison was made in the same manner as in Example 1 except that dipotassium glycyrrhizinate and disodium 3-succinyloxyglycyrrhetinate were replaced with 1.00% by mass of licorice extract (2% by mass of licorice extract manufactured by Kouki Co., Ltd.). The shampoo of Example 2 was prepared.

(Comparative Example 3)
Except that 0.50% by mass of Gentian extract (4.0% by mass of Gentian extract manufactured by Maruzen Pharmaceutical Co., Ltd. “Gentiana extract LA-M”) was added and the water was changed to 29.0% by mass. A shampoo of Comparative Example 3 was prepared in the same manner as Example 1.

(Test example)
Using the shampoos of Examples 1 to 3 and Comparative Examples 1 to 3, a sensory test regarding itching was performed. The detailed method of the sensory test was performed by the following method.

(Sensory test)
The sensory test was conducted with the number of panelists shown in Table 1 below. Each paneler used 80 mL of shampoo and 80 mL of treatment (“Clayde ER” manufactured by Milbon) once a day for 7 consecutive days. Thereafter, a questionnaire was given to each paneler regarding the presence or absence of scalp itchiness, and the percentage (percentage) of panelists who felt itchiness was determined. The results are also shown in Table 1 below. In the _{table, (W} 2 / _{W t)} represents the ratio of the mass _{W 2} with respect to the total weight _{W t} of the mass _{W 2} of the mass _{W 1} and the itching inhibitor of itching inhibitor (A) (B) .

  From the result of Table 1, although the total amount of the itch suppressants (A) and (B) of Examples 1 to 3 is less than the total amount of the itch suppressants (A) and anti-inflammatory agents of Comparative Examples 1 to 3, It turns out that the sensory test result of 1-3 is a better result than Comparative Examples 1-3.

Further, when the sensory test results of Examples 1 to 3 are confirmed by paying attention to W ₂ / W _t in Table 1, it can be seen that the occurrence of stagnation can be sufficiently suppressed even when W ₂ / W _t is 0.45 or less.

  Furthermore, if the sensory test result of Example 3 is confirmed, when the amino acid anionic surfactant is added to the shampoo, the occurrence of stagnation can be further suppressed by setting the amino acid anionic surfactant to 7% by mass or less. I understand.

Claims (6)

  From a group consisting of a surfactant, one or more itch inhibitors (A) selected from the group consisting of glycyrrhizic acid and glycyrrhizinate, and 3-succinyloxyglycyrrhetinic acid and 3-succinyloxyglycyrrhetinic acid salt A shampoo characterized by blending one or more selected stagnation inhibitors (B). The ratio of the mass _{W 2} with respect to the total weight _{W t} of the mass _{W 2} of the mass _{W 1} and the itching inhibitor of the itching inhibitor _{(A) (B) (W} 2 / W t) is 0.45 or less The shampoo according to claim 1. The total weight _{W t} of the mass _{W 2} of the mass _{W 1} and the itching inhibitor of the itching inhibitor (A) (B) is a shampoo according to claim 1 or 2 is 1.00 wt% or less.   The shampoo according to any one of claims 1 to 3, wherein an amino acid anionic surfactant is blended as the surfactant.   As the surfactant, one or more surfactants selected from the group consisting of amphoteric surfactants, nonionic surfactants and non-amino acid anionic surfactants are blended, and the amino acid type The shampoo according to claim 4, wherein the amount of the anionic surfactant is 10.0% by mass or less.   As the surfactant, one or more surfactants selected from the group consisting of amphoteric surfactants, nonionic surfactants and non-amino acid anionic surfactants are blended, and the amino acid type The shampoo according to claim 4, wherein the amount of the anionic surfactant is 7.0% by mass or less.