JP2005194290A - Cleansing cosmetic - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To prepare a cleansing cosmetic which is low in causing stimulation. <P>SOLUTION: This cleansing cosmetic contains an antiinflammatory component. The antiinflammatory component is especially a glycyrrhizin analog and/or a burdock extract. The glycyrrhizin analog is especially a stearyl glycyrrhetinate. Furthermore, a diglyceryl tetraolate is added to provide the cleansing cosmetic for sensitive skin. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

  The present invention relates to a cleansing cosmetic suitable for people with sensitive skin.

  In the cosmetics field, cleansing cosmetics are cosmetics that are difficult to remove with soaps such as make-up cosmetics and are used to remove oily stains. An emulsifier type is used, and this oily soil is removed by the solvent effect of the oily liquid component present in the internal phase. In such cleansing cosmetics, the biggest problem is that there are many oily components, so that the stimulation of such an oil agent itself as a solvent and the occurrence of irritation caused by rubbing during use. This kind of irritation is usually rarely observed, but in people with sensitive skin, such as those with atopic dermatitis, whose number has increased rapidly in recent years, the possibility of this occurrence is high, and this response is It was sought after.

  On the other hand, no attempt was made to include an anti-inflammatory component in cleansing cosmetics, and it was not known at all that cleansing cosmetics containing such anti-inflammatory components were suitable for people with sensitive skin. . In addition, it is known that diglycerin tetraoleate is suitable as a cleansing cosmetic ingredient because of its solvent properties. There was no known combination.

  The present invention has been made under such circumstances, and provides a cleansing cosmetic that has a low possibility of irritation even if it is a person with sensitive skin such as an atopic dermatitis patient. Let it be an issue.

  In view of such a situation, the present inventors have sought for cleansing cosmetics that have a low possibility of irritation even for people with sensitive skin, such as patients with atopic dermatitis. As a result, the inventors have found that such cleansing cosmetics can be obtained by adding a component having an anti-inflammatory action to the cleansing cosmetics, thereby completing the invention. That is, the present invention provides a cleansing cosmetic containing an anti-inflammatory component.

  ADVANTAGE OF THE INVENTION According to this invention, the cosmetics for cleansing with low possibility of irritation | stimulation expression can be provided.

(1) The component which has an anti-inflammatory action which is an essential component of the cleansing cosmetic composition of the present invention The cleansing cosmetic composition of the present invention is characterized by containing a component having an anti-inflammatory action. Examples of such an anti-inflammatory component include glycyrrhizic acid-related substances such as dipotassium glycyrrhizinate and stearyl glycyrrhetinate, and extracts of anti-inflammatory crude drugs such as burdock extract and birch extract. Of these, the particularly preferred cosmetics for cleansing of the present invention are stearyl glycyrrhetinate and burdock extract. These components are excellent in the action of suppressing the occurrence of stimulation by physical action in usage forms involving scrubbing such as cleansing. Thereby, the cosmetic for cleansing suppresses that a stimulus is expressed at the time of a makeup operation to a person with sensitive skin. In the cleansing cosmetic composition of the present invention, the total content of the components having anti-inflammatory action is 0.005 to 1% by weight, more preferably 0.05 to 0.5% by weight. This is because, if the amount is too small, the expression of the stimulus may not be suppressed, and if the amount is too large, the effect reaches a peak and the economic effect may be small.

(2) Cleansing cosmetic of the present invention The cleansing cosmetic of the present invention is characterized by containing the anti-inflammatory component as an essential component. The cosmetic for cleansing referred to in the present invention is a cosmetic for removing oily components, and its dosage form includes a water-in-oil emulsified cream, a water-in-oil emulsified emulsion, an oil-in-water emulsified cream, Any of oil emulsions, multiphase emulsions, non-aqueous emulsions and the like can be applied. The cleansing cosmetic composition of the present invention contains, in addition to the above-mentioned components having anti-inflammatory action, any components that are usually used in such cosmetic products within a range not impairing the effects of the present invention. can do. Such optional components include, for example, hydrocarbons such as squalane, petrolatum, microcrystalline wax, esters such as jojoba oil, carnauba wax, octyldodecyl oleate, diglycerin tetraoleate, olive oil, beef tallow, coconut oil Triglycerides such as, fatty acids such as stearic acid, oleic acid, lithinoleic acid, higher alcohols such as oleyl alcohol, stearyl alcohol, octyldodecanol, anionic surfactants such as sulfosuccinic acid ester and sodium polyoxyethylene alkyl sulfate, alkyl Amphoteric surfactants such as betaine salts, cationic surfactants such as dialkylammonium salts, sorbitan fatty acid esters, fatty acid monoglycerides, their polyoxyethylene adducts, polyoxyethylene amines Nonionic surfactants such as kill ethers, polyoxyethylene fatty acid esters, polyhydric alcohols such as polyethylene glycol, glycerin, 1,3-butanediol, thickening / gelling agents, antioxidants, UV absorbers, It can contain coloring agents, preservatives, powders, active ingredients such as vitamins, and the like. Among these optional components, it is particularly preferable to contain diglycerin tetraoleate as an ester oil. This is already known to be excellent in the action of dissolving and removing components that are difficult to remove even with ordinary cleansing cosmetics such as high melting point waxes. According to the study of the present inventor, as shown in the examples described later, this oil agent has a function of remarkably enhancing the effects of the present invention with little irritation to the skin during rubbing. The preferable content of diglycerin tetraoleate in the cleansing cosmetic composition of the present invention is 10 to 40% by weight, more preferably 20 to 30% by weight. This is because, if the amount is too small, the frictional stimulus reducing effect and cleansing action may not be recognized, and if the amount is too large, the effect may reach a peak and the degree of freedom of prescription may be impaired. Further, in the cleansing cosmetic composition of the present invention, it is also advantageous to contain N-lauroyl-L-glutamate di (cholesteryl octyldodecyl). This is because it also enhances the cleansing action without causing irritation to the skin. In the cleansing cosmetic composition of the present invention, a preferable content of the di-cholesteryl octyldodecyl N-lauroyl-L-glutamate is 0.1 to 10% by weight, and more preferably 0.5 to 5%. % By weight. This is because of the balance between cleansing effect and cost effectiveness. From the viewpoint of further reducing the elongation and reducing the friction coefficient, it is also preferable to contain 10 to 40% by weight, more preferably 15 to 25% by weight, of a branched fatty acid ester such as cetyl 2-ethylhexanoate. The cleansing cosmetic composition of the present invention can be produced by treating these components according to a conventional method. The cleansing cosmetic material thus obtained can remove oily stains without causing irritation even when used in a makeup operation including a rubbing operation, so even a person with sensitive skin can use it without any trouble. Therefore, the cleansing cosmetic of the present invention is also suitable as a cleansing for people with sensitive skin such as atopic dermatitis. Of course, the cleansing cosmetic of the present invention does not have any disadvantages even when used by a person with normal skin, and even when used by a person with normal skin, it belongs to the technical scope of the present invention.

  Hereinafter, the present invention will be described in more detail with reference to examples, but it goes without saying that the present invention is not limited to these examples.

<Example 1>
A cleansing cosmetic (oil-in-water emulsion) was prepared according to the formulation shown below. That is, the ingredients of A and B were each heated to 70 ° C., and the ingredient of B was gradually added to the ingredient of A, followed by stirring and cooling to obtain a cleansing cosmetic.
Ibehenyl alcohol 1 part by weight 2-ethylhexanoate cetyl 20 parts by weight N-lauroyl-L-glutamate di (cholesteryl octyldodecyl) 5 parts by weight liquid paraffin 25 parts by weight butylparaben 0.1 part by weight polyoxyethylene (45) stear Rate 2 parts by weight sorbitan monostearate 1 part by weight Self-emulsifying glyceryl monostearate 1 part by weight polyoxyethylene (120) isostearate 1 part by weight beeswax 2 parts by weight olive oil 25 parts by weight dimethicone 10c. s. 2 parts by weight Stearyl glycyrrhetinate 0.1 parts by weight 1,3-butanediol 3 parts by weight Burdock extract 0.1 parts by weight Water 11.7 parts by weight

<Example 2>
Using the cleansing cream of Example 1, a stimulus expression suppression test was performed. That is, the back of a white Hartley guinea pig (male, 300-400 g, 5 per group) was shaved, stripped 3 times with gummed tape, then wiped with 1% ethanol acetate solution, and then wiped with ethanol for sensitive skin. A model was created. A 0.1 g cleansing material was applied to a 4 cm × 4 cm portion of the back of this model, and after rubbing 5 times, wiped with absorbent cotton, and 30 minutes later, the skin condition was observed and judged. Judgment criteria are: ++: clear redness is recognized in many parts, +: clear redness is scattered in the form of dots, ±: indistinct but red impression,-: no redness is recognized Using. In Comparative Example 1, the essence of stearyl glycyrrhetinate and burdock of Example 1 was replaced with water. The results are shown in Table 1 as the number of appearance cases. Thus, it can be seen that the cleansing material of the present invention can be used with peace of mind even by people with sensitive skin.

<Example 3>
A cleansing cosmetic (oil-in-water emulsion) was prepared according to the formulation shown below. That is, the ingredients of A and B were each heated to 70 ° C., and the ingredient of B was gradually added to the ingredient of A, followed by stirring and cooling to obtain a cleansing cosmetic.
Ibehenyl alcohol 1 part by weight 2-ethylhexanoate cetyl 20 parts by weight N-lauroyl-L-glutamate di (cholesteryl octyldodecyl) 5 parts by weight liquid paraffin 25 parts by weight butylparaben 0.1 part by weight polyoxyethylene (45) stear Rate 2 parts by weight Sorbitan monostearate 1 part by weight Self-emulsifying glyceryl monostearate 1 part by weight polyoxyethylene (120) isostearate 1 part by weight beeswax 2 parts by weight diglycerin tetraoleate 25 parts by weight dimethicone 10c. s. 2 parts by weight Stearyl glycyrrhetinate 0.1 parts by weight 1,3-butanediol 3 parts by weight Burdock extract 0.1 parts by weight Water 11.7 parts by weight

<Example 4>
As in Example 2, the guinea pig sensitive skin model was examined together with Comparative Example 2 in which the cleansing stearyl glycyrrhetinate and burdock extract of Example 3 were replaced with water. As compared with Example 2, in the cleansing cosmetic of the present invention, the expression of stimuli was further suppressed by containing diglycerin tetraoleate.

<Example 5>
A cleansing cosmetic (oil-in-water emulsion) was prepared according to the formulation shown below. That is, the ingredients of A and B were each heated to 70 ° C., and the ingredient of B was gradually added to the ingredient of A, followed by stirring and cooling to obtain a cleansing cosmetic. This also had an excellent stimulus suppressing action.
Ibehenyl alcohol 1 part by weight 2-ethylhexanoate cetyl 20 parts by weight N-lauroyl-L-glutamate di (cholesteryl octyldodecyl) 5 parts by weight liquid paraffin 25 parts by weight butylparaben 0.1 part by weight polyoxyethylene (45) stear Rate 2 parts by weight Sorbitan monostearate 1 part by weight Self-emulsifying glyceryl monostearate 1 part by weight polyoxyethylene (120) isostearate 1 part by weight beeswax 2 parts by weight diglycerin tetraoleate 25 parts by weight dimethicone 10c. s. 2 parts by weight Stearyl glycyrrhetinate 0.1 parts by weight Dipotassium loglicyrrhizinate 0.1 part by weight 1,3-butanediol 3 parts by weight Burdock extract 0.1 part by weight Water 11.6 parts by weight

<Example 6>
About the cleansing creams of Examples 1, 3, and 5, a person with sensitive skin was used as a panelist (15 people per group, 45 people in total), and a use test was conducted for 8 weeks. The method of use was in accordance with the usage of normal cleansing cosmetics. After the use test was completed, a questionnaire was used to evaluate the feeling of use (smoothness and comfort in use) and cleansing power. Evaluation criteria used were ++: very good, +: good, ±: slightly good, −: slightly bad, −—: bad. The results are shown in Table 2. Thereby, it turns out that irritation | stimulation expression is suppressed and the cleansing cosmetics of this invention have the outstanding cleansing power so that even the person with sensitive skin can use it in comfort. Furthermore, since the difference in the degree of suppression of stimulation between Examples 1 and 3 in the use test is more open than in the animal experiment, it is smoother in use, in other words, no friction feeling. Can be said to greatly contribute to suppression of stimulation expression, in other words, comfort, and in this sense, the usefulness of diglycerin tetraoleate can be understood.

Claims (6)

A cleansing cosmetic that removes oily dirt by the solvent effect of an oily liquid component, and contains 1) an anti-inflammatory agent and 2) di-N-lauroyl-L-glutamate (cholesteryl octyldodecyl) A cleansing cosmetic. The cleansing cosmetic composition according to claim 1, wherein the anti-inflammatory agent is a glycyrrhizin analog and / or burdock extract. The cosmetic for cleansing according to claim 1 or 2, wherein the glycyrrhizin analogue is stearyl glycyrrhetinate. The cleansing makeup according to any one of claims 1 to 3, wherein a content of the N-lauroyl-L-glutamate di (cholesteryl octyldodecyl) is 0.1 to 10% by weight. Fee. The cleansing cosmetic composition according to any one of claims 1 to 4, further comprising 20 to 30% by weight of diglycerin tetraoleate. The cleansing cosmetic composition according to any one of claims 1 to 5, wherein the cosmetic composition is for sensitive skin.