JP2008179629A - Cosmetic sheet - Google Patents
Cosmetic sheet Download PDFInfo
- Publication number
- JP2008179629A JP2008179629A JP2007335525A JP2007335525A JP2008179629A JP 2008179629 A JP2008179629 A JP 2008179629A JP 2007335525 A JP2007335525 A JP 2007335525A JP 2007335525 A JP2007335525 A JP 2007335525A JP 2008179629 A JP2008179629 A JP 2008179629A
- Authority
- JP
- Japan
- Prior art keywords
- cosmetic
- ingredient
- extract
- sheet according
- cosmetic sheet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000008406 cosmetic ingredient Substances 0.000 claims abstract description 41
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Landscapes
- Cosmetics (AREA)
Abstract
Description
本発明は、顔面や手足などの化粧用のシートに関する。より詳細には、化粧料あるいは化粧料成分を保持させてなる化粧用シートに関する。該化粧用シートは顔面あるいは手足のパック、または化粧料あるいは化粧料成分を顔面または手足に浸透させるためなどに用いる。 The present invention relates to a cosmetic sheet such as a face and limbs. More specifically, the present invention relates to a cosmetic sheet in which cosmetics or cosmetic ingredients are held. The cosmetic sheet is used for facial or limb packs, or for allowing cosmetics or cosmetic ingredients to penetrate into the face or limbs.
近年、生活の質の向上とともに、皮膚のつや、潤い、白さの改善や、シワ防止などを目的とした化粧用シートが注目されている。
そのような化粧用シートとして、従来、木材繊維由来の紙に保湿剤などを貼付してなるシワ改善シートが提供されていたが（特許文献１参照）、基材が紙であるために破れ易く、また皮膚への密着性や装着感において劣るものであった。
装着時の皮膚に対する密着性及び装着感を向上させるために、カゼイン及びシルク由来の天然系原料をシート材料とする化粧用シートや、アミロースよりなる水不溶性ゲルシートに美容液を含浸させたシート状パック化粧料も提案されている（特許文献２および特許文献３参照）。
In recent years, cosmetic sheets aimed at improving the quality of life as well as improving skin gloss, moisture and whiteness, and preventing wrinkles have attracted attention.
As such a decorative sheet, a wrinkle improving sheet obtained by pasting a moisturizer or the like on paper derived from wood fiber has been provided (see Patent Document 1), but it is easily broken because the base material is paper. In addition, the adhesion to the skin and the feeling of wearing were inferior.
In order to improve the adhesion to the skin and the feeling of wearing at the time of wearing, a sheet-like pack in which a cosmetic liquid is impregnated with a cosmetic sheet using a natural raw material derived from casein and silk, or a water-insoluble gel sheet made of amylose. Cosmetics have also been proposed (see Patent Document 2 and Patent Document 3).
これらは、皮膚に対する密着性及び装着感において優れるが、ビタミンCなどの化粧料成分を含浸させて製品化しようとする際に、ビタミンCなどの化粧料成分がシートに液状で保持されることになるため、劣化され易いという欠点があった。また、シートの保水力に限界があるために、有効成分の保持量に限界があった。さらにまた、これらのシートでは有効成分を徐々に溶出させることができないために、有効成分が皮膚に吸収される前に劣化してしまうという問題点もあった。
本発明は、皮膚のパック用シートなどの化粧用シートにおいて、失活しにくく、かつ化粧料あるいは化粧料成分を有効に活用することができ、携行に便利な、密着性や装着感にも優れたシートを提供することを課題とする。 In cosmetic sheets such as skin pack sheets, the present invention is less likely to be deactivated, and can effectively use cosmetics or cosmetic ingredients, and is excellent in adhesion and wearing feeling, convenient for carrying. It is an object to provide a sheet.
本発明者らは、上記課題を解決するために鋭意検討した結果、繊維径がナノメートルオーダーの極微細繊維であるナノファイバーを用いて、ナノファイバーに化粧料あるいは化粧料成分を保持させることによって、上記課題が解決できることを見出した。
ナノファイバーからなる繊維状構造体（ナノウエブ）は、エレクトロスピニング法で得られるもので、包帯などの医療用途への適用が模索されているが、化粧品用途には適用されていない。
本発明は、保湿クリームなどの化粧料あるいはビタミンCなどの化粧料成分をナノファイバーに保持させることによって、製品流通や保管の際の失活を防止し、かつ、ナノファイバーの高い表面積によって、化粧料あるいは化粧料成分を有効に活用することができ、ナノファイバーの高い柔軟性により密着性及び装着感を改善できるものである。
そして、本発明の化粧用シートは、化粧料あるいは化粧料成分を保持して、使用時に水や化粧水もしくは油状の化粧料を添加して装着するものであるから、携行に便利で、かつ、使用時に化粧料および化粧料成分が徐々に溶出することによって、皮膚に徐々に吸収させることができる。
As a result of intensive studies to solve the above problems, the present inventors have used nanofibers that are ultrafine fibers with a fiber diameter of the order of nanometers, and by allowing the nanofibers to hold cosmetics or cosmetic ingredients. The present inventors have found that the above problems can be solved.
A fibrous structure (nanoweb) made of nanofibers is obtained by an electrospinning method and is being sought for medical use such as bandages, but is not applied to cosmetic use.
The present invention prevents cosmetics such as moisturizing creams or cosmetic ingredients such as vitamin C from being retained in the nanofibers, thereby preventing inactivation during product distribution and storage, and the high surface area of the nanofibers makes up the cosmetics. It is possible to effectively use a cosmetic or cosmetic ingredient, and to improve adhesion and wearing feeling due to the high flexibility of nanofibers.
And the cosmetic sheet of the present invention is a cosmetic sheet or cosmetic ingredient that holds, and is used by adding water, lotion or oily cosmetic during use, so it is convenient to carry, and When the cosmetic and cosmetic ingredients are gradually eluted at the time of use, the skin can be gradually absorbed.
すなわち、本発明は、次の発明に関する。
（１）高分子化合物のナノファイバーからなる網目状構造体に化粧料あるいは化粧料成分を保持させてなる化粧用シート。
（２）化粧料が保湿クリーム、スキンクリーム、美白クリーム、乳液、化粧水、美容液、美容ジェルである上記（１）に記載の化粧用シート。
（３）化粧料成分が、保湿剤、ホワイトニング成分、しみ取り成分、防皺成分、ビタミン類、抗炎症成分、血流促進成分、湿潤成分、及び油分の一種以上である上記（１）に記載の化粧用シート。
（４）化粧料成分がアスコルビン酸及びその誘導体である上記（１）記載の化粧用シート。
（５）化粧料成分が金属微粒子である上記（１）記載の化粧用シート。
（６）ナノファイバーからなる網目状構造体がエレクトロスピニング法によって形成されたものである上記（１）〜（５）のいずれかに記載された化粧用シート。
（７）ナノファイバーがポリ酢酸ビニル、アクリル酸系ポリマー、ポリビニルアルコール、プルラン、γ−ポリグルタミン酸、またはヒアルロン酸から形成されている上記（１）〜（６）のいずれかに記載された化粧用シート。
（８）水または溶剤に溶解させた高分子化合物溶液に化粧料または化粧料成分を添加して得た液体をエレクトロスピニングする工程を含む上記（１）〜（７）のいずれかに記載の化粧用シートの製造方法。
（９）水または溶剤に溶解させた高分子化合物溶液をエレクトロスピニングして得た網目状構造体に化粧料または化粧料成分を保持させる工程を含む上記（１）〜（７）のいずれかに記載の化粧用シートの製造方法。
That is, the present invention relates to the following invention.
(1) A cosmetic sheet obtained by holding cosmetics or cosmetic ingredients on a network structure composed of nanofibers of a polymer compound.
(2) The cosmetic sheet according to the above (1), wherein the cosmetic is a moisturizing cream, skin cream, whitening cream, milky lotion, lotion, cosmetic liquid, or cosmetic gel.
(3) The cosmetic component is a moisturizer, a whitening component, a stain removing component, an antifungal component, vitamins, an anti-inflammatory component, a blood flow promoting component, a moistening component, and an oil component as described in (1) above Cosmetic sheet.
(4) The cosmetic sheet according to (1), wherein the cosmetic ingredient is ascorbic acid and its derivatives.
(5) The cosmetic sheet according to (1), wherein the cosmetic ingredient is metal fine particles.
(6) The cosmetic sheet described in any one of (1) to (5) above, wherein the network structure composed of nanofibers is formed by an electrospinning method.
(7) The cosmetic according to any one of (1) to (6), wherein the nanofiber is formed from polyvinyl acetate, acrylic acid polymer, polyvinyl alcohol, pullulan, γ-polyglutamic acid, or hyaluronic acid. Sheet.
(8) The makeup according to any one of (1) to (7), including a step of electrospinning a liquid obtained by adding a cosmetic or a cosmetic ingredient to a polymer compound solution dissolved in water or a solvent. Sheet manufacturing method.
(9) Any of the above (1) to (7), which comprises a step of retaining cosmetics or cosmetic ingredients in a network structure obtained by electrospinning a polymer compound solution dissolved in water or a solvent The manufacturing method of the cosmetic sheet of description.
本発明によって、顔面や手足などの化粧用シートにおいて、保存性、密着性、装着感を向上することができ、かつ化粧料あるいは化粧料成分を有効に活用することができ、しかも携行にも便利なシートを得ることができた。 According to the present invention, in a cosmetic sheet such as a face and limbs, it is possible to improve storage stability, adhesion, and wearing feeling, and it is possible to effectively use cosmetics or cosmetic ingredients, and it is also convenient to carry. I was able to get a good sheet.
以下に、本発明を具体的に説明するが、本発明はそれに限定されるものではない。
近年、エレクトロスピニング法によって得られた高分子化合物のナノファイバーからなる繊維構造体（ナノウエブ）が注目されている。サブミクロンあるいはナノメートルオーダーの超微細繊維あるいは繊維構造物は、エレクトロスピニング法により種々の高分子化合物について容易に得られる。現在までに、ポリビニルアルコール、ポリカーボネート、ポリアミド、ポリウレタン、ポリメタクリレート、ポリエチレンオキサイド、ポリアニリン、コラーゲン、ポリスチレン、ポリビニルフェノール、ポリ塩化ビニル、ポリアクリル酸、酢酸セルロース、ポリカプロラクトン、ポリエチレン−ポリビニルアルコール共重合体、ポリエチレンテレフタレートなど１００種以上の高分子化合物についてエレクトロスピニング法でナノファイバーが得られている。
Hereinafter, the present invention will be specifically described, but the present invention is not limited thereto.
In recent years, fiber structures (nanowebs) comprising nanofibers of polymer compounds obtained by electrospinning have attracted attention. Submicron or nanometer order ultrafine fibers or fiber structures can be easily obtained for various polymer compounds by electrospinning. To date, polyvinyl alcohol, polycarbonate, polyamide, polyurethane, polymethacrylate, polyethylene oxide, polyaniline, collagen, polystyrene, polyvinylphenol, polyvinyl chloride, polyacrylic acid, cellulose acetate, polycaprolactone, polyethylene-polyvinyl alcohol copolymer, Nanofibers have been obtained by electrospinning for 100 or more kinds of polymer compounds such as polyethylene terephthalate.
典型的ナノファイバーは、繊維径に分布があり、多孔膜（ウエブ）としてランダムに配向している。エレクトロスピニング法で得られたナノファイバーは、１００μｍ以上の長さと３０〜２０００ｎｍの範囲の繊維径を有している。ナノウエブは、連続膜の１０倍〜１００倍の表面積を持っている。ナノフウエブの応用として、濾過、複合材、包帯、医薬品伝送担体、骨や軟骨組織再生のためのスカフォルド（足場）、ソーラーシステム、触媒、センサーなどが期待されている。 Typical nanofibers have a distribution in fiber diameter and are randomly oriented as a porous film (web). Nanofibers obtained by electrospinning have a length of 100 μm or more and a fiber diameter in the range of 30 to 2000 nm. A nanoweb has a surface area 10 to 100 times that of a continuous film. Nanofiber applications are expected to include filtration, composites, bandages, drug delivery carriers, scaffolds for bone and cartilage tissue regeneration, solar systems, catalysts, sensors, and the like.
現在まで、エレクトロスピニング法ナノウエブについて、最もよく研究されているのは医療用途であるが、本発明者らは、本発明によりエレクトロスピニング法ナノウエブの化粧用シートとしての新規な適用法を提供することができた。
化粧用シートは例えば図１のようなものである。
To date, the electrospinning nanoweb has been most frequently studied for medical use, but the present inventors provide a novel application method of electrospinning nanoweb as a cosmetic sheet according to the present invention. I was able to.
The decorative sheet is, for example, as shown in FIG.
本発明の化粧用シートに用いられる高分子化合物は、限定されるものではないが、ポリビニルアルコール、ポリスチレン、ポリカ−ボネート、ポリアクリル酸、ポリアクリル酸メチル、あるいはポリアクリル酸ブチル/イソプロピルアクリルアミド/ジメタクリル酸ポリエチレングリコール共重合体（一丸ファルコス（株）製メビオールジェル（商品名））などのアクリル酸系ポリマー、ポリ塩化ビニル、ポリエチレンテレフタレート、セルロース、ナイロン６６、ナイロン４６、ポリアミド、ポリウレタン、ポリビニルアルコール、ポリ乳酸、ポリカプロラクトン、ポリエチレングリコール、ポリ乳酸グリコール、ポリエチレン・ビニルアセテート、ポリエチレン・ビニルアルコール、ポリ酢酸ビニル、ポリエチレンオキシド、コラーゲン等のタンパク質、プルラン、ヒアルロン酸、ポリ-γ-グルタミン酸、変性コーンスターチ、β-グルカン、グルコオリゴ糖などの多糖類、ポリエチレン・ビニルアルコール / ポリ乳酸 ポリマーブレンド、ポリメタクリル酸メチル / アクリロニトリル ポリマーブレンド、ポリアニリン/ ポリエチレンオキシド ポリマーブレンド、コラーゲン / ポリエチレンオキシド ポリマーブレンド、シルク / ポリエチレンオキシド ポリマーブレンド、ポリアニリン / ポリスチレン ポリマーブレンドが上げられる。皮膚への適合性を考慮すると、特にポリ酢酸ビニル（PVAｃ）、ポリアクリル酸（ＰＡＡ）やポリビニルアルコール（ＰＶＡ）、ポリエチレンオキシド(PEO)、コラーゲンなどのタンパク質、プルラン、ヒアルロン酸、ポリ-γ-グルタミン酸、変性コーンスターチ、β-グルカン、グルコオリゴ糖などの種々の多糖類が好ましい。 The polymer compound used in the cosmetic sheet of the present invention is not limited, but polyvinyl alcohol, polystyrene, polycarbonate, polyacrylic acid, polymethyl acrylate, or polybutyl acrylate / isopropyl acrylamide / di-acid. Acrylic acid polymers such as polyethylene glycol methacrylate copolymer (Mebiol Gel (trade name) manufactured by Ichimaru Falcos Co., Ltd.), polyvinyl chloride, polyethylene terephthalate, cellulose, nylon 66, nylon 46, polyamide, polyurethane, polyvinyl alcohol , Polylactic acid, polycaprolactone, polyethylene glycol, polylactic glycol, polyethylene vinyl acetate, polyethylene vinyl alcohol, polyvinyl acetate, polyethylene oxide, collagen, etc. Proteins, pullulan, hyaluronic acid, poly-γ-glutamic acid, modified corn starch, β-glucan, gluco-oligosaccharide and other polysaccharides, polyethylene / vinyl alcohol / polylactic acid polymer blends, polymethyl methacrylate / acrylonitrile polymer blends, polyaniline / polyethylene oxide Polymer blends, collagen / polyethylene oxide polymer blends, silk / polyethylene oxide polymer blends, polyaniline / polystyrene polymer blends. Considering compatibility with skin, proteins such as polyvinyl acetate (PVAc), polyacrylic acid (PAA), polyvinyl alcohol (PVA), polyethylene oxide (PEO), collagen, pullulan, hyaluronic acid, poly-γ- Various polysaccharides such as glutamic acid, modified corn starch, β-glucan and gluco-oligosaccharide are preferred.
エレクトロスピニング法によるナノウエブは、次のような手法で製造される。
水または溶媒に高分子化合物が溶解されて、エレクトロスピニングされる。エレクトロスピニング工程の概念を図２に示す。研磨されたステンレス管がアルミホイルで覆われ約２０〜３００rpmで回転される。プラスチックシリンジが約１〜２０ｍ／分のスピードでステンレス管に対して平行に往復移動可能なスタンドにクランプされる。中でも、ステンレス管の回転速度が約６０rpmで、プラスチックシリンジの移動速度が約６ｍ／分であることが好ましい。管の回転速度とスタンドの移動速度はコンピューター制御される。高分子溶液はシリンジに入れられる。高電圧給電装置（FC30P4、Glassman High Voltage Inc,USA)の電極は高分子溶液中に浸漬された銅線に連結される。電圧は０〜３０ｋV、シリンジとコレクター（ステンレス管）の距離（TCD)は３〜１５ｃｍに設定された。均一なナノファイバーウエブ（図３）がアルミホイルの表面に積層される。
Nanowebs produced by electrospinning are manufactured by the following method.
The polymer compound is dissolved in water or a solvent and electrospun. The concept of the electrospinning process is shown in FIG. The polished stainless steel tube is covered with aluminum foil and rotated at about 20 to 300 rpm. A plastic syringe is clamped to a stand that can reciprocate in parallel with the stainless steel tube at a speed of about 1 to 20 m / min. In particular, it is preferable that the rotational speed of the stainless steel tube is about 60 rpm and the moving speed of the plastic syringe is about 6 m / min. The tube rotation speed and stand movement speed are computer controlled. The polymer solution is placed in a syringe. The electrode of the high voltage power supply device (FC30P4, Glassman High Voltage Inc, USA) is connected to a copper wire immersed in a polymer solution. The voltage was set to 0 to 30 kV, and the distance (TCD) between the syringe and the collector (stainless steel tube) was set to 3 to 15 cm. A uniform nanofiber web (FIG. 3) is laminated to the surface of the aluminum foil.
本発明の化粧用シートでは、ナノウエブに化粧料あるいは化粧料として有効な成分を保持させる。
本発明において保持させるとは、ナノウエブの表面上に保持させる場合、ナノウエブの内部に保持させる場合、ナノファイバー内に保持（内包）させる場合、およびこれらの保持形態を組み合せる場合のいずれをも含む。
化粧料あるいは化粧料成分を保持させる方法は、例えば、次の方法である。
１ 高分子化合物溶液に化粧料あるいは化粧料成分を混ぜて、エレクトロスピニングする。
２ 化粧料成分粉末をエレクトロスピニング中スプレーする。
３ ナノウエブが化粧料あるいは化粧料成分分散液に浸漬され、乾燥され、パッケージに封入される。
１のポリマー溶液に化粧料あるいは化粧料成分を混合して、分散液をエレクトロスピニングする方法が、化粧料成分の脱落が少ないので最適である。さらに、この方法によると、化粧料あるいは化粧料成分をナノウエブ中に内包できるので、空気との接触が抑えられ、失活や劣化をさらに抑えることができる。
いずれで製造した化粧用シートにおいても、化粧料あるいは化粧料成分はナノウエブに保持され、シートの使用時に水を加えることによって、化粧料あるいは化粧料成分が徐々に放出される。
In the cosmetic sheet of the present invention, the nanoweb is made to hold cosmetics or ingredients effective as cosmetics.
Holding in the present invention includes any of holding on the surface of the nanoweb, holding inside the nanoweb, holding (encapsulating) in the nanofiber, and combining these holding forms. .
The method of retaining cosmetics or cosmetic ingredients is, for example, the following method.
1 Cosmetics or cosmetic ingredients are mixed into the polymer compound solution and electrospun.
2 Spray cosmetic ingredient powder during electrospinning.
3 The nanoweb is dipped in a cosmetic or cosmetic ingredient dispersion, dried and enclosed in a package.
The method of mixing cosmetics or cosmetic ingredients in one polymer solution and electrospinning the dispersion is optimal because the cosmetic ingredients are less dropped. Furthermore, according to this method, since cosmetics or cosmetic ingredients can be encapsulated in the nanoweb, contact with air can be suppressed, and deactivation and deterioration can be further suppressed.
In any of the manufactured cosmetic sheets, the cosmetics or cosmetic ingredients are held on the nanoweb, and the cosmetics or cosmetic ingredients are gradually released by adding water when the sheets are used.
化粧料としては、保湿クリーム、スキンクリーム、美白クリーム、乳液、化粧水、美容液、美容ジェルなどのスキンケアに用いられる化粧料全般が用いられる。 化粧料成分としては、化粧品学的に許容される皮膚に有効な成分であればよく、特に限定されない。保湿剤、ホワイトニング成分、しみ取り成分、防皺成分、ビタミン類、抗炎症成分、血流促進成分、湿潤成分、油分、金属微粒子など化粧料に用いられる成分を単独あるいは組み合せて用いることができる。
例えば、アーモンド油、アクリル酸アルキルコポリマー、麻セルロース、アシタバエキス、アスコルビン酸、アスコルビン酸Ｎａ、キサンチン、アスタキサンチン、アスパラガスエキス、アスパラギン酸、アズレン、アセロラエキス、アデノシン三リン酸２Ｎａ、アボカド油、アマチャエキス、アミノ酪酸、アラニン、アラントイン、アルギニン、アルギン酸Ｎａ、アルジルリン、アルテアエキス、アルニカエキス、アルブミン、アロエベラエキス‐２−キダチアロエエキス、安息香酸塩Ｎａ、イチョウエキス、イノシトール、ウコンエキス、ウワウルシエキス、エイジツエキス、塩化ナトリウム、オイスターエキス、オウゴンエキス、オウバクエキス、オタネニンジンエキス、オドリコソウエキス、オランダカラシエキス、オリーブ油、オリザノール、海塩、加水分解ケラチン、コラーゲン、加水分解コラーゲン、加水分解コンキリオン、加水分解シルク、加水分解卵殻膜、加水分解卵白、褐藻エキス、カフェイン、カミツレエキス、カラミン、カリンエキス、カロチン、カロットエキス、カワラヨモギエキス、甘草エキス、カンフル、キイチゴエキス、キウイエキス、キシリトール、キトサン、キュウリエキス、クオタニウム‐７３、クチナシエキス、クマザサエキス、クララエキス、グリコール酸、グリシン、グリセリン、グリチルリチン酸２Ｋ、グリチルレチン酸ステアリル、グルコース、グルタチオン、グルタミン酸、グレープフルーツエキス、クレマティスエキス、クロレラエキス、ケ−プアロエエキス、ゲンチアナエキス、紅茶エキス、コエンザイムＱ１０、コーヒーエキス、コーンスターチ、ココイル加水分解コラーゲンＫ、ココイル加水分解コラーゲンＮａ、ココベタイン、ゴボウエキス、ゴマ油、コムギデンプン、コムギ胚芽エキス、コメヌカエキス、コレステロール、コンフリーエキス、酢酸トコフェロール、酢酸レチノール、サザンカオイル、サフラワー油、サリチル酸、サリチル酸Ｎａ、酸化亜鉛、酸化チタン、サンザシエキス、シアノコバラミン、シイタケエキス、ジオウエキス、ジグリセリン、シコンエキス、シソエキス、ジヒドロコレステロール、ジフェニルジメチルメコン、シモツケソウエキス、酒石酸、ショウキョウエキス、ショウブ根エキス、シルク、シルクエキス、水添レシチン、スクワラン、ステアリルアルコール、ステアリン酸グリセリル、ステアリン酸スクロース、セイヨウキヅタエキス、セイヨウハッカエキス、セージエキス、セタノール、セラミド３、セリン、セルロースガム、ソウハクヒエキス、ソルビトール、ダイズエキス、ダイズ発酵エキス、月見草油、ドクダミエキス、トコフェロール、トレハロース、ナイアシンアミド、ニコチン酸トコフェロール、乳酸、乳酸Ｎａ、尿素、バクガエキス、ハチミツ、パパイン、ハマメリスエキス、パルミチン酸レチノール、パンテノール、ヒアルロン酸Ｎａ、ビオチン、ヒキオコシエキス、ヒマシ油、ヒマワリ油、ピリドキシンＨＣｌ、ビワ葉エキス、ブクリョウエキス、ブッチャーブルームエキス、ブドウエキス、ブドウ種子油、プラセンタエキス、プルラン、ベタイン、ヘチマエキス、ボタンエキス、ホップエキス、ホホバオイル、メドウフォーム油、メトキシケイヒサンオクチル、メリッサエキス、メリロートエキス、メントール、モモ葉エキス、ヤグルマギクエキス、ヤシ油、ユーカリエキス、ユーカリ油、ユキノシタエキス、ユズエキス、ユリエキス、ヨウ化ニンニクエキス、葉酸、ヨクイニンエキス、ヨモギエキス、ラズベリーケトン、ラクトフェリン、ラノリン、ラベンダーエキス、リシン、リシンＨＣｌ、リノール酸、リボフラビン、硫酸Ｎａ、リンゴエキス、レイシエキス、レシチン、レゾルシン、レタスエキス、レモンエキス、レモン油、ロイシン、ローズ水、ローズヒップ油、ローズマリーエキス、ローマカミツレエキス、ローヤルゼリー、ワレモコウエキス、ＡＨＡ、ＢＧ、ＤＮＡ、ＰＣＡ‐Ｎａ、ＰＣＡ‐Ｎａアラントイン、ＰＧ、ＰＰＧ‐２８ブテス‐３５、ＲＮＡ‐ＮＡ、ｔ‐ブチルメトキシジベンゾイルメタン、α‐アルブチン、ムコ多糖、クレアチン、ジアセチルボルジン、ビタミンＡおよびその誘導体、ヒドロキノン、リポ核酸およびその塩、その他、アミノ酸およびその誘導体、各種植物エキス、各種動物由来抽出物、金属微粒子等などを用いることができる。金属微粒子としては、金、銀、白金、パラジウム等の化粧品用着色剤あるいは抗酸化剤等として用いられる金属を用いることができる。
As cosmetics, general cosmetics used for skin care such as moisturizing cream, skin cream, whitening cream, milky lotion, lotion, cosmetic liquid, and cosmetic gel are used. The cosmetic ingredient is not particularly limited as long as it is a cosmetically acceptable ingredient effective for the skin. Ingredients used in cosmetics such as humectants, whitening ingredients, stain-removing ingredients, antifungal ingredients, vitamins, anti-inflammatory ingredients, blood flow promoting ingredients, wetting ingredients, oils, and metal fine particles can be used alone or in combination.
For example, almond oil, alkyl acrylate copolymer, hemp cellulose, ashitaba extract, ascorbic acid, sodium ascorbate, xanthine, astaxanthin, asparagus extract, aspartic acid, azulene, acerola extract, adenosine triphosphate 2Na, avocado oil, achacha extract , Aminobutyric acid, alanine, allantoin, arginine, sodium alginate, alzylline, altea extract, arnica extract, albumin, aloe vera extract-2-kidachi aloe extract, benzoate Na, ginkgo biloba extract, inositol, turmeric extract, walnut extract, age extract, Sodium chloride, Oyster extract, Ogon extract, Oat extract, Panax ginseng extract, Odori extract, Dutch mustard extract, olive oil, o Zanol, sea salt, hydrolyzed keratin, collagen, hydrolyzed collagen, hydrolyzed conkylion, hydrolyzed silk, hydrolyzed eggshell membrane, hydrolyzed egg white, brown algae extract, caffeine, chamomile extract, calamine, karin extract, carotene, carrot extract , Kawara mugwort extract, licorice extract, camphor, raspberry extract, kiwi extract, xylitol, chitosan, cucumber extract, quaternium-73, gardenia extract, kumazasa extract, clara extract, glycolic acid, glycine, glycerin, glycyrrhizic acid 2K, stearyl glycyrrhetinate Glucose, glutathione, glutamic acid, grapefruit extract, clematis extract, chlorella extract, cape aloe extract, gentian extract, tea extract, coenzyme Q10, coffee Extract, corn starch, cocoyl hydrolyzed collagen K, cocoyl hydrolyzed collagen Na, cocobetaine, burdock extract, sesame oil, wheat starch, wheat germ extract, rice bran extract, cholesterol, comfrey extract, tocopherol acetate, retinol acetate, sasanca oil, safflower Oil, salicylic acid, sodium salicylic acid, zinc oxide, titanium oxide, hawthorn extract, cyanocobalamin, shiitake extract, diau extract, diglycerin, sycamore extract, perilla extract, dihydrocholesterol, diphenyldimethylmecon, citrus extract, tartaric acid, ginger extract, ginger root extract, Silk, silk extract, hydrogenated lecithin, squalane, stearyl alcohol, glyceryl stearate, sucrose stearate, Seyo Ukita extract, Atlantic mint extract, Sage extract, Cetanol, Ceramide 3, Serine, Cellulose gum, Sakuha extract, Sorbitol, Soybean extract, Soybean fermented extract, Evening primrose oil, Dokudami extract, Tocopherol, Trehalose, Niacinamide, Tocopherol nicotinate, Lactic acid, Lactic acid Na, Urea, Bakuga extract, Honey, Papain, Hamelis extract, Retinol palmitate, Panthenol, Hyaluronic acid Na, Biotin, Bamboo extract, Castor oil, Sunflower oil, Pyridoxine HCl, Loquat leaf extract, Bud extract, Butcher bloom extract, Grape Extract, grape seed oil, placenta extract, pullulan, betaine, loofah extract, button extract, hop extract, jojoba oil, meadow foam oil, metho Shikeihisan octyl, Melissa extract, Melilot extract, menthol, peach leaf extract, cornflower extract, coconut oil, eucalyptus extract, eucalyptus oil, yukinoshita extract, yuzu extract, lily extract, iodized garlic extract, folic acid, yokoinin extract, mugwort extract, raspberry ketone , Lactoferrin, lanolin, lavender extract, lysine, ricin HCl, linoleic acid, riboflavin, sodium sulfate, apple extract, litchi extract, lecithin, resorcin, lettuce extract, lemon extract, lemon oil, leucine, rose water, rosehip oil, rose Marie extract, Roman chamomile extract, Royal jelly, Walnut extract, AHA, BG, DNA, PCA-Na, PCA-Na allantoin, PG, PPG-28 Butes-35, RNA-N , T-butylmethoxydibenzoylmethane, α-arbutin, mucopolysaccharide, creatine, diacetylbordin, vitamin A and its derivatives, hydroquinone, liponucleic acid and its salts, other amino acids and their derivatives, various plant extracts, various animal origins An extract, metal fine particles, etc. can be used. As the metal fine particles, metals used as cosmetic colorants or antioxidants such as gold, silver, platinum and palladium can be used.
本発明の化粧用シートは、ナノウエブに化粧料成分が固体状で保持することもできるので、液体状態では不安定なビタミンＣなどでも失活しにくく、空気中でも安定であるという利点がある。乾燥状態で空気中、長期間、流通及び保管、携行ができるのは有利である。
また、ナノウエブは表面積が高いので、より多くの化粧料あるいは化粧料成分を保持することができ、よって、化粧料あるいは化粧料成分の浸透率が高くなるという効果も有する。
さらに、ナノウエブに保持された化粧料あるいは化粧料成分は、ナノウエブの繊維径が細く表面積が高いために、使用時に加水されたとき、拡散速度、液状化速度が早く、よって、皮膚への浸透速度が速いという効果も有する。
さらにまた、ナノウエブに保持された化粧料あるいは化粧料成分は、使用時に水や化粧水もしくは油状の化粧料を添加して装着してから、徐々に放出されることになるので、皮膚に徐々に吸収させることができ、放出後皮膚吸収前に化粧料あるいは化粧料成分が劣化することも避けることができる。
The cosmetic sheet of the present invention has the advantage that the cosmetic ingredient can be held in a solid state on the nanoweb, so that even vitamin C which is unstable in a liquid state is hardly deactivated and is stable in air. It is advantageous to be able to distribute, store and carry in the air in the dry state for a long time.
Further, since the nanoweb has a high surface area, it can hold more cosmetics or cosmetic ingredients, and thus has an effect of increasing the penetration rate of the cosmetics or cosmetic ingredients.
Furthermore, the cosmetics or cosmetic ingredients held on the nanoweb have a high diffusion rate and liquefaction rate when they are hydrated at the time of use due to the thin fiber diameter of the nanoweb and the high surface area. Has the effect of fast.
Furthermore, the cosmetics or cosmetic ingredients held on the nanoweb are released gradually after adding water, lotion or oily cosmetics when used, so that they are gradually released on the skin. It can be absorbed, and it is also possible to avoid deterioration of cosmetics or cosmetic ingredients after release and before skin absorption.
さらにまた、本発明の化粧用シートは、次のような効果も有する。
１ エレクトロスピニングされたナノウエブは、ナノ構造あるいはサブミクロン構造のために、シート中に水分湿分をより強く保持することができるので、有効時間を増加させることができる。
２ フィルムや不織布と違って、ナノウエブは非常にソフトな絹のような感触であり、皮膚に密着し、皮膚を傷めない。しかも、皮膚と高い接触面積を得ることができるので効率的な成分の放出ができる。
３ 生分解性または生体適合性ポリマーの使用によって皮膚アレルギーを起こさない。また、環境に悪影響がない。
４ 高価な化粧料あるいは化粧料成分でも、ロスなく有効に高分散保持することができるので、コストを安くすることができる。
５ 微細な繊維径のために、化粧用シートからの成分の落下を防止できる。
Furthermore, the cosmetic sheet of the present invention has the following effects.
1 Electrospun nanowebs can increase the effective time because they can hold moisture and moisture more strongly in the sheet due to nanostructures or submicron structures.
2 Unlike films and non-woven fabrics, nanowebs have a very soft silky feel that adheres to the skin and does not damage the skin. In addition, since a high contact area with the skin can be obtained, the components can be efficiently released.
3 Does not cause skin allergies due to the use of biodegradable or biocompatible polymers. Moreover, there is no adverse effect on the environment.
4. Even expensive cosmetics or cosmetic ingredients can be effectively highly dispersed and held without loss, so the cost can be reduced.
5 Because of the fine fiber diameter, it is possible to prevent components from falling from the cosmetic sheet.
本発明の化粧用シートは、使用時に水等を適量加えて装着する。皮膚にあてがう前に適量の水等をスプレー、浸漬などにより添加して、湿らせた上で装着しても良いし、皮膚にあてがった後、スプレーするなどの方法によって水等を添加しても良い。
[実施例]
The cosmetic sheet of the present invention is attached by adding an appropriate amount of water or the like at the time of use. Before applying to the skin, add an appropriate amount of water, etc. by spraying, dipping, etc. and moisten it or attach it to the skin, and then add water etc. by spraying etc. good.
[Example]
以下には、実施例及び試験例によって、本発明を具体的に説明するが、本発明はこれに限定されるものではない。 Hereinafter, the present invention will be specifically described by way of examples and test examples, but the present invention is not limited thereto.
＜化粧用シートの製造例１＞
アセトン(純正化学（株）製 11265-0382 純度>99.5％)にポリ酢酸ビニル(PVAc) (ALDRICH製 387932-500G 分子量500,000)を10wt％溶解する。この溶液にL(＋）−アスコルビン酸(和光純薬工業（株）製 016-04805 純度>99.5％)を、重量比がPVAc溶液：アスコルビン酸 = ９：１となるように分散させ、０．５時間攪拌する。図２に示されるエレクトロスピニング装置において、次の条件でエレクトロスピニングを行った。
エレクトロスピニング条件：印加電圧１５ｋV、TCD１５ｃｍ、注入速度１mＬ／ｈｒ、温度２５℃、湿度５０％RH。
<Production Example 1 of Cosmetic Sheet>
Dissolve 10 wt% of polyvinyl acetate (PVAc) (38793-500G molecular weight 500,000 from ALDRICH) in acetone (Pure Chemical Co., Ltd. 11265-0382 purity> 99.5%). In this solution, L (+)-ascorbic acid (016-04805 purity> 99.5%, manufactured by Wako Pure Chemical Industries, Ltd.) was dispersed so that the weight ratio was PVAc solution: ascorbic acid = 9: 1. Stir for 5 hours. In the electrospinning apparatus shown in FIG. 2, electrospinning was performed under the following conditions.
Electrospinning conditions: applied voltage 15 kV, TCD 15 cm, injection speed 1 mL / hr, temperature 25 ° C., humidity 50% RH.
＜溶出試験例＞
実施例１の方法で製造したビタミンC含有化粧用シートを水中に浸漬してビタミンC溶出量の経時変化を調べた。
本発明品では、浸漬直後は少量しか溶け出しておらず、時間が経つにつれ溶出量が増加し１０分経過時点で飽和した。このことは、本発明品から徐々に有効成分が溶出することを示している。
市販の化粧用シートでは上記のような挙動が見られない。
<Example of dissolution test>
The vitamin C-containing cosmetic sheet produced by the method of Example 1 was immersed in water, and the change with time in the elution amount of vitamin C was examined.
In the product of the present invention, only a small amount was dissolved immediately after the immersion, and the elution amount increased with time and became saturated after 10 minutes. This indicates that the active ingredient gradually elutes from the product of the present invention.
A commercially available cosmetic sheet does not exhibit the above behavior.
＜化粧用シートの製造例２＞
プルラン(（株）林原生物化学研究所製）およびβ-アルブチンおよび水を、重量比がプルラン：β-アルブチン：水 = 1：1：8となるように混合し、全成分が溶解するまで攪拌する。図２に示されるエレクトロスピニング装置において、次の条件でエレクトロスピニングを行った。
エレクトロスピニング条件：印加電圧 15ｋＶ、TCD１５ｃｍ、注入速度１mＬ／ｈｒ、温度２５℃、湿度５０％RH。
<Manufacture example 2 of a cosmetic sheet>
Pullulan (produced by Hayashibara Biochemical Laboratories Co., Ltd.), β-arbutin and water are mixed so that the weight ratio is pullulan: β-arbutin: water = 1: 1: 8, and stirred until all components are dissolved. To do. In the electrospinning apparatus shown in FIG. 2, electrospinning was performed under the following conditions.
Electrospinning conditions: applied voltage 15 kV, TCD 15 cm, injection speed 1 mL / hr, temperature 25 ° C., humidity 50% RH.
＜化粧用シートの製造例３＞
プルラン(（株）林原生物化学研究所製）およびコスメソームＴＭＱ１０（キューピー（株）製。登録商標。ユビキノンの水分散製剤）および水を、重量比がプルラン：コスメソームＴＭ１０：水 = 1：3：6となるように混合し、全成分が溶解するまで攪拌する。図２に示されるエレクトロスピニング装置において、次の条件でエレクトロスピニングを行った。
エレクトロスピニング条件：印加電圧 15ｋＶ、TCD１５ｃｍ、注入速度１mＬ／ｈｒ、温度２５℃、湿度５０％RH。
<Production Example 3 of Cosmetic Sheet>
Pullulan (manufactured by Hayashibara Biochemical Laboratories Co., Ltd.) and Cosmesome TM Q10 (manufactured by Kewpie Co., Ltd., registered trademark, water-dispersed preparation of ubiquinone) and water are in a weight ratio of pullulan: Cosmesome TM 10: water = 1 : Mix until 3: 6 and stir until all components are dissolved. In the electrospinning apparatus shown in FIG. 2, electrospinning was performed under the following conditions.
Electrospinning conditions: applied voltage 15 kV, TCD 15 cm, injection speed 1 mL / hr, temperature 25 ° C., humidity 50% RH.
＜化粧用シートの製造例４＞
PVA（和光純薬工業（株）製 160-03055 重合度約1500）を濃度が10wt％となるように水で溶解する。この溶液に（株）シーエスラボ社製スキンクリームを重量比がＰＶＡ溶液：スキンクリーム＝７：３となるように混合し、均一になるまで（2時間程度）攪拌する。図２に示されるエレクトロスピニング装置において、次の条件でエレクトロスピニングを行った。
エレクトロスピニング条件：印加電圧 15ｋＶ、TCD１５ｃｍ、注入速度１mＬ／ｈｒ、温度２５℃、湿度５０％RH。
<Production Example 4 for Cosmetic Sheet>
Dissolve PVA (manufactured by Wako Pure Chemical Industries, Ltd. 160-03055 degree of polymerization about 1500) with water to a concentration of 10 wt%. To this solution, a skin cream manufactured by Sea Slab Co., Ltd. is mixed so that the weight ratio is PVA solution: skin cream = 7: 3, and stirred until it becomes uniform (about 2 hours). In the electrospinning apparatus shown in FIG. 2, electrospinning was performed under the following conditions.
Electrospinning conditions: applied voltage 15 kV, TCD 15 cm, injection speed 1 mL / hr, temperature 25 ° C., humidity 50% RH.
＜化粧用シートの製造例５＞
PVA（和光純薬工業製 160-03055 重合度約1500）およびTEGO CosmoＴＭ C250（degussa製 。登録商標。表示名称：クレアチン）および水を、重量比がＰＶＡ：TEGO CosmoＴＭ C250：水 = 1：1：8となるように混合し、全成分が溶解するまで攪拌する。図２に示されるエレクトロスピニング装置において、次の条件でエレクトロスピニングを行った。
エレクトロスピニング条件：印加電圧 15ｋＶ、TCD１５ｃｍ、注入速度１mＬ／ｈｒ、温度２５℃、湿度５０％RH。
<Manufacture example 5 of a cosmetic sheet>
PVA (manufactured by Wako Pure Chemical Industries, Ltd. 160-03055, degree of polymerization about 1500), TEGO Cosmo ™ C250 (manufactured by degussa, registered trademark, display name: creatine), and water in a weight ratio of PVA: TEGO Cosmo ™ C250: water = 1: Mix until 1: 8 and stir until all components are dissolved. In the electrospinning apparatus shown in FIG. 2, electrospinning was performed under the following conditions.
Electrospinning conditions: applied voltage 15 kV, TCD 15 cm, injection speed 1 mL / hr, temperature 25 ° C., humidity 50% RH.
＜保湿試験例＞
実施例５で製造された化粧用シートについて、皮膚水分量を測ることによって保湿性を試験した。
（評価方法）
腕に５ｃｍ角に切り取ったナノファイバーシートを載せて水をスプレー噴霧しシート全面を濡らす。このとき噴霧した水の量は１ｍｌである。この評価試験においては、ナノファイバーシートは基材（ラップ）表面上に作成した。基材（ラップ）で覆うのは、密封効果による化粧料の皮膚への浸透を促進させるためである。この状態で放置し、１０分経過後基材（ラップ）上で作製したナノファイバーシートをはがす。これからさらに２５分経過後、評価装置を用いて評価を行なった。評価装置には、Courage+Khazaka（CK）社製 コルネオメーター（corneometer）ＣＭ ８２５を用いた。
シートを貼る前の状態と比較して、皮膚水分増加量を測定した。対照として、ＰＶＡ溶液を塗って基材（ラップ）上に作製したナノファイバーシートを用いた場合、及びスキンクリームを塗布して基材（ラップ）で覆った場合を評価した。このときのスキンクリームの塗布量は、ナノファイバーシートに含まれるスキンクリーム量に合わせた。
（評価結果）
被験者４人の結果を表１及び図５に示した。
<Moisturizing test example>
The cosmetic sheet produced in Example 5 was tested for moisture retention by measuring skin moisture.
(Evaluation methods)
A nanofiber sheet cut into 5 cm square is placed on the arm and sprayed with water to wet the entire surface of the sheet. The amount of water sprayed at this time is 1 ml. In this evaluation test, the nanofiber sheet was prepared on the surface of the substrate (wrap). The reason for covering with the base material (wrap) is to promote the penetration of the cosmetic into the skin by the sealing effect. Leave in this state and peel off the nanofiber sheet produced on the substrate (wrap) after 10 minutes. After an additional 25 minutes, evaluation was performed using an evaluation device. As an evaluation apparatus, a Corneometer CM 825 manufactured by Courage + Khazaka (CK) was used.
The amount of increase in skin moisture was measured in comparison with the state before the sheet was applied. As a control, a case where a nanofiber sheet prepared by applying a PVA solution on a substrate (wrap) was used, and a case where a skin cream was applied and covered with the substrate (wrap) were evaluated. The amount of skin cream applied at this time was adjusted to the amount of skin cream contained in the nanofiber sheet.
(Evaluation results)
The results of 4 subjects are shown in Table 1 and FIG.
Claims (9)
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| JP2007335525A JP2008179629A (en) | 2006-12-27 | 2007-12-27 | Cosmetic sheet |
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