JP2004067510A - 新規イミダゾール誘導体 - Google Patents
新規イミダゾール誘導体 Download PDFInfo
- Publication number
- JP2004067510A JP2004067510A JP35967197A JP35967197A JP2004067510A JP 2004067510 A JP2004067510 A JP 2004067510A JP 35967197 A JP35967197 A JP 35967197A JP 35967197 A JP35967197 A JP 35967197A JP 2004067510 A JP2004067510 A JP 2004067510A
- Authority
- JP
- Japan
- Prior art keywords
- group
- imidazole
- optionally substituted
- synthesis example
- material synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C*c1c(C2CCCCC2)[n]c(-c2ccccc2)n1 Chemical compound C*c1c(C2CCCCC2)[n]c(-c2ccccc2)n1 0.000 description 3
- OFDYXNADFLNNIS-UHFFFAOYSA-N Cc(cc1)ccc1-c1c(C(Nc2ncc[s]2)=O)nc(-c(cc2)ccc2[N+]([O-])=O)[nH]1 Chemical compound Cc(cc1)ccc1-c1c(C(Nc2ncc[s]2)=O)nc(-c(cc2)ccc2[N+]([O-])=O)[nH]1 OFDYXNADFLNNIS-UHFFFAOYSA-N 0.000 description 1
- LOTNAYHQASCNFZ-UHFFFAOYSA-N Cc(cc1)ccc1-c1c(C(Nc2ncc[s]2)=O)nc(-c2cccc3ccccc23)[n]1Cc1ccccc1 Chemical compound Cc(cc1)ccc1-c1c(C(Nc2ncc[s]2)=O)nc(-c2cccc3ccccc23)[n]1Cc1ccccc1 LOTNAYHQASCNFZ-UHFFFAOYSA-N 0.000 description 1
- MUXXRADAXSDKII-UHFFFAOYSA-N Cc(cc1)ccc1-c1c(C(Nc2ncc[s]2)=O)nc(-c2ccncc2)[nH]1 Chemical compound Cc(cc1)ccc1-c1c(C(Nc2ncc[s]2)=O)nc(-c2ccncc2)[nH]1 MUXXRADAXSDKII-UHFFFAOYSA-N 0.000 description 1
- IPEIODKDIGFSIW-UHFFFAOYSA-N Cc(cc1)ccc1C1=C(C(Nc2ncc[s]2)=O)N(CCN2CCOCC2)C(c2c(cccc3)c3ccc2)=CC1 Chemical compound Cc(cc1)ccc1C1=C(C(Nc2ncc[s]2)=O)N(CCN2CCOCC2)C(c2c(cccc3)c3ccc2)=CC1 IPEIODKDIGFSIW-UHFFFAOYSA-N 0.000 description 1
- QGJMNTWIRQWFJK-UHFFFAOYSA-N Nc(cc1)ccc1-c1nc(C(Nc2ncc[s]2)=O)c(-c(cc2)ccc2Cl)[nH]1 Chemical compound Nc(cc1)ccc1-c1nc(C(Nc2ncc[s]2)=O)c(-c(cc2)ccc2Cl)[nH]1 QGJMNTWIRQWFJK-UHFFFAOYSA-N 0.000 description 1
- NLQHCDOVARJSLP-UHFFFAOYSA-N O=C(c1c(-c2ccccc2)[nH]c(-c2cccc3ccccc23)n1)Nc1ncc[s]1 Chemical compound O=C(c1c(-c2ccccc2)[nH]c(-c2cccc3ccccc23)n1)Nc1ncc[s]1 NLQHCDOVARJSLP-UHFFFAOYSA-N 0.000 description 1
- VBWRAMWWICXOAD-UHFFFAOYSA-N [O-][N+](c(cc1)ccc1-c1c(C(Nc2ncc[s]2)=O)nc(-c2cccc3ccccc23)[nH]1)=O Chemical compound [O-][N+](c(cc1)ccc1-c1c(C(Nc2ncc[s]2)=O)nc(-c2cccc3ccccc23)[nH]1)=O VBWRAMWWICXOAD-UHFFFAOYSA-N 0.000 description 1
- ZBGVHAYPMHZREG-UHFFFAOYSA-N [O-][N+](c(cc1)ccc1-c1nc(C(O)=O)c(-c2ccccc2)[nH]1)=O Chemical compound [O-][N+](c(cc1)ccc1-c1nc(C(O)=O)c(-c2ccccc2)[nH]1)=O ZBGVHAYPMHZREG-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP35967197A JP2004067510A (ja) | 1997-12-26 | 1997-12-26 | 新規イミダゾール誘導体 |
| AU16901/99A AU1690199A (en) | 1997-12-26 | 1998-12-24 | Novel imidazole derivatives |
| PCT/JP1998/005930 WO1999033827A1 (fr) | 1997-12-26 | 1998-12-24 | Nouveaux derives d'imidazole |
| US09/598,216 US6288061B1 (en) | 1997-12-26 | 2000-06-21 | Imidazole derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP35967197A JP2004067510A (ja) | 1997-12-26 | 1997-12-26 | 新規イミダゾール誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2004067510A true JP2004067510A (ja) | 2004-03-04 |
Family
ID=18465701
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP35967197A Pending JP2004067510A (ja) | 1997-12-26 | 1997-12-26 | 新規イミダゾール誘導体 |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP2004067510A (fr) |
| AU (1) | AU1690199A (fr) |
| WO (1) | WO1999033827A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009529555A (ja) * | 2006-03-15 | 2009-08-20 | ４エスツェー アクチェンゲゼルシャフト | 新規複素環式ＮＦ−κＢ阻害薬 |
| JP2012504617A (ja) * | 2008-10-03 | 2012-02-23 | プロテオテック・インコーポレイテッド | β−アミロイド疾患およびシヌクレイノパチーを処置するための化合物、組成物、および方法 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000078758A1 (fr) * | 1999-06-21 | 2000-12-28 | Mitsubishi Pharma Corporation | Nouveaux derives d'imidazole |
| US9029408B2 (en) | 2008-06-16 | 2015-05-12 | Gtx, Inc. | Compounds for treatment of cancer |
| ES2927660T3 (es) | 2008-06-16 | 2022-11-10 | Univ Tennessee Res Found | Compuestos para el tratamiento del cáncer |
| US9447049B2 (en) | 2010-03-01 | 2016-09-20 | University Of Tennessee Research Foundation | Compounds for treatment of cancer |
| JP5879273B2 (ja) | 2010-03-01 | 2016-03-08 | ジーティーエックス・インコーポレイテッド | 癌を処置するための化合物 |
| BR112013000925A2 (pt) | 2010-07-15 | 2020-12-01 | Bayer Intellectual Property Gmbh | compostos heterocíclicos como pesticidas |
| US8618125B2 (en) | 2011-01-14 | 2013-12-31 | Heptiva LLC | Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health maintenance |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0753716B2 (ja) * | 1986-07-02 | 1995-06-07 | 吉富製薬株式会社 | イミダゾ−ルカルボキサミド誘導体 |
-
1997
- 1997-12-26 JP JP35967197A patent/JP2004067510A/ja active Pending
-
1998
- 1998-12-24 WO PCT/JP1998/005930 patent/WO1999033827A1/fr not_active Ceased
- 1998-12-24 AU AU16901/99A patent/AU1690199A/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009529555A (ja) * | 2006-03-15 | 2009-08-20 | ４エスツェー アクチェンゲゼルシャフト | 新規複素環式ＮＦ−κＢ阻害薬 |
| JP2012504617A (ja) * | 2008-10-03 | 2012-02-23 | プロテオテック・インコーポレイテッド | β−アミロイド疾患およびシヌクレイノパチーを処置するための化合物、組成物、および方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999033827A1 (fr) | 1999-07-08 |
| AU1690199A (en) | 1999-07-19 |
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