JP2002520049A - 改良された洗浄性能を有するポリペプチド−ポリマー接合体 - Google Patents

改良された洗浄性能を有するポリペプチド−ポリマー接合体

Info

Publication number: JP2002520049A
Authority: JP; Japan
Prior art keywords: conjugate; polypeptide; enzyme; molecular weight; parent
Prior art date: 1998-07-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP2000560236A

Other languages

English (en)

Japanese (ja)

Inventor

バウディツ，ペーター

ムクソルファトゥム，ティネ

アゲルリンオルセン，アルネ

デウセン，ハインツ−ヨセフ

アービーペテルセン，ドルテ

Original Assignee

ノボザイムスアクティーゼルスカブ

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-17

Filing date

1999-07-16

Publication date

2002-07-09

1999-07-16 Application filed by ノボザイムスアクティーゼルスカブ filed Critical ノボザイムスアクティーゼルスカブ

2002-07-09 Publication of JP2002520049A publication Critical patent/JP2002520049A/ja

Status Pending legal-status Critical Current

Links

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235000010335 lysozyme Nutrition 0.000 description 1
229910052749 magnesium Inorganic materials 0.000 description 1
239000011777 magnesium Substances 0.000 description 1
230000000873 masking effect Effects 0.000 description 1
238000005259 measurement Methods 0.000 description 1
239000002609 medium Substances 0.000 description 1
239000012528 membrane Substances 0.000 description 1
108010003855 mesentericopeptidase Proteins 0.000 description 1
229910021645 metal ion Inorganic materials 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
239000000693 micelle Substances 0.000 description 1
108010009355 microbial metalloproteinases Proteins 0.000 description 1
244000000010 microbial pathogen Species 0.000 description 1
239000003607 modifier Substances 0.000 description 1
230000003020 moisturizing effect Effects 0.000 description 1
238000010172 mouse model Methods 0.000 description 1
239000002324 mouth wash Substances 0.000 description 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
230000000269 nucleophilic effect Effects 0.000 description 1
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical class CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
239000013307 optical fiber Substances 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
230000001590 oxidative effect Effects 0.000 description 1
150000002924 oxiranes Chemical class 0.000 description 1
229940055729 papain Drugs 0.000 description 1
235000019834 papain Nutrition 0.000 description 1
239000006072 paste Substances 0.000 description 1
229960000292 pectin Drugs 0.000 description 1
229940100460 peg-100 stearate Drugs 0.000 description 1
JLFNLZLINWHATN-UHFFFAOYSA-N pentaethylene glycol Chemical compound OCCOCCOCCOCCOCCO JLFNLZLINWHATN-UHFFFAOYSA-N 0.000 description 1
239000000813 peptide hormone Substances 0.000 description 1
235000020030 perry Nutrition 0.000 description 1
239000000575 pesticide Substances 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
239000010452 phosphate Substances 0.000 description 1
229910052698 phosphorus Inorganic materials 0.000 description 1
239000011574 phosphorus Substances 0.000 description 1
230000001766 physiological effect Effects 0.000 description 1
235000002949 phytic acid Nutrition 0.000 description 1
239000000049 pigment Substances 0.000 description 1
238000005498 polishing Methods 0.000 description 1
229920001983 poloxamer Polymers 0.000 description 1
108010004131 poly(beta-D-mannuronate) lyase Proteins 0.000 description 1
229920002401 polyacrylamide Polymers 0.000 description 1
229920001515 polyalkylene glycol Polymers 0.000 description 1
229920000768 polyamine Polymers 0.000 description 1
229920005646 polycarboxylate Polymers 0.000 description 1
229920002523 polyethylene Glycol 1000 Polymers 0.000 description 1
229920005862 polyol Polymers 0.000 description 1
150000003077 polyols Chemical class 0.000 description 1
229920000056 polyoxyethylene ether Polymers 0.000 description 1
229940051841 polyoxyethylene ether Drugs 0.000 description 1
150000004804 polysaccharides Chemical class 0.000 description 1
IFIDXBCRSWOUSB-UHFFFAOYSA-N potassium;1,3-dichloro-1,3,5-triazinane-2,4,6-trione Chemical compound [K+].ClN1C(=O)NC(=O)N(Cl)C1=O IFIDXBCRSWOUSB-UHFFFAOYSA-N 0.000 description 1
239000000843 powder Substances 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
238000002203 pretreatment Methods 0.000 description 1
230000008569 process Effects 0.000 description 1
108010017378 prolyl aminopeptidase Proteins 0.000 description 1
125000002572 propoxy group Chemical group [*]OC([H])([H])C(C([H])([H])[H])([H])[H] 0.000 description 1
235000013772 propylene glycol Nutrition 0.000 description 1
235000019833 protease Nutrition 0.000 description 1
239000011241 protective layer Substances 0.000 description 1
229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 1
125000000714 pyrimidinyl group Chemical group 0.000 description 1
238000000197 pyrolysis Methods 0.000 description 1
239000002516 radical scavenger Substances 0.000 description 1
230000009257 reactivity Effects 0.000 description 1
230000009467 reduction Effects 0.000 description 1
238000002310 reflectometry Methods 0.000 description 1
210000003296 saliva Anatomy 0.000 description 1
238000003118 sandwich ELISA Methods 0.000 description 1
238000009991 scouring Methods 0.000 description 1
210000002374 sebum Anatomy 0.000 description 1
125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
238000000926 separation method Methods 0.000 description 1
150000004760 silicates Chemical class 0.000 description 1
229910052709 silver Inorganic materials 0.000 description 1
239000004332 silver Substances 0.000 description 1
210000004927 skin cell Anatomy 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
MWNQXXOSWHCCOZ-UHFFFAOYSA-L sodium;oxido carbonate Chemical compound [Na+].[O-]OC([O-])=O MWNQXXOSWHCCOZ-UHFFFAOYSA-L 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1
239000012086 standard solution Substances 0.000 description 1
230000000638 stimulation Effects 0.000 description 1
239000004575 stone Substances 0.000 description 1
239000012089 stop solution Substances 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
229940014800 succinic anhydride Drugs 0.000 description 1
238000006277 sulfonation reaction Methods 0.000 description 1
YBBRCQOCSYXUOC-UHFFFAOYSA-N sulfuryl dichloride Chemical class ClS(Cl)(=O)=O YBBRCQOCSYXUOC-UHFFFAOYSA-N 0.000 description 1
239000000375 suspending agent Substances 0.000 description 1
229950009390 symclosene Drugs 0.000 description 1
230000002195 synergetic effect Effects 0.000 description 1
230000009897 systematic effect Effects 0.000 description 1
230000001839 systemic circulation Effects 0.000 description 1
QEMXHQIAXOOASZ-UHFFFAOYSA-N tetramethylammonium Chemical compound C[N+](C)(C)C QEMXHQIAXOOASZ-UHFFFAOYSA-N 0.000 description 1
150000003573 thiols Chemical group 0.000 description 1
150000003585 thioureas Chemical class 0.000 description 1
231100000027 toxicology Toxicity 0.000 description 1
238000006276 transfer reaction Methods 0.000 description 1
150000003626 triacylglycerols Chemical class 0.000 description 1
ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
JLGLQAWTXXGVEM-UHFFFAOYSA-N triethylene glycol monomethyl ether Chemical compound COCCOCCOCCO JLGLQAWTXXGVEM-UHFFFAOYSA-N 0.000 description 1
230000001960 triggered effect Effects 0.000 description 1
229960004418 trolamine Drugs 0.000 description 1
150000003672 ureas Chemical class 0.000 description 1
238000012795 verification Methods 0.000 description 1
239000003643 water by type Substances 0.000 description 1
229920003169 water-soluble polymer Polymers 0.000 description 1
230000003313 weakening effect Effects 0.000 description 1
238000009941 weaving Methods 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1
230000002087 whitening effect Effects 0.000 description 1
108010078692 yeast proteinase B Proteins 0.000 description 1
239000010457 zeolite Substances 0.000 description 1
239000002888 zwitterionic surfactant Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/3707—Polyethers, e.g. polyalkyleneoxides
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Enzymes And Modification Thereof (AREA)
Detergent Compositions (AREA)
Compositions Of Macromolecular Compounds (AREA)
Polyethers (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

JP2000560236A 1998-07-17 1999-07-16 改良された洗浄性能を有するポリペプチド−ポリマー接合体 Pending JP2002520049A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DKPA199800951		1998-07-17
DK199800951		1998-07-17
PCT/DK1999/000406 WO2000004138A1 (en)	1998-07-17	1999-07-16	A polypeptide-polymer conjugate with improved wash performance

Publications (1)

Publication Number	Publication Date
JP2002520049A true JP2002520049A (ja)	2002-07-09

Family

ID=8099345

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2000560236A Pending JP2002520049A (ja)	1998-07-17	1999-07-16	改良された洗浄性能を有するポリペプチド−ポリマー接合体

Country Status (9)

Country	Link
EP (1)	EP1098964A1 (pt)
JP (1)	JP2002520049A (pt)
KR (1)	KR20010079542A (pt)
CN (1)	CN1315997A (pt)
AU (1)	AU770911B2 (pt)
BR (1)	BR9912158A (pt)
CA (1)	CA2333491A1 (pt)
MX (1)	MXPA01000556A (pt)
WO (1)	WO2000004138A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2006094811A (ja) *	2004-09-30	2006-04-13	Tokyo Institute Of Technology	修飾ラッカーゼおよび芳香族化合物の処理方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2001268953A1 (en) *	2000-07-21	2002-02-05	Novozymes A/S	Antimicrobial compositions
AU2002345938A1 (en) *	2001-06-28	2003-03-03	Mountain View Pharmaceuticals, Inc.	Polymer stabilized proteinases
CN105200027B (zh) *	2005-10-12	2019-05-31	金克克国际有限公司	储存稳定的中性金属蛋白酶的用途和制备
CN100365043C (zh) *	2006-04-06	2008-01-30	北京理工大学	ABA型聚肽-b-聚四氢呋喃-b-聚肽三嵌段共聚物的合成
EP2075331A1 (en) *	2007-12-28	2009-07-01	Qiagen GmbH	Modified enzymes and their uses
BR112014003419B1 (pt) *	2011-08-24	2020-06-23	Unilever N.V	Partícula e composição
EP2748297B1 (en) *	2011-08-24	2021-01-20	Unilever N.V.	Improvements relating to polymers, deposition aids, targeted benefit agents and substrate treatment compositions
DE102015201702A1 (de) *	2015-01-30	2016-08-04	Henkel Ag & Co. Kgaa	Saures Flüssigkompaktwaschmittel enthaltend Hydroxycarbonsäure, Niotensid und Enzym
WO2019143578A1 (en) *	2018-01-17	2019-07-25	The Regents Of The University Of California	Random heteropolymers preserve protein function in foreign environments
CN108823196B (zh) *	2018-06-21	2022-01-18	湖州师范学院	一种高载量固定化扁桃酸消旋酶的制备方法
EP4273210A1 (en) *	2022-05-04	2023-11-08	The Procter & Gamble Company	Detergent compositions containing enzymes
EP4273209A1 (en) *	2022-05-04	2023-11-08	The Procter & Gamble Company	Machine-cleaning compositions containing enzymes

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Publication number	Priority date	Publication date	Assignee	Title
IE64284B1 (en) *	1987-08-03	1995-07-26	Ddi Pharmaceuticals	Conjugates of superoxide dismutase
EP0675727B1 (en) *	1992-12-10	2002-04-10	Enzon, Inc.	Glycolipid enzyme-polymer conjugates
FI972443A0 (fi) *	1994-12-07	1997-06-09	Novo Nordisk As	Polypeptidi, jonka allergeenisuus on vähentynyt
WO1996040792A1 (en) *	1995-06-07	1996-12-19	Novo Nordisk A/S	Modification of polypeptides
WO1997024421A2 (en) *	1995-12-29	1997-07-10	The Procter & Gamble Company	Detergent compositions comprising immobilized enzymes
CN1273589C (zh) *	1996-02-15	2006-09-06	诺沃奇梅兹有限公司	多肽缀合

1999
- 1999-07-16 CN CN99810440A patent/CN1315997A/zh active Pending
- 1999-07-16 EP EP99932687A patent/EP1098964A1/en not_active Withdrawn
- 1999-07-16 WO PCT/DK1999/000406 patent/WO2000004138A1/en not_active Ceased
- 1999-07-16 JP JP2000560236A patent/JP2002520049A/ja active Pending
- 1999-07-16 BR BR9912158-1A patent/BR9912158A/pt not_active IP Right Cessation
- 1999-07-16 AU AU48983/99A patent/AU770911B2/en not_active Ceased
- 1999-07-16 MX MXPA01000556A patent/MXPA01000556A/es unknown
- 1999-07-16 KR KR1020017000757A patent/KR20010079542A/ko not_active Withdrawn
- 1999-07-16 CA CA002333491A patent/CA2333491A1/en not_active Abandoned

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2006094811A (ja) *	2004-09-30	2006-04-13	Tokyo Institute Of Technology	修飾ラッカーゼおよび芳香族化合物の処理方法

Also Published As

Publication number	Publication date
MXPA01000556A (es)	2002-05-14
AU770911B2 (en)	2004-03-04
WO2000004138A1 (en)	2000-01-27
BR9912158A (pt)	2001-04-10
CA2333491A1 (en)	2000-01-27
CN1315997A (zh)	2001-10-03
EP1098964A1 (en)	2001-05-16
AU4898399A (en)	2000-02-07
KR20010079542A (ko)	2001-08-22

Publication	Publication Date	Title
AU697440B2 (en)	1998-10-08	Polypeptide with reduced allergenicity
ES2296336T3 (es)	2008-04-16	Polipeptido modificado.
AU736806B2 (en)	2001-08-02	A modified enzyme for skin care
ES2220114T3 (es)	2004-12-01	Variantes de proteinas poco alergenicas.
WO1996040791A1 (en)	1996-12-19	Modification of polypeptides
JP2001511162A (ja)	2001-08-07	付加され、そして／又は除去された付着基を有するポリペプチド−ポリマー結合体
JP2002520049A (ja)	2002-07-09	改良された洗浄性能を有するポリペプチド−ポリマー接合体
US6461849B1 (en)	2002-10-08	Modified polypeptide
EP1088059B1 (en)	2004-09-15	A polypeptide-polymer conjugate
US6416756B1 (en)	2002-07-09	Modified protease having 5 to 13 covalently coupled polymeric molecules for skin care
CZ2002171A3 (cs)	2002-06-12	Proteinázový konjugát, čistící prostředek a prostředek osobní péče
US6638526B1 (en)	2003-10-28	Polypeptides conjugated to copolymers of ethylene oxide and propylene oxide to reduce allergenicity
AU731076B2 (en)	2001-03-22	Composition comprising polypeptide with reduced allergenicity

JP2002520049A - 改良された洗浄性能を有するポリペプチド−ポリマー接合体 - Google Patents

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Landscapes

Applications Claiming Priority (3)

Publications (1)

Family

ID=8099345

Family Applications (1)

Country Status (9)

Cited By (1)

Families Citing this family (12)

Family Cites Families (6)

Cited By (1)

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