[go: up one dir, main page]

JOP20200058A1 - تصنيع تركيبات صيدلانية - Google Patents

تصنيع تركيبات صيدلانية

Info

Publication number
JOP20200058A1
JOP20200058A1 JOP/2020/0058A JOP20200058A JOP20200058A1 JO P20200058 A1 JOP20200058 A1 JO P20200058A1 JO P20200058 A JOP20200058 A JO P20200058A JO P20200058 A1 JOP20200058 A1 JO P20200058A1
Authority
JO
Jordan
Prior art keywords
manufacturing
pharmaceutical compositions
mixing
pharmaceutical composition
vehicle
Prior art date
Application number
JOP/2020/0058A
Other languages
English (en)
Inventor
Josselin Saunier
Robert Ronnback
Original Assignee
Ferring Int Center Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Int Center Sa filed Critical Ferring Int Center Sa
Publication of JOP20200058A1 publication Critical patent/JOP20200058A1/ar

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/02—Maintaining the aggregation state of the mixed materials
    • B01F23/024—Maintaining mixed ingredients in movement to prevent separation of the ingredients after mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/06—Mixing phases by adding a very small quantity of one of the phases or microdosing
    • B01F23/062—Mixing ingredients in very small quantity, adding microingredients or microconcentration, e.g. adding vitamins, minerals, proteins, enzymes, hormones, antibiotics or worm medicines
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/114—Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections
    • B01F27/1143—Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections screw-shaped, e.g. worms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/60—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis
    • B01F27/72—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis with helices or sections of helices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/82—Combinations of dissimilar mixers
    • B01F33/821—Combinations of dissimilar mixers with consecutive receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/84—Mixing plants with mixing receptacles receiving material dispensed from several component receptacles, e.g. paint tins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/211—Measuring of the operational parameters
    • B01F35/2111—Flow rate
    • B01F35/21111—Mass flow rate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/211—Measuring of the operational parameters
    • B01F35/2117—Weight
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/2132—Concentration, pH, pOH, p(ION) or oxygen-demand
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/2135—Humidity, e.g. moisture content
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/214—Measuring characterised by the means for measuring
    • B01F35/2144—Measuring characterised by the means for measuring using radiation for measuring the parameters of the mixture or components to be mixed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/22—Control or regulation
    • B01F35/2201—Control or regulation characterised by the type of control technique used
    • B01F35/2203—Controlling the mixing process by feed-forward, i.e. a parameter of the components to be mixed is measured and the feed values are calculated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/715—Feeding the components in several steps, e.g. successive steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/82—Forming a predetermined ratio of the substances to be mixed by adding a material to be mixed to a mixture in response to a detected feature, e.g. density, radioactivity, consumed power or colour
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Medical Informatics (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Accessories For Mixers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

غير متوفر
JOP/2020/0058A 2017-09-18 2019-03-18 تصنيع تركيبات صيدلانية JOP20200058A1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17191652 2017-09-18

Publications (1)

Publication Number Publication Date
JOP20200058A1 true JOP20200058A1 (ar) 2020-03-11

Family

ID=59914324

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2020/0058A JOP20200058A1 (ar) 2017-09-18 2019-03-18 تصنيع تركيبات صيدلانية

Country Status (21)

Country Link
US (1) US12263246B2 (ar)
EP (1) EP3684335A1 (ar)
JP (1) JP7291127B2 (ar)
KR (1) KR102586260B1 (ar)
CN (1) CN111372571B (ar)
AR (1) AR112818A1 (ar)
AU (1) AU2018332076B2 (ar)
BR (1) BR112020004952A2 (ar)
CL (1) CL2020000643A1 (ar)
CO (1) CO2020002904A2 (ar)
EA (1) EA039921B1 (ar)
IL (1) IL273259B2 (ar)
JO (1) JOP20200058A1 (ar)
MX (1) MX2020002779A (ar)
PH (1) PH12020500525A1 (ar)
SG (1) SG11202002168SA (ar)
TN (1) TN2020000047A1 (ar)
TW (1) TWI775943B (ar)
UA (1) UA127186C2 (ar)
WO (1) WO2019053247A1 (ar)
ZA (1) ZA202001544B (ar)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220100934A (ko) 2019-11-15 2022-07-18 론자 리미티드 접종물을 제조하기 위한 공정 및 시스템
US12145112B2 (en) * 2020-11-04 2024-11-19 Saudi Arabian Oil Company Methods and systems for the generation of stable oil-in-water or water-in-oil emulsion for enhanced oil recovery
CN112569848B (zh) * 2020-12-16 2022-11-15 安徽惠泽农业科技有限公司 一种多组份复合肥调制处理装置及复合肥生产工艺
US11583876B2 (en) * 2021-03-15 2023-02-21 The Boeing Company Positive displacement end effector with multiple cartridges
US11850619B2 (en) * 2021-03-15 2023-12-26 The Boeing Company Robot end effector for dispensing an extrudable substance
US11583886B2 (en) * 2021-03-15 2023-02-21 The Boeing Company Robot end effector with rotating barrel for dispensing an extrudable substance
IL320064A (en) * 2022-10-07 2025-06-01 Genzyme Corp Product formulation in biological production

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3034046A (en) * 1959-10-12 1962-05-08 Sasaki Shinichi Automatic moisture content determination and control apparatus
US3644826A (en) * 1967-04-03 1972-02-22 Industrial Nucleonics Corp Moisture-measuring system using microwave and nucleonic measurements
US5302394A (en) * 1992-07-14 1994-04-12 Mcneil-Ppc, Inc. Dextromethorphan continuous lozenge manufacturing process
US5350234A (en) 1994-01-21 1994-09-27 Dow Corning Corporation Process for continuously mixing two or more materials with non-pulsating mixing and filling storage containers
SE506791C2 (sv) * 1996-06-03 1998-02-09 Arom Pak Ab Doseringsanordning för att med ett kontinuerligt förfarande blanda en strömmande primärvätska med en eller flera tillförda sekundärvätskor samt sätt att sammanblanda två eller flera vätskor
KR100491522B1 (ko) * 1996-06-03 2005-08-04 테트라 라발 홀딩즈 앤드 파이낸스 소시에떼 아노님 유동성제1액체를 한가지 이상의제2액체와 연속공정으로 혼합시키는 계량공급장치
JPH10337459A (ja) 1997-06-06 1998-12-22 Taiyo Techno Kk 流動体の混合方法及び装置
CN1251662C (zh) * 2003-01-29 2006-04-19 中山大学 一种中药提取液的低温浓缩方法及其装置
US8271139B2 (en) * 2003-10-17 2012-09-18 Asahi Kasei Bioprocess, Inc. Multi-stage accurate blending system and method
CA2466799C (en) 2004-05-07 2011-10-18 Oden Corporation An improved continuous liquid stream blender
GB0416694D0 (en) * 2004-07-27 2004-09-01 Univ Strathclyde Process for preparing microcrystals
US8746959B2 (en) * 2007-07-26 2014-06-10 Ganado Technologies Corp. Apparatus and method to feed livestock
KR20110003383A (ko) * 2008-04-30 2011-01-11 노파르티스 아게 제약 조성물의 연속 제조 방법
DE102010037516B4 (de) * 2010-09-14 2012-05-24 Chocotech Gmbh Verfahren und Vorrichtung zur energiesparenden Herstellung von Süßwarenmassen
WO2012128603A1 (fr) 2011-03-22 2012-09-27 Aouad Salah Mohammed Dispositif automatique et procede de preparation de solutions
CN202777089U (zh) * 2012-09-21 2013-03-13 南京中医药大学 一种中药多功能提取、精制、浓缩设备
CN105075457B (zh) 2014-05-05 2017-11-17 中国农业机械化科学研究院 一种种子包衣机及其种药协同在线控制装置和方法
CN105686032B (zh) 2016-01-20 2018-03-30 宜诺（天津）科技有限公司 一种荸荠包衣锅自动化联线生产的方法
PT109117B (pt) * 2016-01-28 2019-02-01 Hovione Farm Sa Complexação de ingredientes ativos farmacêuticos
SG11201807521WA (en) * 2016-03-11 2018-09-27 Fujifilm Planar Solutions Llc Advanced fluid processing methods and systems

Also Published As

Publication number Publication date
IL273259A (en) 2020-04-30
EP3684335A1 (en) 2020-07-29
CA3075689A1 (en) 2019-03-21
JP2020534288A (ja) 2020-11-26
MX2020002779A (es) 2020-11-06
TW201919557A (zh) 2019-06-01
WO2019053247A1 (en) 2019-03-21
EA039921B1 (ru) 2022-03-28
US20200222319A1 (en) 2020-07-16
CL2020000643A1 (es) 2020-09-11
AR112818A1 (es) 2019-12-18
PH12020500525A1 (en) 2021-05-10
US12263246B2 (en) 2025-04-01
BR112020004952A2 (pt) 2020-09-15
UA127186C2 (uk) 2023-05-31
SG11202002168SA (en) 2020-04-29
AU2018332076B2 (en) 2024-10-17
EA202090508A1 (ru) 2020-07-06
CN111372571B (zh) 2022-11-18
IL273259B2 (en) 2025-03-01
TWI775943B (zh) 2022-09-01
AU2018332076A1 (en) 2020-04-02
KR102586260B1 (ko) 2023-10-06
JP7291127B2 (ja) 2023-06-14
ZA202001544B (en) 2021-10-27
CO2020002904A2 (es) 2020-05-29
CN111372571A (zh) 2020-07-03
TN2020000047A1 (en) 2021-10-04
KR20200065002A (ko) 2020-06-08
IL273259B1 (en) 2024-11-01

Similar Documents

Publication Publication Date Title
PH12020500525A1 (en) Manufacturing of pharmaceutical compositions
PH12017502246A1 (en) New hydroxyester derivatives, a process for their preparation and pharmaceutical compositions containing them
PH12017502315B1 (en) New bicyclic derivatives, a process for their preparation and pharmaceutical compositions containing them
PH12017502266A1 (en) New aminoacid derivatives, a process for their preparation and pharmaceutical compositions containing them
PH12016500094A1 (en) Autotaxin inhibitors
IL255509B (en) Compounds as modulators of ccr2, pharmaceutical preparations containing them and their use in the treatment of diseases
MY193728A (en) Muscarinic receptor agonists
PH12018500586A1 (en) Farnesoid x receptor agonists and uses thereof
MY196328A (en) New (Hetero)Aryl-Substituted-Piperidinyl Derivatives, A Process For Their Preparation And Pharmaceutical Compositions Containing Them
PH12016501570A1 (en) Bicyclic aza compounds as muscarinic m1 receptor and/or m4 receptor agonists
PH12017500810A1 (en) Substituted 2,4 diamino-quinoline as new anticancer agents
TW201613864A (en) Novel compounds
MX2017006513A (es) Compuestos de tipo 1,9-diazaespiroundecano con actividad multimodal contra el dolor.
MX2018010065A (es) Forma de dosificacion oral que comprende rifaximina en forma beta.
PH12019500992A1 (en) Directly tablettable matrix for producing tablets with extended active substance delivery
PH12019501820A1 (en) Pharmaceutical compositions for combination therapy
MX2018000418A (es) Derivados de amida que tienen actividad multimodal contra el dolor.
MX2016013711A (es) Antagonistas de receptores de glumato metabotropicos 2/3 (mglu2/3) para el tratamiento de varias discapacidades intelectuales.
GB2519470A (en) Bicyclic aza compounds as muscarinic M1 receptor agonists
PH12015000067B1 (en) Ulasimang bato(peperomia pellucida) tablet as anti-hyperuricemic agent
MX390164B (es) Composición farmacéutica de loratadina-fenilefrina para integrar una capsula, para el tratamiento de resfriados entre otras alopatías.
MY176807A (en) Novel indazole compounds and a process for the preparation thereof