JO921B1 - Process for the production of basic substituted alkyl theophylline - Google Patents
Process for the production of basic substituted alkyl theophyllineInfo
- Publication number
- JO921B1 JO921B1 JO1978921A JOP19780921A JO921B1 JO 921 B1 JO921 B1 JO 921B1 JO 1978921 A JO1978921 A JO 1978921A JO P19780921 A JOP19780921 A JO P19780921A JO 921 B1 JO921 B1 JO 921B1
- Authority
- JO
- Jordan
- Prior art keywords
- formula
- carbon atoms
- substituted alkyl
- production
- basic substituted
- Prior art date
Links
- -1 substituted alkyl theophylline Chemical compound 0.000 title abstract 2
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N Theophylline Natural products O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 title 1
- 229960000278 theophylline Drugs 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Abstract of US 4150227 (A) Basic substituted alkyl theophylline derivatives of the formula (I) in which Alk is a straight or branched chain alkylene group with 2 to 4 carbon atoms and R is hydrogen or a methyl group are produced by catalytic hydrogenation of compounds of the formula (II) where the phenolic hydroxyl groups and/or the secondary basic nitrogen atom can contain protective groups using as the solvent a compound of the formula (III) where R', R'' and R''' are the same or different and are alkyl groups of 1 to 2 carbon atoms and R' together with R''' can also be an alkylene bridge with 3 to 4 carbon atoms and in a given case the protective groups present are split off.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JO1978921A JO921B1 (en) | 1978-02-06 | 1978-02-06 | Process for the production of basic substituted alkyl theophylline |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JO1978921A JO921B1 (en) | 1978-02-06 | 1978-02-06 | Process for the production of basic substituted alkyl theophylline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO921B1 true JO921B1 (en) | 1978-09-30 |
Family
ID=48086987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JO1978921A JO921B1 (en) | 1978-02-06 | 1978-02-06 | Process for the production of basic substituted alkyl theophylline |
Country Status (1)
| Country | Link |
|---|---|
| JO (1) | JO921B1 (en) |
-
1978
- 1978-02-06 JO JO1978921A patent/JO921B1/en active
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