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IT1298155B1 - Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della - Google Patents

Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della

Info

Publication number
IT1298155B1
IT1298155B1 ITMI980086A IT1298155B1 IT 1298155 B1 IT1298155 B1 IT 1298155B1 IT MI980086 A ITMI980086 A IT MI980086A IT 1298155 B1 IT1298155 B1 IT 1298155B1
Authority
IT
Italy
Prior art keywords
treatment
pyridid
muscle
oxide compounds
skeletal pathologies
Prior art date
Application number
Other languages
English (en)
Inventor
Moreno Paolini
Domenico Tricarico
Original Assignee
Moreno Paolini
Domenico Tricarico
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moreno Paolini, Domenico Tricarico filed Critical Moreno Paolini
Priority to ITMI980086 priority Critical patent/IT1298155B1/it
Priority to PCT/EP1999/000269 priority patent/WO1999036072A1/en
Priority to EP99904793A priority patent/EP1049473A1/en
Publication of ITMI980086A1 publication Critical patent/ITMI980086A1/it
Application granted granted Critical
Publication of IT1298155B1 publication Critical patent/IT1298155B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ITMI980086 1998-01-19 1998-01-19 Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della IT1298155B1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITMI980086 IT1298155B1 (it) 1998-01-19 1998-01-19 Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della
PCT/EP1999/000269 WO1999036072A1 (en) 1998-01-19 1999-01-18 Pyrimidin 3-oxide compounds suitable for the treatment of pathologies of the skeletal muscle, in particular for the treatment of the hypokalemic paralysis
EP99904793A EP1049473A1 (en) 1998-01-19 1999-01-18 Pyrimidin 3-oxide compounds suitable for the treatment of pathologies of the skeletal muscle, in particular for the treatment of the hypokalemic paralysis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI980086 IT1298155B1 (it) 1998-01-19 1998-01-19 Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della

Publications (2)

Publication Number Publication Date
ITMI980086A1 ITMI980086A1 (it) 1999-07-19
IT1298155B1 true IT1298155B1 (it) 1999-12-20

Family

ID=11378623

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI980086 IT1298155B1 (it) 1998-01-19 1998-01-19 Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della

Country Status (3)

Country Link
EP (1) EP1049473A1 (it)
IT (1) IT1298155B1 (it)
WO (1) WO1999036072A1 (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1323432B1 (en) * 2001-12-28 2005-08-24 Sandra Cosci Complexes of cyclodextrins with potassium ion homeostasis regulators
TWI417095B (zh) 2006-03-15 2013-12-01 Janssen Pharmaceuticals Inc １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
CN101801951B (zh) 2007-09-14 2013-11-13 杨森制药有限公司 1’,3’-二取代的-4-苯基-3,4,5,6-四氢-2h,1’h-[1,4’]二吡啶-2’-酮
US8691849B2 (en) 2008-09-02 2014-04-08 Janssen Pharmaceuticals, Inc. 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
CA2744138C (en) 2008-11-28 2015-08-11 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
US8946205B2 (en) 2009-05-12 2015-02-03 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
HRP20131122T1 (hr) 2009-05-12 2013-12-20 Janssen Pharmaceuticals, Inc. Derivati 1,2,4-triazolo[4,3-a] piridina i njihova uporaba u lijeäśenju ili prevenciji neuroloških i psihijatrijskih poremeä†aja
ES2552455T3 (es) 2010-11-08 2015-11-30 Janssen Pharmaceuticals, Inc. Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
WO2012062759A1 (en) 2010-11-08 2012-05-18 Janssen Pharmaceuticals, Inc. 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
US9012448B2 (en) 2010-11-08 2015-04-21 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
MY204637A (en) 2014-01-21 2024-09-06 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
KR20200126026A (ko) 2014-01-21 2020-11-05 얀센 파마슈티카 엔.브이. 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2055376A1 (en) * 1990-12-05 1992-06-06 Gary J. Grover Method of treating shock using a potassium channel activator

Also Published As

Publication number Publication date
EP1049473A1 (en) 2000-11-08
WO1999036072A1 (en) 1999-07-22
ITMI980086A1 (it) 1999-07-19

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