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IT1276031B1 - Composizione farmaceutica per il trattamento delle malattie autoimmuni - Google Patents

Composizione farmaceutica per il trattamento delle malattie autoimmuni

Info

Publication number
IT1276031B1
IT1276031B1 IT95MI002242A ITMI952242A IT1276031B1 IT 1276031 B1 IT1276031 B1 IT 1276031B1 IT 95MI002242 A IT95MI002242 A IT 95MI002242A IT MI952242 A ITMI952242 A IT MI952242A IT 1276031 B1 IT1276031 B1 IT 1276031B1
Authority
IT
Italy
Prior art keywords
pharmaceutical composition
pct
treatment
autoimmune diseases
date
Prior art date
Application number
IT95MI002242A
Other languages
English (en)
Inventor
Angelo Guglielmotti
Paolo Dionisio
Original Assignee
Angelini Ricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11372453&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1276031(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Angelini Ricerche Spa filed Critical Angelini Ricerche Spa
Priority to IT95MI002242A priority Critical patent/IT1276031B1/it
Publication of ITMI952242A0 publication Critical patent/ITMI952242A0/it
Priority to HU9901303A priority patent/HU228051B1/hu
Priority to JP51705397A priority patent/JP4007615B2/ja
Priority to CA002236256A priority patent/CA2236256C/en
Priority to AU74938/96A priority patent/AU721841B2/en
Priority to AT96937258T priority patent/ATE326965T1/de
Priority to PT96937258T priority patent/PT858337E/pt
Priority to US09/068,011 priority patent/US6020356A/en
Priority to PCT/EP1996/004672 priority patent/WO1997016185A2/en
Priority to CNB96199472XA priority patent/CN1229113C/zh
Priority to DE69636167T priority patent/DE69636167T2/de
Priority to KR1019980703195A priority patent/KR19990067237A/ko
Priority to SI9630737T priority patent/SI0858337T1/sl
Priority to DK96937258T priority patent/DK0858337T3/da
Priority to IL12429196A priority patent/IL124291A/en
Priority to BRPI9611320-0A priority patent/BR9611320B1/pt
Priority to EA199800417A priority patent/EA000826B1/ru
Priority to SK579-98A priority patent/SK284069B6/sk
Priority to ES96937258T priority patent/ES2264144T3/es
Priority to CZ19981326A priority patent/CZ292258B6/cs
Priority to TR1998/00765T priority patent/TR199800765T2/xx
Priority to EP96937258A priority patent/EP0858337B1/en
Priority to PL96326371A priority patent/PL186377B1/pl
Priority to NZ321580A priority patent/NZ321580A/en
Priority to HK99103337.8A priority patent/HK1018219B/xx
Priority to ZA969060A priority patent/ZA969060B/xx
Publication of ITMI952242A1 publication Critical patent/ITMI952242A1/it
Publication of IT1276031B1 publication Critical patent/IT1276031B1/it
Application granted granted Critical
Priority to NO19981951A priority patent/NO324130B1/no
Priority to MX9803478A priority patent/MX9803478A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT95MI002242A 1995-10-31 1995-10-31 Composizione farmaceutica per il trattamento delle malattie autoimmuni IT1276031B1 (it)

Priority Applications (28)

Application Number Priority Date Filing Date Title
IT95MI002242A IT1276031B1 (it) 1995-10-31 1995-10-31 Composizione farmaceutica per il trattamento delle malattie autoimmuni
HK99103337.8A HK1018219B (en) 1995-10-31 1996-10-26 A pharmaceutical composition for the treatment of autoimmune diseases
DK96937258T DK0858337T3 (da) 1995-10-31 1996-10-26 Farmaceutisk præparat til behandling af autoimmune sygdomme
EA199800417A EA000826B1 (ru) 1995-10-31 1996-10-26 Фармацевтическая композиция для лечения аутоиммунных заболеваний
CA002236256A CA2236256C (en) 1995-10-31 1996-10-26 A pharmaceutical composition for the treatment of autoimmune diseases
AU74938/96A AU721841B2 (en) 1995-10-31 1996-10-26 A pharmaceutical composition for the treatment of autoimmune diseases
AT96937258T ATE326965T1 (de) 1995-10-31 1996-10-26 Pharmazeutische zusammensetzung zur behandlung von autoimmunkrankheiten
PT96937258T PT858337E (pt) 1995-10-31 1996-10-26 Composicao farmaceutica para o tratamento de doencas auto-imunes
US09/068,011 US6020356A (en) 1995-10-31 1996-10-26 Pharmaceutical composition for the treatment of autoimmune diseases
PCT/EP1996/004672 WO1997016185A2 (en) 1995-10-31 1996-10-26 A pharmaceutical composition for the treatment of autoimmune diseases
CNB96199472XA CN1229113C (zh) 1995-10-31 1996-10-26 用于治疗自身免疫性疾病的药物组合物
DE69636167T DE69636167T2 (de) 1995-10-31 1996-10-26 Pharmazeutische zusammensetzung zur behandlung von autoimmunkrankheiten
KR1019980703195A KR19990067237A (ko) 1995-10-31 1996-10-26 자기면역질환 치료용 제약학적 조성물
SI9630737T SI0858337T1 (sl) 1995-10-31 1996-10-26 Farmacevtski sestavek za zdravljenje avtoimunskihbolezni
HU9901303A HU228051B1 (en) 1995-10-31 1996-10-26 A pharmaceutical composition for the treatment of autoimmune diseases
IL12429196A IL124291A (en) 1995-10-31 1996-10-26 Pharmaceutical preparations containing bindrite and immunosuppressant for the treatment of autoimmune diseases
BRPI9611320-0A BR9611320B1 (pt) 1995-10-31 1996-10-26 composição farmacêutica compreendendo bidarit, um imunossurpressor selecionado a partir de ciclofosfamida, metilprednisolona, prednisolona e prednisona.
JP51705397A JP4007615B2 (ja) 1995-10-31 1996-10-26 自己免疫性疾患の処置用薬剤組成物
SK579-98A SK284069B6 (sk) 1995-10-31 1996-10-26 Farmaceutický prípravok na liečenie autoimunitných patologických stavov
ES96937258T ES2264144T3 (es) 1995-10-31 1996-10-26 Composicion farmaceutica para el tratameinto de enfermedades autoinmunes.
CZ19981326A CZ292258B6 (cs) 1995-10-31 1996-10-26 Farmaceutický prostředek pro léčení autoimunních chorob
TR1998/00765T TR199800765T2 (xx) 1995-10-31 1996-10-26 Otoim�n hastal�klar�n tedavisine mahsus bir farmas�tik bile�im
EP96937258A EP0858337B1 (en) 1995-10-31 1996-10-26 A pharmaceutical composition for the treatment of autoimmune diseases
PL96326371A PL186377B1 (pl) 1995-10-31 1996-10-26 Kompozycja farmaceutyczna do leczenia chorób autoimmunologicznych
NZ321580A NZ321580A (en) 1995-10-31 1996-10-26 A pharmaceutical composition containing bindarit for the treatment of autoimmune diseases
ZA969060A ZA969060B (en) 1995-10-31 1996-10-28 A pharmaceutical composition for the treatment of autoimmune diseases
NO19981951A NO324130B1 (no) 1995-10-31 1998-04-29 Farmasoytisk preparat for behandling av autoimmunsykdommer
MX9803478A MX9803478A (es) 1995-10-31 1998-04-30 Una composicion farmaceutica para el tratamiento de enfermedades autoinmunes.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI002242A IT1276031B1 (it) 1995-10-31 1995-10-31 Composizione farmaceutica per il trattamento delle malattie autoimmuni

Publications (3)

Publication Number Publication Date
ITMI952242A0 ITMI952242A0 (it) 1995-10-31
ITMI952242A1 ITMI952242A1 (it) 1997-05-01
IT1276031B1 true IT1276031B1 (it) 1997-10-24

Family

ID=11372453

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95MI002242A IT1276031B1 (it) 1995-10-31 1995-10-31 Composizione farmaceutica per il trattamento delle malattie autoimmuni

Country Status (26)

Country Link
US (1) US6020356A (it)
EP (1) EP0858337B1 (it)
JP (1) JP4007615B2 (it)
KR (1) KR19990067237A (it)
CN (1) CN1229113C (it)
AT (1) ATE326965T1 (it)
AU (1) AU721841B2 (it)
BR (1) BR9611320B1 (it)
CA (1) CA2236256C (it)
CZ (1) CZ292258B6 (it)
DE (1) DE69636167T2 (it)
DK (1) DK0858337T3 (it)
EA (1) EA000826B1 (it)
ES (1) ES2264144T3 (it)
HU (1) HU228051B1 (it)
IL (1) IL124291A (it)
IT (1) IT1276031B1 (it)
MX (1) MX9803478A (it)
NO (1) NO324130B1 (it)
NZ (1) NZ321580A (it)
PL (1) PL186377B1 (it)
PT (1) PT858337E (it)
SK (1) SK284069B6 (it)
TR (1) TR199800765T2 (it)
WO (1) WO1997016185A2 (it)
ZA (1) ZA969060B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323201B1 (en) 1994-12-29 2001-11-27 The Regents Of The University Of California Compounds for inhibition of ceramide-mediated signal transduction
IT1293795B1 (it) 1997-07-28 1999-03-10 Angelini Ricerche Spa Farmaco attivo nel ridurre la produzione di proteina mcp-1
EP1615626B1 (en) * 2003-04-24 2009-10-14 Jagotec Ag Tablet with coloured core
PT2049123E (pt) 2006-08-03 2013-03-06 Horizon Pharma Ag Tratamento de doença reumatóide com glucocorticóide de libertação retardada
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
EP2391369A1 (en) * 2009-01-26 2011-12-07 Nitec Pharma AG Delayed-release glucocorticoid treatment of asthma
GEP20135878B (en) 2009-08-03 2013-07-10 Aziende Chimiche Riunite Angelini Francesco A C R A F S P A It Method of 1-benzyl-3-hydroxymethyl-1h-indazole preparation, derivatives thereof, and required magnesium intermediates
UA108742C2 (uk) 2009-09-23 2015-06-10 Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1
WO2013163758A1 (en) * 2012-05-01 2013-11-07 Boyd Shelley Romayne Methods for treating and diagnosing blinding eye diseases
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
WO2020261158A1 (en) 2019-06-25 2020-12-30 Translatum Medicus Inc. Processes of making 2-((1-benzyl-1h-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015816A1 (en) * 1989-06-16 1990-12-27 The Upjohn Company Suramin type compounds and angiostatic steroids to inhibit angiogenesis
IT1253703B (it) * 1991-04-22 1995-08-23 Angelini Francesco Ist Ricerca Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie
US5770589A (en) * 1993-07-27 1998-06-23 The University Of Sydney Treatment of macular degeneration
WO1995004533A2 (en) * 1993-08-04 1995-02-16 Andrulis Pharmaceuticals Corporation Treatment of rheumatoid arthritis with thalidomide alone or in combination with other anti-inflammatory agents
US5434170A (en) * 1993-12-23 1995-07-18 Andrulis Pharmaceuticals Corp. Method for treating neurocognitive disorders
MX9708620A (es) * 1995-05-10 1998-02-28 Pfizer Combinacion de metotrexate y tenidap para el tratamiento de artritis reumatoide.

Also Published As

Publication number Publication date
WO1997016185A2 (en) 1997-05-09
BR9611320B1 (pt) 2010-08-10
ITMI952242A1 (it) 1997-05-01
DK0858337T3 (da) 2006-09-18
ZA969060B (en) 1997-05-29
SK57998A3 (en) 1998-12-02
NO981951L (no) 1998-06-29
SK284069B6 (sk) 2004-09-08
PT858337E (pt) 2006-09-29
CA2236256A1 (en) 1997-05-09
JP4007615B2 (ja) 2007-11-14
NO324130B1 (no) 2007-09-03
EP0858337B1 (en) 2006-05-24
ES2264144T3 (es) 2006-12-16
MX9803478A (es) 1998-11-30
TR199800765T2 (xx) 1998-08-21
JPH11515020A (ja) 1999-12-21
HUP9901303A3 (en) 2001-04-28
DE69636167D1 (de) 2006-06-29
HU228051B1 (en) 2012-09-28
CZ292258B6 (cs) 2003-08-13
CN1229113C (zh) 2005-11-30
US6020356A (en) 2000-02-01
EA000826B1 (ru) 2000-04-24
CN1207042A (zh) 1999-02-03
KR19990067237A (ko) 1999-08-16
PL326371A1 (en) 1998-09-14
CZ132698A3 (cs) 1998-10-14
EP0858337A2 (en) 1998-08-19
HUP9901303A2 (hu) 1999-09-28
NO981951D0 (no) 1998-04-29
EA199800417A1 (ru) 1998-10-29
HK1018219A1 (en) 1999-12-17
WO1997016185A3 (en) 1997-07-03
BR9611320A (pt) 1999-03-02
ITMI952242A0 (it) 1995-10-31
AU7493896A (en) 1997-05-22
ATE326965T1 (de) 2006-06-15
DE69636167T2 (de) 2007-03-29
NZ321580A (en) 2000-02-28
IL124291A (en) 2001-06-14
CA2236256C (en) 2005-02-22
AU721841B2 (en) 2000-07-13
PL186377B1 (pl) 2003-12-31

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Legal Events

Date Code Title Description
0001 Granted