[go: up one dir, main page]

IT1168205B - Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione - Google Patents

Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione

Info

Publication number
IT1168205B
IT1168205B IT48724/83A IT4872483A IT1168205B IT 1168205 B IT1168205 B IT 1168205B IT 48724/83 A IT48724/83 A IT 48724/83A IT 4872483 A IT4872483 A IT 4872483A IT 1168205 B IT1168205 B IT 1168205B
Authority
IT
Italy
Prior art keywords
ganglioside
sub
monsial
derivate
fungal
Prior art date
Application number
IT48724/83A
Other languages
English (en)
Other versions
IT8348724A1 (it
IT8348724A0 (it
Inventor
Ezio Tubaro
Giovanni Cavallo
Original Assignee
Wellcome Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Italia filed Critical Wellcome Italia
Publication of IT8348724A0 publication Critical patent/IT8348724A0/it
Priority to IT48724/83A priority Critical patent/IT1168205B/it
Priority to US06/632,200 priority patent/US4728641A/en
Priority to AT84108621T priority patent/ATE75480T1/de
Priority to JP59151160A priority patent/JPS6084296A/ja
Priority to ES534494A priority patent/ES534494A0/es
Priority to HU842819A priority patent/HU198091B/hu
Priority to EP84108621A priority patent/EP0136438B1/en
Priority to DK356984A priority patent/DK166828B1/da
Priority to DE8484108621T priority patent/DE3485680D1/de
Publication of IT8348724A1 publication Critical patent/IT8348724A1/it
Application granted granted Critical
Publication of IT1168205B publication Critical patent/IT1168205B/it
Priority to US07/123,763 priority patent/US4831021A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT48724/83A 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione IT1168205B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT48724/83A IT1168205B (it) 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione
US06/632,200 US4728641A (en) 1983-07-21 1984-07-18 Ganglioside derivatives
ES534494A ES534494A0 (es) 1983-07-21 1984-07-20 Un procedimiento para preparar un derivado de mono-sialo-gangliosido
JP59151160A JPS6084296A (ja) 1983-07-21 1984-07-20 ガングリオシド誘導体
AT84108621T ATE75480T1 (de) 1983-07-21 1984-07-20 Gangliosid-derivate.
HU842819A HU198091B (en) 1983-07-21 1984-07-20 Process for producing ganglioside derivatives and pharmaceutical compositions comprising same as active ingedient
EP84108621A EP0136438B1 (en) 1983-07-21 1984-07-20 Ganglioside derivatives
DK356984A DK166828B1 (da) 1983-07-21 1984-07-20 Mono-sialo gangliosid gm1p, praeparater indeholdende dette samt anvendelse deraf til fremstilling af et laegemiddel
DE8484108621T DE3485680D1 (de) 1983-07-21 1984-07-20 Gangliosid-derivate.
US07/123,763 US4831021A (en) 1983-07-21 1987-11-23 Ganglioside derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48724/83A IT1168205B (it) 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione

Publications (3)

Publication Number Publication Date
IT8348724A0 IT8348724A0 (it) 1983-07-21
IT8348724A1 IT8348724A1 (it) 1985-01-21
IT1168205B true IT1168205B (it) 1987-05-20

Family

ID=11268264

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48724/83A IT1168205B (it) 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione

Country Status (9)

Country Link
US (2) US4728641A (it)
EP (1) EP0136438B1 (it)
JP (1) JPS6084296A (it)
AT (1) ATE75480T1 (it)
DE (1) DE3485680D1 (it)
DK (1) DK166828B1 (it)
ES (1) ES534494A0 (it)
HU (1) HU198091B (it)
IT (1) IT1168205B (it)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH660557A5 (fr) * 1984-10-26 1987-05-15 Nestle Sa Composition anti-bacterienne et procede de preparation de ses constituants actifs.
DK17885D0 (da) * 1985-01-14 1985-01-14 Karlsson Karl Anders Antiviralt middel
JPH0653764B2 (ja) * 1985-07-31 1994-07-20 三井東圧化学株式会社 モノシアロガングリオシドの製造法
EP0249008B1 (de) * 1986-05-09 1993-09-15 Pulverer, Gerhard, Prof. Dr.Dr.h.c. Verwendung von spezifischen Monosacchariden zur Herstellung eines Arzneimittels zur Verhinderung von Metastasen maligner Tumore
IT1208751B (it) * 1986-06-30 1989-07-10 Fidia Farmaceutici Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali
EP0508493A1 (en) * 1986-08-06 1992-10-14 Mect Corporation Ganglioside related compounds and method of producing the same
IT1212041B (it) * 1987-11-02 1989-11-08 Fidia Farmaceutici Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
AU7153991A (en) * 1989-12-13 1991-07-18 Glycomed Incorporated Synthesis of rotavirus receptor saccharides
WO1991008747A1 (en) * 1989-12-13 1991-06-27 Glycomed Incorporated Synthetic receptor molecules recognizable by a rotavirus
WO1993002686A1 (en) * 1991-07-31 1993-02-18 The Regents Of The University Of California Gangliosides with immunosuppressive ceramide moieties
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
DE4204907A1 (de) * 1992-02-14 1993-08-19 Reutter Werner Neuartige glykokonjugate mit n-substituierten neuraminsaeuren als mittel zur stimulierung des immunsystems
TW261533B (it) * 1992-07-16 1995-11-01 Kirin Brewery
WO1994009020A1 (fr) * 1992-10-22 1994-04-28 Kirin Beer Kabushiki Kaisha Nouveau shingoglycolipide et son utilisation
DE69416306T2 (de) * 1993-04-15 1999-06-17 Kirin Beer K.K., Tokio/Tokyo Sphingoglycolipid und verwendung davon
DE19602108A1 (de) * 1996-01-22 1997-07-24 Beiersdorf Ag Gegen Bakterien, Parasiten, Protozoen, Mycota und Viren wirksame Substanzen
US5747476A (en) 1996-07-17 1998-05-05 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoal myeloencephalitis
DE19643585A1 (de) * 1996-10-22 1998-04-23 Beiersdorf Ag Antiadhäsive Sphingolipide
WO2002018401A2 (en) * 2000-09-01 2002-03-07 Neuronyx, Inc. Novel synthetic gangliosides
AU2001288671A1 (en) * 2000-09-01 2002-03-13 Neuronyx, Inc. Novel synthetic gangliosides
US9969980B2 (en) * 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
EP1367395A1 (de) * 2002-05-02 2003-12-03 B.R.A.H.M.S Aktiengesellschaft Diagnose von Neoplasmen mit Hilfe von anti-Gangliosid-Antikörpern
EP1358910A1 (de) * 2002-05-02 2003-11-05 B.R.A.H.M.S Aktiengesellschaft Verfahren und Mittel zur Prävention, Hemmung und Therapie von Krebserkrankungen
US9969977B2 (en) * 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
NZ567841A (en) 2003-03-06 2010-01-29 Seneb Biosciences Inc Methods and compositions for the enzymatic synthesis of gangliosides
JP4965063B2 (ja) * 2004-05-07 2012-07-04 雪印メグミルク株式会社 口腔内細菌叢改善剤、抗菌剤及び生育促進剤。
CN100552315C (zh) 2004-09-23 2009-10-21 国家通风实验室有限公司 混合式通风机
US8354370B2 (en) * 2007-06-15 2013-01-15 Garnet Biotherapeutics, Inc. Administering a biological composition or compositions isolated from self-renewing colony forming somatic cell growth medium to treat diseases and disorders
US20090239834A1 (en) * 2008-03-21 2009-09-24 Braincells, Inc. Mcc-257 modulation of neurogenesis
DE102010024041A1 (de) * 2010-05-16 2013-04-04 Alfred Kroll Symtomfreiheit der Atemwege

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT295036B (de) * 1968-11-29 1971-12-27 Leikola Erkki E Verfahren zur Herstellung von neuen Produkten tierischen Ursprungs
US4125492A (en) * 1974-05-31 1978-11-14 Pedro Cuatrecasas Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers
FR2478104B1 (fr) * 1980-03-17 1986-08-08 Merieux Inst Nouveaux derives de gangliosides, leur preparation et leur application
AU542815B2 (en) * 1980-05-09 1985-03-14 Leffler, Hakon Carbohydrate derivatives for inhibiting bacterial adherence
CH658458A5 (fr) * 1981-12-17 1986-11-14 Lucchini Lab Sa Procede pour l'obtention du lacto-n-norhexaosyl ceramide.

Also Published As

Publication number Publication date
US4831021A (en) 1989-05-16
DE3485680D1 (de) 1992-06-04
EP0136438A2 (en) 1985-04-10
EP0136438A3 (en) 1987-05-13
US4728641A (en) 1988-03-01
ATE75480T1 (de) 1992-05-15
ES8603191A1 (es) 1985-12-01
DK356984D0 (da) 1984-07-20
DK166828B1 (da) 1993-07-19
ES534494A0 (es) 1985-12-01
HUT35690A (en) 1985-07-29
IT8348724A1 (it) 1985-01-21
JPS6084296A (ja) 1985-05-13
IT8348724A0 (it) 1983-07-21
HU198091B (en) 1989-07-28
EP0136438B1 (en) 1992-04-29
DK356984A (da) 1985-01-22

Similar Documents

Publication Publication Date Title
IT1168205B (it) Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione
AU549885B2 (en) Heparin degradation via ascorbic acid, cupric acetate and hydrogen peroxide
BR9906013A (pt) Derivados bicìclicos heteroaromáticos úteis como agentes anticancerìgenos
BG102708A (en) 4-aminopyrimidine derivatives, medicamentous preparations containing them, their application and method for their preparation
JPH08500589A (ja) アストラガルス ポリサッカライド免疫調節剤
EP0293826A3 (en) Therapeutic and prophylactic application of sulfated polysaccharides against aids
IE37913L (en) p-TOLUENESULPHONIC ACID SALT OF S-ADENOSYL-L-METHIONINE
JPS536412A (en) Preparation of n-containing polysaccharides
FR2387980A1 (fr) Nouveaux 2-(2,2-diarylalkyl)-1-azabicyclo (2.2.2) octanes, utiles notamment comme antidiarrheiques, et leur procede de preparation
SG26364G (en) 2', 3'-dideoxy-3'-fluorothymidine and related compounds for the treatment of adenovirus infections
Connors et al. The effect of glucose pretreatment on the carcinostatic and toxic activities of some alkylating agents
HK93990A (en) Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
IT8123603A0 (it) Sali stabili della s-adenosilmetionina, processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo.
ATE27914T1 (de) Verwendung von n-acetyl(alpha, beta) aspartylglutaminsaeure zur herstellung eines arzneimittels mit anti-allergischer wirkung zur lokalen verabreichung.
EP0539627B1 (en) A process for the purification of commercial carrageenins
FI59250C (fi) Foerfarande foer framstaellning av cancerostatiskt och immunstimulerande verkande 4-imino-1,3-diazabicyklo-(3,1,0)-hexan-2-on
Stähelin Delayed toxicity of epipodophyllotoxin derivatives (VM 26 and VP 16-213), due to a local effect
Watanabe Sinanomycin (Netropsin) Produced By Streptomyces Sp. No. 7618 Studies on the Antibiotic Substances From Actinomyces, XXXVII
DE2803681C2 (it)
FR2421175A1 (fr) Nouveaux sels d'ammonium quaternaire 1-(5-phenyl-2-furfurylidene-amino)-2,4-imidazolidinedione utiles notamment comme relaxants musculaires et leur procede de preparation
Veselý et al. Radioprotective effect of 5-azacytidine in AKR mice
CN1215849C (zh) 一种黄芩苷液配制方法
DiPalma et al. Importance of the methoxy group in antifibrillatory compounds
JPS575701A (en) Cationized dextran derivative, its production and use
ES8506749A1 (es) Procedimiento para la produccion de 1-n -(l-3-amino-2-hidroxipropionilo)- o 1-n-(l-4-amino-2-hidroxibutirilo)-2',3'-dideoxikanamicina a

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19930520