IS8125A - Kínasólínafleiður til að meðhöndla krabbamein - Google Patents
Kínasólínafleiður til að meðhöndla krabbameinInfo
- Publication number
- IS8125A IS8125A IS8125A IS8125A IS8125A IS 8125 A IS8125 A IS 8125A IS 8125 A IS8125 A IS 8125A IS 8125 A IS8125 A IS 8125A IS 8125 A IS8125 A IS 8125A
- Authority
- IS
- Iceland
- Prior art keywords
- cancer
- treatment
- quinazoline derivatives
- quinazoline
- derivatives
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03290951 | 2003-04-16 | ||
| PCT/GB2004/001614 WO2004094410A1 (en) | 2003-04-16 | 2004-04-14 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS8125A true IS8125A (is) | 2005-11-11 |
Family
ID=33305809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS8125A IS8125A (is) | 2003-04-16 | 2005-11-11 | Kínasólínafleiður til að meðhöndla krabbamein |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7691867B2 (is) |
| EP (1) | EP1613619B1 (is) |
| JP (1) | JP4709139B2 (is) |
| KR (1) | KR20060003351A (is) |
| CN (1) | CN1809557B (is) |
| AR (1) | AR043875A1 (is) |
| AT (1) | ATE390422T1 (is) |
| AU (1) | AU2004232527A1 (is) |
| BR (1) | BRPI0409427A (is) |
| CA (1) | CA2522079A1 (is) |
| CL (1) | CL2004000797A1 (is) |
| CO (1) | CO5640037A2 (is) |
| DE (1) | DE602004012725T2 (is) |
| ES (1) | ES2301981T3 (is) |
| IS (1) | IS8125A (is) |
| MX (1) | MXPA05011076A (is) |
| NO (1) | NO20054842L (is) |
| RU (1) | RU2005135337A (is) |
| TW (1) | TW200510392A (is) |
| UY (1) | UY28271A1 (is) |
| WO (1) | WO2004094410A1 (is) |
| ZA (1) | ZA200508372B (is) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04006260A (es) * | 2001-12-24 | 2005-03-31 | Astrazeneca Ab | Derivados de quinazolina sustituidos como inhibidores de cinasas aurora. |
| EP1578755B1 (en) * | 2002-12-24 | 2007-08-22 | AstraZeneca AB | Phosphonooxy quinazoline derivatives and their pharmaceutical use |
| ES2308182T3 (es) * | 2003-06-02 | 2008-12-01 | Astrazeneca Ab | Derivadosde (3-((quinazolin-4-il)amino)-1h-pirazol-1-il)acetamida y compuestos relacionados como inhibidores de quinasas aurora para el tratamiento de enfermedades proliferativas tales como el cancer. |
| US7572914B2 (en) | 2003-12-19 | 2009-08-11 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| SI1746999T1 (sl) | 2004-05-06 | 2012-01-31 | Warner Lambert Co | 4-fenilamino-kinazolin-6-il-amidi |
| US7550598B2 (en) | 2004-08-18 | 2009-06-23 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| JP2008515960A (ja) * | 2004-10-12 | 2008-05-15 | アストラゼネカ アクチボラグ | キノリン誘導体 |
| CA2581516C (en) | 2004-10-12 | 2013-06-11 | Astrazeneca Ab | Quinazoline derivatives |
| JP2008515961A (ja) * | 2004-10-12 | 2008-05-15 | アストラゼネカ アクチボラグ | 癌に対する使用のためのキナゾリン誘導体 |
| EP1812439B2 (en) | 2004-10-15 | 2017-12-06 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| PL1819698T3 (pl) | 2004-11-17 | 2011-08-31 | Rexahn Pharmaceuticals Inc | Pochodne 1-[(6-podstawione alkoksychinoksalinylo)aminokarbonylo]-4-(hetero)arylopiperazyny |
| EP1888572A1 (en) * | 2005-05-28 | 2008-02-20 | AstraZeneca AB | Quinazolines and their use as aurora kinase inhibitors |
| GB0510963D0 (en) * | 2005-05-28 | 2005-07-06 | Astrazeneca Ab | Chemical compounds |
| WO2007034183A2 (en) * | 2005-09-22 | 2007-03-29 | Astrazeneca Ab | Process for the preparation of 4-aminopyrazole derivatives |
| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| GB0601215D0 (en) * | 2006-01-21 | 2006-03-01 | Astrazeneca Ab | Chemical compounds |
| UY30183A1 (es) | 2006-03-02 | 2007-10-31 | Astrazeneca Ab | Derivados de quinolina |
| EP1994023A1 (en) * | 2006-03-02 | 2008-11-26 | AstraZeneca AB | Quinazoline derivatives |
| WO2007113565A1 (en) * | 2006-04-06 | 2007-10-11 | Astrazeneca Ab | Naphthyridine derivatives as anti-cancer agents |
| GB0609617D0 (en) | 2006-05-16 | 2006-06-21 | Astrazeneca Ab | Process & intermediate |
| BRPI0719883A2 (pt) | 2006-10-09 | 2015-05-05 | Takeda Pharmaceutical | Inibidores de quinase |
| FR2908409B1 (fr) * | 2006-11-10 | 2009-01-09 | Sanofi Aventis Sa | Pyrazoles substituees,compositions les contenant,procede de fabrication et utilisation |
| TWI577671B (zh) * | 2011-11-14 | 2017-04-11 | Sunshine Lake Pharma Co Ltd | Aminoquinazoline derivatives and salts thereof and methods of use thereof |
| CN103012428A (zh) | 2013-01-08 | 2013-04-03 | 中国药科大学 | 4-(五元杂环并嘧啶/吡啶取代)氨基-1H-3-吡唑甲酰胺类CDK/Aurora双重抑制剂及其用途 |
| CN104098551B (zh) * | 2013-04-03 | 2019-03-22 | 广东东阳光药业有限公司 | 作为欧若拉激酶抑制剂的取代喹唑啉类衍生物 |
| CN103382158B (zh) * | 2013-07-29 | 2015-11-18 | 张家港市大伟助剂有限公司 | 一种2-环戊基氨基乙醇的制备方法 |
| WO2015040169A1 (en) * | 2013-09-19 | 2015-03-26 | Pierre Fabre Medicament | Quinazoline derivatives and their use as dna methyltransferase inhibitors |
| WO2025162459A1 (zh) * | 2024-02-02 | 2025-08-07 | 北京大学 | 新配体靶向化合物、螯合物、组合物及其用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5710158A (en) * | 1991-05-10 | 1998-01-20 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| TW321649B (is) * | 1994-11-12 | 1997-12-01 | Zeneca Ltd | |
| DE69622183D1 (de) * | 1995-11-07 | 2002-08-08 | Kirin Brewery | Chinolinderivate und chinazolinderivate welche die autophosphorylierung des von blutplättchen abstammenden wachstumsfaktorrezeptors inhibiren und sie enthaltende pharmazeutische zusammensetzungen |
| GB9922171D0 (en) * | 1999-09-21 | 1999-11-17 | Zeneca Ltd | Chemical compounds |
| PL354323A1 (en) * | 1999-09-21 | 2004-01-12 | Astrazeneca Ab | Quinazoline derivatives and their use as pharmaceuticals |
| ES2305081T3 (es) | 2000-06-28 | 2008-11-01 | Astrazeneca Ab | Derivados de quinozolina sustituidos y su uso como inhibidores. |
| MXPA04006260A (es) * | 2001-12-24 | 2005-03-31 | Astrazeneca Ab | Derivados de quinazolina sustituidos como inhibidores de cinasas aurora. |
| CN1688549A (zh) * | 2002-08-23 | 2005-10-26 | 麒麟麦酒株式会社 | 具有TGFβ抑制活性的化合物和含所述化合物的药用组合物 |
| WO2004058752A1 (en) | 2002-12-24 | 2004-07-15 | Astrazeneca Ab | Quinazoline compounds |
| EP1575966B1 (en) | 2002-12-24 | 2008-10-29 | AstraZeneca AB | Therapeutic quinazoline derivatives |
| EP1578755B1 (en) * | 2002-12-24 | 2007-08-22 | AstraZeneca AB | Phosphonooxy quinazoline derivatives and their pharmaceutical use |
| ES2308182T3 (es) * | 2003-06-02 | 2008-12-01 | Astrazeneca Ab | Derivadosde (3-((quinazolin-4-il)amino)-1h-pirazol-1-il)acetamida y compuestos relacionados como inhibidores de quinasas aurora para el tratamiento de enfermedades proliferativas tales como el cancer. |
| TW200505452A (en) * | 2003-06-17 | 2005-02-16 | Astrazeneca Ab | Chemical compounds |
-
2004
- 2004-04-14 BR BRPI0409427-1A patent/BRPI0409427A/pt not_active IP Right Cessation
- 2004-04-14 DE DE602004012725T patent/DE602004012725T2/de not_active Expired - Lifetime
- 2004-04-14 AU AU2004232527A patent/AU2004232527A1/en not_active Abandoned
- 2004-04-14 CA CA002522079A patent/CA2522079A1/en not_active Abandoned
- 2004-04-14 WO PCT/GB2004/001614 patent/WO2004094410A1/en not_active Ceased
- 2004-04-14 CN CN2004800165460A patent/CN1809557B/zh not_active Expired - Fee Related
- 2004-04-14 KR KR1020057019633A patent/KR20060003351A/ko not_active Withdrawn
- 2004-04-14 JP JP2006506123A patent/JP4709139B2/ja not_active Expired - Fee Related
- 2004-04-14 AT AT04727325T patent/ATE390422T1/de not_active IP Right Cessation
- 2004-04-14 EP EP04727325A patent/EP1613619B1/en not_active Expired - Lifetime
- 2004-04-14 CL CL200400797A patent/CL2004000797A1/es unknown
- 2004-04-14 MX MXPA05011076A patent/MXPA05011076A/es unknown
- 2004-04-14 ES ES04727325T patent/ES2301981T3/es not_active Expired - Lifetime
- 2004-04-14 US US10/552,425 patent/US7691867B2/en not_active Expired - Fee Related
- 2004-04-14 RU RU2005135337/04A patent/RU2005135337A/ru not_active Application Discontinuation
- 2004-04-16 TW TW093110602A patent/TW200510392A/zh unknown
- 2004-04-16 UY UY28271A patent/UY28271A1/es not_active Application Discontinuation
- 2004-04-16 AR ARP040101300A patent/AR043875A1/es not_active Application Discontinuation
-
2005
- 2005-10-14 ZA ZA200508372A patent/ZA200508372B/en unknown
- 2005-10-19 NO NO20054842A patent/NO20054842L/no not_active Application Discontinuation
- 2005-11-11 IS IS8125A patent/IS8125A/is unknown
- 2005-11-15 CO CO05115649A patent/CO5640037A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1809557A (zh) | 2006-07-26 |
| ZA200508372B (en) | 2007-04-25 |
| RU2005135337A (ru) | 2006-06-10 |
| ATE390422T1 (de) | 2008-04-15 |
| CO5640037A2 (es) | 2006-05-31 |
| EP1613619A1 (en) | 2006-01-11 |
| EP1613619B1 (en) | 2008-03-26 |
| DE602004012725T2 (de) | 2009-04-16 |
| MXPA05011076A (es) | 2006-01-24 |
| AU2004232527A1 (en) | 2004-11-04 |
| US7691867B2 (en) | 2010-04-06 |
| UY28271A1 (es) | 2004-11-30 |
| TW200510392A (en) | 2005-03-16 |
| ES2301981T3 (es) | 2008-07-01 |
| CN1809557B (zh) | 2012-07-04 |
| JP4709139B2 (ja) | 2011-06-22 |
| KR20060003351A (ko) | 2006-01-10 |
| HK1086573A1 (en) | 2006-09-22 |
| DE602004012725D1 (de) | 2008-05-08 |
| US20060270692A1 (en) | 2006-11-30 |
| AR043875A1 (es) | 2005-08-17 |
| JP2006523660A (ja) | 2006-10-19 |
| CA2522079A1 (en) | 2004-11-04 |
| CL2004000797A1 (es) | 2005-05-27 |
| NO20054842L (no) | 2005-11-08 |
| BRPI0409427A (pt) | 2006-04-18 |
| WO2004094410A1 (en) | 2004-11-04 |
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