IS7560A - Annars stigs amínó anilínísk piperidín sem MCH1 mótlyf og notkun á þeim - Google Patents
Annars stigs amínó anilínísk piperidín sem MCH1 mótlyf og notkun á þeimInfo
- Publication number
- IS7560A IS7560A IS7560A IS7560A IS7560A IS 7560 A IS7560 A IS 7560A IS 7560 A IS7560 A IS 7560A IS 7560 A IS7560 A IS 7560A IS 7560 A IS7560 A IS 7560A
- Authority
- IS
- Iceland
- Prior art keywords
- secondary amino
- amino aniline
- mch1 antagonist
- aniline piperidine
- piperidine
- Prior art date
Links
- 101150104680 MCH1 gene Proteins 0.000 title 1
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N N-phenyl amine Natural products NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 title 1
- 101100382379 Rattus norvegicus Cap1 gene Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 title 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18914502A | 2002-07-03 | 2002-07-03 | |
| PCT/US2003/021391 WO2004005257A1 (en) | 2002-07-03 | 2003-07-03 | Secondary amino anilinic piperidines as mch1 antagonists and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS7560A true IS7560A (is) | 2004-11-26 |
Family
ID=30114020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7560A IS7560A (is) | 2002-07-03 | 2004-11-26 | Annars stigs amínó anilínísk piperidín sem MCH1 mótlyf og notkun á þeim |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7473698B2 (is) |
| EP (1) | EP1556351A4 (is) |
| JP (1) | JP2005532399A (is) |
| KR (1) | KR20050034710A (is) |
| CN (1) | CN1319945C (is) |
| AU (1) | AU2003259098A1 (is) |
| BR (1) | BR0312257A (is) |
| CA (1) | CA2485379A1 (is) |
| EA (1) | EA008826B1 (is) |
| IL (1) | IL165730A0 (is) |
| IS (1) | IS7560A (is) |
| MX (1) | MXPA04012103A (is) |
| NO (1) | NO20050113L (is) |
| NZ (1) | NZ536329A (is) |
| PL (1) | PL373621A1 (is) |
| UA (1) | UA77536C2 (is) |
| WO (1) | WO2004005257A1 (is) |
| ZA (1) | ZA200409425B (is) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105544B2 (en) | 2001-07-05 | 2006-09-12 | Synaptic Pharmaceutical Corporation | Substituted alkyl amido piperidines |
| US7199135B2 (en) | 2001-07-05 | 2007-04-03 | H. Lundbeck A/S | Substituted alkyl amido piperidines |
| US20050154020A1 (en) * | 2004-01-14 | 2005-07-14 | Synaptic Pharmaceutical Corporation | 4-Aryl piperidines |
| US20050154022A1 (en) * | 2004-01-14 | 2005-07-14 | H. Lundbeck A/S | 4-aryl piperidines |
| WO2006015279A1 (en) * | 2004-07-28 | 2006-02-09 | Neurogen Corporation | Heterocyclic diamine compounds as ligands of the melanin concentrating hormone receptor useful for the treatment of obesity, diabetes, eating and sexual disorders |
| US7329656B2 (en) | 2004-10-08 | 2008-02-12 | H. Lundbeck A/S | Arylthiobenzylpiperidine derivatives |
| US7446204B2 (en) | 2004-10-08 | 2008-11-04 | H. Lundbeck A/S | Amino substituted aryloxybenzylpiperidine derivatives |
| US20060079683A1 (en) * | 2004-10-08 | 2006-04-13 | Marzabadi Mohammad R | Arylthiobenzylpiperidine derivatives |
| US9452980B2 (en) | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
| RS60825B1 (sr) | 2016-03-17 | 2020-10-30 | Hoffmann La Roche | Aktivnost derivata 5-etiol-4-metil-pirazol-3-karboksamida kao agonista taar-a |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2058061T3 (es) * | 1985-10-25 | 1994-11-01 | Beecham Group Plc | Derivado de piperidina, su preparacion y su uso como medicamento. |
| FR2744448B1 (fr) | 1996-02-02 | 1998-04-24 | Pf Medicament | Nouvelles piperidines derivees d'aryl piperazine, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| ES2157148B1 (es) * | 1998-11-18 | 2002-03-01 | Faes Fabrica Espanola De Produ | Nuevas piperidinas 4-sustituidas. |
| US6326381B1 (en) * | 1998-12-17 | 2001-12-04 | American Home Products Corporation | Arylpiperidine and aryl-1,2,5,6-tetrahydropyidine amide derivates |
| US20030082623A1 (en) * | 1998-12-31 | 2003-05-01 | Beth Borowsky | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof |
| WO2002006245A1 (en) * | 2000-07-05 | 2002-01-24 | Synaptic Pharmarceutical Corporation | Selective melanin concentrating hormone-1 (mch1) receptor antagonists and uses thereof |
| JP2004502423A (ja) * | 2000-07-05 | 2004-01-29 | シナプティック・ファーマスーティカル・コーポレーション | ヒトメラニン濃縮ホルモン受容体（ｍｃｈ１）をコードするｄｎａ及びその使用 |
| EP1389189A2 (en) | 2001-05-22 | 2004-02-18 | Neurogen Corporation | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues |
| EA005934B1 (ru) | 2001-07-05 | 2005-08-25 | Х. Лундбекк А/С | Замещённые анилиновые пиперидины в качестве селективных антагонистов мсн |
-
2003
- 2003-03-07 UA UA20041210489A patent/UA77536C2/uk unknown
- 2003-07-03 US US10/518,675 patent/US7473698B2/en not_active Expired - Fee Related
- 2003-07-03 BR BR0312257-3A patent/BR0312257A/pt not_active IP Right Cessation
- 2003-07-03 KR KR1020057000078A patent/KR20050034710A/ko not_active Ceased
- 2003-07-03 CN CNB038157667A patent/CN1319945C/zh not_active Expired - Fee Related
- 2003-07-03 WO PCT/US2003/021391 patent/WO2004005257A1/en not_active Ceased
- 2003-07-03 IL IL16573003A patent/IL165730A0/xx unknown
- 2003-07-03 MX MXPA04012103A patent/MXPA04012103A/es active IP Right Grant
- 2003-07-03 EA EA200500152A patent/EA008826B1/ru not_active IP Right Cessation
- 2003-07-03 NZ NZ536329A patent/NZ536329A/en unknown
- 2003-07-03 AU AU2003259098A patent/AU2003259098A1/en not_active Abandoned
- 2003-07-03 EP EP03763374A patent/EP1556351A4/en not_active Withdrawn
- 2003-07-03 CA CA002485379A patent/CA2485379A1/en not_active Abandoned
- 2003-07-03 JP JP2004520047A patent/JP2005532399A/ja not_active Withdrawn
- 2003-07-03 PL PL03373621A patent/PL373621A1/xx not_active Application Discontinuation
-
2004
- 2004-11-23 ZA ZA200409425A patent/ZA200409425B/en unknown
- 2004-11-26 IS IS7560A patent/IS7560A/is unknown
-
2005
- 2005-01-10 NO NO20050113A patent/NO20050113L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1319945C (zh) | 2007-06-06 |
| CA2485379A1 (en) | 2004-01-15 |
| BR0312257A (pt) | 2005-04-12 |
| HK1080471A1 (en) | 2006-04-28 |
| MXPA04012103A (es) | 2005-04-19 |
| PL373621A1 (en) | 2005-09-05 |
| EP1556351A1 (en) | 2005-07-27 |
| IL165730A0 (en) | 2006-01-15 |
| WO2004005257A1 (en) | 2004-01-15 |
| UA77536C2 (en) | 2006-12-15 |
| US7473698B2 (en) | 2009-01-06 |
| CN1665786A (zh) | 2005-09-07 |
| EP1556351A4 (en) | 2007-07-25 |
| NZ536329A (en) | 2007-06-29 |
| NO20050113L (no) | 2005-01-10 |
| US20050245743A1 (en) | 2005-11-03 |
| EA200500152A1 (ru) | 2005-06-30 |
| ZA200409425B (en) | 2006-04-26 |
| JP2005532399A (ja) | 2005-10-27 |
| KR20050034710A (ko) | 2005-04-14 |
| EA008826B1 (ru) | 2007-08-31 |
| AU2003259098A1 (en) | 2004-01-23 |
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