IS7069A - Aðferð til að framleiða zaleplon - Google Patents
Aðferð til að framleiða zaleplonInfo
- Publication number
- IS7069A IS7069A IS7069A IS7069A IS7069A IS 7069 A IS7069 A IS 7069A IS 7069 A IS7069 A IS 7069A IS 7069 A IS7069 A IS 7069A IS 7069 A IS7069 A IS 7069A
- Authority
- IS
- Iceland
- Prior art keywords
- zaleplon
- producing
- producing zaleplon
- Prior art date
Links
- HUNXMJYCHXQEGX-UHFFFAOYSA-N zaleplon Chemical compound CCN(C(C)=O)C1=CC=CC(C=2N3N=CC(=C3N=CC=2)C#N)=C1 HUNXMJYCHXQEGX-UHFFFAOYSA-N 0.000 title 1
- 229960004010 zaleplon Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29763501P | 2001-06-12 | 2001-06-12 | |
| PCT/US2002/018567 WO2002100828A2 (en) | 2001-06-12 | 2002-06-12 | Process for the production of zaleplon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS7069A true IS7069A (is) | 2003-12-10 |
Family
ID=23147125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7069A IS7069A (is) | 2001-06-12 | 2003-12-10 | Aðferð til að framleiða zaleplon |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6884888B2 (is) |
| EP (1) | EP1406871A4 (is) |
| JP (1) | JP2005507858A (is) |
| KR (1) | KR20040007683A (is) |
| CN (1) | CN1537113A (is) |
| CA (1) | CA2450384A1 (is) |
| CZ (1) | CZ20033544A3 (is) |
| DE (1) | DE02778962T1 (is) |
| ES (1) | ES2223311T1 (is) |
| HR (1) | HRP20040016A2 (is) |
| HU (1) | HUP0402257A2 (is) |
| IL (1) | IL159281A0 (is) |
| IS (1) | IS7069A (is) |
| MX (1) | MXPA03011485A (is) |
| NO (1) | NO20035538D0 (is) |
| PL (1) | PL372942A1 (is) |
| SK (1) | SK16232003A3 (is) |
| TR (1) | TR200402588T3 (is) |
| WO (1) | WO2002100828A2 (is) |
| ZA (1) | ZA200309677B (is) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1406871A4 (en) * | 2001-06-12 | 2005-01-26 | Biogal Gyogyszergyar | PROCESS FOR THE PRODUCTION OF N- 3- (3-CYANOPYRAZOLO 1,5-A] PYRIMIDINE-7-YLE) PHENYL] -N-ETHYLACETAMIDE (ZALEPLON) |
| US20050032818A1 (en) * | 2001-06-12 | 2005-02-10 | Entire Interest | N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-5-yl)phenyl]-N-ethylacetamide and crystalline forms of zaleplon |
| WO2003011228A2 (en) * | 2001-08-01 | 2003-02-13 | Biogal Gyogyszergyar Rt | Purification and crystalline forms of zaleplon |
| WO2003068238A1 (en) * | 2002-02-15 | 2003-08-21 | Biogal Gyogyszergyar Rt. | Powder composition comprising zaleplon of defined particle size distribution and pharmaceutical products made therefrom |
| PL207322B1 (pl) * | 2002-05-14 | 2010-11-30 | Adamed Społka Z Ograniczoną Odpowiedzialnością | Sposób wytwarzania zaleplonu |
| AU2002343201A1 (en) * | 2002-10-16 | 2004-05-04 | Sanmar Speciality Chemicals Limited | Synthesis of zaleplon |
| CZ20023575A3 (cs) * | 2002-10-25 | 2004-01-14 | Léčiva, A.S. | Způsob výroby N-ethyl-N-[3-(3-methyl-pyrazolo[1,5-a]pyrimidin-7-yl)-fenyl]-acetamidu (zaleplonu) |
| US7772394B2 (en) | 2003-09-04 | 2010-08-10 | Cipla Limited | Zaleplon synthesis |
| DE602004025747D1 (de) * | 2004-01-14 | 2010-04-08 | Mallinckrodt Inc | Zweiphasiges verfahren zur synthese ausgewählter pyrazolopyrimidine |
| HUP0400325A3 (en) * | 2004-02-02 | 2005-11-28 | Richter Gedeon Vegyeszet | Pure n-[3-(-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-n-ethyl-acetamide, process for its preparation and intermediates |
| WO2005099712A2 (en) * | 2004-04-19 | 2005-10-27 | Sanmar Speciality Chemicals Limited | Process for preparation of n-[3-(3-cyanopyrazolo [1,5-a]pyrimidin-7-yl)phenyl]-n-ethylacetamide |
| WO2006070244A2 (en) * | 2004-11-22 | 2006-07-06 | Bakulesh Mafatlal Khamar | A process for the preparation of zaleplon |
| CN102816163A (zh) * | 2012-08-20 | 2012-12-12 | 四川禾邦阳光制药股份有限公司 | 扎来普隆的新晶型及制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4626538A (en) | 1983-06-23 | 1986-12-02 | American Cyanamid Company | [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines |
| US5714607A (en) * | 1995-12-01 | 1998-02-03 | American Cyanamid Company | Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide |
| US6485746B1 (en) * | 2000-08-25 | 2002-11-26 | Neurocrine Biosciences, Inc. | Controlled-release sedative-hypnotic compositions and methods related thereto |
| US6384221B1 (en) * | 1999-09-02 | 2002-05-07 | Neurocrine Biosciences, Inc. | Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto |
| CN1610682A (zh) * | 2000-08-03 | 2005-04-27 | Wyeth公司 | 扎来普隆多晶型物及其制备方法 |
| AR029780A1 (es) * | 2000-12-13 | 2003-07-16 | Gador Sa | Procedimiento mejorado para la obtencion de n-[3(3-ciano-pirazolo[1,5-a]pirimidin-7-il)fenil]-n-etil-acetamida |
| EP1406871A4 (en) * | 2001-06-12 | 2005-01-26 | Biogal Gyogyszergyar | PROCESS FOR THE PRODUCTION OF N- 3- (3-CYANOPYRAZOLO 1,5-A] PYRIMIDINE-7-YLE) PHENYL] -N-ETHYLACETAMIDE (ZALEPLON) |
| WO2003011228A2 (en) * | 2001-08-01 | 2003-02-13 | Biogal Gyogyszergyar Rt | Purification and crystalline forms of zaleplon |
| PL207322B1 (pl) * | 2002-05-14 | 2010-11-30 | Adamed Społka Z Ograniczoną Odpowiedzialnością | Sposób wytwarzania zaleplonu |
-
2002
- 2002-06-12 EP EP02778962A patent/EP1406871A4/en not_active Withdrawn
- 2002-06-12 PL PL02372942A patent/PL372942A1/xx not_active Application Discontinuation
- 2002-06-12 TR TR2004/02588T patent/TR200402588T3/xx unknown
- 2002-06-12 JP JP2003503597A patent/JP2005507858A/ja active Pending
- 2002-06-12 CA CA002450384A patent/CA2450384A1/en not_active Abandoned
- 2002-06-12 ES ES02778962T patent/ES2223311T1/es active Pending
- 2002-06-12 US US10/170,673 patent/US6884888B2/en not_active Expired - Fee Related
- 2002-06-12 CN CNA028150112A patent/CN1537113A/zh active Pending
- 2002-06-12 KR KR10-2003-7016185A patent/KR20040007683A/ko not_active Ceased
- 2002-06-12 HR HR20040016A patent/HRP20040016A2/hr not_active Application Discontinuation
- 2002-06-12 HU HU0402257A patent/HUP0402257A2/hu unknown
- 2002-06-12 SK SK1623-2003A patent/SK16232003A3/sk unknown
- 2002-06-12 DE DE02778962T patent/DE02778962T1/de active Pending
- 2002-06-12 IL IL15928102A patent/IL159281A0/xx unknown
- 2002-06-12 MX MXPA03011485A patent/MXPA03011485A/es not_active Application Discontinuation
- 2002-06-12 CZ CZ20033544A patent/CZ20033544A3/cs unknown
- 2002-06-12 WO PCT/US2002/018567 patent/WO2002100828A2/en not_active Ceased
-
2003
- 2003-12-10 IS IS7069A patent/IS7069A/is unknown
- 2003-12-11 NO NO20035538A patent/NO20035538D0/no not_active Application Discontinuation
- 2003-12-12 ZA ZA200309677A patent/ZA200309677B/en unknown
-
2005
- 2005-02-25 US US11/067,044 patent/US20050187225A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL159281A0 (en) | 2004-06-01 |
| US20030040522A1 (en) | 2003-02-27 |
| SK16232003A3 (sk) | 2004-12-01 |
| HRP20040016A2 (en) | 2004-10-31 |
| US6884888B2 (en) | 2005-04-26 |
| ES2223311T1 (es) | 2005-03-01 |
| TR200402588T3 (tr) | 2004-11-22 |
| HUP0402257A2 (hu) | 2005-02-28 |
| US20050187225A1 (en) | 2005-08-25 |
| WO2002100828A2 (en) | 2002-12-19 |
| ZA200309677B (en) | 2004-12-13 |
| EP1406871A2 (en) | 2004-04-14 |
| PL372942A1 (en) | 2005-08-08 |
| DE02778962T1 (de) | 2005-02-10 |
| WO2002100828A3 (en) | 2003-05-01 |
| EP1406871A4 (en) | 2005-01-26 |
| JP2005507858A (ja) | 2005-03-24 |
| CZ20033544A3 (cs) | 2004-11-10 |
| NO20035538D0 (no) | 2003-12-11 |
| KR20040007683A (ko) | 2004-01-24 |
| CA2450384A1 (en) | 2002-12-19 |
| CN1537113A (zh) | 2004-10-13 |
| MXPA03011485A (es) | 2004-06-11 |
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