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IS6524A - 5-alkýlpyrídó(3-3-D)pyrimídín týrósín kínasa tálmar - Google Patents

5-alkýlpyrídó(3-3-D)pyrimídín týrósín kínasa tálmar

Info

Publication number
IS6524A
IS6524A IS6524A IS6524A IS6524A IS 6524 A IS6524 A IS 6524A IS 6524 A IS6524 A IS 6524A IS 6524 A IS6524 A IS 6524A IS 6524 A IS6524 A IS 6524A
Authority
IS
Iceland
Prior art keywords
alkylpyrido
tyrosine kinase
kinase inhibitors
pyrimidine
pyrimidine tyrosine
Prior art date
Application number
IS6524A
Other languages
English (en)
Icelandic (is)
Inventor
John Booth Richard
Myra Dobrusin Ellen
Laurence Toogood Peter
Norman Vanderwel Scott
Original Assignee
Warner-Lambert Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company filed Critical Warner-Lambert Company
Publication of IS6524A publication Critical patent/IS6524A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IS6524A 2000-03-06 2002-08-23 5-alkýlpyrídó(3-3-D)pyrimídín týrósín kínasa tálmar IS6524A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18712400P 2000-03-06 2000-03-06
PCT/US2001/002657 WO2001070741A1 (en) 2000-03-06 2001-01-29 5-alkylpyrido[2,3-d]pyrimidines tyrosine kinase inhibitors

Publications (1)

Publication Number Publication Date
IS6524A true IS6524A (is) 2002-08-23

Family

ID=22687699

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6524A IS6524A (is) 2000-03-06 2002-08-23 5-alkýlpyrídó(3-3-D)pyrimídín týrósín kínasa tálmar

Country Status (36)

Country Link
EP (1) EP1268476A1 (xx)
JP (1) JP2003528101A (xx)
KR (1) KR20020075805A (xx)
CN (1) CN1422268A (xx)
AP (1) AP2002002643A0 (xx)
AR (1) AR034119A1 (xx)
AU (1) AU2001233028A1 (xx)
BG (1) BG107161A (xx)
BR (1) BR0109056A (xx)
CA (1) CA2401368A1 (xx)
CO (1) CO5280200A1 (xx)
CR (1) CR6736A (xx)
CZ (1) CZ20022929A3 (xx)
DZ (1) DZ3308A1 (xx)
EA (1) EA200200802A1 (xx)
EE (1) EE200200506A (xx)
GT (1) GT200100037A (xx)
HN (1) HN2001000040A (xx)
HR (1) HRP20020798A2 (xx)
HU (1) HUP0300136A2 (xx)
IL (1) IL151480A0 (xx)
IS (1) IS6524A (xx)
MA (1) MA26881A1 (xx)
MX (1) MXPA02008535A (xx)
NO (1) NO20024235L (xx)
NZ (1) NZ520962A (xx)
OA (1) OA12227A (xx)
PA (1) PA8513201A1 (xx)
PE (1) PE20011177A1 (xx)
PL (1) PL358271A1 (xx)
SK (1) SK12472002A3 (xx)
SV (1) SV2001000338A (xx)
TN (1) TNSN01036A1 (xx)
WO (1) WO2001070741A1 (xx)
YU (1) YU66502A (xx)
ZA (1) ZA200207110B (xx)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
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BR0114829A (pt) 2000-10-23 2003-09-23 Smithkline Beecham Corp Novos compostos
WO2002064594A2 (en) * 2001-02-12 2002-08-22 F. Hoffmann-La Roche Ag 6-substituted pyrido-pyrimidines
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US20030105115A1 (en) * 2001-06-21 2003-06-05 Metcalf Chester A. Novel pyridopyrimidines and uses thereof
EP1408985A4 (en) * 2001-06-21 2006-03-22 Ariad Pharma Inc NEW PYRIDOPYRIMIDONE AND ITS USES
PL220952B1 (pl) * 2002-01-22 2016-01-29 Warner Lambert Co 2-(Pirydyn-2-yloamino)pirydo[2,3-d]pirymidyn-7-ony
JP4603268B2 (ja) 2002-04-19 2010-12-22 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 新規化合物
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AU2003273675A1 (en) 2002-10-09 2004-05-04 Wayne R. Danter Protein tyrosine kinase inhibitors
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US6861422B2 (en) 2003-02-26 2005-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
ATE412650T1 (de) * 2003-07-11 2008-11-15 Warner Lambert Co Isethionat salz eines selektiven cdk4 inhibitors
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FR2873118B1 (fr) 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
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US7728134B2 (en) 2004-08-14 2010-06-01 Boehringer Ingelheim International Gmbh Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
EP1630163A1 (de) 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
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US7737155B2 (en) * 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
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ES2694787T3 (es) * 2013-02-21 2018-12-27 Pfizer Inc. Formas sólidas de un inhibidor selectivo de CDK4/6
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US10449195B2 (en) 2016-03-29 2019-10-22 Shenzhen Pharmacin Co., Ltd. Pharmaceutical formulation of palbociclib and a preparation method thereof
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MA45920B1 (fr) 2016-08-15 2021-08-31 Pfizer Inhibiteurs de pyridopyrimidinone cdk2/4/6
CN110809576B (zh) * 2017-03-03 2022-08-30 奥克兰联合服务有限公司 Fgfr激酶抑制剂和药物用途
WO2019161224A1 (en) 2018-02-15 2019-08-22 GiraFpharma LLC Heterocyclic compounds as kinase inhibitors
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CN112759589B (zh) * 2019-11-01 2022-04-08 暨南大学 嘧啶并吡啶酮类化合物及其应用
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WO2022258023A1 (zh) * 2021-06-09 2022-12-15 郑州同源康医药有限公司 用作cdk激酶抑制剂的化合物及其应用
US20250388576A1 (en) * 2022-09-16 2025-12-25 East China Normal University Pyridonopyrimidine derivative as rsk inhibitor and use thereof
WO2024099403A1 (zh) * 2022-11-10 2024-05-16 北京普祺医药科技股份有限公司 一种具有软药性质的硫醚类化合物、药物组合物及其用途
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Family Cites Families (3)

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US5620981A (en) * 1995-05-03 1997-04-15 Warner-Lambert Company Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
ES2301194T3 (es) * 1997-02-05 2008-06-16 Warner-Lambert Company Llc Pirido 2,3-d pirimidinas y 4-aminopirimidinas como inhibidores de la proliferacion celular.
EA003640B1 (ru) * 1998-05-26 2003-08-28 Варнер-Ламберт Компани Бициклические пиримидины и бициклические 3,4-дигидропиримидины как ингибиторы клеточной пролиферации

Also Published As

Publication number Publication date
YU66502A (sh) 2005-09-19
TNSN01036A1 (en) 2005-11-10
AR034119A1 (es) 2004-02-04
SK12472002A3 (sk) 2003-04-01
AU2001233028A1 (en) 2001-10-03
HUP0300136A2 (en) 2003-05-28
SV2001000338A (es) 2001-11-30
NO20024235D0 (no) 2002-09-05
IL151480A0 (en) 2003-04-10
CN1422268A (zh) 2003-06-04
PL358271A1 (en) 2004-08-09
BR0109056A (pt) 2003-06-03
EE200200506A (et) 2004-02-16
MA26881A1 (fr) 2004-12-20
OA12227A (en) 2004-03-18
HRP20020798A2 (en) 2004-02-29
EP1268476A1 (en) 2003-01-02
NZ520962A (en) 2003-09-26
CA2401368A1 (en) 2001-09-27
GT200100037A (es) 2002-03-04
ZA200207110B (en) 2003-12-04
NO20024235L (no) 2002-11-05
WO2001070741A1 (en) 2001-09-27
KR20020075805A (ko) 2002-10-05
PA8513201A1 (es) 2003-06-30
CR6736A (es) 2004-03-10
CZ20022929A3 (cs) 2003-02-12
JP2003528101A (ja) 2003-09-24
CO5280200A1 (es) 2003-05-30
PE20011177A1 (es) 2001-11-23
HN2001000040A (es) 2001-09-06
DZ3308A1 (fr) 2001-09-27
BG107161A (en) 2003-06-30
AP2002002643A0 (en) 2002-12-31
EA200200802A1 (ru) 2003-02-27
MXPA02008535A (es) 2002-12-13

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