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IS6161A - Fjölgervingar af kristölluðu (2-benshýdrýl-1-azabísýkló [2,2,2]okt-3-ýl)-(5-ísóprópýl-2-metoxýbensýl)-ammóníumklóríði sem NK-1 viðtaka mótlyf - Google Patents

Fjölgervingar af kristölluðu (2-benshýdrýl-1-azabísýkló [2,2,2]okt-3-ýl)-(5-ísóprópýl-2-metoxýbensýl)-ammóníumklóríði sem NK-1 viðtaka mótlyf

Info

Publication number
IS6161A
IS6161A IS6161A IS6161A IS6161A IS 6161 A IS6161 A IS 6161A IS 6161 A IS6161 A IS 6161A IS 6161 A IS6161 A IS 6161A IS 6161 A IS6161 A IS 6161A
Authority
IS
Iceland
Prior art keywords
benzhydryl
azabicyclo
methoxybenzyl
polymerisation
oct
Prior art date
Application number
IS6161A
Other languages
English (en)
Inventor
John Meldrum Allen Douglas
Anthony Appleton Troy
Jon Gumkowski Michael
Joseph Muehlbauer David
Norris Timothy
Original Assignee
Pfizer Product Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Product Inc. filed Critical Pfizer Product Inc.
Publication of IS6161A publication Critical patent/IS6161A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IS6161A 1999-06-22 2001-11-13 Fjölgervingar af kristölluðu (2-benshýdrýl-1-azabísýkló [2,2,2]okt-3-ýl)-(5-ísóprópýl-2-metoxýbensýl)-ammóníumklóríði sem NK-1 viðtaka mótlyf IS6161A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14023399P 1999-06-22 1999-06-22
PCT/IB2000/000756 WO2000078759A1 (en) 1999-06-22 2000-06-06 Polymorphs of crystalline (2-benzhydryl-1-azabicyclo[2,2,2]oct-3-yl)-(5-isopropyl-2-methoxybenzyl)-ammoniumchloride as nk-1 receptor antagonists

Publications (1)

Publication Number Publication Date
IS6161A true IS6161A (is) 2001-11-13

Family

ID=22490317

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6161A IS6161A (is) 1999-06-22 2001-11-13 Fjölgervingar af kristölluðu (2-benshýdrýl-1-azabísýkló [2,2,2]okt-3-ýl)-(5-ísóprópýl-2-metoxýbensýl)-ammóníumklóríði sem NK-1 viðtaka mótlyf

Country Status (35)

Country Link
US (1) US6262067B1 (is)
EP (1) EP1187834A1 (is)
JP (1) JP2003502425A (is)
KR (1) KR20020030280A (is)
CN (1) CN1390216A (is)
AP (1) AP2001002367A0 (is)
AR (1) AR024411A1 (is)
AU (1) AU767336B2 (is)
BG (1) BG106205A (is)
BR (1) BR0011835A (is)
CA (1) CA2375265A1 (is)
CO (1) CO5190663A1 (is)
CZ (1) CZ20014458A3 (is)
DZ (1) DZ3055A1 (is)
EA (1) EA004264B1 (is)
EC (1) ECSP003538A (is)
EE (1) EE200100698A (is)
HR (1) HRP20010920A2 (is)
HU (1) HUP0201694A3 (is)
IL (1) IL146410A0 (is)
IS (1) IS6161A (is)
MA (1) MA26744A1 (is)
MX (1) MXPA02000033A (is)
NO (1) NO20016187D0 (is)
NZ (1) NZ515348A (is)
OA (1) OA11952A (is)
PA (1) PA8496701A1 (is)
PE (1) PE20010322A1 (is)
PL (1) PL352899A1 (is)
SK (1) SK18672001A3 (is)
TN (1) TNSN00137A1 (is)
TR (1) TR200103688T2 (is)
UY (1) UY26211A1 (is)
WO (1) WO2000078759A1 (is)
ZA (1) ZA200110387B (is)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387925B1 (en) * 1999-06-01 2002-05-14 Pfizer Inc. Polymorphs of a crystalline azo-bicyclo (2.2.2) oct-3-yl amine citrate and their pharmaceutical compositions
US6939873B2 (en) 2000-07-26 2005-09-06 Taro Pharmaceuticals Industries Limited Non-sedating barbituric acid derivatives
US6756379B2 (en) * 2001-07-26 2004-06-29 Taro Pharmaceutical Industries Ltd. Non-sedating barbiturate compounds as neuroprotective agents
US7683071B2 (en) * 2000-07-26 2010-03-23 Taro Pharmaceuticals Industries Ltd. Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
JP2006503859A (ja) * 2002-10-04 2006-02-02 メルク シャープ エンド ドーム リミテッド 受容体拮抗薬としてのアザ二環式スピロエーテル誘導体
EP2156839A1 (en) 2002-12-11 2010-02-24 Taro Pharmaceutical Industries Ltd. Method of treating movement disorders using barbituric acid derivatives
WO2006003651A2 (en) * 2004-07-02 2006-01-12 Taro Pharmaceutical Industries, Ltd A process for preparing 1-methoxymethyl-5,5-diphenylbarbituric acid
WO2008066704A2 (en) * 2006-11-14 2008-06-05 Taro Pharmaceuticals North America, Inc. Method of improving bioavailability for non-sedating barbiturates
UA102128C2 (en) * 2008-12-05 2013-06-10 Х. Луннбек А/С Nalmefene hydrochloride dihydrate
TWI866977B (zh) * 2019-06-03 2024-12-21 以色列商以色列耶路撒冷希伯來大學伊索研究發展有限公司 吡唑化合物之非吸濕性結晶鹽及其醫藥組合物及用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists
SK278788B6 (sk) * 1991-05-31 1998-02-04 Pfizer Inc. Chinuklidínové deriváty, spôsob ich prípravy a pou
KR950704311A (ko) * 1992-11-12 1995-11-17 알렌 제이. 스피겔 물질 p 길항체로서의 퀴누클리딘 유도체(quinuclidine derivative as substance p antagonist)
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis

Also Published As

Publication number Publication date
TNSN00137A1 (fr) 2002-05-30
EA004264B1 (ru) 2004-02-26
EA200101179A1 (ru) 2002-06-27
WO2000078759A1 (en) 2000-12-28
HUP0201694A2 (en) 2002-09-28
AU4774500A (en) 2001-01-09
PL352899A1 (en) 2003-09-22
CZ20014458A3 (cs) 2002-03-13
NZ515348A (en) 2003-07-25
BG106205A (bg) 2002-07-31
UY26211A1 (es) 2001-01-31
HRP20010920A2 (en) 2003-02-28
IL146410A0 (en) 2002-07-25
SK18672001A3 (sk) 2002-08-06
US6262067B1 (en) 2001-07-17
JP2003502425A (ja) 2003-01-21
MXPA02000033A (es) 2002-07-02
OA11952A (en) 2006-04-13
CA2375265A1 (en) 2000-12-28
EE200100698A (et) 2003-02-17
AR024411A1 (es) 2002-10-02
HUP0201694A3 (en) 2002-10-28
CO5190663A1 (es) 2002-08-29
DZ3055A1 (fr) 2004-03-27
PA8496701A1 (es) 2002-07-30
TR200103688T2 (tr) 2002-12-23
NO20016187L (no) 2001-12-18
CN1390216A (zh) 2003-01-08
AU767336B2 (en) 2003-11-06
ECSP003538A (es) 2002-01-25
EP1187834A1 (en) 2002-03-20
BR0011835A (pt) 2002-03-05
KR20020030280A (ko) 2002-04-24
AP2001002367A0 (en) 2001-12-31
MA26744A1 (fr) 2004-12-20
PE20010322A1 (es) 2001-03-14
NO20016187D0 (no) 2001-12-18
ZA200110387B (en) 2002-12-19

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