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IS5958A - 3, 4, 5-þrístaðgengin arýlnítronefnasambönd og lyfjablöndur sem slík efnasambönd eru í - Google Patents

3, 4, 5-þrístaðgengin arýlnítronefnasambönd og lyfjablöndur sem slík efnasambönd eru í

Info

Publication number
IS5958A
IS5958A IS5958A IS5958A IS5958A IS 5958 A IS5958 A IS 5958A IS 5958 A IS5958 A IS 5958A IS 5958 A IS5958 A IS 5958A IS 5958 A IS5958 A IS 5958A
Authority
IS
Iceland
Prior art keywords
compounds
arylonitrone
triple
accessible
pharmaceutical compositions
Prior art date
Application number
IS5958A
Other languages
English (en)
Inventor
L. Waterbury David
L. Wilcox Allan
M. Carney John
Mavandadi Farah
Danielzadeh Albert
Original Assignee
Renovis, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Renovis, Inc. filed Critical Renovis, Inc.
Publication of IS5958A publication Critical patent/IS5958A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IS5958A 1998-12-02 2001-05-31 3, 4, 5-þrístaðgengin arýlnítronefnasambönd og lyfjablöndur sem slík efnasambönd eru í IS5958A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11054198P 1998-12-02 1998-12-02
PCT/US1999/028479 WO2000032567A1 (en) 1998-12-02 1999-12-01 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same

Publications (1)

Publication Number Publication Date
IS5958A true IS5958A (is) 2001-05-31

Family

ID=22333591

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5958A IS5958A (is) 1998-12-02 2001-05-31 3, 4, 5-þrístaðgengin arýlnítronefnasambönd og lyfjablöndur sem slík efnasambönd eru í

Country Status (21)

Country Link
US (1) US6342523B1 (is)
EP (1) EP1135367A1 (is)
JP (1) JP2002531435A (is)
KR (1) KR20010087407A (is)
CN (1) CN1334800A (is)
AU (1) AU773343B2 (is)
BR (1) BR9915886A (is)
CA (1) CA2353402A1 (is)
CZ (1) CZ20011830A3 (is)
EA (1) EA004931B1 (is)
HK (1) HK1044147A1 (is)
HU (1) HUP0104576A3 (is)
IL (1) IL143506A0 (is)
IS (1) IS5958A (is)
NO (1) NO20012727L (is)
NZ (1) NZ512032A (is)
PL (1) PL349916A1 (is)
SK (1) SK7502001A3 (is)
UA (1) UA66401C2 (is)
WO (1) WO2000032567A1 (is)
ZA (1) ZA200104378B (is)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050107366A1 (en) * 1991-06-18 2005-05-19 Carney John M. Spin trapping pharmaceutical compositions and methods for use thereof
US6730700B2 (en) * 1998-12-02 2004-05-04 Renovis, Inc. 3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same
AU2002253857A1 (en) * 2001-01-08 2002-09-04 Centaur Pharmaceuticals, Inc. Use of aryl nitrone compounds in methods for treating neuropathic pain
US20030045461A1 (en) * 2001-09-06 2003-03-06 Jen-Chang Hsia Composition and methods of esterified nitroxides gated with carboxylic acids
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
TW200404069A (en) * 2002-06-28 2004-03-16 Upjohn Co Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent
US7115666B2 (en) * 2002-10-15 2006-10-03 Renovis, Inc. Nitrone compounds, pharmaceutical compositions containing the same and methods for treating inflammation and neuropathic pain
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds
US20050215646A1 (en) * 2004-03-09 2005-09-29 Renovis, Inc. Methods for treating multiple sclerosis and pharmaceutical compositions therefor
CN104622879A (zh) * 2008-02-12 2015-05-20 托斯克公司 减少毒性的多柔比星助剂及其使用方法
CN101468970B (zh) * 2008-04-25 2011-05-11 暨南大学 一种硝酮类化合物及其制备方法和在制药中的应用
CN102311396B (zh) * 2010-07-05 2015-01-07 暨南大学 一种吡嗪类衍生物和其制备方法及在制药中的应用
US9156862B2 (en) 2011-11-01 2015-10-13 The Florida International University Board Of Trustees Silylated azulenyl nitrone spin traps as chromotropic superoxide detectors
CN104803880B (zh) * 2014-01-23 2017-11-21 广州喜鹊医药有限公司 一种具有神经保护作用的化合物及其制备方法和应用
CN109438288B (zh) * 2018-10-22 2021-05-07 河南中医药大学 一种n-硝酮取代芳香酰胺衍生物及其制备方法
US20240165148A1 (en) 2021-03-15 2024-05-23 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224340A (en) 1977-10-06 1980-09-23 William H. Rorer, Inc. Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds
GB2137619A (en) * 1983-03-30 1984-10-10 Gerald Scott Nitrone compounds and stabilised rubber compositions containing them
GB8813339D0 (en) * 1988-06-06 1988-07-13 Sandoz Ltd Improvements in/relating to organic compounds
FI93954C (fi) 1988-11-29 1995-06-26 Warner Lambert Co Menetelmä lääkeaineina käyttökelpoisten 3,5-di-tert-butyyli-4-hydroksifenyylisubstituoitujen 1,2,4- ja 1,3,4-tiadiatsolien sekä oksadiatsolien ja triatsolien valmistamiseksi
KR960008230B1 (ko) * 1989-10-17 1996-06-21 윌리엄 쥐.씨먼 중추신경계의 산화적 손상에 관련된 질병들을 억제하기 위한 조성물들
US5622994A (en) 1989-10-17 1997-04-22 Oklahoma Medical Research Foundation Spin trapping pharmaceutical compositions and methods for use thereof
US5025032A (en) * 1989-10-17 1991-06-18 Oklahoma Medical Research Foundation Phenyl butyl nitrone compositions and methods for treatment of oxidative tissue damage
US5036097A (en) 1989-10-17 1991-07-30 Oklahoma Medical Research Foundation Phenylbutyl nitrone compositions and methods for prevention of gastric ulceration
US5143928A (en) 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
US6002001A (en) 1991-06-18 1999-12-14 Oklahoma Medical Research Foundation Spin trapping pharmaceutical compositions and methods for use thereof
US5270319A (en) 1991-09-09 1993-12-14 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents
US5215986A (en) 1992-06-01 1993-06-01 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene oxaza heterocycles
US5840746A (en) 1993-06-24 1998-11-24 Merck Frosst Canada, Inc. Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases
US5455272A (en) 1993-10-22 1995-10-03 Oklahoma Medical Research Foundation Spin trap nitronyl hindered phenols
US5488145A (en) 1993-12-23 1996-01-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
NZ332561A (en) 1996-04-23 2001-01-26 Centaur Pharmaceuticals Inc Compositions comprising a nitrone compound for use in treating ocular inflammation
IL128070A0 (en) 1996-07-19 1999-11-30 Centaur Pharmaceuticals Inc Furan nitrone compounds
TW429241B (en) * 1996-09-26 2001-04-11 Sumitomo Pharma Nitrone derivatives
US5994396A (en) 1997-08-18 1999-11-30 Centaur Pharmaceuticals, Inc. Furansulfonic acid derivatives and pharmaceutical compositions containing the same
US6046232A (en) 1997-10-17 2000-04-04 Centaur Pharmaceuticals, Inc. α-aryl-N-alkylnitrones and pharmaceutical compositions containing the same
US5998469A (en) 1998-01-16 1999-12-07 Centaur Pharmaceuticals, Inc. Thioether furan nitrone compounds
JP2002509147A (ja) 1998-01-16 2002-03-26 センター ファーマシューティカルズ， インコーポレイテッド チオフェンニトロン化合物
CA2323490A1 (en) 1998-03-13 1999-09-16 Lowell D. Waterbury Inhibition of angiogenesis
NZ508176A (en) 1998-05-19 2004-01-30 Centaur Pharmaceuticals Inc Aryl nitrone therapeutics and their use for the treatment of inflammatory bowel disease

Also Published As

Publication number Publication date
NO20012727L (no) 2001-07-26
JP2002531435A (ja) 2002-09-24
EA004931B1 (ru) 2004-10-28
KR20010087407A (ko) 2001-09-15
NO20012727D0 (no) 2001-06-01
AU1929800A (en) 2000-06-19
ZA200104378B (en) 2002-08-28
BR9915886A (pt) 2001-08-21
SK7502001A3 (en) 2002-02-05
IL143506A0 (en) 2002-04-21
CN1334800A (zh) 2002-02-06
NZ512032A (en) 2004-02-27
CA2353402A1 (en) 2000-06-08
PL349916A1 (en) 2002-10-07
AU773343B2 (en) 2004-05-20
HUP0104576A2 (hu) 2002-05-29
HK1044147A1 (zh) 2002-10-11
EA200100607A1 (ru) 2001-12-24
US6342523B1 (en) 2002-01-29
EP1135367A1 (en) 2001-09-26
HUP0104576A3 (en) 2002-11-28
CZ20011830A3 (cs) 2001-10-17
UA66401C2 (en) 2004-05-17
WO2000032567A1 (en) 2000-06-08

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