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IS5236A - Amidínafleiður sem hemlar gegn nituroxíðsyntasa - Google Patents

Amidínafleiður sem hemlar gegn nituroxíðsyntasa

Info

Publication number
IS5236A
IS5236A IS5236A IS5236A IS5236A IS 5236 A IS5236 A IS 5236A IS 5236 A IS5236 A IS 5236A IS 5236 A IS5236 A IS 5236A IS 5236 A IS5236 A IS 5236A
Authority
IS
Iceland
Prior art keywords
nitric oxide
oxide synthase
amidine derivatives
inhibit nitric
inhibit
Prior art date
Application number
IS5236A
Other languages
English (en)
Inventor
Macdonald James
Matz James
Shakespeare William
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of IS5236A publication Critical patent/IS5236A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS5236A 1997-05-05 1999-11-01 Amidínafleiður sem hemlar gegn nituroxíðsyntasa IS5236A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9701681A SE9701681D0 (sv) 1997-05-05 1997-05-05 New compounds
PCT/SE1998/000785 WO1998050382A1 (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase

Publications (1)

Publication Number Publication Date
IS5236A true IS5236A (is) 1999-11-01

Family

ID=20406835

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5236A IS5236A (is) 1997-05-05 1999-11-01 Amidínafleiður sem hemlar gegn nituroxíðsyntasa

Country Status (25)

Country Link
US (1) US6489322B1 (is)
EP (1) EP0983268B1 (is)
JP (1) JP2001523262A (is)
KR (1) KR20010012228A (is)
CN (1) CN1255131A (is)
AR (1) AR012601A1 (is)
AT (1) ATE221065T1 (is)
AU (1) AU734391B2 (is)
BR (1) BR9809218A (is)
CA (1) CA2288333A1 (is)
DE (1) DE69806750T2 (is)
EE (1) EE9900474A (is)
HU (1) HUP0001873A3 (is)
ID (1) ID22885A (is)
IL (1) IL132678A0 (is)
IS (1) IS5236A (is)
MX (1) MXPA99009882A (is)
NO (1) NO995403L (is)
NZ (1) NZ500675A (is)
PL (1) PL336853A1 (is)
SE (1) SE9701681D0 (is)
SK (1) SK140599A3 (is)
TR (1) TR199902720T2 (is)
WO (1) WO1998050382A1 (is)
ZA (1) ZA983736B (is)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
JPWO2006118104A1 (ja) * 2005-04-26 2008-12-18 株式会社東芝 白色ｌｅｄおよびそれを用いたバックライト並びに液晶表示装置
JP2009501705A (ja) * 2005-07-05 2009-01-22 アストラゼネカ・アクチエボラーグ 新規化合物、その製造方法、中間体、医薬組成物、並びにアルツハイマー病、認知障害、統合失調症に伴う認識機能障害、肥満及びパーキンソン病のような５−ｈｔ６介在疾患の治療におけるそれらの使用
MY148644A (en) 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
EP2077846B1 (en) * 2006-11-02 2011-10-12 Piramal Life Sciences Limited Benzoxazepine compounds, their preparation and use
US8247403B2 (en) 2007-03-07 2012-08-21 Takeda Pharmaceutical Company Limited Benzoxazepine derivatives and use thereof
WO2008144483A2 (en) * 2007-05-18 2008-11-27 Armgo Pharma, Inc. Agents for treating disorders involving modulation of ryanodine receptors
US8648066B2 (en) * 2009-05-22 2014-02-11 Exelixis, Inc. Benzoxazepines as inhibitors of PI3K/mTOR and methods of their use and manufacture

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0713483B1 (en) 1993-08-12 2003-01-15 AstraZeneca AB Amidine derivatives with nitric oxide synthetase activities
AU7705694A (en) 1993-10-04 1995-05-01 Glaxo Wellcome House Substituted urea and isothiourea derivatives as no synthase inhibitors
KR100342275B1 (ko) 1993-10-21 2002-12-05 지.디. 썰 엘엘씨 산화질소신타제저해제로서유용한아미디노유도체
US5807886A (en) * 1994-05-07 1998-09-15 Astra Aktiebolag Bicyclic amidine dervatives as inhibitors of nitric oxide synthetase
TW397812B (en) 1995-02-11 2000-07-11 Astra Ab Bicyclic isothiourea derivatives useful in therapy
SK281442B6 (sk) * 1995-08-10 2001-03-12 Astra Aktiebolag Bicyklické amidínové deriváty, spôsob ich prípravy, farmaceutické kompozície s ich obsahom a ich použitie
TW458978B (en) 1995-11-07 2001-10-11 Astra Ab Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase

Also Published As

Publication number Publication date
CN1255131A (zh) 2000-05-31
ID22885A (id) 1999-12-16
NO995403D0 (no) 1999-11-04
AU7459898A (en) 1998-11-27
JP2001523262A (ja) 2001-11-20
KR20010012228A (ko) 2001-02-15
EP0983268B1 (en) 2002-07-24
AU734391B2 (en) 2001-06-14
BR9809218A (pt) 2000-06-27
MXPA99009882A (es) 2005-11-22
NO995403L (no) 2000-01-05
CA2288333A1 (en) 1998-11-12
US6489322B1 (en) 2002-12-03
PL336853A1 (en) 2000-07-17
AR012601A1 (es) 2000-11-08
DE69806750D1 (de) 2002-08-29
IL132678A0 (en) 2001-03-19
SK140599A3 (en) 2000-06-12
DE69806750T2 (de) 2003-03-06
SE9701681D0 (sv) 1997-05-05
WO1998050382A1 (en) 1998-11-12
TR199902720T2 (xx) 2000-02-21
EP0983268A1 (en) 2000-03-08
ZA983736B (en) 1998-11-05
EE9900474A (et) 2000-06-15
HUP0001873A2 (hu) 2001-01-29
HUP0001873A3 (en) 2001-12-28
NZ500675A (en) 2001-05-25
ATE221065T1 (de) 2002-08-15

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