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IS3570A7 - Aðferð við framleiðslu á efnasamsetningu sem gerð er úr uppbótarefnum (3-substistuted) og kristalsamböndum (2-oxindole) - Google Patents

Aðferð við framleiðslu á efnasamsetningu sem gerð er úr uppbótarefnum (3-substistuted) og kristalsamböndum (2-oxindole)

Info

Publication number
IS3570A7
IS3570A7 IS3570A IS3570A IS3570A7 IS 3570 A7 IS3570 A7 IS 3570A7 IS 3570 A IS3570 A IS 3570A IS 3570 A IS3570 A IS 3570A IS 3570 A7 IS3570 A7 IS 3570A7
Authority
IS
Iceland
Prior art keywords
oxindole
additives
substituted
preparation
chemical composition
Prior art date
Application number
IS3570A
Other languages
English (en)
Other versions
IS1636B (is
Inventor
Jacob Ehrgott Frederick
Joseph Goddard Carl
Richard Schulte Gary
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of IS3570A7 publication Critical patent/IS3570A7/is
Publication of IS1636B publication Critical patent/IS1636B/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IS3570A 1989-04-18 1990-04-09 Aðferð við framleiðslu á efnasamsetningu sem gerðer úr uppbótarefnum (3-substistuted) og kristalsamböndum (2-oxindole) IS1636B (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34011389A 1989-04-18 1989-04-18

Publications (2)

Publication Number Publication Date
IS3570A7 true IS3570A7 (is) 1990-10-19
IS1636B IS1636B (is) 1996-09-20

Family

ID=23331948

Family Applications (1)

Application Number Title Priority Date Filing Date
IS3570A IS1636B (is) 1989-04-18 1990-04-09 Aðferð við framleiðslu á efnasamsetningu sem gerðer úr uppbótarefnum (3-substistuted) og kristalsamböndum (2-oxindole)

Country Status (33)

Country Link
US (4) US5047554A (is)
EP (1) EP0393936B1 (is)
JP (2) JP2506478B2 (is)
KR (1) KR920006394B1 (is)
CN (1) CN1022832C (is)
AP (1) AP142A (is)
AT (1) ATE118767T1 (is)
AU (1) AU633767B2 (is)
BG (1) BG60646B1 (is)
CA (1) CA2014467C (is)
CZ (1) CZ284340B6 (is)
DD (1) DD293822A5 (is)
DE (1) DE69017066T2 (is)
DK (1) DK0393936T3 (is)
EG (1) EG19122A (is)
ES (1) ES2068334T3 (is)
FI (1) FI106378B (is)
GR (1) GR3015811T3 (is)
HU (2) HUT58314A (is)
IE (1) IE65091B1 (is)
IL (3) IL94047A (is)
IS (1) IS1636B (is)
MA (1) MA21808A1 (is)
MX (1) MX20359A (is)
NO (1) NO176759C (is)
NZ (1) NZ233320A (is)
OA (1) OA09205A (is)
PL (2) PL163951B1 (is)
PT (1) PT93785B (is)
RO (1) RO106402B1 (is)
RU (2) RU2039042C1 (is)
YU (1) YU47588B (is)
ZA (1) ZA902871B (is)

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Also Published As

Publication number Publication date
MX20359A (es) 1994-02-28
IS1636B (is) 1996-09-20
JP2506478B2 (ja) 1996-06-12
IL94047A (en) 1995-10-31
NZ233320A (en) 1991-09-25
AU621477B2 (en) 1992-03-12
CZ284340B6 (cs) 1998-10-14
RU2039042C1 (ru) 1995-07-09
YU75590A (sh) 1992-07-20
JP2581525B2 (ja) 1997-02-12
DE69017066T2 (de) 1995-06-14
EP0393936B1 (en) 1995-02-22
US6174883B1 (en) 2001-01-16
DE69017066D1 (de) 1995-03-30
GR3015811T3 (en) 1995-07-31
IE65091B1 (en) 1995-10-04
BG60646B1 (bg) 1995-11-30
PL163941B1 (pl) 1994-05-31
FI901915A0 (fi) 1990-04-17
KR920006394B1 (ko) 1992-08-06
AP9000175A0 (en) 1990-04-30
ATE118767T1 (de) 1995-03-15
CN1046525A (zh) 1990-10-31
ES2068334T3 (es) 1995-04-16
EP0393936A1 (en) 1990-10-24
NO901684D0 (no) 1990-04-17
US5919809A (en) 1999-07-06
IE901360L (en) 1990-10-18
HUT58314A (en) 1992-02-28
NO176759C (no) 1995-05-24
NO176759B (no) 1995-02-13
FI106378B (fi) 2001-01-31
ZA902871B (en) 1991-11-27
US5290802A (en) 1994-03-01
DK0393936T3 (da) 1995-06-26
AU633767B2 (en) 1993-02-04
AU1051092A (en) 1992-04-09
RU2073671C1 (ru) 1997-02-20
PT93785B (pt) 1996-09-30
HU902462D0 (en) 1990-08-28
AU5362690A (en) 1990-11-22
MA21808A1 (fr) 1990-12-31
PT93785A (pt) 1990-11-20
IL110173A0 (en) 1994-10-07
PL284817A1 (en) 1991-03-25
OA09205A (en) 1992-06-30
BG91773A (bg) 1993-12-24
CA2014467C (en) 2000-02-08
NO901684L (no) 1990-10-19
PL287812A1 (en) 1991-07-15
YU47588B (sh) 1995-10-24
DD293822A5 (de) 1991-09-12
CA2014467A1 (en) 1990-10-18
JPH07118261A (ja) 1995-05-09
RO106402B1 (ro) 1993-04-30
KR900016189A (ko) 1990-11-12
PL163951B1 (pl) 1994-05-31
IL110173A (en) 1997-06-10
US5047554A (en) 1991-09-10
JPH02292258A (ja) 1990-12-03
CN1022832C (zh) 1993-11-24
HU211150A9 (en) 1995-10-30
CZ184890A3 (cs) 1998-07-15
EG19122A (en) 1994-07-30
AP142A (en) 1991-09-26
IL94047A0 (en) 1991-01-31

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