IS2986B - Nýr tilbúinn fjölræsivaki til að nota við meðferð á manneskjum - Google Patents
Nýr tilbúinn fjölræsivaki til að nota við meðferð á manneskjumInfo
- Publication number
- IS2986B IS2986B IS7083A IS7083A IS2986B IS 2986 B IS2986 B IS 2986B IS 7083 A IS7083 A IS 7083A IS 7083 A IS7083 A IS 7083A IS 2986 B IS2986 B IS 2986B
- Authority
- IS
- Iceland
- Prior art keywords
- human therapy
- new synthetic
- synthetic multilayer
- multilayer agent
- agent
- Prior art date
Links
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
- H04L51/00—User-to-user messaging in packet-switching networks, transmitted according to store-and-forward or real-time protocols, e.g. e-mail
- H04L51/06—Message adaptation to terminal or network requirements
- H04L51/063—Content adaptation, e.g. replacement of unsuitable content
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
- H04L51/00—User-to-user messaging in packet-switching networks, transmitted according to store-and-forward or real-time protocols, e.g. e-mail
- H04L51/58—Message adaptation for wireless communication
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Computer Networks & Wireless Communication (AREA)
- Signal Processing (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0102327A SE0102327D0 (sv) | 2001-06-28 | 2001-06-28 | A novel engineered superantigen for human therapy |
| PCT/SE2002/001188 WO2003002143A1 (en) | 2001-06-28 | 2002-06-19 | A novel engineered superantigen for human therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IS7083A IS7083A (is) | 2003-12-18 |
| IS2986B true IS2986B (is) | 2017-09-15 |
Family
ID=20284677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7083A IS2986B (is) | 2001-06-28 | 2003-12-18 | Nýr tilbúinn fjölræsivaki til að nota við meðferð á manneskjum |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US7125554B2 (is) |
| EP (1) | EP1406657B1 (is) |
| JP (1) | JP4523773B2 (is) |
| KR (1) | KR100961054B1 (is) |
| CN (1) | CN1522156B (is) |
| BG (1) | BG66321B1 (is) |
| BR (1) | BRPI0210568B8 (is) |
| CA (1) | CA2451847C (is) |
| CZ (1) | CZ307180B6 (is) |
| DK (1) | DK1406657T3 (is) |
| EE (1) | EE05475B1 (is) |
| ES (1) | ES2564041T3 (is) |
| HR (1) | HRP20031054B1 (is) |
| HU (1) | HUP0400313A3 (is) |
| IL (2) | IL159562A0 (is) |
| IS (1) | IS2986B (is) |
| MX (1) | MXPA03011761A (is) |
| NO (1) | NO333676B1 (is) |
| NZ (1) | NZ529827A (is) |
| PL (1) | PL216516B1 (is) |
| RS (1) | RS52581B (is) |
| RU (1) | RU2307837C2 (is) |
| SE (1) | SE0102327D0 (is) |
| SK (1) | SK16112003A3 (is) |
| UA (1) | UA85993C2 (is) |
| WO (1) | WO2003002143A1 (is) |
| ZA (1) | ZA200309150B (is) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9402430L (sv) * | 1994-07-11 | 1996-01-12 | Pharmacia Ab | Konjugat mellan modifierat superantigen och en målsökande förening samt användning av konjugaten |
| TW517061B (en) * | 1996-03-29 | 2003-01-11 | Pharmacia & Amp Upjohn Ab | Modified/chimeric superantigens and their use |
| CA2296798A1 (en) * | 1997-07-21 | 1999-02-04 | Morten Soegaard | Directed cytolysis of target cells, agents and compositions causing cytolysis, and compounds that can be used to produce the agents |
| US7491402B2 (en) * | 1998-12-24 | 2009-02-17 | Auckland Uniservices Limited | Superantigens SMEZ-2, SPE-G, SPE-H and SPE-J and uses thereof |
| US20040214783A1 (en) * | 2002-05-08 | 2004-10-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| SE0102327D0 (sv) * | 2001-06-28 | 2001-06-28 | Active Biotech Ab | A novel engineered superantigen for human therapy |
| WO2004016225A2 (en) * | 2002-08-19 | 2004-02-26 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| GB0126378D0 (en) * | 2001-11-02 | 2002-01-02 | Oxford Biomedica Ltd | Antigen |
| DE602004026039D1 (de) * | 2003-03-28 | 2010-04-29 | Kowa Co | Seb-modifikation und diese enthaltendes vorbeugendes mittel/heilmittel gegen krankheiten mit einer immunanomalität |
| SE0402025D0 (sv) * | 2004-08-13 | 2004-08-13 | Active Biotech Ab | Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent |
| US20080274133A1 (en) * | 2004-11-18 | 2008-11-06 | Avidex Ltd. | Soluble Bifunctional Proteins |
| GB0427585D0 (en) * | 2004-12-16 | 2005-01-19 | Avidex Ltd | Assay |
| US8455188B2 (en) * | 2007-01-26 | 2013-06-04 | University Of Louisville Research Foundation, Inc. | Modification of exosomal components for use as a vaccine |
| GB0822836D0 (en) * | 2008-12-15 | 2009-01-21 | Oxford Biomedica Ltd | Method |
| CA2807552A1 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| DE19177059T1 (de) | 2010-10-01 | 2021-10-07 | Modernatx, Inc. | N1-methyl-pseudouracile enthältendes ribonucleinsäuren sowie ihre verwendungen |
| JP2014511687A (ja) | 2011-03-31 | 2014-05-19 | モデルナ セラピューティクス インコーポレイテッド | 工学操作された核酸の送達および製剤 |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| CA2846432A1 (en) | 2011-09-23 | 2013-03-28 | Amgen Research (Munich) Gmbh | Bispecific binding molecules for 5t4 and cd3 |
| HUE057725T2 (hu) | 2011-10-03 | 2022-06-28 | Modernatx Inc | Módosított nukleozidok, nukleotidok és nukleinsavak és ezek felhasználása |
| CN102516392B (zh) * | 2011-11-25 | 2014-05-28 | 孙嘉琳 | 一种癌靶向超抗原融合蛋白及制备方法及用途 |
| HRP20220717T1 (hr) | 2011-12-16 | 2022-07-22 | Modernatx, Inc. | Modificirani pripravci mrna |
| US9303079B2 (en) | 2012-04-02 | 2016-04-05 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| JP2015516143A (ja) | 2012-04-02 | 2015-06-08 | モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. | ヒト疾患に関連するタンパク質の産生のための修飾ポリヌクレオチド |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| SMT202200337T1 (it) | 2012-11-26 | 2022-09-14 | Modernatx Inc | Rna modificato al livello del terminale |
| CN103965302B (zh) * | 2013-01-29 | 2019-05-28 | 军事科学院军事医学研究院微生物流行病研究所 | 一种重组超抗原seb突变体,其制备方法及应用 |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| EP3052106A4 (en) | 2013-09-30 | 2017-07-19 | ModernaTX, Inc. | Polynucleotides encoding immune modulating polypeptides |
| WO2015051214A1 (en) | 2013-10-03 | 2015-04-09 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
| JP7161938B2 (ja) | 2016-01-10 | 2022-10-27 | ネオティーエックス セラピューティクス リミテッド | スーパー抗原媒介性癌免疫療法の能力を増強するための方法および組成物 |
| CA3069747A1 (en) * | 2017-07-27 | 2019-01-31 | Mohammad Javad Aman | Immunogenic composition comprising a fusion peptide derived from superantigen toxoids |
| JP7643730B2 (ja) | 2019-05-14 | 2025-03-11 | ザ・ユニバーシティ・オブ・シカゴ | ブドウ球菌(Staphylococcus)プロテインA(SpA)変種を含む方法および組成物 |
| EP3969043A1 (en) | 2019-05-15 | 2022-03-23 | Neotx Therapeutics Ltd. | Cancer treatment |
| KR20220150353A (ko) | 2020-03-05 | 2022-11-10 | 네오티엑스 테라퓨틱스 엘티디. | 면역 세포를 사용하여 암을 치료하기 위한 방법 및 조성물 |
| US20230114276A1 (en) * | 2020-03-06 | 2023-04-13 | Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis | Modulating anti-tumor immunity |
| WO2022067255A2 (en) * | 2020-09-28 | 2022-03-31 | Janssen Pharmaceuticals, Inc. | Variant staphylococcus aureus luka and lukb polypeptides and vaccine compositions |
| EP4536278A2 (en) | 2022-06-07 | 2025-04-16 | Actinium Pharmaceuticals, Inc. | Bifunctional chelators and conjugates |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4596792A (en) | 1981-09-04 | 1986-06-24 | The Regents Of The University Of California | Safe vaccine for hepatitis containing polymerized serum albumin |
| JPS5938877A (ja) | 1982-08-30 | 1984-03-02 | Musashi Eng Kk | 紙葉判別方法 |
| US4599230A (en) | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
| US4599231A (en) | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
| US5238808A (en) | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5221605A (en) | 1984-10-31 | 1993-06-22 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US4608251A (en) | 1984-11-09 | 1986-08-26 | Pitman-Moore, Inc. | LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues |
| US4601903A (en) | 1985-05-01 | 1986-07-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease |
| US5284760A (en) | 1989-04-03 | 1994-02-08 | Feinstone Stephen M | Techniques for producing site-directed mutagenesis of cloned DNA |
| US6042837A (en) * | 1989-09-20 | 2000-03-28 | Kalland; Terje | Methods of staphylococcal enterotoxin directed cell-mediated cytotoxicity (SDCC) |
| US6126945A (en) * | 1989-10-03 | 2000-10-03 | Pharmacia Ab | Tumor killing effects of enterotoxins, superantigens, and related compounds |
| US5728388A (en) * | 1989-10-03 | 1998-03-17 | Terman; David S. | Method of cancer treatment |
| EP1129717B2 (en) | 1990-01-17 | 2013-03-06 | TERMAN, David S. | Use of homologues of staphylococcal enterotoxins for cancer treatment |
| US5220007A (en) | 1990-02-15 | 1993-06-15 | The Worcester Foundation For Experimental Biology | Method of site-specific alteration of RNA and production of encoded polypeptides |
| US5149797A (en) | 1990-02-15 | 1992-09-22 | The Worcester Foundation For Experimental Biology | Method of site-specific alteration of rna and production of encoded polypeptides |
| EP0527809B1 (en) | 1990-04-05 | 1995-08-16 | CREA, Roberto | Walk-through mutagenesis |
| US6197299B1 (en) * | 1990-07-20 | 2001-03-06 | Pharmacia & Upjohn Ab | Antibody conjugates |
| US5858363A (en) * | 1990-07-20 | 1999-01-12 | Pharmacia & Upjohn Ab | Target specific antibody-superantigen conjugates and their preparation |
| WO1993024136A1 (en) | 1991-01-17 | 1993-12-09 | Terman David S | Tumor killing effects of enterotoxins, superantigens, and related compounds |
| US5475085A (en) | 1991-02-07 | 1995-12-12 | Molecumetics, Ltd. | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
| EP0573608A1 (en) | 1991-02-07 | 1993-12-15 | Molecumetics, Ltd. | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
| EP0620858B1 (en) | 1991-12-24 | 2003-05-02 | The President And Fellows Of Harvard College | Site-directed mutagenesis of dna |
| US5389514A (en) | 1992-08-28 | 1995-02-14 | Fox Chase Cancer Center | Method for specifically altering the nucleotide sequence of RNA |
| US5545716A (en) * | 1992-09-08 | 1996-08-13 | University Of Florida | Superantigen agonist and antagonist peptides |
| US5446128A (en) | 1993-06-18 | 1995-08-29 | The Board Of Trustees Of The University Of Illinois | Alpha-helix mimetics and methods relating thereto |
| US5519114A (en) * | 1993-10-29 | 1996-05-21 | University Of Florida Research Foundation, Inc. | Retroviral superantigens, superantigen peptides, and methods of use |
| SE9402430L (sv) * | 1994-07-11 | 1996-01-12 | Pharmacia Ab | Konjugat mellan modifierat superantigen och en målsökande förening samt användning av konjugaten |
| US5935568A (en) | 1995-05-18 | 1999-08-10 | National Jewish Medical & Research Center | Gene therapy for effector cell regulation |
| KR100456594B1 (ko) * | 1995-06-07 | 2005-06-17 | 리전츠 오브 더 유니버스티 오브 미네소타 | 스트렙토코커스독소a의변이체및그의사용방법 |
| US5929237A (en) | 1995-10-27 | 1999-07-27 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| US5840833A (en) | 1995-10-27 | 1998-11-24 | Molecumetics, Ltd | Alpha-helix mimetics and methods relating thereto |
| US5789166A (en) | 1995-12-08 | 1998-08-04 | Stratagene | Circular site-directed mutagenesis |
| SE9601245D0 (sv) * | 1996-03-29 | 1996-03-29 | Pharmacia Ab | Chimeric superantigens and their use |
| WO1997036032A1 (de) | 1996-03-27 | 1997-10-02 | Zellweger Luwa Ag | Verfahren und vorrichtung zur qualitätsüberwachung von garnen |
| WO1997036614A1 (en) * | 1996-03-29 | 1997-10-09 | Terman David S | Polymerized staphylococcal protein a for treatment of diseases |
| TW517061B (en) * | 1996-03-29 | 2003-01-11 | Pharmacia & Amp Upjohn Ab | Modified/chimeric superantigens and their use |
| ATE346860T1 (de) * | 1996-12-06 | 2006-12-15 | Univ Minnesota | Mutanten von streptococcaltoxinen und vefahren zu deren anwendung |
| US6774218B2 (en) * | 1996-12-06 | 2004-08-10 | Regents Of The University Of Minnesota | Mutants of streptococcal toxin C and methods of use |
| ES2260804T3 (es) * | 1996-12-06 | 2006-11-01 | Regents Of The University Of Minnesota | Mutante de la toxina estreptococica c y metodos de uso. |
| US6340461B1 (en) * | 1996-12-17 | 2002-01-22 | David Stephen Terman | Superantigen based methods and compositions for treatment of diseases |
| IL119938A (en) * | 1996-12-30 | 2005-08-31 | Yissum Res Dev Co | Peptides capable of eliciting protective immunity against toxic shock induced by pyrogenic exotoxins or of antagonizing toxin-mediated activation of t cells |
| US6713284B2 (en) * | 1997-06-25 | 2004-03-30 | The United States Of America As Represented By The Secretary Of The Army | Bacterial superantigen vaccines |
| US7087235B2 (en) * | 1997-06-25 | 2006-08-08 | The United States Of America As Represented By The Secretary Of The Army | Fusion protein of streptococcal pyrogenic exotoxins |
| CA2296798A1 (en) | 1997-07-21 | 1999-02-04 | Morten Soegaard | Directed cytolysis of target cells, agents and compositions causing cytolysis, and compounds that can be used to produce the agents |
| RU2115429C1 (ru) * | 1997-07-22 | 1998-07-20 | Закрытое акционерное общество "Фосфосорб" | Рекомбинантный иммунотоксин на основе дифтерийного токсина и интерлейкина-2 (дт 482-il2) и способ его получения |
| WO1999036433A2 (en) * | 1998-01-14 | 1999-07-22 | Morphogenesis, Inc. | Materials and methods for treating oncological disease |
| WO2000002522A2 (en) * | 1998-07-10 | 2000-01-20 | U.S. Medical Research Institute Of Infectious Diseases | Anthrax vaccine |
| US20020177551A1 (en) * | 2000-05-31 | 2002-11-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| US20040214783A1 (en) * | 2002-05-08 | 2004-10-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| US20050112141A1 (en) * | 2000-08-30 | 2005-05-26 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| SE9903895D0 (sv) | 1999-10-28 | 1999-10-28 | Active Biotech Ab | Novel compounds |
| JP2003515323A (ja) | 1999-11-18 | 2003-05-07 | オックスフォード バイオメディカ(ユーケイ)リミテッド | 抗 体 |
| US20030157113A1 (en) * | 1999-12-28 | 2003-08-21 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| US20010046501A1 (en) * | 2000-03-14 | 2001-11-29 | Johnson Howard M. | Superantigen enhancement of specific immune responses |
| JP4283430B2 (ja) * | 2000-09-26 | 2009-06-24 | 株式会社カネカ | エンテロトキシンの吸着材、吸着除去方法および吸着器 |
| EP1349568B1 (en) * | 2000-12-04 | 2009-09-16 | Auckland Uniservices Limited | Immunomodulatory constructs and their uses |
| CN1369550A (zh) * | 2001-02-16 | 2002-09-18 | 沈阳协合集团有限公司 | 一种金黄色葡萄球菌的培养物及其制备方法 |
| SE0102327D0 (sv) * | 2001-06-28 | 2001-06-28 | Active Biotech Ab | A novel engineered superantigen for human therapy |
| BR0313638A (pt) * | 2002-08-21 | 2005-06-21 | Merck Patent Ges Mit Berschron | Epìtopos de células t na enterotoxina b em estafilococos |
| WO2006004620A2 (en) * | 2004-06-29 | 2006-01-12 | Terman David S | Enterotoxin gene cluster (egc) superantigens to treat malignant disease |
| US20060005711A1 (en) | 2004-07-07 | 2006-01-12 | Andrew Olefson | Replaceable filter for a vehicle air conditioning system adapted to scent air |
| SE0402025D0 (sv) | 2004-08-13 | 2004-08-13 | Active Biotech Ab | Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent |
| US20070280905A1 (en) * | 2006-06-01 | 2007-12-06 | Shulin Li | Prognosis and Systemic Therapy for Treating Malignancy |
-
2001
- 2001-06-28 SE SE0102327A patent/SE0102327D0/xx unknown
- 2001-07-06 US US09/900,766 patent/US7125554B2/en not_active Expired - Lifetime
-
2002
- 2002-06-19 ES ES02746240.7T patent/ES2564041T3/es not_active Expired - Lifetime
- 2002-06-19 BR BRPI0210568-3 patent/BRPI0210568B8/pt not_active IP Right Cessation
- 2002-06-19 JP JP2003508382A patent/JP4523773B2/ja not_active Expired - Fee Related
- 2002-06-19 PL PL368048A patent/PL216516B1/pl unknown
- 2002-06-19 EE EEP200400037A patent/EE05475B1/xx not_active IP Right Cessation
- 2002-06-19 WO PCT/SE2002/001188 patent/WO2003002143A1/en not_active Ceased
- 2002-06-19 KR KR1020037016268A patent/KR100961054B1/ko not_active Expired - Fee Related
- 2002-06-19 SK SK1611-2003A patent/SK16112003A3/sk unknown
- 2002-06-19 MX MXPA03011761A patent/MXPA03011761A/es active IP Right Grant
- 2002-06-19 HR HRP20031054AA patent/HRP20031054B1/hr not_active IP Right Cessation
- 2002-06-19 RU RU2004102199/13A patent/RU2307837C2/ru active
- 2002-06-19 IL IL15956202A patent/IL159562A0/xx unknown
- 2002-06-19 CA CA2451847A patent/CA2451847C/en not_active Expired - Lifetime
- 2002-06-19 EP EP02746240.7A patent/EP1406657B1/en not_active Expired - Lifetime
- 2002-06-19 DK DK02746240.7T patent/DK1406657T3/en active
- 2002-06-19 RS YU101503A patent/RS52581B/sr unknown
- 2002-06-19 CZ CZ2003-3559A patent/CZ307180B6/cs not_active IP Right Cessation
- 2002-06-19 NZ NZ529827A patent/NZ529827A/en not_active IP Right Cessation
- 2002-06-19 CN CN028131045A patent/CN1522156B/zh not_active Expired - Lifetime
- 2002-06-19 UA UA2004010601A patent/UA85993C2/ru unknown
- 2002-06-19 HU HU0400313A patent/HUP0400313A3/hu unknown
-
2003
- 2003-11-25 ZA ZA2003/09150A patent/ZA200309150B/en unknown
- 2003-12-18 IS IS7083A patent/IS2986B/is unknown
- 2003-12-22 BG BG108499A patent/BG66321B1/bg unknown
- 2003-12-22 NO NO20035773A patent/NO333676B1/no not_active IP Right Cessation
- 2003-12-24 IL IL159562A patent/IL159562A/en unknown
-
2006
- 2006-11-21 US US11/526,437 patent/US7615225B2/en not_active Expired - Lifetime
-
2009
- 2009-09-28 US US12/568,579 patent/US20100111978A1/en not_active Abandoned
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