IN2012DN06589A - - Google Patents
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- Publication number
- IN2012DN06589A IN2012DN06589A IN6589DEN2012A IN2012DN06589A IN 2012DN06589 A IN2012DN06589 A IN 2012DN06589A IN 6589DEN2012 A IN6589DEN2012 A IN 6589DEN2012A IN 2012DN06589 A IN2012DN06589 A IN 2012DN06589A
- Authority
- IN
- India
- Prior art keywords
- mbl
- sepsis
- infectious diseases
- provides
- bind
- Prior art date
Links
- 102000009112 Mannose-Binding Lectin Human genes 0.000 abstract 3
- 108010087870 Mannose-Binding Lectin Proteins 0.000 abstract 3
- 208000035473 Communicable disease Diseases 0.000 abstract 2
- 206010040047 Sepsis Diseases 0.000 abstract 2
- 244000052769 pathogen Species 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 108010017384 Blood Proteins Proteins 0.000 abstract 1
- 102000004506 Blood Proteins Human genes 0.000 abstract 1
- 208000035049 Blood-Borne Infections Diseases 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 102000004856 Lectins Human genes 0.000 abstract 1
- 108090001090 Lectins Proteins 0.000 abstract 1
- 108700022034 Opsonin Proteins Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 210000005007 innate immune system Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4726—Lectins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56961—Plant cells or fungi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/66—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
- G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
- G01N2333/40—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts from Candida
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
- G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29622210P | 2010-01-19 | 2010-01-19 | |
| PCT/US2011/021603 WO2011090954A2 (fr) | 2010-01-19 | 2011-01-19 | Opsonine obtenue par génie génétique, pour la détection et le traitement de micro-organismes pathogènes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN06589A true IN2012DN06589A (fr) | 2015-10-23 |
Family
ID=44307537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN6589DEN2012 IN2012DN06589A (fr) | 2010-01-19 | 2011-01-19 |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US9150631B2 (fr) |
| EP (1) | EP2526119B1 (fr) |
| JP (5) | JP5959440B2 (fr) |
| CN (1) | CN102947341B (fr) |
| AU (1) | AU2011207626B2 (fr) |
| CA (1) | CA2787376A1 (fr) |
| DK (1) | DK2526119T3 (fr) |
| ES (1) | ES2678143T3 (fr) |
| IN (1) | IN2012DN06589A (fr) |
| SG (2) | SG182577A1 (fr) |
| WO (1) | WO2011090954A2 (fr) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9220831B2 (en) | 2005-10-06 | 2015-12-29 | Children's Medical Center Corporation | Device and method for combined microfluidic-micromagnetic separation of material in continuous flow |
| EP2347774B1 (fr) | 2005-12-13 | 2017-07-26 | The President and Fellows of Harvard College | Echafaudages pour transplantation cellulaire |
| CN102006891B (zh) | 2008-02-13 | 2017-04-26 | 哈佛学院董事会 | 连续的细胞程序化装置 |
| US9156037B2 (en) | 2009-01-15 | 2015-10-13 | Children's Medical Center Corporation | Microfluidic device and uses thereof |
| JP5959440B2 (ja) | 2010-01-19 | 2016-08-02 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 病原体の検出および治療のための改変オプソニン |
| JP6104806B2 (ja) | 2010-10-06 | 2017-03-29 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 材料に基づく細胞治療のための注射可能孔形成性ハイドロゲル |
| US20120263771A1 (en) * | 2011-03-25 | 2012-10-18 | Receptors Llc | Fiber with microbial removal, micro-biocidal, or static growth capability |
| AU2012236128A1 (en) * | 2011-04-01 | 2013-10-31 | Children's Medical Center Corporation | Dialysis like therapeutic (DLT) device |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| US9593160B2 (en) | 2011-07-18 | 2017-03-14 | President And Fellows Of Harvard College | Engineered microbe-targeting molecules and uses thereof |
| US9632085B2 (en) * | 2012-02-29 | 2017-04-25 | President And Fellows Of Harvard College | Rapid antibiotic susceptibility testing |
| PT2838515T (pt) | 2012-04-16 | 2020-02-25 | Harvard College | Composições de sílica mesoporosa para modular respostas imunológicas |
| US20130334120A1 (en) * | 2012-06-15 | 2013-12-19 | President And Fellows Of Harvard College | Fluid cleansing devices and methods of use |
| WO2014014788A2 (fr) * | 2012-07-18 | 2014-01-23 | President And Fellows Of Harvard College | Modification de surfaces pour une répulsion et une liaison ciblée simultanées de fractions désirées |
| EP2976642A4 (fr) | 2013-03-15 | 2016-09-21 | Harvard College | Procédés et compositions pour améliorer la détection et/ou la capture d'une entité cible |
| EP3848044A1 (fr) | 2013-05-21 | 2021-07-14 | President and Fellows of Harvard College | Compositions se liant à l'hème manipulées et leurs utilisations |
| EP3022314B1 (fr) | 2013-07-15 | 2021-05-19 | President and Fellows of Harvard College | Dosages pour l'activité antimicrobienne et leurs applications |
| EP3083658B1 (fr) | 2013-12-18 | 2019-05-08 | President and Fellows of Harvard College | Détection de bacteries gram positif à l'aide de crp |
| DE102014206444A1 (de) * | 2014-04-03 | 2015-10-08 | Siemens Aktiengesellschaft | Verfahren für die Molekulardiagnostik zum Anreichern einer Nukleinsäure aus einer biologischen Probe |
| CN107073090A (zh) | 2014-04-30 | 2017-08-18 | 哈佛学院董事会 | 结合的疫苗装置和杀死癌细胞的方法 |
| WO2016077067A2 (fr) | 2014-10-27 | 2016-05-19 | President And Fellows Of Harvard College | Capture magnétique d'une cible à partir d'un fluide |
| HK1247861A1 (zh) | 2015-01-30 | 2018-10-05 | President And Fellows Of Harvard College | 用於癌症治疗的肿瘤周围和肿瘤内部材料 |
| HK1249452A1 (zh) | 2015-04-10 | 2018-11-02 | President And Fellows Of Harvard College | 免疫细胞捕获装置及其制备和使用方法 |
| CN108289928B (zh) | 2015-08-06 | 2024-09-17 | 哈佛大学校长及研究员协会 | 改进的微生物-结合分子和其用途 |
| EP3349823B1 (fr) | 2015-09-14 | 2022-01-26 | Medisieve Ltd | Appareil de filtration magnétique |
| CN109072197A (zh) | 2016-02-06 | 2018-12-21 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
| JP6854530B2 (ja) * | 2016-02-16 | 2021-04-07 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 病原体ワクチンならびにその製造および使用方法 |
| CA3024490A1 (fr) | 2016-05-16 | 2017-11-23 | President And Fellows Of Harvard College | Couplage de biomolecule aqueuse sur des surfaces activees par plasma de co2 |
| US11555177B2 (en) | 2016-07-13 | 2023-01-17 | President And Fellows Of Harvard College | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same |
| BR112019000748A2 (pt) | 2016-07-28 | 2019-04-24 | Medisieve Ltd | método e misturador magnético |
| CA3032505A1 (fr) | 2016-08-02 | 2018-02-08 | President And Fellows Of Harvard College | Biomateriaux pour moduler des reponses immunitaires |
| WO2019064463A1 (fr) * | 2017-09-28 | 2019-04-04 | 学校法人中部大学 | Procédé et dispositif pour la concentration de virus ou de bactérie par bioaffinité |
| KR102084688B1 (ko) * | 2018-06-18 | 2020-03-04 | 울산과학기술원 | 다중 프로브 혼성화를 이용한 미생물 검출 방법 |
| WO2020061129A1 (fr) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions et procédés de marquage et de modulation de cellules in vitro et in vivo |
| CN110628624B (zh) * | 2019-02-01 | 2022-07-15 | 传鸣(宁波)化学科技有限公司 | 一种磁性微生物捕获材料及微生物捕获方法 |
| CN110294810B (zh) * | 2019-06-26 | 2021-05-04 | 中国疾病预防控制中心传染病预防控制所 | 一种含有人IgG1Fc和甘露聚糖结合凝集素C端的重组蛋白 |
| EP4034148A4 (fr) | 2019-09-23 | 2025-09-10 | Harvard College | Vaccin sans antigène à base de biomatériau et son utilisation |
| WO2021133943A1 (fr) | 2019-12-23 | 2021-07-01 | Miraki Innovation Think Tank Llc | Compositions, dispositifs et procédés de diagnostic et de traitement d'une maladie infectieuse |
| WO2021133963A1 (fr) | 2019-12-23 | 2021-07-01 | Miraki Innovation Think Tank Llc | Préparation d'échantillon et analyse microbienne |
| FI20215508A1 (en) | 2020-04-09 | 2021-10-10 | Niemelae Erik Johan | Mimetic nanoparticles to prevent the spread of new coronaviruses and reduce the rate of infection |
| US12194157B2 (en) | 2020-04-09 | 2025-01-14 | Finncure Oy | Carrier for targeted delivery to a host |
| US12390548B2 (en) | 2020-05-14 | 2025-08-19 | Mehrdad Michael HOGHOOGHI | System and method for protecting a workspace from airborne contaminants |
| CN111675825B (zh) * | 2020-06-09 | 2022-06-24 | 大连工业大学 | 一种附有胰蛋白酶的微孔膜的制备方法及其在蛋白水解中的应用 |
| CA3196472A1 (fr) | 2020-06-12 | 2021-12-16 | Miraki Innovation Think Tank Llc | Dosage a ecoulement lateral pour la detection rapide d'agents pathogenes dans des echantillons |
| US20240001019A1 (en) | 2020-07-31 | 2024-01-04 | Miraki Innovation Think Tank Llc | Mbl-coated substrates having anti-thrombogenic properties |
| US20240199719A1 (en) | 2020-08-28 | 2024-06-20 | Miraki Innovation Think Tank Llc | Therapeutic compositions comprising microbe-targeting molecules and their use in methods of preventing and treating infectious disease |
| WO2022067006A1 (fr) | 2020-09-25 | 2022-03-31 | Miraki Innovation Think Tank Llc | Compositions, dispositifs et méthodes comprenant des molécules ciblant les microbes pour le diagnostic et le traitement d'une maladie infectieuse |
| WO2022072674A1 (fr) | 2020-10-01 | 2022-04-07 | Miraki Innovation Think Tank Llc | Compositions, dispositifs et procédés pour identifier, traiter et prévenir une maladie infectieuse à l'aide de molécules ciblant des microbes |
| WO2022093935A1 (fr) | 2020-10-27 | 2022-05-05 | Miraki Innovation Think Tank Llc | Compositions, systèmes et méthodes de surveillance de pathogènes à l'aide de molécules ciblant des microbes |
| WO2022125632A1 (fr) | 2020-12-08 | 2022-06-16 | Miraki Innovation Think Tank Llc | Cellules exprimant un récepteur antigénique chimérique pour cibler des motifs moléculaires associés aux microbes |
| WO2022151333A1 (fr) * | 2021-01-15 | 2022-07-21 | 传鸣(宁波)化学科技有限公司 | Mélange pour enrichir des micro-organismes et procédé et application |
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