IN2012DN00569A - - Google Patents

Download PDF

Info

Publication number: IN2012DN00569A
Authority: IN; India
Prior art keywords: motilin; maintain; native; activity; transmucosal administration
Prior art date: 2009-07-29

Application number

Other languages

English (en)

Inventor

Sato Seiji

Hanada Takeshi

Wakabayashi Naomi

Masuda Yutaka

Harada Yuriki

Original Assignee

Daiichi Sankyo Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-07-29

Filing date

2010-07-29

Publication date

2015-06-12

2010-07-29 Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd

2015-06-12 Publication of IN2012DN00569A publication Critical patent/IN2012DN00569A/en

Links

LVRVABPNVHYXRT-BQWXUCBYSA-N 52906-92-0 Chemical compound C([C@H](N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O)C(C)C)C1=CC=CC=C1 LVRVABPNVHYXRT-BQWXUCBYSA-N 0.000 abstract 6
101800002372 Motilin Proteins 0.000 abstract 5
102000002419 Motilin Human genes 0.000 abstract 5
150000001875 compounds Chemical class 0.000 abstract 2
238000010521 absorption reaction Methods 0.000 abstract 1
150000001413 amino acids Chemical group 0.000 abstract 1
230000015556 catabolic process Effects 0.000 abstract 1
238000006731 degradation reaction Methods 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000005176 gastrointestinal motility Effects 0.000 abstract 1
238000012423 maintenance Methods 0.000 abstract 1
230000037361 pathway Effects 0.000 abstract 1
230000001766 physiological effect Effects 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1
238000006467 substitution reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/63—Motilins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Nutrition Science (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IN569DEN2012 2009-07-29 2010-07-29 IN2012DN00569A (ru)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2009177107		2009-07-29
PCT/JP2010/062746 WO2011013728A1 (ja)	2009-07-29	2010-07-29	経粘膜吸収性を付与したモチリン類似ペプチド化合物

Publications (1)

Publication Number	Publication Date
IN2012DN00569A true IN2012DN00569A (ru)	2015-06-12

Family

ID=43529381

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IN569DEN2012 IN2012DN00569A (ru)	2009-07-29	2010-07-29

Country Status (21)

Country	Link
US (1)	US8710184B2 (ru)
EP (1)	EP2460826B1 (ru)
JP (1)	JP5647609B2 (ru)
KR (1)	KR101789605B1 (ru)
CN (1)	CN102574904B (ru)
AU (1)	AU2010279076B2 (ru)
BR (1)	BR112012000719A2 (ru)
CA (1)	CA2769013C (ru)
CO (1)	CO6430471A2 (ru)
ES (1)	ES2653523T3 (ru)
IL (1)	IL217781A (ru)
IN (1)	IN2012DN00569A (ru)
MX (1)	MX2012001193A (ru)
MY (1)	MY161842A (ru)
NZ (1)	NZ597777A (ru)
PH (1)	PH12012500169A1 (ru)
RU (1)	RU2540012C2 (ru)
SG (1)	SG177592A1 (ru)
TW (1)	TWI471138B (ru)
WO (1)	WO2011013728A1 (ru)
ZA (1)	ZA201200440B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5670430B2 (ja) *	2010-03-19	2015-02-18	第一三共株式会社	経鼻投与用組成物及びその製造方法
ES2804614T3 (es) *	2013-07-31	2021-02-08	Rinat Neuroscience Corp	Conjugados de polipéptidos manipulados usando transglutaminasa
KR101470793B1 (ko) *	2014-06-30	2014-12-08	순천향대학교 산학협력단	흡수촉진제로서의 펩타이드와 이를 포함하는 조성물
RU2662310C9 (ru) *	2015-12-04	2018-09-21	Виктор Вениаминович Тец	Средство (варианты) и способы восстановления микрофлоры
CN107383169A (zh) *	2017-04-24	2017-11-24	青岛大学	一种具有胃肠运动刺激活性的多肽

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2544348C3 (de)	1975-10-03	1979-12-13	Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen	L-Leucin-13-Motilin, Verfahren zu dessen Herstellung und dasselbe enthaltendes Mittel
JP2753274B2 (ja) *	1988-08-24	1998-05-18	株式会社三和化学研究所	モチリン様ポリペプチドの製法並びにそのための組換えｄｎａ及び発現用プラスミド
JPH0742319B2 (ja) *	1989-01-06	1995-05-10	株式会社三和化学研究所	モチリン様活性を有するポリペプチド及びその用途
EP0378078A1 (en)	1989-01-06	1990-07-18	Sanwa Kagaku Kenkyusho Co., Ltd.	Motilin-like polypeptide and use thereof
DE3922764A1 (de)	1989-07-11	1991-01-17	Babcock Werke Ag	Verfahren und vorrichtung zum abtrennen von feststoff aus einem gas
JPH04364131A (ja) *	1991-04-03	1992-12-16	Sanwa Kagaku Kenkyusho Co Ltd	易吸収性モチリン製剤
US5422341A (en)	1993-08-06	1995-06-06	Ohmeda Pharmaceutical Products Division Inc.	Motilin-like polypeptides with gastrointestinal motor stimulating activity
CA2284733C (en) *	1997-03-24	2010-10-26	Zymogenetics, Inc.	Motilin homologs
US5972939A (en) *	1997-10-28	1999-10-26	Ortho-Mcneil Pharmaceutical, Inc.	Cyclopentene derivatives useful as antagonists of the motilin receptor
SE9802080D0 (sv) *	1998-06-11	1998-06-11	Hellstroem	Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein
US6849714B1 (en) *	1999-05-17	2005-02-01	Conjuchem, Inc.	Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
CA2499211A1 (en) *	1999-05-17	2000-11-23	Conjuchem Inc.	Modified peptides yy and conjugates thereof
US6887470B1 (en) *	1999-09-10	2005-05-03	Conjuchem, Inc.	Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
US6511980B2 (en) *	2000-05-05	2003-01-28	Ortho Mcneil Pharmaceutical, Inc.	Substituted diamine derivatives useful as motilin antagonists
RU2252779C1 (ru) *	2003-09-23	2005-05-27	Институт Молекулярной Генетики Российской Академии Наук (Имг Ран)	Способ профилактики и лечения язв желудочно-кишечного тракта
JP5670430B2 (ja) *	2010-03-19	2015-02-18	第一三共株式会社	経鼻投与用組成物及びその製造方法

2010
- 2010-07-29 BR BR112012000719A patent/BR112012000719A2/pt not_active Application Discontinuation
- 2010-07-29 TW TW99125019A patent/TWI471138B/zh not_active IP Right Cessation
- 2010-07-29 PH PH1/2012/500169A patent/PH12012500169A1/en unknown
- 2010-07-29 EP EP10804474.4A patent/EP2460826B1/en not_active Not-in-force
- 2010-07-29 JP JP2011524821A patent/JP5647609B2/ja not_active Expired - Fee Related
- 2010-07-29 KR KR1020127002980A patent/KR101789605B1/ko not_active Expired - Fee Related
- 2010-07-29 MY MYPI2012000392A patent/MY161842A/en unknown
- 2010-07-29 CA CA2769013A patent/CA2769013C/en not_active Expired - Fee Related
- 2010-07-29 RU RU2012107290/10A patent/RU2540012C2/ru not_active IP Right Cessation
- 2010-07-29 AU AU2010279076A patent/AU2010279076B2/en not_active Ceased
- 2010-07-29 US US13/388,021 patent/US8710184B2/en not_active Expired - Fee Related
- 2010-07-29 MX MX2012001193A patent/MX2012001193A/es active IP Right Grant
- 2010-07-29 CN CN201080043683.9A patent/CN102574904B/zh not_active Expired - Fee Related
- 2010-07-29 WO PCT/JP2010/062746 patent/WO2011013728A1/ja not_active Ceased
- 2010-07-29 IN IN569DEN2012 patent/IN2012DN00569A/en unknown
- 2010-07-29 ES ES10804474.4T patent/ES2653523T3/es active Active
- 2010-07-29 NZ NZ597777A patent/NZ597777A/xx not_active IP Right Cessation
- 2010-07-29 SG SG2012001715A patent/SG177592A1/en unknown
2012
- 2012-01-19 ZA ZA2012/00440A patent/ZA201200440B/en unknown
- 2012-01-26 IL IL217781A patent/IL217781A/en not_active IP Right Cessation
- 2012-02-13 CO CO12024411A patent/CO6430471A2/es active IP Right Grant

Also Published As

Publication number	Publication date
MY161842A (en)	2017-05-15
US8710184B2 (en)	2014-04-29
AU2010279076A1 (en)	2012-03-01
CN102574904A (zh)	2012-07-11
IL217781A0 (en)	2012-03-29
MX2012001193A (es)	2012-03-14
CA2769013C (en)	2015-04-07
US20120129762A1 (en)	2012-05-24
EP2460826B1 (en)	2017-10-18
ZA201200440B (en)	2013-04-24
TW201106964A (en)	2011-03-01
RU2012107290A (ru)	2013-09-10
SG177592A1 (en)	2012-02-28
JP5647609B2 (ja)	2015-01-07
EP2460826A4 (en)	2013-11-20
JPWO2011013728A1 (ja)	2013-01-10
KR20120052274A (ko)	2012-05-23
KR101789605B1 (ko)	2017-10-25
CO6430471A2 (es)	2012-04-30
TWI471138B (zh)	2015-02-01
WO2011013728A1 (ja)	2011-02-03
RU2540012C2 (ru)	2015-01-27
NZ597777A (en)	2013-03-28
EP2460826A1 (en)	2012-06-06
ES2653523T3 (es)	2018-02-07
IL217781A (en)	2015-09-24
AU2010279076B2 (en)	2014-09-25
BR112012000719A2 (pt)	2016-11-01
CN102574904B (zh)	2014-11-26
CA2769013A1 (en)	2011-02-03
PH12012500169A1 (en)	2019-07-10

Publication	Publication Date	Title
MX2011008634A (es)	2011-09-06	Derivados de aminotetralina composiciones farmaceuticas que los contienen y su uso en terapia.
BR112012013431A2 (pt)	2016-04-05	composto, composição farmacêutica e seu uso
EA201171088A1 (ru)	2012-02-28	Лечение дискинезии при различных расстройствах
TNSN08326A1 (en)	2009-12-29	Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
IN2012DN02736A (ru)	2015-09-11
PE20121617A1 (es)	2012-12-14	Derivados de oxazina como inhibidores de bace
CL2013003406A1 (es)	2014-07-25	Compuestos derivados de dolastatina unidos a aminoacidos no naturales; procedimiento de preparacion; composiciones farmaceuticas, útiles en el tratamiento del cancer de mamas.
WO2012020131A3 (en)	2012-04-05	Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
NZ608116A (en)	2014-05-30	Triazine-oxadiazoles
PL2229938T3 (pl)	2012-09-28	Kompozycje ezetymibu
IN2012DN06720A (ru)	2015-10-23
TN2011000437A1 (en)	2013-03-27	Substituted azoanthracene derivatives, pharmaceutical compositions, and methods of use thereof
MX2014009757A (es)	2015-04-08	Derivados de isoindolina, composiciones farmaceuticas que los contienen y su uso en terapia.
UA105229C2 (ru)	2014-04-25	Фармацевтический состав
TN2011000172A1 (en)	2012-12-17	Therapeutic antiviral peptides
IN2012DN03182A (ru)	2015-09-25
WO2011047173A3 (en)	2012-01-12	Pharmaceutical compositions for oral administration
UA105018C2 (ru)	2014-04-10	Акриламидопроизводные, применимые как ингибиторы перехода митохондриальной проницаемости
CR20110255A (es)	2011-07-04	Nuevos compuestos 578
MY149854A (en)	2013-10-31	Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
MY164864A (en)	2018-01-30	Indenone derivative and pharmaceutical composition comprising same
MX2012002369A (es)	2012-03-29	Formas de anhidrato de un derivado de piridina.
IN2012DN00569A (ru)	2015-06-12
MX2011008627A (es)	2011-09-06	Metodos de administracion de (4ar, 10ar)-1-n-propil-1,2,3,4,4a,5,1 0,10a-octahidro-benzo[g]quinolin-6,7-diol y compuestos relacionados a traves de la mucosa oral, la mucosa nasal o la piel y composiciones farmaceuticas de los mismos.
BRPI0917245B8 (pt)	2021-05-25	compostos derivados de isoquinolinona e sua composição farmacêutica