IL94754A0 - Lymphokine production and purification - Google Patents

Lymphokine production and purification

Info

Publication number: IL94754A0
Authority: IL; Israel
Prior art keywords: csf; cdna; preparing; protein; rna
Prior art date: 1984-07-06

Application number

IL94754A

Other languages

English (en)

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-07-06

Filing date

1990-06-17

Publication date

1991-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27417446&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL94754(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-06-17 Application filed by Sandoz Ag filed Critical Sandoz Ag

1990-06-17 Priority to IL94754A priority Critical patent/IL94754A0/xx

1991-04-15 Publication of IL94754A0 publication Critical patent/IL94754A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Mycology (AREA)
Immunology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Steroid Compounds (AREA)
Fats And Perfumes (AREA)
Investigating Or Analysing Biological Materials (AREA)
Debugging And Monitoring (AREA)
Detergent Compositions (AREA)
Compounds Of Unknown Constitution (AREA)

IL94754A 1984-07-06 1990-06-17 Lymphokine production and purification IL94754A0 (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IL94754A IL94754A0 (en)	1984-07-06	1990-06-17	Lymphokine production and purification

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US62834284A	1984-07-06	1984-07-06
US65244784A	1984-09-19	1984-09-19
US65274284A	1984-09-19	1984-09-19
IL75725A IL75725A (en)	1984-07-06	1985-07-04	Recombinant human gm-csf
IL94754A IL94754A0 (en)	1984-07-06	1990-06-17	Lymphokine production and purification

Publications (1)

Publication Number	Publication Date
IL94754A0 true IL94754A0 (en)	1991-04-15

Family

ID=27417446

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL75725A IL75725A (en)	1984-07-06	1985-07-04	Recombinant human gm-csf
IL94754A IL94754A0 (en)	1984-07-06	1990-06-17	Lymphokine production and purification

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
IL75725A IL75725A (en)	1984-07-06	1985-07-04	Recombinant human gm-csf

Country Status (28)

Country	Link
EP (2)	EP0337359B1 (xx)
JP (4)	JP2540509B2 (xx)
KR (1)	KR910001809B1 (xx)
AT (2)	ATE172494T1 (xx)
AU (3)	AU599572B2 (xx)
CA (2)	CA1341618C (xx)
CY (1)	CY1629A (xx)
DE (3)	DE3588199T2 (xx)
DK (2)	DK168709B1 (xx)
ES (1)	ES8701226A1 (xx)
FI (1)	FI108796B (xx)
GR (1)	GR851643B (xx)
HK (1)	HK111594A (xx)
HU (1)	HU208711B (xx)
IE (2)	IE60819B1 (xx)
IL (2)	IL75725A (xx)
LU (1)	LU88337I2 (xx)
MY (1)	MY102902A (xx)
NL (1)	NL930089I2 (xx)
NO (4)	NO179455C (xx)
NZ (2)	NZ228031A (xx)
PL (1)	PL153139B1 (xx)
PT (1)	PT80776B (xx)
SA (1)	SA94150015A (xx)
SG (1)	SG108991G (xx)
SK (1)	SK280265B6 (xx)
UA (1)	UA39161C2 (xx)
WO (1)	WO1986000639A1 (xx)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU594014B2 (en) *	1984-03-21	1990-03-01	Research Corporation Technologies, Inc.	Recombinant DNA molecules
JPS61227526A (ja) *	1984-07-25	1986-10-09	Chugai Pharmaceut Co Ltd	新規なコロニー刺激因子
ZA856108B (en) *	1984-10-29	1986-10-29	Immunex Corp	Cloning of human granulocyte-macrophage colony simulating factor gene
AU588819B2 (en) *	1984-10-29	1989-09-28	Immunex Corporation	Cloning of human granulocyte-macrophage colony stimulating factor gene
KR920003822B1 (ko) *	1984-11-20	1992-05-15	쉐링 바이오텍 코포레이션	인체 과립구 대식 세포 및 호산성 세포 성장 인자 활성을 나타내는 폴리펩티드
AU590543B2 (en) *	1985-02-05	1989-11-09	Albert Einstein College Of Medicine Of Yeshiva University	Purification of native colony stimulating factor-1
DE3681551D1 (de) *	1985-09-30	1991-10-24	Chugai Pharmaceutical Co Ltd	Menschlicher granulozyten-colony stimulierender faktor.
JPS63502795A (ja) *	1985-10-03	1988-10-20	バイオジェンインコーポレイテッド	顆粒球‐マクロファージコロニー刺激因子‐様ポリペプチド、ｄｎａ配列、組換えｄｎａ分子並びに微生物細胞中でヒト顆粒球−マクロファ−ジコロニ−刺激因子−様ポリペプチドを高収量で生産する方法
CA1295567C (en) *	1988-07-25	1992-02-11	Lawrence T. Malek	Expression system for the secretion of bioactive human granulocyte, macrophage-colony stimulating factor (gm-csf) and other heterologous proteins from streptomyces
US5298603A (en) *	1985-12-21	1994-03-29	Hoechst Aktiengesellschaft	GM-CSF protein, its derivatives, the preparation of proteins of this type, and their use
DE3545568A1 (de) *	1985-12-21	1987-07-16	Hoechst Ag	Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
IL83003A (en)	1986-07-01	1995-07-31	Genetics Inst	Osteoinductive factors
US6150328A (en)	1986-07-01	2000-11-21	Genetics Institute, Inc.	BMP products
GR871029B (en)	1986-07-14	1987-11-02	Genetics Inst	Novel osteoinductive factors
US5162111A (en) *	1986-07-30	1992-11-10	Grabstein Kenneth H	Treatment of bacterial diseases with granulocyte-macrophage colony stimulating factor
JPH01500483A (ja) *	1986-08-11	1989-02-23	シタス　コーポレイション	Ｇ‐ｃｓｆ及びそのミューテインの発現
GB8624899D0 (en) *	1986-10-17	1986-11-19	Sandoz Ltd	Monoclonal antibodies
JPH0618781B2 (ja) *	1986-10-18	1994-03-16	中外製薬株式会社	感染症治療剤
EP0276846A3 (en) *	1987-01-29	1989-07-26	Zymogenetics, Inc.	Colony-stimulating factor derivatives
JP2521094B2 (ja) *	1987-04-28	1996-07-31	アムジェン、インコーポレーテッド	ヒト顆粒球マクロファ―ジコロニ―刺激因子をコ―ドする合成ｄｎａ、そのｄｎａを含むプラスミド、およびそのｄｎａで形質転換された大腸菌
EP0383764B1 (en) *	1987-06-25	1995-04-12	Immunex Corporation	Bovine granulocyte-macrophage colony stimulating factor
KR930007430B1 (ko) *	1987-07-16	1993-08-10	쉐링 코포레이션	크로마토그래피 단계에 의한 과립구-대식세포 콜로니-자극 인자의 정제방법
US5391706A (en) *	1987-07-16	1995-02-21	Schering Plough Corporation	Purification of GM-CSF
ZA885101B (en) *	1987-07-17	1989-03-29	Schering Biotech Corp	Human granulocyte macrophage colony stimulating factor and muteins thereof
AU626530B2 (en) *	1987-07-17	1992-08-06	Schering Biotech Corporation	Human granulocyte-macrophage colony stimulating factor and muteins thereof
WO1989001038A1 (en) *	1987-07-24	1989-02-09	Cetus Corporation	PRODUCTION OF BIOLOGICALLY ACTIVE FORMS OF CSF USING A BACULOVIRUS (AcNPV)-INSECT CELL EXPRESSION SYSTEM
EP0452315A1 (en) *	1988-05-31	1991-10-23	Schering Biotech Corporation	Method of treating myeloid leukemias
AU618283B2 (en) *	1988-10-10	1991-12-19	Instituto Nazionale Per Lo Studio E La Cura Dei Tumori	The use of GM-CSF in the treatment of a patient requiring high-dose chemo- or radiotherapy for cancer
US5811523A (en)	1988-11-10	1998-09-22	Trinchieri; Giorgio	Antibodies to natural killer stimulatory factor
JPH0322973A (ja) *	1989-01-19	1991-01-31	Wan Shen-Yuan	ヒトヘパトーム細胞系によるコロニー形成促進因子（ＣＳＦｓ）の構成性産生
NZ234479A (en) *	1989-07-14	1992-03-26	Schering Corp	Antagonists of gm-csf derived from the carboxyl terminus, antibodies, hybridomas and pharmaceutical compositions containing anti-idiotypic antibodies
CA2131190C (en)	1992-02-28	2008-08-12	Peter E. Lipsky	Compositions and methods for the treatment of thermal injury
US6004807A (en) *	1992-03-30	1999-12-21	Schering Corporation	In vitro generation of human dendritic cells
US6057133A (en) *	1992-11-24	2000-05-02	G. D. Searle	Multivariant human IL-3 fusion proteins and their recombinant production
US6153183A (en)	1992-11-24	2000-11-28	G. D. Searle & Company	Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production
US5772992A (en) *	1992-11-24	1998-06-30	G.D. Searle & Co.	Compositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factors
US6403076B1 (en)	1992-11-24	2002-06-11	S. Christopher Bauer	Compositions for increasing hematopoiesis with interleukin-3 mutants
US6361977B1 (en)	1992-11-24	2002-03-26	S. Christopher Bauer	Methods of using multivariant IL-3 hematopoiesis fusion protein
US6413509B1 (en)	1992-11-24	2002-07-02	S. Christopher Bauer	Methods of ex-vivo expansion of hematopoietic cells using interleukin-3 mutant polypeptides with other hematopoietic growth factors
US7091319B1 (en)	1992-11-24	2006-08-15	Bauer S Christopher	IL-3 variant hematopoiesis fusion protein
US5738849A (en) *	1992-11-24	1998-04-14	G. D. Searle & Co.	Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US6361976B1 (en)	1992-11-24	2002-03-26	S. Christopher Bauer	Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell production
EP1770161A3 (en)	1993-05-12	2008-04-23	Genetics Institute, LLC	BMP-11 compositions
ATE210182T1 (de) *	1993-06-30	2001-12-15	Lucky Ltd	Modifizierte-granulocyte-makrophage-kolonie- stimulierender-faktor-gen und seine expression in hefe
US6291206B1 (en)	1993-09-17	2001-09-18	Genetics Institute, Inc.	BMP receptor proteins
US6027919A (en)	1993-12-07	2000-02-22	Genetics Institute, Inc.	BMP-12 and BMP-13 proteins and DNA encoding them
WO1995016035A2 (en)	1993-12-07	1995-06-15	Genetics Institute, Inc.	Bmp-12, bmp-13 and tendon-inducing compositions thereof
US5578301A (en) *	1993-12-14	1996-11-26	Sandoz Ltd.	Method for using GM-CSF to reduce the acute phase response in a patient being administered IL-6 therapy
US5599536A (en) *	1993-12-13	1997-02-04	Sandoz Ltd.	Method for suppressing the acute phase response in a patient receiving IL-6 therapy
US6165748A (en)	1997-07-11	2000-12-26	Genetics Institute, Inc.	Frazzled nucleotide sequences and expression products
US6676937B1 (en)	1998-03-09	2004-01-13	Caritas St. Elizabeth's Medical Center Of Boston Inc.	Compositions and methods for modulating vascularization
US6727224B1 (en)	1999-02-01	2004-04-27	Genetics Institute, Llc.	Methods and compositions for healing and repair of articular cartilage
DE19905501B4 (de)	1999-02-10	2005-05-19	MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie	Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
JP2002536404A (ja) *	1999-02-12	2002-10-29	ワシントンユニバーシティー	炎症性腸疾患を治療するための好中球機能の刺激
EP2286847A1 (en)	1999-10-15	2011-02-23	Genetics Institute, LLC	Formulations of hyaluronic acid for delivery of osteogenic proteins
US6869762B1 (en)	1999-12-10	2005-03-22	Whitehead Institute For Biomedical Research	Crohn's disease-related polymorphisms
WO2001042511A2 (en) *	1999-12-10	2001-06-14	Whitehead Institute For Biomedical Research	Ibd-related polymorphisms
US6689599B1 (en)	2000-10-20	2004-02-10	Genetics Institute, Llc	Aggrecanase molecules
TWI329129B (en)	2001-02-08	2010-08-21	Wyeth Corp	Modified and stabilized gdf propeptides and uses thereof
ES2305246T3 (es)	2001-06-01	2008-11-01	Wyeth	Composiciones para la administracion sistemica de secuencias que codifican proteinas oseas morfogeneticas.
TWI267378B (en)	2001-06-08	2006-12-01	Wyeth Corp	Calcium phosphate delivery vehicles for osteoinductive proteins
WO2003012038A2 (en)	2001-07-27	2003-02-13	Wyeth	Aggrecanase molecules
AU2003207795B2 (en)	2002-01-31	2009-01-08	Wyeth	Aggrecanase molecules
PL373396A1 (en)	2002-02-05	2005-08-22	Wyeth	Truncated aggrecanase molecules
EP1525307A2 (en)	2002-07-29	2005-04-27	Wyeth	Modified adamts4 molecules and method of use thereof
WO2025109150A1 (en)	2023-11-24	2025-05-30	Ludwig-Maximilians-Universität München, In Vertretung Des Freistaates Bayern	The combination of gm-csf and inhibition of ccl22-ccr4 signaling in the treatment of cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4428632A (en) *	1979-08-10	1984-01-31	Thomas & Betts Corporation	Coaxial cable transition connector
JPS6030654B2 (ja) *	1980-12-31	1985-07-17	株式会社林原生物化学研究所	ヒトコロニ−刺激因子の製造方法
US4438032A (en) *	1981-01-30	1984-03-20	The Regents Of The University Of California	Unique T-lymphocyte line and products derived therefrom
JPH0751511B2 (ja) *	1982-03-15	1995-06-05	味の素株式会社	インターロイキン２を含有してなる癌治療剤
AU594014B2 (en) *	1984-03-21	1990-03-01	Research Corporation Technologies, Inc.	Recombinant DNA molecules
ZA856108B (en) *	1984-10-29	1986-10-29	Immunex Corp	Cloning of human granulocyte-macrophage colony simulating factor gene
AU588819B2 (en) *	1984-10-29	1989-09-28	Immunex Corporation	Cloning of human granulocyte-macrophage colony stimulating factor gene

1985
- 1985-07-04 JP JP60503011A patent/JP2540509B2/ja not_active Expired - Lifetime
- 1985-07-04 DE DE3588199T patent/DE3588199T2/de not_active Expired - Lifetime
- 1985-07-04 KR KR1019860700138A patent/KR910001809B1/ko not_active Expired
- 1985-07-04 DE DE198585903275T patent/DE188479T1/de active Pending
- 1985-07-04 EP EP89106339A patent/EP0337359B1/en not_active Expired - Lifetime
- 1985-07-04 GR GR851643A patent/GR851643B/el unknown
- 1985-07-04 IE IE169585A patent/IE60819B1/en not_active IP Right Cessation
- 1985-07-04 EP EP85903275A patent/EP0188479B1/en not_active Expired - Lifetime
- 1985-07-04 NZ NZ228031A patent/NZ228031A/en unknown
- 1985-07-04 NZ NZ212645A patent/NZ212645A/xx unknown
- 1985-07-04 UA UA4027096A patent/UA39161C2/uk unknown
- 1985-07-04 WO PCT/EP1985/000326 patent/WO1986000639A1/en not_active Ceased
- 1985-07-04 ES ES544868A patent/ES8701226A1/es not_active Expired
- 1985-07-04 IE IE930961A patent/IE930961L/xx not_active IP Right Cessation
- 1985-07-04 AT AT89106339T patent/ATE172494T1/de not_active IP Right Cessation
- 1985-07-04 IL IL75725A patent/IL75725A/xx not_active IP Right Cessation
- 1985-07-04 AU AU45456/85A patent/AU599572B2/en not_active Expired
- 1985-07-04 HU HU853131A patent/HU208711B/hu unknown
- 1985-07-04 AT AT85903275T patent/ATE67244T1/de active
- 1985-07-04 DE DE8585903275T patent/DE3584089D1/de not_active Expired - Lifetime
- 1985-07-05 PT PT80776A patent/PT80776B/pt unknown
- 1985-07-05 CA CA486372A patent/CA1341618C/en active Active
- 1985-07-05 SK SK5059-85A patent/SK280265B6/sk unknown
- 1985-07-05 PL PL1985254400A patent/PL153139B1/pl unknown
1986
- 1986-01-22 FI FI860308A patent/FI108796B/fi not_active IP Right Cessation
- 1986-03-03 NO NO860775A patent/NO179455C/no not_active IP Right Cessation
- 1986-03-06 DK DK102886A patent/DK168709B1/da not_active IP Right Cessation
1987
- 1987-09-22 MY MYPI87001870A patent/MY102902A/en unknown
1989
- 1989-08-21 AU AU40090/89A patent/AU628069B2/en not_active Expired
1990
- 1990-05-14 AU AU54976/90A patent/AU644359B2/en not_active Expired
- 1990-06-17 IL IL94754A patent/IL94754A0/xx not_active IP Right Cessation
1991
- 1991-12-24 SG SG1089/91A patent/SG108991G/en unknown
1992
- 1992-07-10 CY CY1629A patent/CY1629A/xx unknown
1993
- 1993-05-21 DK DK199300594A patent/DK172679B1/da not_active IP Right Cessation
- 1993-06-22 JP JP5175978A patent/JP2594743B2/ja not_active Expired - Lifetime
- 1993-06-22 JP JP5176039A patent/JP2594744B2/ja not_active Expired - Lifetime
- 1993-06-24 NL NL930089C patent/NL930089I2/nl unknown
- 1993-06-25 LU LU88337C patent/LU88337I2/fr unknown
1994
- 1994-06-20 SA SA94150015A patent/SA94150015A/ar unknown
- 1994-09-07 NO NO19943300A patent/NO314941B1/no not_active IP Right Cessation
- 1994-10-12 HK HK111594A patent/HK111594A/en not_active IP Right Cessation
- 1994-10-19 JP JP6253317A patent/JP2594768B2/ja not_active Expired - Lifetime
1996
- 1996-01-05 CA CA000617042A patent/CA1340852C/en not_active Expired - Lifetime
- 1996-04-12 NO NO961452A patent/NO307348B1/no not_active IP Right Cessation
- 1996-12-18 NO NO1996016C patent/NO1996016I1/no unknown

Also Published As

Publication number	Publication date
EP0337359A2 (en)	1989-10-18
WO1986000639A1 (en)	1986-01-30
JP2594743B2 (ja)	1997-03-26
NZ212645A (en)	1990-02-26
NO943300L (no)	1986-03-13
PT80776A (en)	1985-08-01
EP0188479A1 (en)	1986-07-30
NO961452L (no)	1996-04-12
ES544868A0 (es)	1986-11-16
PL153139B1 (en)	1991-03-29
SG108991G (en)	1992-03-20
NO860775L (no)	1986-03-13
NL930089I2 (nl)	1994-07-01
EP0188479B1 (en)	1991-09-11
DE3584089D1 (de)	1991-10-17
IL75725A (en)	1993-02-21
JPS61502682A (ja)	1986-11-20
PL254400A1 (en)	1986-06-17
SK505985A3 (en)	1999-10-08
IE851695L (en)	1986-01-06
PT80776B (pt)	1987-09-30
SK280265B6 (sk)	1999-10-08
DK102886A (da)	1986-03-06
AU5497690A (en)	1990-09-13
IL75725A0 (en)	1985-11-29
NO943300D0 (no)	1994-09-07
GR851643B (xx)	1985-11-26
ATE67244T1 (de)	1991-09-15
JPH06199897A (ja)	1994-07-19
NO179455C (no)	1996-10-09
AU628069B2 (en)	1992-09-10
KR910001809B1 (ko)	1991-03-26
AU4545685A (en)	1986-02-10
NO961452D0 (no)	1996-04-12
NL930089I1 (nl)	1993-10-01
FI860308A7 (fi)	1986-01-22
EP0337359A3 (en)	1990-02-07
DK59493A (da)	1993-05-21
HK111594A (en)	1994-10-21
JPH07163351A (ja)	1995-06-27
DE3588199T2 (de)	1999-04-08
DK172679B1 (da)	1999-05-17
FI108796B (fi)	2002-03-28
CA1340852C (en)	1999-12-14
IE930961L (en)	1986-01-06
CY1629A (en)	1992-07-10
NO307348B1 (no)	2000-03-20
HU208711B (en)	1993-12-28
DE3588199D1 (de)	1998-11-26
MY102902A (en)	1993-03-31
CA1341618C (en)	2011-07-19
DK102886D0 (da)	1986-03-06
KR860700264A (ko)	1986-08-01
DK168709B1 (da)	1994-05-24
JP2594768B2 (ja)	1997-03-26
JPH06319557A (ja)	1994-11-22
UA39161C2 (uk)	2001-06-15
DK59493D0 (da)	1993-05-21
HK1011709A1 (en)	1999-07-16
ATE172494T1 (de)	1998-11-15
NO314941B1 (no)	2003-06-16
DE188479T1 (de)	1987-05-21
AU4009089A (en)	1989-12-07
AU644359B2 (en)	1993-12-09
FI860308A0 (fi)	1986-01-22
JP2594744B2 (ja)	1997-03-26
IE60819B1 (en)	1994-08-10
NO179455B (no)	1996-07-01
LU88337I2 (fr)	1994-05-04
SA94150015B1 (ar)	2004-09-04
SA94150015A (ar)	2005-12-03
NZ228031A (en)	1991-12-23
JP2540509B2 (ja)	1996-10-02
NO1996016I1 (no)	1996-12-18
EP0337359B1 (en)	1998-10-21
HUT38675A (en)	1986-06-30
AU599572B2 (en)	1990-07-26
ES8701226A1 (es)	1986-11-16

Publication	Publication Date	Title
AU644359B2 (en)	1993-12-09	Lymphokine production and purification
CA2203373A1 (en)	1996-05-17	Process for improved recombinant production of disulphide bond-containing polypeptides via a protein disulfide isomerase
ATE77104T1 (de)	1992-06-15	Menge und verfahren zur herstellung rekombinierter erzeugnisse in grosser ausbeute.
EP0494702A3 (en)	1992-11-19	Production of factor xiiia by gene technology
GR3006597T3 (xx)	1993-06-30

Legal Events

Date	Code	Title
1997-11-20	HC	Change of name of proprietor(s)
1999-12-22	KB	Patent renewed
2003-09-17	KB	Patent renewed
2004-07-25	NP	Permission for amending the patent specification granted (section 66, patents law 1967)
2005-11-20	EXP	Patent expired