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IL92672A0 - Retroviral protease inhibitors,their preparation and pharmaceutical compositions containing them - Google Patents

Retroviral protease inhibitors,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL92672A0
IL92672A0 IL92672A IL9267289A IL92672A0 IL 92672 A0 IL92672 A0 IL 92672A0 IL 92672 A IL92672 A IL 92672A IL 9267289 A IL9267289 A IL 9267289A IL 92672 A0 IL92672 A0 IL 92672A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
protease inhibitors
retroviral protease
Prior art date
Application number
IL92672A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IL92672A0 publication Critical patent/IL92672A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL92672A 1988-12-15 1989-12-13 Retroviral protease inhibitors,their preparation and pharmaceutical compositions containing them IL92672A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH464088 1988-12-15

Publications (1)

Publication Number Publication Date
IL92672A0 true IL92672A0 (en) 1990-09-17

Family

ID=4279903

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92672A IL92672A0 (en) 1988-12-15 1989-12-13 Retroviral protease inhibitors,their preparation and pharmaceutical compositions containing them

Country Status (15)

Country Link
EP (1) EP0374098A3 (no)
JP (1) JPH02300199A (no)
KR (1) KR900009692A (no)
AU (1) AU626361B2 (no)
CA (1) CA2005340A1 (no)
DD (1) DD290894A5 (no)
DK (1) DK633289A (no)
FI (1) FI895962A7 (no)
HU (1) HUT52525A (no)
IL (1) IL92672A0 (no)
MX (1) MX18736A (no)
NO (1) NO895026L (no)
NZ (1) NZ231750A (no)
PT (1) PT92554A (no)
ZA (1) ZA899558B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2010531A1 (en) * 1989-03-06 1990-09-06 Werner Neidhart Amino acid derivatives
AU7732691A (en) * 1990-06-01 1991-12-05 Ciba-Geigy Ag Hiv protease inhibitors and processes for their preparation
DE4126485A1 (de) * 1991-08-10 1993-02-11 Bayer Ag Trifluormethyl-haltige pseudopeptide
US5643878A (en) * 1991-09-12 1997-07-01 Ciba-Geigy Corporation 5-amino-4-hydroxyhexanoic acid derivatives
BR9306058A (pt) 1992-03-11 1997-11-18 Narhex Ltd Derivados de amina de hidrocarbonetos oxo- e hidroxi- substituidos
US6071895A (en) 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
ATE253050T1 (de) 1992-03-11 2003-11-15 Narhex Ltd Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
US5888992A (en) 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
TW217410B (no) * 1992-04-01 1993-12-11 Ciba Geigy
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
EP0626178A1 (de) * 1993-05-17 1994-11-30 Ciba-Geigy Ag Verwendung von Hemmstoffen von HIV-Aspartatproteasen zur Bekämpfung von Tumorerkrankungen
DE4332395A1 (de) * 1993-09-23 1995-04-13 Horst Dr Lindhofer Inhibitoren zur Hemmung der zymogenähnlichen Freispaltung der HIV-1 Protease
WO1998038167A1 (en) * 1997-02-26 1998-09-03 Pfizer Inc. Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of mip-1-alpha binding to its ccr1 receptor
WO2000051998A1 (en) 1999-03-02 2000-09-08 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as reversible inhibitors of cathepsin s
US6420364B1 (en) 1999-09-13 2002-07-16 Boehringer Ingelheim Pharmaceuticals, Inc. Compound useful as reversible inhibitors of cysteine proteases
AP2002002595A0 (en) * 2000-02-04 2002-09-30 Pfizer Prod Inc Heterocyclic amide derivatives.
EP1498417A1 (en) * 2000-02-04 2005-01-19 Pfizer Products Inc. Heterocyclic amide derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4727060A (en) * 1984-11-13 1988-02-23 Ciba-Geigy Corporation Novel 5-amino-4-hydroxyvaleryl derivatives
FI892036L (fi) * 1986-10-31 1989-04-28 Pfizer Polypeptider med relativt liten molekylvikt saosom renininhitorer.

Also Published As

Publication number Publication date
AU4678489A (en) 1990-06-21
ZA899558B (en) 1990-08-29
JPH02300199A (ja) 1990-12-12
NZ231750A (en) 1992-08-26
FI895962A7 (fi) 1990-06-16
FI895962A0 (fi) 1989-12-13
PT92554A (pt) 1990-06-29
KR900009692A (ko) 1990-07-05
NO895026L (no) 1990-06-18
CA2005340A1 (en) 1990-06-15
NO895026D0 (no) 1989-12-14
HUT52525A (en) 1990-07-28
DK633289D0 (da) 1989-12-14
AU626361B2 (en) 1992-07-30
DD290894A5 (de) 1991-06-13
EP0374098A3 (de) 1991-05-02
DK633289A (da) 1990-06-16
EP0374098A2 (de) 1990-06-20
MX18736A (es) 1994-02-28

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