DK633289A - Retrovirale proteasehaemmere - Google Patents

Retrovirale proteasehaemmere Download PDF

Info

Publication number: DK633289A
Authority: DK; Denmark
Prior art keywords: protease inhibitors; retroviral protease; retroviral; inhibitors; protease
Prior art date: 1988-12-15

Application number

DK633289A

Other languages

English (en)

Other versions

DK633289D0 (da

Inventor

Alexander Faessler

Ernst Hungerbuehler

Heinrich Rueeger

Peter Schneider

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-15

Filing date

1989-12-14

Publication date

1990-06-16

1989-12-14 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1989-12-14 Publication of DK633289D0 publication Critical patent/DK633289D0/da

1990-06-16 Publication of DK633289A publication Critical patent/DK633289A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Crystallography & Structural Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK633289A 1988-12-15 1989-12-14 Retrovirale proteasehaemmere DK633289A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH464088		1988-12-15

Publications (2)

Publication Number	Publication Date
DK633289D0 DK633289D0 (da)	1989-12-14
DK633289A true DK633289A (da)	1990-06-16

Family

ID=4279903

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK633289A DK633289A (da)	1988-12-15	1989-12-14	Retrovirale proteasehaemmere

Country Status (15)

Country	Link
EP (1)	EP0374098A3 (da)
JP (1)	JPH02300199A (da)
KR (1)	KR900009692A (da)
AU (1)	AU626361B2 (da)
CA (1)	CA2005340A1 (da)
DD (1)	DD290894A5 (da)
DK (1)	DK633289A (da)
FI (1)	FI895962A7 (da)
HU (1)	HUT52525A (da)
IL (1)	IL92672A0 (da)
MX (1)	MX18736A (da)
NO (1)	NO895026L (da)
NZ (1)	NZ231750A (da)
PT (1)	PT92554A (da)
ZA (1)	ZA899558B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2010531A1 (en) *	1989-03-06	1990-09-06	Werner Neidhart	Amino acid derivatives
AU7732691A (en) *	1990-06-01	1991-12-05	Ciba-Geigy Ag	Hiv protease inhibitors and processes for their preparation
DE4126485A1 (de) *	1991-08-10	1993-02-11	Bayer Ag	Trifluormethyl-haltige pseudopeptide
US5643878A (en) *	1991-09-12	1997-07-01	Ciba-Geigy Corporation	5-amino-4-hydroxyhexanoic acid derivatives
BR9306058A (pt)	1992-03-11	1997-11-18	Narhex Ltd	Derivados de amina de hidrocarbonetos oxo- e hidroxi- substituidos
US6071895A (en)	1992-03-11	2000-06-06	Narhex Limited	Polar-substituted hydrocarbons
ATE253050T1 (de)	1992-03-11	2003-11-15	Narhex Ltd	Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
US5888992A (en)	1992-03-11	1999-03-30	Narhex Limited	Polar substituted hydrocarbons
TW217410B (da) *	1992-04-01	1993-12-11	Ciba Geigy
US5559256A (en) *	1992-07-20	1996-09-24	E. R. Squibb & Sons, Inc.	Aminediol protease inhibitors
EP0626178A1 (de) *	1993-05-17	1994-11-30	Ciba-Geigy Ag	Verwendung von Hemmstoffen von HIV-Aspartatproteasen zur Bekämpfung von Tumorerkrankungen
DE4332395A1 (de) *	1993-09-23	1995-04-13	Horst Dr Lindhofer	Inhibitoren zur Hemmung der zymogenähnlichen Freispaltung der HIV-1 Protease
WO1998038167A1 (en) *	1997-02-26	1998-09-03	Pfizer Inc.	Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of mip-1-alpha binding to its ccr1 receptor
WO2000051998A1 (en)	1999-03-02	2000-09-08	Boehringer Ingelheim Pharmaceuticals, Inc.	Compounds useful as reversible inhibitors of cathepsin s
US6420364B1 (en)	1999-09-13	2002-07-16	Boehringer Ingelheim Pharmaceuticals, Inc.	Compound useful as reversible inhibitors of cysteine proteases
AP2002002595A0 (en) *	2000-02-04	2002-09-30	Pfizer Prod Inc	Heterocyclic amide derivatives.
EP1498417A1 (en) *	2000-02-04	2005-01-19	Pfizer Products Inc.	Heterocyclic amide derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4727060A (en) *	1984-11-13	1988-02-23	Ciba-Geigy Corporation	Novel 5-amino-4-hydroxyvaleryl derivatives
FI892036L (fi) *	1986-10-31	1989-04-28	Pfizer	Polypeptider med relativt liten molekylvikt saosom renininhitorer.

1989
- 1989-12-06 EP EP19890810923 patent/EP0374098A3/de not_active Withdrawn
- 1989-12-13 NZ NZ231750A patent/NZ231750A/en unknown
- 1989-12-13 IL IL92672A patent/IL92672A0/xx unknown
- 1989-12-13 FI FI895962A patent/FI895962A7/fi not_active Application Discontinuation
- 1989-12-13 DD DD89335619A patent/DD290894A5/de not_active IP Right Cessation
- 1989-12-13 CA CA002005340A patent/CA2005340A1/en not_active Abandoned
- 1989-12-13 PT PT92554A patent/PT92554A/pt not_active Application Discontinuation
- 1989-12-14 DK DK633289A patent/DK633289A/da not_active Application Discontinuation
- 1989-12-14 NO NO89895026A patent/NO895026L/no unknown
- 1989-12-14 ZA ZA899558A patent/ZA899558B/xx unknown
- 1989-12-14 KR KR1019890018523A patent/KR900009692A/ko not_active Withdrawn
- 1989-12-14 HU HU896611A patent/HUT52525A/hu unknown
- 1989-12-14 AU AU46784/89A patent/AU626361B2/en not_active Ceased
- 1989-12-15 JP JP1324111A patent/JPH02300199A/ja active Pending
- 1989-12-15 MX MX1873689A patent/MX18736A/es unknown

Also Published As

Publication number	Publication date
AU4678489A (en)	1990-06-21
ZA899558B (en)	1990-08-29
JPH02300199A (ja)	1990-12-12
NZ231750A (en)	1992-08-26
FI895962A7 (fi)	1990-06-16
FI895962A0 (fi)	1989-12-13
PT92554A (pt)	1990-06-29
IL92672A0 (en)	1990-09-17
KR900009692A (ko)	1990-07-05
NO895026L (no)	1990-06-18
CA2005340A1 (en)	1990-06-15
NO895026D0 (no)	1989-12-14
HUT52525A (en)	1990-07-28
DK633289D0 (da)	1989-12-14
AU626361B2 (en)	1992-07-30
DD290894A5 (de)	1991-06-13
EP0374098A3 (de)	1991-05-02
EP0374098A2 (de)	1990-06-20
MX18736A (es)	1994-02-28

Publication	Publication Date	Title
DK674387D0 (da)	1987-12-21	Proteaseinhibitorer
EP0415981A4 (en)	1991-10-09	Retroviral protease inhibitors
MX9100119A (es)	1992-02-28	Inhibidores de proteasa retroviral
FI894747A7 (fi)	1990-04-08	Uusia peptidaasi-inhibiittoreita
FI20012317L (fi)	2001-11-27	Retrovirusproteaasi-inhibiittoreina käyttökelpoisia hydroksietyyliaminosulfoniamideja
FI950651L (fi)	1995-02-14	Retrovirusproteaasi-inhibiittoreina käyttökelpoisia sulfonyylialkanoyyliaminohydroksietyyliaminosulfoniamideja
DE3689314D1 (de)	1994-01-05	Peptidasehemmungsmittel.
DE3785615D1 (de)	1993-06-03	Hemmungsstoffe der serin-protease.
EP0428849A3 (en)	1991-07-31	Retroviral protease inhibitors
BR8907457A (pt)	1991-04-02	Inibidores de interleucina-1
DK633289A (da)	1990-06-16	Retrovirale proteasehaemmere
FI935644A7 (fi)	1994-06-17	Retrovirusten proteaasi-inhibiittoreita
FI912240A7 (fi)	1991-05-09	Antitrombiineita
MX9100120A (es)	1992-02-28	Inhibidores de proteasas retrovirales
FI101796B1 (fi)	1998-08-31	Uusia -glukosidaasi-inhibiittoreita
FI906140A7 (fi)	1991-06-17	Retroviraalisten proteaasien inhibiittoreita
FI894092A7 (fi)	1990-03-02	Uusia peptidi-inhibiittoreita
FI890827A7 (fi)	1989-08-26	Lysyloxidas-inhibitorer.
DK174087D0 (da)	1987-04-06	Angiotensinkonverterende enzyminhibitor
DE68922014D1 (de)	1995-05-11	Protease.
DK69489D0 (da)	1989-02-15	Aspartattranscarbamylase-inhibitorer
BR8902293A (pt)	1990-01-09	Abrasivo
KR900004589U (ko)	1990-03-07	장기
MX22596A (es)	1993-11-01	Inhibidores de proteasas retrovirales.
DK658489A (da)	1989-12-22	Proteaseinhibitorer

Legal Events

Date	Code	Title	Description
1994-08-22	AHB	Application shelved due to non-payment