IL87079A0 - Tetrahydrocarbazole 1-alkanoic acids and pharmaceutical compositions containing them - Google Patents
Tetrahydrocarbazole 1-alkanoic acids and pharmaceutical compositions containing themInfo
- Publication number
- IL87079A0 IL87079A0 IL87079A IL8707988A IL87079A0 IL 87079 A0 IL87079 A0 IL 87079A0 IL 87079 A IL87079 A IL 87079A IL 8707988 A IL8707988 A IL 8707988A IL 87079 A0 IL87079 A0 IL 87079A0
- Authority
- IL
- Israel
- Prior art keywords
- tetrahydrocarbazole
- pharmaceutical compositions
- compositions containing
- alkanoic acids
- alkanoic
- Prior art date
Links
- XKLNOVWDVMWTOB-UHFFFAOYSA-N 2,3,4,9-tetrahydro-1h-carbazole Chemical compound N1C2=CC=CC=C2C2=C1CCCC2 XKLNOVWDVMWTOB-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/076,424 US4808608A (en) | 1986-01-23 | 1987-07-21 | Tetrahydrocarbazole 1-alkanoic acids, pharmaceutical compositions and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL87079A0 true IL87079A0 (en) | 1988-12-30 |
Family
ID=22131920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL87079A IL87079A0 (en) | 1987-07-21 | 1988-07-12 | Tetrahydrocarbazole 1-alkanoic acids and pharmaceutical compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4808608A (da) |
| EP (1) | EP0300676A3 (da) |
| JP (1) | JPS6470462A (da) |
| KR (1) | KR890001987A (da) |
| AU (1) | AU611454B2 (da) |
| DK (1) | DK404588A (da) |
| IL (1) | IL87079A0 (da) |
| NZ (1) | NZ225361A (da) |
| PT (1) | PT88044B (da) |
| ZA (1) | ZA885209B (da) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4940719A (en) * | 1986-03-27 | 1990-07-10 | Merck Frosst Canada, Inc. | Tetrahydrocarbazole esters, pharmaceutical compositions and use |
| GB8924392D0 (en) * | 1989-10-30 | 1989-12-20 | Bayer Ag | Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides |
| US6300361B1 (en) * | 1990-07-25 | 2001-10-09 | Novartis Ag | Stabilized pharmaceutical compositions comprising acid donors |
| US5187180A (en) * | 1990-07-26 | 1993-02-16 | Merck Frosst Canada, Inc. | (quinolin-2-ylmethoxy)heterotetrahydrocarbazoles as inhibitors of the biosynthesis of leukotrienes |
| US5221678A (en) * | 1990-07-26 | 1993-06-22 | Merck Frosst Canada, Inc. | (quinolin-2-ylmethoxy)tetrahydrocarbazoles as inhibitors of the biosynthesis of leukotrienes |
| GB9101375D0 (en) * | 1991-01-22 | 1991-03-06 | Erba Carlo Spa | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohepht(b)indole |
| US5230350A (en) * | 1991-05-29 | 1993-07-27 | Tabex Industries, Inc. | Moisture barrier for indwelling catheters and the like |
| DE4435477A1 (de) | 1994-10-04 | 1996-04-11 | Bayer Ag | Cycloalkano-indol- und -azaindol-derivate |
| US5830911A (en) * | 1996-08-14 | 1998-11-03 | American Home Products Corporation | Pyranoindole and tetrahydrocarbazole inhibitors of COX-2 |
| US20010047027A1 (en) * | 2000-04-12 | 2001-11-29 | Marc Labelle | Prostaglandin D2 receptor antagonists |
| US6410583B1 (en) * | 2000-07-25 | 2002-06-25 | Merck Frosst Canada & Co. | Cyclopentanoindoles, compositions containing such compounds and methods of treatment |
| US7217725B2 (en) * | 2000-09-14 | 2007-05-15 | Allergan, Inc. | Prostaglandin D2 antagonist |
| US7273883B2 (en) * | 2000-09-14 | 2007-09-25 | Allergan, Inc. | Prostaglandin EP4 antagonist |
| KR20040100835A (ko) | 2001-02-15 | 2004-12-02 | 킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨 | 안정된 제약및 갑상선 내분비 호르몬 구성물 및 그제조방법 |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| AR038136A1 (es) | 2002-01-24 | 2004-12-29 | Merck Frosst Canada Inc | Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento |
| DE60334015D1 (de) | 2002-10-30 | 2010-10-14 | Merck Frosst Canada Ltd | Pyridopyrrolizin- und pyridoindolizinderivate |
| WO2004063156A1 (en) * | 2003-01-08 | 2004-07-29 | Biovitrum Ab | Novel indole derivates as fabp-4 inhibitors |
| AR041089A1 (es) * | 2003-05-15 | 2005-05-04 | Merck & Co Inc | Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas |
| CN1791577A (zh) * | 2003-05-20 | 2006-06-21 | 麦克弗罗斯特加拿大有限公司 | 氟－甲基磺酰取代的环烷并吲哚和它们作为前列腺素d2拮抗剂的用途 |
| CA2527773A1 (en) * | 2003-06-12 | 2004-12-23 | Merck Frosst Canada Ltd. | Cycloalkanepyrrolopyridines as dp receptor antagonists |
| WO2005013985A1 (en) * | 2003-08-07 | 2005-02-17 | Merck Sharp & Dohme Limited | Treatment for alzheimer's disease and related conditions |
| US7019022B2 (en) * | 2003-12-15 | 2006-03-28 | Merck Frosst Canada & Co. | Substituted tetrahydrocarbazole and cyclopentanoindole derivatives |
| KR100808742B1 (ko) * | 2004-03-11 | 2008-02-29 | 액테리온 파마슈티칼 리미티드 | 테트라하이드로피리도인돌 유도체 |
| DK1833791T3 (da) | 2004-12-27 | 2011-10-24 | Actelion Pharmaceuticals Ltd | 2,3,4,9-tetrahydor-1H-carbazolderivater som CRTH2 receptorantagonister |
| WO2007047372A2 (en) * | 2005-10-14 | 2007-04-26 | The Board Of Trustees Of The University Of Illinois | Pharmacological treatments for sleep disorders (apnoe) with prostanoid receptor antagonists |
| SI2051962T1 (sl) * | 2006-08-07 | 2012-02-29 | Actelion Pharmaceuticals Ltd | Derivati (3-amino-1,2,3,4-tetrahidro-9h-karbazol-9-il)-ocetne kisline |
| WO2008097535A2 (en) * | 2007-02-08 | 2008-08-14 | Merck & Co., Inc. | Method of treating atherosclerosis, dyslipidemias and related conditions |
| ES2437323T3 (es) | 2007-02-16 | 2014-01-10 | Ono Pharmaceutical Co., Ltd. | Agente terapéutico para trastornos de la micción |
| DK2558447T3 (da) | 2010-03-22 | 2014-11-10 | Actelion Pharmaceuticals Ltd | 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazolderivater og deres anvendelse som prostaglandin d2-receptormodulatorer |
| MY165623A (en) | 2011-04-14 | 2018-04-18 | Idorsia Pharmaceuticals Ltd | 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin d2 receptor modulators |
| LT3119779T (lt) | 2014-03-17 | 2018-09-10 | Idorsia Pharmaceuticals Ltd | Azaindolo acto rūgšties dariniai ir jų panaudojimas kaip prostaglandino d2 receptoriaus moduliatorių |
| MX2016011900A (es) | 2014-03-18 | 2016-12-05 | Actelion Pharmaceuticals Ltd | Derivados de acido azaindol-acetico y su uso como moduladores del receptor de prostaglandina d2. |
| CA2993893A1 (en) | 2015-09-15 | 2017-03-23 | Idorsia Pharmaceuticals Ltd | Crystalline forms |
| CN119286871A (zh) | 2018-04-19 | 2025-01-10 | 查美特制药公司 | 合成rig-i样受体激动剂 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3896145A (en) * | 1972-07-24 | 1975-07-22 | Hoffmann La Roche | Carbazoles |
| US4009181A (en) * | 1973-01-22 | 1977-02-22 | Hoffmann-La Roche Inc. | Cyclopenta[b]indole-2-carboxylic acids and derivatives thereof |
| US4057559A (en) * | 1973-10-01 | 1977-11-08 | American Home Products Corporation | Carbazole acetic acid derivatives |
| EP0234708B1 (en) * | 1986-01-23 | 1991-02-27 | Merck Frosst Canada Inc. | Tetrahydrocarbazole 1-alkanoic acids |
-
1987
- 1987-07-21 US US07/076,424 patent/US4808608A/en not_active Expired - Fee Related
-
1988
- 1988-07-11 NZ NZ225361A patent/NZ225361A/xx unknown
- 1988-07-12 IL IL87079A patent/IL87079A0/xx unknown
- 1988-07-13 EP EP88306392A patent/EP0300676A3/en not_active Ceased
- 1988-07-19 ZA ZA885209A patent/ZA885209B/xx unknown
- 1988-07-20 KR KR1019880009051A patent/KR890001987A/ko not_active Withdrawn
- 1988-07-20 AU AU19262/88A patent/AU611454B2/en not_active Expired - Fee Related
- 1988-07-20 DK DK404588A patent/DK404588A/da not_active Application Discontinuation
- 1988-07-20 PT PT88044A patent/PT88044B/pt not_active IP Right Cessation
- 1988-07-21 JP JP63180475A patent/JPS6470462A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU1926288A (en) | 1989-01-27 |
| ZA885209B (en) | 1989-03-29 |
| JPS6470462A (en) | 1989-03-15 |
| EP0300676A2 (en) | 1989-01-25 |
| PT88044B (pt) | 1995-03-01 |
| DK404588D0 (da) | 1988-07-20 |
| PT88044A (pt) | 1989-06-30 |
| EP0300676A3 (en) | 1991-07-03 |
| KR890001987A (ko) | 1989-04-07 |
| AU611454B2 (en) | 1991-06-13 |
| US4808608A (en) | 1989-02-28 |
| NZ225361A (en) | 1991-06-25 |
| DK404588A (da) | 1989-03-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL87079A0 (en) | Tetrahydrocarbazole 1-alkanoic acids and pharmaceutical compositions containing them | |
| GB2204792B (en) | Pharmaceutical composition | |
| ZA883167B (en) | Pharmaceutical composition | |
| IL85896A (en) | Substituted di-tert.- butylphenols and pharmaceutical compositions containing them | |
| IL86086A0 (en) | Bifunctional proteins and pharmaceutical compositions containing them | |
| GB8810765D0 (en) | Pharmaceutical composition | |
| NZ226002A (en) | Peptidylheterocyclic compounds and pharmaceutical compositions | |
| GB2207922B (en) | Tripeptides and pharmaceutical compositions containing them | |
| NZ226450A (en) | Crystalline-1-carbacephalosporin and pharmaceutical compositions | |
| IL88433A0 (en) | Diarylstyrylquinoline diacids and pharmaceutical compositions containing them | |
| IL87800A0 (en) | Dioxolane-2-carboxylic acids and pharmaceutical compositions comprising them | |
| IL85969A0 (en) | Ribofuranuronic acid derivatives and pharmaceutical compositions containing them | |
| NZ224207A (en) | Substituted pyrroles and pharmaceutical compositions | |
| EG18652A (en) | Pharmaceutical compositions | |
| NZ225613A (en) | Benzazepin-2-one derivatives and pharmaceutical compositions | |
| NZ224923A (en) | 2-methoxymethyl-penem-3-carboxylic acid derivatives and pharmaceutical compositions | |
| GB8713091D0 (en) | Pharmaceutical compositions | |
| IL85524A0 (en) | Heterocyclyl-2-propyn-1-amines and pharmaceutical compositions containing same | |
| GR1002318B (el) | 8α-ακυλαμινεργολινη, περασκευη της και φαρμακευτικες συνθεσεις που την περιεχουν. | |
| IL102620A0 (en) | Benzeneethanamines and pharmaceutical compositions containing them | |
| IE872168L (en) | Pharmaceutical composition | |
| ZA881474B (en) | Pharmaceutical composition | |
| ZA883400B (en) | Pharmaceutical composition | |
| GB8725648D0 (en) | Pharmaceutical composition | |
| GB8725055D0 (en) | Pharmaceutical composition |