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IL80285A0 - The pichia pastoris argininosuccinate lyase gene and uses thereof - Google Patents

The pichia pastoris argininosuccinate lyase gene and uses thereof

Info

Publication number
IL80285A0
IL80285A0 IL80285A IL8028586A IL80285A0 IL 80285 A0 IL80285 A0 IL 80285A0 IL 80285 A IL80285 A IL 80285A IL 8028586 A IL8028586 A IL 8028586A IL 80285 A0 IL80285 A0 IL 80285A0
Authority
IL
Israel
Prior art keywords
pichia pastoris
lyase gene
argininosuccinate lyase
argininosuccinate
gene
Prior art date
Application number
IL80285A
Other languages
English (en)
Original Assignee
Phillips Petroleum Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phillips Petroleum Co filed Critical Phillips Petroleum Co
Publication of IL80285A0 publication Critical patent/IL80285A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/938Pichia

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
IL80285A 1985-10-25 1986-10-10 The pichia pastoris argininosuccinate lyase gene and uses thereof IL80285A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/791,485 US4818700A (en) 1985-10-25 1985-10-25 Pichia pastoris argininosuccinate lyase gene and uses thereof

Publications (1)

Publication Number Publication Date
IL80285A0 true IL80285A0 (en) 1987-01-30

Family

ID=25153888

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80285A IL80285A0 (en) 1985-10-25 1986-10-10 The pichia pastoris argininosuccinate lyase gene and uses thereof

Country Status (8)

Country Link
US (1) US4818700A (xx)
EP (1) EP0221455A1 (xx)
JP (1) JPS62107789A (xx)
AU (1) AU587288B2 (xx)
DK (1) DK510686A (xx)
IL (1) IL80285A0 (xx)
MX (1) MX7659E (xx)
NO (1) NO864276L (xx)

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US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
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JP2003507006A (ja) * 1999-05-20 2003-02-25 サイオス,インコーポレーテッド 血管内皮増殖因子改変体
JP2003500053A (ja) * 1999-05-20 2003-01-07 サイオス,インコーポレーテッド 血管内皮増殖因子ダイマー
US6440414B1 (en) 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
US6261820B1 (en) * 1999-10-01 2001-07-17 Amgen Inc. Fibronolytically active polypeptide
US7033776B2 (en) * 1999-12-17 2006-04-25 Amgen Inc. Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases
WO2001077366A1 (en) * 2000-04-10 2001-10-18 Cubist Pharmaceuticals, Inc. Positive selection method, compounds, host cells and uses thereof
US7625756B2 (en) 2000-06-28 2009-12-01 GycoFi, Inc. Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
US7598055B2 (en) * 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
US7863020B2 (en) * 2000-06-28 2011-01-04 Glycofi, Inc. Production of sialylated N-glycans in lower eukaryotes
US8697394B2 (en) * 2000-06-28 2014-04-15 Glycofi, Inc. Production of modified glycoproteins having multiple antennary structures
US7029872B2 (en) 2000-06-28 2006-04-18 Glycofi, Inc Methods for producing modified glycoproteins
US7449308B2 (en) 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
DK1294910T3 (da) 2000-06-30 2009-03-02 Vib Vzw Protein glykosyleringsmodifikation i Pichia Pastoris
EP2022799A2 (en) 2001-11-16 2009-02-11 Biogen Idec Inc. Polycistronic expression of antibodies
IL165717A0 (en) 2002-06-26 2006-01-15 Flanders Interuniversity Inst A strain of methylotrophic yeast for producing proteins
DE60335602D1 (de) * 2002-12-18 2011-02-17 Roche Diagnostics Gmbh Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität
ATE387494T1 (de) * 2002-12-20 2008-03-15 Hoffmann La Roche Hitzelabile desoxyribonuklease i-varianten
US7332299B2 (en) * 2003-02-20 2008-02-19 Glycofi, Inc. Endomannosidases in the modification of glycoproteins in eukaryotes
EP1460425A1 (en) * 2003-03-17 2004-09-22 Boehringer Mannheim Gmbh Deglycosylated enzymes for conjugates
ES2337684T3 (es) * 2003-12-05 2010-04-28 F. Hoffmann-La Roche Ag Carboxipeptidasa b recombinante y su purificacion.
US7588745B2 (en) * 2004-04-13 2009-09-15 Si Options, Llc Silicon-containing products
AU2006291780B2 (en) * 2005-09-14 2011-12-08 F. Hoffmann-La Roche Ag Cleavage of precursors of insulins by a variant of trypsin
EP2027271A4 (en) * 2006-05-19 2010-06-09 Glycofi Inc RECOMBINANT VECTORS
EP3078743B1 (en) 2007-09-28 2020-06-24 Portola Pharmaceuticals, Inc. Antidotes for factor xa inhibitors and methods of using the same
US8067339B2 (en) 2008-07-09 2011-11-29 Merck Sharp & Dohme Corp. Surface display of whole antibodies in eukaryotes
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BR122012024318A2 (pt) 2008-09-26 2019-07-30 Ambrx, Inc. Polipeptídeos modificados de eritropoetina animal e seus usos
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WO2011008885A1 (en) 2009-07-15 2011-01-20 Portola Pharmaceuticals, Inc. Unit dose formulation of antidotes for factor xa inhibitors and methods of using the same
AU2010307098A1 (en) 2009-10-16 2012-04-26 Merck Sharp & Dohme Corp. Method for producing proteins in Pichia pastoris that lack detectable cross binding activity to antibodies against host cell antigens
US20130011875A1 (en) 2009-10-30 2013-01-10 Merck Sharpe & Dohme Corp Methods for the production of recombinant proteins with improved secretion efficiencies
KR101930961B1 (ko) 2010-02-24 2018-12-19 머크 샤프 앤드 돔 코포레이션 피키아 파스토리스에서 생산된 치료 당단백질 상의 n-글리코실화 부위 점유를 증가시키는 방법
JP6193220B2 (ja) 2011-05-20 2017-09-06 アルダーバイオ・ホールディングズ・エルエルシー 形質転換されたピキア・パストリス(Pichiapastoris)などの微生物における抗体などのマルチサブユニットタンパク質の高純度生産
KR101978534B1 (ko) 2011-08-19 2019-08-28 앨더바이오 홀딩스 엘엘씨 변형된 미생물 이를 테면 피치아 파스토리스(pichia pastoris)에서 다수의 아단위 단백질들, 이를 테면 항체의 고역가 및 고순도 생산을 위한 다중-복사체 전략
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WO2017011275A1 (en) 2015-07-10 2017-01-19 Nersissian Aram M Factor viii protein compositions and methods of treating hemophilia a
HUE069884T2 (hu) 2015-10-09 2025-04-28 Genzyme Corp Javított flare (áramlási citometriával csillapított reporter expresszió) technológia gyors tömeges válogatáshoz
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
US11506655B2 (en) 2016-07-29 2022-11-22 Streck, Inc. Suspension composition for hematology analysis control
TWI795373B (zh) 2016-10-07 2023-03-11 美商健臻公司 用於生物製劑生產之細胞早期轉染後分離(epic)
EP3697209B1 (en) 2017-10-19 2024-07-24 Streck LLC Compositions for hemolysis and coagulation regulation and stabilization of extracellular vesicles
EP3505181B1 (en) 2017-12-28 2021-07-07 Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Preparation of enzyme replacement therapy for mucopolysaccharidosis iiid
US12421316B2 (en) 2019-02-19 2025-09-23 The Regents Of The University Of Colorado, A Body Corporate Bispecific immunotoxins targeting human CD25+CCR4+ tumors and regulatory T-cells
FI4010379T3 (fi) 2019-08-08 2025-06-26 Alexion Pharma Inc Koostumuksia ja menetelmiä tekijä XA:n ja johdannaisten valmistamiseksi
NL2031833B1 (en) 2022-05-11 2023-11-17 Univ Leiden Immunotherapeutic compositions and adjuvants
WO2024032891A1 (en) 2022-08-11 2024-02-15 Vib Vzw Glyco-engineered yeast for therapeutic protein production
WO2025196308A1 (en) 2024-03-22 2025-09-25 Vib Vzw Means and methods for displaying fc-containing proteins on cells and selection thereof

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US4617274A (en) * 1981-10-29 1986-10-14 Phillips Petroleum Company Biochemical conversions by yeast fermentation at high cell densities
US4879231A (en) * 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
US4837148A (en) * 1984-10-30 1989-06-06 Phillips Petroleum Company Autonomous replication sequences for yeast strains of the genus pichia
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast

Also Published As

Publication number Publication date
EP0221455A1 (en) 1987-05-13
NO864276D0 (no) 1986-10-24
DK510686D0 (da) 1986-10-24
DK510686A (da) 1987-04-26
NO864276L (no) 1987-04-27
JPS62107789A (ja) 1987-05-19
MX7659E (es) 1990-06-19
AU587288B2 (en) 1989-08-10
AU6388186A (en) 1987-04-30
US4818700A (en) 1989-04-04

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