[go: up one dir, main page]

DK510686D0 - Pichia pastoris-arginosuccinatlyase-gen og anvendelser deraf - Google Patents

Pichia pastoris-arginosuccinatlyase-gen og anvendelser deraf

Info

Publication number
DK510686D0
DK510686D0 DK510686A DK510686A DK510686D0 DK 510686 D0 DK510686 D0 DK 510686D0 DK 510686 A DK510686 A DK 510686A DK 510686 A DK510686 A DK 510686A DK 510686 D0 DK510686 D0 DK 510686D0
Authority
DK
Denmark
Prior art keywords
applications
pichia pastoris
lyase genes
arginosuccinate lyase
arginosuccinate
Prior art date
Application number
DK510686A
Other languages
English (en)
Other versions
DK510686A (da
Inventor
James Michael Cregg
George T Sperl
Original Assignee
Phillips Petroleum Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phillips Petroleum Co filed Critical Phillips Petroleum Co
Publication of DK510686D0 publication Critical patent/DK510686D0/da
Publication of DK510686A publication Critical patent/DK510686A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/938Pichia

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK510686A 1985-10-25 1986-10-24 Pichia pastoris-arginosuccinatlyase-gen og anvendelser deraf DK510686A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/791,485 US4818700A (en) 1985-10-25 1985-10-25 Pichia pastoris argininosuccinate lyase gene and uses thereof

Publications (2)

Publication Number Publication Date
DK510686D0 true DK510686D0 (da) 1986-10-24
DK510686A DK510686A (da) 1987-04-26

Family

ID=25153888

Family Applications (1)

Application Number Title Priority Date Filing Date
DK510686A DK510686A (da) 1985-10-25 1986-10-24 Pichia pastoris-arginosuccinatlyase-gen og anvendelser deraf

Country Status (8)

Country Link
US (1) US4818700A (da)
EP (1) EP0221455A1 (da)
JP (1) JPS62107789A (da)
AU (1) AU587288B2 (da)
DK (1) DK510686A (da)
IL (1) IL80285A0 (da)
MX (1) MX7659E (da)
NO (1) NO864276L (da)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204252A (en) * 1989-02-08 1993-04-20 Henkel Research Corporation Candida tropicalis transformation system
MY106504A (en) * 1990-07-13 1995-06-30 Transkaryotic Therapies Inc Library screening method.
WO1992013951A1 (en) * 1991-02-04 1992-08-20 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of human serum albumin in methylotrophic yeast cells
JP3811186B2 (ja) * 1994-10-18 2006-08-16 コーバス インターナショナル, インコーポレイテッド 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質
US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
CA2202351A1 (en) * 1994-10-18 1996-04-25 George Phillip Vlasuk Nematode-extracted serine protease inhibitors and anticoagulant proteins
MX9605082A (es) 1996-10-24 1998-04-30 Univ Autonoma De Nuevo Leon Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano.
JP2003507006A (ja) 1999-05-20 2003-02-25 サイオス,インコーポレーテッド 血管内皮増殖因子改変体
EP1183357A2 (en) * 1999-05-20 2002-03-06 Scios Inc. Vascular endothelial growth factor dimers
US6261820B1 (en) * 1999-10-01 2001-07-17 Amgen Inc. Fibronolytically active polypeptide
US6440414B1 (en) * 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
US7033776B2 (en) * 1999-12-17 2006-04-25 Amgen Inc. Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases
AU2001257002A1 (en) * 2000-04-10 2001-10-23 Cubist Pharmaceuticals, Inc. Positive selection method, compounds, host cells and uses thereof
US7449308B2 (en) 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US7625756B2 (en) 2000-06-28 2009-12-01 GycoFi, Inc. Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
US8697394B2 (en) * 2000-06-28 2014-04-15 Glycofi, Inc. Production of modified glycoproteins having multiple antennary structures
US7598055B2 (en) * 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
US7863020B2 (en) * 2000-06-28 2011-01-04 Glycofi, Inc. Production of sialylated N-glycans in lower eukaryotes
JP2004501642A (ja) 2000-06-28 2004-01-22 グライコフィ, インコーポレイテッド 改変された糖タンパク質を生成するための方法
MXPA02012688A (es) 2000-06-30 2004-09-10 Flanders Interuniversity Inst Modificacion de glicosilacion de proteina en pichia pastoris.
EP2022799A2 (en) 2001-11-16 2009-02-11 Biogen Idec Inc. Polycistronic expression of antibodies
IL165717A0 (en) 2002-06-26 2006-01-15 Flanders Interuniversity Inst A strain of methylotrophic yeast for producing proteins
US7118901B2 (en) * 2002-12-18 2006-10-10 Roche Diagnostics Operations, Inc. Recombinant bovine pancreatic desoxyribonuclease I with high specific activity
ATE387494T1 (de) * 2002-12-20 2008-03-15 Hoffmann La Roche Hitzelabile desoxyribonuklease i-varianten
US7332299B2 (en) * 2003-02-20 2008-02-19 Glycofi, Inc. Endomannosidases in the modification of glycoproteins in eukaryotes
EP1460425A1 (en) * 2003-03-17 2004-09-22 Boehringer Mannheim Gmbh Deglycosylated enzymes for conjugates
CA2486195C (en) * 2003-12-05 2012-03-06 Stephan Glaser Recombinantly expressed carboxypeptidase b and purification thereof
US7588745B2 (en) * 2004-04-13 2009-09-15 Si Options, Llc Silicon-containing products
MX2008003362A (es) * 2005-09-14 2008-03-25 Sanofi Aventis Deutschland Escision de precursores de insulinas mediante una variante de tripsina.
CN101535340B (zh) * 2006-05-19 2013-05-01 格利科菲公司 促红细胞生成素组合物
KR102069498B1 (ko) 2007-09-28 2020-01-23 포톨라 파마슈티컬스, 인코포레이티드 인자 Xa 저해제에 대한 안티도트 및 그것을 사용하는 방법
US8067339B2 (en) 2008-07-09 2011-11-29 Merck Sharp & Dohme Corp. Surface display of whole antibodies in eukaryotes
CA2733567A1 (en) 2008-08-12 2010-02-18 Glycofi, Inc. Improved vectors and yeast strains for protein production: ca2+ atpase overexpression
CN102232085A (zh) 2008-09-26 2011-11-02 Ambrx公司 修饰的动物促红细胞生成素多肽和其用途
PL3604510T3 (pl) 2009-03-30 2025-07-28 Alexion Pharmaceuticals, Inc. Antidota na inhibitory czynnika xa i sposoby ich stosowania
CN102625712B (zh) 2009-07-15 2017-07-25 博尔托拉制药公司 用于因子xa抑制剂的解毒剂的单位剂量制剂及其使用方法
RU2012120102A (ru) 2009-10-16 2013-12-10 Мерк Шарп И Доум Корп. Способ получения белков в pichia pastoris, у которых отсутствует поддающаяся обнаружению перекрестная связующая активность по отношению к антителам против антигенов клетки-хозяина
WO2011053541A1 (en) 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Methods for the production of recombinant proteins with improved secretion efficiencies
MX2012009802A (es) 2010-02-24 2012-09-12 Merck Sharp & Dohme Metodo para incrementar la ocupacion del sitio de n-glucosilacion en glucoproteinas terapeuticas producidas en pichia pastoris.
HRP20211873T1 (hr) 2011-05-20 2022-03-04 H. Lundbeck A/S Proizvodnja visoke čistoće proteina s više podjedinica kao što su protutijela u transformiranim mikrobima kao što je pichia pastoris
WO2013028635A1 (en) 2011-08-19 2013-02-28 Alderbio Holdings Llc Multi-copy strategy for high-titer and high-purity production of multi-subunit proteins such as a antibodies in transformed microbes such as pichia pastoris
HK1205188A1 (en) 2012-02-14 2015-12-11 Portola Pharmaceuticals, Inc. Process for making recombinant antidote to factor xa inhibitor
EP2925345B1 (en) 2012-12-03 2018-09-05 Merck Sharp & Dohme Corp. Method for making o-glycosylated carboxy terminal portion (ctp) peptide-based insulin and insulin analogues
WO2014138188A1 (en) 2013-03-07 2014-09-12 The General Hospital Corporation Human ctla4 mutants and use thereof
CA2905180C (en) 2013-03-15 2023-03-07 Alder Biopharmaceuticals, Inc. Temperature shift for high yield expression of polypeptides in yeast and other transformed cells
EP3754012A1 (en) 2013-03-15 2020-12-23 Alder Biopharmaceuticals, Inc. Antibody purification and purity monitoring
EP3024323B1 (en) 2013-07-24 2022-10-19 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
WO2017011275A1 (en) 2015-07-10 2017-01-19 Nersissian Aram M Factor viii protein compositions and methods of treating hemophilia a
AU2016335699A1 (en) 2015-10-09 2018-05-24 Genzyme Corporation Early post-transfection isolation of cells (EPIC) for biologics production
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
WO2018022991A1 (en) 2016-07-29 2018-02-01 Streck, Inc. Suspension composition for hematology analysis control
SG10202103545PA (en) 2016-10-07 2021-05-28 Genzyme Corp Early post-transfection isolation of cells (epic) for biologics production
WO2019079743A1 (en) 2017-10-19 2019-04-25 Streck, Inc. COMPOSITIONS FOR HEMOLYSIS AND REGULATION OF COAGULATION AND STABILIZATION OF EXTRACELLULAR VESICLES
EP3505181B1 (en) 2017-12-28 2021-07-07 Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Preparation of enzyme replacement therapy for mucopolysaccharidosis iiid
WO2020172344A1 (en) 2019-02-19 2020-08-27 The Regents Of The University Of Colorado, A Body Corporate Bispecific immunotoxins targeting human cd25+ccr4+ tumors and regulatory t-cells
EP4010379B1 (en) 2019-08-08 2025-04-02 Alexion Pharmaceuticals, Inc. Compositions and methods for preparing factor xa and derivatives
NL2031833B1 (en) 2022-05-11 2023-11-17 Univ Leiden Immunotherapeutic compositions and adjuvants
WO2024032891A1 (en) 2022-08-11 2024-02-15 Vib Vzw Glyco-engineered yeast for therapeutic protein production
WO2025196308A1 (en) 2024-03-22 2025-09-25 Vib Vzw Means and methods for displaying fc-containing proteins on cells and selection thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4617274A (en) * 1981-10-29 1986-10-14 Phillips Petroleum Company Biochemical conversions by yeast fermentation at high cell densities
US4837148A (en) * 1984-10-30 1989-06-06 Phillips Petroleum Company Autonomous replication sequences for yeast strains of the genus pichia
US4879231A (en) * 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast

Also Published As

Publication number Publication date
MX7659E (es) 1990-06-19
US4818700A (en) 1989-04-04
NO864276D0 (no) 1986-10-24
EP0221455A1 (en) 1987-05-13
JPS62107789A (ja) 1987-05-19
NO864276L (no) 1987-04-27
DK510686A (da) 1987-04-26
AU6388186A (en) 1987-04-30
AU587288B2 (en) 1989-08-10
IL80285A0 (en) 1987-01-30

Similar Documents

Publication Publication Date Title
DK510686D0 (da) Pichia pastoris-arginosuccinatlyase-gen og anvendelser deraf
DK480286A (da) Acrylsyreamider
ES552388A0 (es) Captador electromagnetico
NO173187C (no) Polymermateriale og anvendelser av dette
DK291186A (da) Antianafylaktiske og antibronchospastiske n-benzhydryldiazacykloalkylalkananilider
DK182686D0 (da) Elektrokemisk element
DE3680816D1 (de) Abtast- und haltestromkreis.
FR2584558B1 (fr) Element haut-parleur
BR8600709A (pt) Aco inoxidavel ferritico ultramacio
DK289085A (da) Klemelement
DK243986A (da) Polymeroplaesning
ATA370685A (de) Abschalungselement
FR2576020B1 (fr) 5-halopyridine-3-carboxamides et leurs applications
ES1000121Y (es) Sujetador de material plastico de dos piezas
DK99187D0 (da) Ionofor og ion-selektiv membran indeholdende samme
KR870000811U (ko) 울타리용 연결구
BR8600522A (pt) Composicao estabilizadora e composicao de policloreto de vinila
FR2592379B1 (fr) Pyridine-3-carboxamides et leurs applications
DK363786D0 (da) Hydroquinoliner og anvendelse deraf
KR860011599U (ko) 앵글 절곡 장치
SE8505239D0 (sv) Ferdvegsdator-program
DK489386D0 (da) Byggeelement
KR850010157U (ko) 다단식 깃대의 연결장치
BR6501325U (pt) Clip
BR6500152U (pt) Prancheta articulavel

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment