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IL55242A0 - Novel pyridine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Novel pyridine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL55242A0
IL55242A0 IL55242A IL5524278A IL55242A0 IL 55242 A0 IL55242 A0 IL 55242A0 IL 55242 A IL55242 A IL 55242A IL 5524278 A IL5524278 A IL 5524278A IL 55242 A0 IL55242 A0 IL 55242A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
pyridine derivatives
novel pyridine
Prior art date
Application number
IL55242A
Other languages
English (en)
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of IL55242A0 publication Critical patent/IL55242A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL55242A 1977-08-06 1978-07-28 Novel pyridine derivatives,their preparation and pharmaceutical compositions containing them IL55242A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3305577 1977-08-06
GB1940678 1978-05-13

Publications (1)

Publication Number Publication Date
IL55242A0 true IL55242A0 (en) 1978-09-29

Family

ID=26254035

Family Applications (1)

Application Number Title Priority Date Filing Date
IL55242A IL55242A0 (en) 1977-08-06 1978-07-28 Novel pyridine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (7)

Country Link
EP (1) EP0000816A1 (xx)
JP (1) JPS5441881A (xx)
AU (1) AU3862078A (xx)
DK (1) DK346278A (xx)
ES (4) ES472384A1 (xx)
IL (1) IL55242A0 (xx)
IT (1) IT1106623B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1160229A (en) * 1979-03-13 1984-01-10 Pieter T. Haken Pyridyliminomethylbenzene derivatives
DE3066911D1 (en) * 1979-04-21 1984-04-19 Beecham Group Plc Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions containing them
JPS5938653B2 (ja) * 1980-05-30 1984-09-18 日本ビクター株式会社 電極付き針の製作法
JPS5798143A (en) * 1980-12-05 1982-06-18 Victor Co Of Japan Ltd Base body of detection type for variation in electrostatic capacity value
DE3124673A1 (de) * 1981-06-24 1983-01-13 Bayer Ag, 5090 Leverkusen Subsituierte 2-amino-pyridinderivate, verfahren zu ihrer herstellung, ihre verwendung in arzneimitteln, sowie deren herstellung
US4552960A (en) * 1983-06-20 1985-11-12 Eli Lilly And Company Fungicidal amines
US4774251A (en) * 1984-06-18 1988-09-27 Eli Lilly And Company Method of inhibiting aromatase
US4855308A (en) * 1987-12-04 1989-08-08 Warner-Lambert Company Method of treating senile cognitive decline with N'-substituted aminopyridine adrenergic agents
US4931457B1 (en) * 1989-06-28 1993-11-16 Hoechst-Roussel Pharmaceuticals Incorporated Naphthylamino-and naphthyloxy-pyridineamin compounds useful as topical antiinflammatory agents for the treatment of skin disorders
AU630877B2 (en) * 1989-07-28 1992-11-12 Ah N. Fah Improved automatic plant watering and feeding system
FR2668770A1 (fr) * 1990-11-07 1992-05-07 Nyco Sa Esters d'acides amines heterocycliques et leurs derives, et leur application comme additifs anti-oxydants pour les huiles de graissage a temperature elevee.
GB9514160D0 (en) * 1994-07-25 1995-09-13 Zeneca Ltd Aromatic compounds
GB9420557D0 (en) * 1994-10-12 1994-11-30 Zeneca Ltd Aromatic compounds
TW502026B (en) 1995-06-20 2002-09-11 Zeneca Ltd Aromatic compounds useful as antagonists of e-type prostaglandins, processes for the preparation thereof, pharmaceutical compositions comprising the compounds, and intermediates
TW434240B (en) * 1995-06-20 2001-05-16 Zeneca Ltd Aromatic compounds, preparation thereof and pharmaceutical composition comprising same
EP0752421B1 (en) * 1995-07-07 2005-10-12 AstraZeneca AB Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists
KR100581199B1 (ko) 1998-06-19 2006-05-17 카이론 코포레이션 글리코겐 신타제 키나제 3의 억제제
DE19845406C2 (de) * 1998-10-02 2001-10-18 Aventis Pharma Gmbh Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
PL352367A1 (en) * 1999-05-17 2003-08-25 Novo Nordisk As Glucagon antagonists/inverse agonists
US6503949B1 (en) 1999-05-17 2003-01-07 Noro Nordisk A/S Glucagon antagonists/inverse agonists
RU2168501C1 (ru) * 1999-10-19 2001-06-10 Институт нефтехимии и катализа АН РБ и УНЦ РАН 2-(N-МЕТИЛ-α-ФЕНИЛ(Н-ПРОПИЛ)АМИН)-3-МЕТИЛПИРИДИН В КАЧЕСТВЕ ИНГИБИТОРА КИСЛОТНОЙ КОРРОЗИИ СТАЛИ
RU2168500C1 (ru) * 1999-10-20 2001-06-10 Институт нефтехимии и катализа АН РБ и УНЦ РАН 2-(N-МЕТИЛ-α-ФЕНИЛ(Н-БУТИЛ)АМИН)-4-МЕТИЛПИРИДИН В КАЧЕСТВЕ ИНГИБИТОРА КИСЛОТНОЙ КОРРОЗИИ СТАЛИ
EP1317266A2 (en) * 2000-08-08 2003-06-11 Ortho-McNeil Pharmaceutical, Inc. Neuroprotective 2-pyridinamine compositions and related methods
CA2602250A1 (en) * 2005-03-28 2006-10-05 Boehringer Ingelheim International Gmbh Pyridine derivatives useful as inhibitors of pkc-theta
BRPI0814403A2 (pt) 2007-07-02 2015-01-27 Hoffmann La Roche Devirados de imidazol como antagonistas de receptor ccr2

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2784138A (en) * 1953-03-07 1957-03-05 Bayer Ag Fungicidal compositions of nu-arylhydroxyarylmethylamines
DE1119274B (de) * 1954-03-19 1961-12-14 Raschig Gmbh Dr F Verfahren zur Herstellung von 2-Amino-4-alkyl-pyridinen
NL132603C (xx) * 1964-08-29
DE1670522C3 (de) * 1966-05-12 1978-08-31 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Neue Benzylaminopyridine
GB1188154A (en) * 1966-05-28 1970-04-15 Egyt Gyogyszervegyeszeti Gyar New Pyridine Derivatives and process for their preparation
US3450707A (en) * 1966-12-13 1969-06-17 Sterling Drug Inc Certain 2-anilino-pyridine derivatives
US3535328A (en) * 1967-09-01 1970-10-20 Exxon Research Engineering Co Certain substituted aminothioethoxy pyridines
FR2050940A5 (xx) * 1969-06-30 1971-04-02 Rhone Poulenc Sa
DE2141418A1 (de) * 1970-08-18 1972-03-09 Roemmers S.A. Industrial Comercial Y Financiera, Buenos Aires Anilinderivate der Nikotinsäure und ihre Salze
FR2155922A2 (en) * 1971-10-15 1973-05-25 Aries Robert Organophosphorus pesticides - stabilized by amino- or aminoalkyl-pyridines
DE2230392A1 (de) * 1972-06-22 1974-01-31 Cassella Farbwerke Mainkur Ag Substituierte pyridinverbindungen und verfahren zu ihrer herstellung
GB1405308A (en) * 1972-12-13 1975-09-10 Basf Ag Amino-pytidines as coupling components for azo dyes
FR2288798A1 (fr) * 1974-10-24 1976-05-21 Popescu Francine Bain et procede de zingage electrolytique brillant
DE2605467A1 (de) * 1976-02-12 1977-08-18 Basf Ag Pyridinverbindungen

Also Published As

Publication number Publication date
ES479933A1 (es) 1979-12-01
ES479932A1 (es) 1979-12-01
EP0000816A1 (en) 1979-02-21
IT1106623B (it) 1985-11-11
AU3862078A (en) 1980-02-07
JPS5441881A (en) 1979-04-03
IT7850601A0 (it) 1978-08-04
DK346278A (da) 1979-02-07
ES472384A1 (es) 1979-10-01
ES479931A1 (es) 1979-12-01

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