[go: up one dir, main page]

IL160148A0 - Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastasis or preventing the recurrence of malignant tumor - Google Patents

Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastasis or preventing the recurrence of malignant tumor

Info

Publication number
IL160148A0
IL160148A0 IL16014802A IL16014802A IL160148A0 IL 160148 A0 IL160148 A0 IL 160148A0 IL 16014802 A IL16014802 A IL 16014802A IL 16014802 A IL16014802 A IL 16014802A IL 160148 A0 IL160148 A0 IL 160148A0
Authority
IL
Israel
Prior art keywords
metastasis
recurrence
inhibiting
preventing
pharmaceutical compositions
Prior art date
Application number
IL16014802A
Other languages
English (en)
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of IL160148A0 publication Critical patent/IL160148A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IL16014802A 2001-08-21 2002-08-16 Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastasis or preventing the recurrence of malignant tumor IL160148A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001249717 2001-08-21
PCT/JP2002/008309 WO2003015826A1 (en) 2001-08-21 2002-08-16 Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastsis or preventing the recurrence of maligant tumor

Publications (1)

Publication Number Publication Date
IL160148A0 true IL160148A0 (en) 2004-07-25

Family

ID=19078678

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16014802A IL160148A0 (en) 2001-08-21 2002-08-16 Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastasis or preventing the recurrence of malignant tumor

Country Status (18)

Country Link
EP (1) EP1418947A1 (xx)
KR (1) KR20040027972A (xx)
CN (1) CN100372570C (xx)
AR (1) AR035137A1 (xx)
AU (1) AU2002328093B2 (xx)
BR (1) BR0212036A (xx)
CA (1) CA2457056C (xx)
HU (1) HUP0401351A3 (xx)
IL (1) IL160148A0 (xx)
MX (1) MXPA04001599A (xx)
NO (1) NO20041194L (xx)
NZ (1) NZ530947A (xx)
PL (1) PL368319A1 (xx)
RU (1) RU2275913C2 (xx)
TW (1) TWI313609B (xx)
UA (1) UA75450C2 (xx)
WO (1) WO2003015826A1 (xx)
ZA (1) ZA200400917B (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200306314A (en) * 2002-04-16 2003-11-16 Tanabe Seiyaku Co Liquid preparation comprising camptothecin derivative and pharmaceutical composition producible by lyophilizing the preparation
RU2283848C1 (ru) * 2005-06-16 2006-09-20 Институт нефтехимии и катализа РАН Республика Башкортостан Способ получения конъюгатов альгиновой кислоты
FR2914305B1 (fr) * 2007-03-29 2009-07-03 Proteins & Peptides Man Dextran fonctionnalise par des amino-acides hydrophobes.
RU2320334C1 (ru) * 2006-08-07 2008-03-27 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО НижГМА Росздрава) Средство для ингибирования роста опухоли и способ ингибирования роста опухоли в эксперименте
RU2359975C2 (ru) * 2007-04-04 2009-06-27 Институт нефтехимии и катализа РАН Способ получения модифицированных арабиногалактанов
KR20240093594A (ko) 2008-07-16 2024-06-24 칠드런'즈 메디컬 센터 코포레이션 마이크로유체 장치 내에서 역학적 운동을 일으키는 방법 및 마이크로유체 장치
AU2012262139B2 (en) * 2011-06-02 2017-02-23 Children's Medical Center Corporation Methods and uses for ex vivo tissue culture systems
PL221351B1 (pl) 2012-03-14 2016-03-31 Politechnika Warszawska Sposób otrzymywania nanocząstek polisacharydowych
US10195288B2 (en) 2012-10-11 2019-02-05 Daiichi Sankyo Company, Limited Antibody-drug conjugate
WO2014061277A1 (ja) 2012-10-19 2014-04-24 第一三共株式会社 親水性構造を含むリンカーで結合させた抗体-薬物コンジュゲート
EP3973995A1 (en) 2014-01-31 2022-03-30 Daiichi Sankyo Company, Limited Anti-her2 antibody-drug conjugate
NZ736238A (en) 2015-05-04 2022-07-01 Pfizer Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof
ES2938186T3 (es) 2015-06-29 2023-04-05 Daiichi Sankyo Co Ltd Procedimiento de fabricación selectiva de un conjugado anticuerpo-fármaco
EP3552626A4 (en) 2016-12-12 2020-06-10 Daiichi Sankyo Company, Limited ASSOCIATION OF AN ANTIBODY DRUG CONJUGATE AND AN IMMUNE CONTROL POINT INHIBITOR
BR112019012847A2 (pt) 2017-01-17 2019-12-10 Daiichi Sankyo Co Ltd anticorpo ou fragmento funcional do anticorpo, polinucleotídeo, vetor de expressão, células hospedeiras, método para produção de um anticorpo de interesse ou de um fragmento funcional do anticorpo e para produção de um conjugado de anticorpo-fármaco, conjugado de anticorpo-fármaco, composição farmacêutica, fármaco antitumoral, e, método de tratamento de um tumor.
TW202532104A (zh) 2017-05-15 2025-08-16 日商第一三共股份有限公司 抗體-藥物結合物及其用途
CN117838881A (zh) 2017-08-31 2024-04-09 第一三共株式会社 制备抗体-药物缀合物的新方法
JP7366745B2 (ja) 2017-08-31 2023-10-23 第一三共株式会社 抗体-薬物コンジュゲートの改良製造方法
PT3794042T (pt) 2018-05-18 2024-06-14 Daiichi Sankyo Co Ltd Conjugado anticorpo-fármaco anti-muc1-exatecano
AU2019311596A1 (en) 2018-07-27 2021-01-28 Daiichi Sankyo Company, Limited Protein recognizing drug moiety of antibody-drug conjugate
WO2020027100A1 (ja) 2018-07-31 2020-02-06 第一三共株式会社 抗体-薬物コンジュゲート投与による転移性脳腫瘍の治療
CN109481691A (zh) * 2018-11-20 2019-03-19 珠海天香苑生物科技发展股份有限公司 吉西他滨-羧甲基多糖共轭物、制备方法及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688931A (en) * 1993-02-26 1997-11-18 Drug Delivery System Institute, Ltd. Polysaccharide derivatives and drug carriers
SG50747A1 (en) * 1995-08-02 1998-07-20 Tanabe Seiyaku Co Comptothecin derivatives
CA2192725C (en) * 1995-12-28 2004-04-20 Kenji Tsujihara Camptothecin derivatives
EP0895784B1 (en) * 1996-04-15 2005-11-23 Asahi Kasei Kabushiki Kaisha Drug complexes comprising taxane compounds or steroids
TW527183B (en) * 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex
CN1058038C (zh) * 1996-12-31 2000-11-01 中国科学院感光化学研究所 低收缩性光固化涂层材料及其制法和用途
US6835807B1 (en) * 1998-05-22 2004-12-28 Daiichi Pharmaceuticals Co., Ltd. Drug complex and drug delivery system

Also Published As

Publication number Publication date
RU2004108141A (ru) 2005-04-20
ZA200400917B (en) 2004-08-25
BR0212036A (pt) 2004-08-17
NZ530947A (en) 2006-04-28
CN1545423A (zh) 2004-11-10
HUP0401351A3 (en) 2011-02-28
MXPA04001599A (es) 2004-07-08
AU2002328093B2 (en) 2005-05-05
CA2457056A1 (en) 2003-02-27
AR035137A1 (es) 2004-04-14
TWI313609B (en) 2009-08-21
EP1418947A1 (en) 2004-05-19
HUP0401351A2 (hu) 2004-12-28
CA2457056C (en) 2008-07-22
WO2003015826A1 (en) 2003-02-27
NO20041194L (no) 2004-03-19
RU2275913C2 (ru) 2006-05-10
UA75450C2 (en) 2006-04-17
KR20040027972A (ko) 2004-04-01
CN100372570C (zh) 2008-03-05
PL368319A1 (en) 2005-03-21

Similar Documents

Publication Publication Date Title
IL160148A0 (en) Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastasis or preventing the recurrence of malignant tumor
AU3983201A (en) Compositions and methods for the early diagnosis of ovarian cancer
IL152315A0 (en) Soluble ctla4 mutant molecules and pharmaceutical compositions containing the same
AU2001231199A1 (en) Compositions and methods for the early diagnosis of ovarian cancer
AU2002360769A1 (en) Breast cancer expression profiling
PL354540A1 (en) Drugs for the treatment of malignant tumours
IL164896A (en) Pharmaceutical compositions comprising immunoconjugates for the treatment of tumors
EP1476067A4 (en) COMPOSITIONS AND METHODS FOR CANCER
AU2002257033A1 (en) Agents and methods for the prevention of initial onset and recurrence of existing cancers
AU2002341749A1 (en) Methods and compositions for inhibiting the proliferation of prostate cancer cells
GB0110847D0 (en) Breast cancer detection
HUP0402341A3 (en) Compositions containing thiazol-2-ylamines for the treatment of cancer
AU2002239431A1 (en) Compositions and methods for the therapy and diagnosis of ovarian cancer
HUP0300772A3 (en) Medicament for the immunotherapy of malignant tumours
AU2002337943A1 (en) Novel compositions and methods for cancer
HUP0302629A3 (en) Pharmaceutical compositions comprising a combination camptothecin and a stilbene derivative for the treatment of cancer
HK1065958A (en) Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastasis or preventing the recurrence of malignant tumor
AU2001249493A1 (en) Compositions and methods for the therapy and diagnosis of ovarian cancer
AU2001271284A1 (en) Compositions and methods for the therapy and diagnosis of pancreatic cancer
AU2001296224A1 (en) Compositions and methods for the therapy and diagnosis of pancreatic cancer
GB2379444A9 (en) Assay for cancer of the prostate
AU5802200A (en) Agent for gene therapy and for the prevention of metastases, as well as for the gene therapy of tumors
IL129154A0 (en) Pharmaceutical preparation useful for the prevention of cancer metastasis
WO2003020115A9 (en) Methods and compositions for the detection of cancer
AU2001274946A1 (en) Compositions and methods for the therapy and diagnosis of ovarian cancer