IL160023A0 - Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy - Google Patents

Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy

Info

Publication number: IL160023A0
Authority: IL; Israel
Prior art keywords: therapy; preparation; pharmaceutical compositions; compositions containing; thiopene
Prior art date: 2001-07-25

Application number

IL16002302A

Other languages

English (en)

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-25

Filing date

2002-07-19

Publication date

2004-06-20

2002-07-19 Application filed by Astra Ab filed Critical Astra Ab

2004-06-20 Publication of IL160023A0 publication Critical patent/IL160023A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Cephalosporin Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL16002302A 2001-07-25 2002-07-19 Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy IL160023A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0102617A SE0102617D0 (sv)	2001-07-25	2001-07-25	Novel compounds
PCT/SE2002/001402 WO2003010163A1 (fr)	2001-07-25	2002-07-19	Nouveaux composes

Publications (1)

Publication Number	Publication Date
IL160023A0 true IL160023A0 (en)	2004-06-20

Family

ID=20284945

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL16002302A IL160023A0 (en)	2001-07-25	2002-07-19	Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy

Country Status (17)

Country	Link
US (1)	US7098240B2 (fr)
EP (1)	EP1421079B1 (fr)
JP (2)	JP2004536869A (fr)
KR (1)	KR20040018521A (fr)
CN (1)	CN1538968A (fr)
AT (1)	ATE353327T1 (fr)
BR (1)	BR0211472A (fr)
CA (1)	CA2454702A1 (fr)
DE (1)	DE60218048T2 (fr)
ES (1)	ES2280559T3 (fr)
IL (1)	IL160023A0 (fr)
MX (1)	MXPA04000755A (fr)
NO (1)	NO20040314L (fr)
NZ (1)	NZ530751A (fr)
SE (1)	SE0102617D0 (fr)
WO (1)	WO2003010163A1 (fr)
ZA (1)	ZA200400494B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
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GB0003154D0 (en) *	2000-02-12	2000-04-05	Astrazeneca Uk Ltd	Novel compounds
CZ20033368A3 (en) *	2001-06-11	2004-04-14	Shire Biochem Inc.	Thiophene derivatives as antiviral agents for flavivirus infection
SE0102616D0 (sv) *	2001-07-25	2001-07-25	Astrazeneca Ab	Novel compounds
WO2003029242A1 (fr) *	2001-10-04	2003-04-10	Smithkline Beecham Corporation	Inhibiteurs du facteur de transcription nf-$g(k)b
WO2003104218A1 (fr) *	2002-06-06	2003-12-18	Smithkline Beecham Corporation	Inhibiteurs de nf-$g(k)b
US7402608B2 (en) *	2002-12-10	2008-07-22	Virochem Pharma Inc.	Compounds and methods for the treatment or prevention of Flavivirus infections
SE0300092D0 (sv)	2003-01-15	2003-01-15	Astrazeneca Ab	Novel compounds
SE0300091D0 (sv)	2003-01-15	2003-01-15	Astrazeneca Ab	Novel compounds
US7427683B2 (en) *	2003-04-25	2008-09-23	Ortho-Mcneil Pharmaceutical, Inc.	c-fms kinase inhibitors
US7429603B2 (en) *	2003-04-25	2008-09-30	3-Dimensional Pharmaceuticals, Inc.	C-fms kinase inhibitors
US20050113566A1 (en) *	2003-04-25	2005-05-26	Player Mark R.	Inhibitors of C-FMS kinase
US7790724B2 (en)	2003-04-25	2010-09-07	Janssen Pharmaceutica N.V.	c-fms kinase inhibitors
EP1493739A1 (fr) *	2003-07-03	2005-01-05	Warner-Lambert Company LLC	Dérivés thiophényliques d'aminoacides, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
US20050085531A1 (en) *	2003-10-03	2005-04-21	Hodge Carl N.	Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
DE602004031777D1 (en) *	2004-01-05	2011-04-21	Astrazeneca Ab	Thiophenderivate als chk-1-inhibitoren
TW200616967A (en)	2004-06-24	2006-06-01	Smithkline Beecham Corp	Novel indazole carboxamides and their use
TW200626142A (en)	2004-09-21	2006-08-01	Glaxo Group Ltd	Chemical compounds
JP5030947B2 (ja)	2005-05-13	2012-09-19	ヴァイロケム・ファーマ・インコーポレーテッド	フラビウイルス感染の治療及び予防のための化合物及び方法
US8063071B2 (en)	2007-10-31	2011-11-22	GlaxoSmithKline, LLC	Chemical compounds
EA014083B1 (ru)	2005-06-30	2010-08-30	Смитклайн Бичам Корпорейшн	Новые производные индолкарбоксамида, содержащая их фармацевтическая композиция и способ лечения
CN102250074A (zh) *	2006-11-15	2011-11-23	沃泰克斯药物(加拿大)股份有限公司	用于治疗或预防黄病毒属感染的噻吩类似物
ES2397292T3 (es) *	2007-01-15	2013-03-06	Santen Pharmaceutical Co., Ltd	Nuevo derivado de indol que tiene actividad inhibidora de cinasa I B
AR065804A1 (es)	2007-03-23	2009-07-01	Smithkline Beecham Corp	Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
US11969501B2 (en)	2008-04-21	2024-04-30	Dompé Farmaceutici S.P.A.	Auris formulations for treating otic diseases and conditions
EP2278999B1 (fr)	2008-04-21	2025-01-29	Dompé farmaceutici S.p.A.	Préparations auriculaires de traitement de maladies et états otiques
JP2010043070A (ja) *	2008-07-14	2010-02-25	Santen Pharmaceut Co Ltd	カルバモイル基、ウレイド基及び置換オキシ基を有する新規インドール誘導体
CN102131774A (zh) *	2008-08-25	2011-07-20	参天制药株式会社	含有脲基、氨基羰基及可以具有取代基的二环式基团作为取代基的新型吡咯衍生物
EP2406249A1 (fr)	2009-03-10	2012-01-18	Glaxo Group Limited	Dérivés d'indole comme inhibiteurs de ikk2
GB0913345D0 (en)	2009-07-31	2009-09-16	Astrazeneca Ab	New combination 802
WO2011061527A1 (fr)	2009-11-17	2011-05-26	Astrazeneca Ab	Combinaisons qui comprennent un modulateur du récepteur glucocorticoïde, destinées au traitement de maladies respiratoires
GB201016912D0 (en)	2010-10-07	2010-11-24	Astrazeneca Ab	Novel combination
GB201021979D0 (en)	2010-12-23	2011-02-02	Astrazeneca Ab	New compound
GB201021992D0 (en)	2010-12-23	2011-02-02	Astrazeneca Ab	Compound
EP2520292A1 (fr)	2011-05-06	2012-11-07	Helmholtz-Zentrum für Infektionsforschung GmbH	Utilisation de spirangiens pour le traitement ou la prévention des troubles liés à IL-8 ou IL-6
AU2017290256A1 (en)	2016-06-29	2019-01-17	Otonomy, Inc.	Triglyceride otic formulations and uses thereof
CN107739370B (zh) *	2017-10-26	2021-03-30	中国药科大学	吡咯酮类brd4蛋白抑制剂的制备方法以及用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1468012A (en)	1973-08-09	1977-03-23	Beecham Group Ltd	2-amino-3-carboxy-thiophene derivatives
DE3529247A1 (de)	1985-05-17	1986-11-20	Bayer Ag, 5090 Leverkusen	Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung
WO1998002430A1 (fr)	1996-07-11	1998-01-22	Pfizer Pharmaceuticals Inc.	Composes de pyridylpyrrole utiles comme antagonistes de l'interleukine et du facteur tnf
PT853083E (pt) *	1997-01-06	2001-12-28	Pfizer	Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica
US6809088B2 (en) *	1997-03-24	2004-10-26	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.)	Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them
US6037340A (en)	1997-05-28	2000-03-14	Cadus Pharmaceutical Corporation	Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds
DE19744026A1 (de)	1997-10-06	1999-04-08	Hoechst Marion Roussel De Gmbh	Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln
WO1999046244A1 (fr)	1998-03-12	1999-09-16	Novo Nordisk A/S	Modulateurs de proteine tyrosine phosphatases (ptpases)
HN2000000051A (es) *	1999-05-19	2001-02-02	Pfizer Prod Inc	Derivados heterociclicos utiles como agentes anticancerosos
HUP0300382A3 (en) *	2000-03-29	2006-11-28	Cyclacel Ltd	2-substituted 4-heteroaryl-pyrimidines and their use in the treatmetn of proliferative disorders and pharmaceutical compositions containing the compounds
US6414013B1 (en)	2000-06-19	2002-07-02	Pharmacia & Upjohn S.P.A.	Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention
AU2002211663A1 (en)	2000-10-12	2002-04-22	Smith Kline Beecham Corporation	Nf-$g(k)b inhibitors

2001
- 2001-07-25 SE SE0102617A patent/SE0102617D0/xx unknown
2002
- 2002-07-19 JP JP2003515522A patent/JP2004536869A/ja not_active Withdrawn
- 2002-07-19 MX MXPA04000755A patent/MXPA04000755A/es unknown
- 2002-07-19 DE DE60218048T patent/DE60218048T2/de not_active Expired - Lifetime
- 2002-07-19 BR BR0211472-0A patent/BR0211472A/pt not_active IP Right Cessation
- 2002-07-19 CA CA002454702A patent/CA2454702A1/fr not_active Abandoned
- 2002-07-19 EP EP02756047A patent/EP1421079B1/fr not_active Expired - Lifetime
- 2002-07-19 IL IL16002302A patent/IL160023A0/xx unknown
- 2002-07-19 CN CNA028152514A patent/CN1538968A/zh active Pending
- 2002-07-19 AT AT02756047T patent/ATE353327T1/de not_active IP Right Cessation
- 2002-07-19 KR KR10-2004-7001155A patent/KR20040018521A/ko not_active Withdrawn
- 2002-07-19 US US10/484,645 patent/US7098240B2/en not_active Expired - Fee Related
- 2002-07-19 ES ES02756047T patent/ES2280559T3/es not_active Expired - Lifetime
- 2002-07-19 WO PCT/SE2002/001402 patent/WO2003010163A1/fr not_active Ceased
- 2002-07-19 NZ NZ530751A patent/NZ530751A/en unknown
2004
- 2004-01-22 ZA ZA200400494A patent/ZA200400494B/en unknown
- 2004-01-23 NO NO20040314A patent/NO20040314L/no unknown
2009
- 2009-12-22 JP JP2009291103A patent/JP2010111683A/ja active Pending

Also Published As

Publication number	Publication date
NO20040314L (no)	2004-03-25
BR0211472A (pt)	2004-11-09
ES2280559T3 (es)	2007-09-16
DE60218048T2 (de)	2007-08-09
US20040235821A1 (en)	2004-11-25
ATE353327T1 (de)	2007-02-15
CA2454702A1 (fr)	2003-02-06
NZ530751A (en)	2005-09-30
WO2003010163A1 (fr)	2003-02-06
SE0102617D0 (sv)	2001-07-25
CN1538968A (zh)	2004-10-20
MXPA04000755A (es)	2004-04-20
JP2004536869A (ja)	2004-12-09
US7098240B2 (en)	2006-08-29
EP1421079A1 (fr)	2004-05-26
KR20040018521A (ko)	2004-03-03
DE60218048D1 (de)	2007-03-22
EP1421079B1 (fr)	2007-02-07
JP2010111683A (ja)	2010-05-20
ZA200400494B (en)	2005-04-22

Publication	Publication Date	Title
IL160023A0 (en)	2004-06-20	Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy
IL160028A0 (en)	2004-06-20	Thiophene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy
IL150482A0 (en)	2002-12-01	Heteroaromatic carboxamide derivatives and their use as inhibitors of the enzyme ikk-2
MXPA02007942A (es)	2004-09-10	Derivados de pirrolopirimidinona, procesos de preparacion y uso.
HRP20040317A2 (en)	2006-06-30	1,8-naphthyridine derivatives as antidiabetics
SE0102439D0 (sv)	2001-07-05	New compounds
PL358281A1 (en)	2004-08-09	Novel compounds
ATE381537T1 (de)	2008-01-15	Formanilid-derivative als beta2-adrenorezeptor- agonisten
MXPA04004498A (es)	2004-08-11	Derivados de n-adamantilmetil e intermediarios como composiciones farmaceuticas y procesos para su preparacion.
MXPA04005099A (es)	2004-08-19	Derivados de 5-sulfanil-4h-1,2,4-triazol y su uso como medicamento.
HUP0204563A3 (en)	2004-12-28	Process for preparation of 3,3-diarylpropylamine derivatives and their intermediates and their use for preparation of pharmaceutical compositions
SE0300092D0 (sv)	2003-01-15	Novel compounds
IL157653A0 (en)	2004-03-28	Novel amides, preparation and therapeutic use as modulators of ccr-receptor activity
IL169478A0 (en)	2009-02-11	Thiophene carboxamides as inhibitors of the enzyme ikk - 2
AU2003271811A8 (en)	2004-02-02	Novel derivatives of 4,4'-dithiobis-(3-aminobutane-1-sulphonates) and compositions containing same
MXPA03011004A (es)	2004-02-27	Derivados de fenilalquiloxi-fenilo novedosos.
IL172358A0 (en)	2009-02-11	Colchicoside analogues
HUP0401895A2 (hu)	2004-12-28	Paroxetin N-formil származékai, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
MY135855A (en)	2008-07-31	"pyrrolopyrimidinone derivatives, process of preparation and use"