IL168114A - Sustained-release tramadol formulations and a tablet containing same - Google Patents

Sustained-release tramadol formulations and a tablet containing same

Info

Publication number: IL168114A
Authority: IL; Israel
Prior art keywords: tramadol; core; formulation; formulation according; coat
Prior art date: 2002-10-25

Application number

IL168114A

Other languages

English (en)

Original Assignee

Labopharm Inc

Labopharm Europe Ltd

Labopharm Barbados Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-25

Filing date

2005-04-19

Publication date

2011-05-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32179487&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL168114(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-04-19 Application filed by Labopharm Inc, Labopharm Europe Ltd, Labopharm Barbados Ltd filed Critical Labopharm Inc

2011-05-31 Publication of IL168114A publication Critical patent/IL168114A/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

IL168114A 2002-10-25 2005-04-19 Sustained-release tramadol formulations and a tablet containing same IL168114A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US28102602A	2002-10-25	2002-10-25
US51037803P	2003-10-10	2003-10-10
PCT/CA2003/001638 WO2004037222A2 (en)	2002-10-25	2003-10-27	Sustained-release tramadol formulations with 24-hour efficacy

Publications (1)

Publication Number	Publication Date
IL168114A true IL168114A (en)	2011-05-31

Family

ID=32179487

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL168114A IL168114A (en)	2002-10-25	2005-04-19	Sustained-release tramadol formulations and a tablet containing same

Country Status (11)

Country	Link
JP (1)	JP2006507277A (ru)
KR (1)	KR20050083816A (ru)
AR (1)	AR045972A1 (ru)
AU (1)	AU2003275855B2 (ru)
CA (1)	CA2503155A1 (ru)
IL (1)	IL168114A (ru)
NO (1)	NO20052479L (ru)
PT (1)	PT1594460E (ru)
RU (1)	RU2328275C2 (ru)
UA (1)	UA84277C2 (ru)
WO (1)	WO2004037222A2 (ru)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
US8487002B2 (en)	2002-10-25	2013-07-16	Paladin Labs Inc.	Controlled-release compositions
TWI319713B (en)	2002-10-25	2010-01-21		Sustained-release tramadol formulations with 24-hour efficacy
US7413749B2 (en)	2003-03-11	2008-08-19	Purdue Pharma L.P.	Titration dosing regimen for controlled release tramadol
EP1905435A3 (en) *	2003-03-11	2008-05-14	Euro-Celtique S.A.	Titration dosing regimen for controlled release tramadol
DE10361596A1 (de)	2003-12-24	2005-09-29	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102005005446A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10336400A1 (de)	2003-08-06	2005-03-24	Grünenthal GmbH	Gegen Missbrauch gesicherte Darreichungsform
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
AU2005245403B2 (en) *	2004-05-14	2012-04-19	Janssen Pharmaceutica N.V.	Carboxamido opioid compounds
DE102004032049A1 (de)	2004-07-01	2006-01-19	Grünenthal GmbH	Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
BRPI0615860B8 (pt)	2005-09-09	2021-05-25	Labopharm Barbados Ltd	composição farmacêutica de liberação prolongada monolítica sólida
PT1931346E (pt) *	2005-09-09	2012-08-14	Angelini Labopharm Llc	Composição de trazodona para administração uma vez por dia
CA2648495C (en) *	2006-04-26	2016-07-05	Alphapharm Pty Ltd	Controlled release formulations comprising uncoated discrete unit(s) and an extended release matrix
AU2009207796B2 (en)	2008-01-25	2014-03-27	Grunenthal Gmbh	Pharmaceutical dosage form
HRP20161307T1 (hr)	2008-05-09	2016-12-02	Grünenthal GmbH	Postupak za pripravu praškaste formulacije međuproizvoda i konačni kruti oblik doziranja uz korištenje koraka zgrušavanja raspršivanjem
EP2293794B1 (en)	2008-05-27	2013-05-22	The University of Melbourne	Methods of treating mammals with eustachian tube dysfunctions
MY161550A (en) *	2008-10-27	2017-04-28	Alza Corp	Extended release oral acetaminophen/tramadol dosage form
CA2765971C (en)	2009-07-22	2017-08-22	Gruenenthal Gmbh	Hot-melt extruded controlled release dosage form
PE20120631A1 (es)	2009-07-22	2012-06-06	Gruenenthal Chemie	Forma de dosificacion resistente a la manipulacion para opioides sensibles a la oxidacion
CN102821757B (zh)	2010-02-03	2016-01-20	格吕伦塔尔有限公司	通过挤出机制备粉末状药物组合物
AR082862A1 (es)	2010-09-02	2013-01-16	Gruenenthal Gmbh	Forma de dosificacion resistente a alteracion que comprende un polimero anionico
PL2611426T3 (pl)	2010-09-02	2014-09-30	Gruenenthal Gmbh	Postać dawkowania zawierająca nieorganiczne sole, odporna na zgniatanie
KR20140053159A (ko)	2011-07-29	2014-05-07	그뤼넨탈 게엠베하	즉시 약물 방출을 제공하는 탬퍼-저항성 정제
HRP20171458T1 (hr)	2011-07-29	2017-11-17	Grünenthal GmbH	Tableta otporna na mijenjanje koja pruža neposredno oslobađanje lijeka
JP6117249B2 (ja)	2012-02-28	2017-04-19	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	薬理学的に活性な化合物および陰イオン性ポリマーを含むタンパーレジスタント剤形
PT2838512T (pt)	2012-04-18	2018-11-09	Gruenenthal Gmbh	Forma farmacêutica resistente à adulteração e resistente à libertação inesperada de alta quantidade (dose-dumping)
US10064945B2 (en)	2012-05-11	2018-09-04	Gruenenthal Gmbh	Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
US9737490B2 (en)	2013-05-29	2017-08-22	Grünenthal GmbH	Tamper resistant dosage form with bimodal release profile
BR112015026549A2 (pt)	2013-05-29	2017-07-25	Gruenenthal Gmbh	forma de dosagem à prova de violação contendo uma ou mais partículas
EA032465B1 (ru)	2013-07-12	2019-05-31	Грюненталь Гмбх	Защищенная от применения не по назначению пероральная фармацевтическая лекарственная форма, содержащая этиленвинилацетатный полимер, и способ ее изготовления
HK1224189A1 (zh)	2013-11-26	2017-08-18	Grünenthal GmbH	通过低温研磨制备粉状药物组合物
EP3142646A1 (en)	2014-05-12	2017-03-22	Grünenthal GmbH	Tamper resistant immediate release capsule formulation comprising tapentadol
WO2015181059A1 (en)	2014-05-26	2015-12-03	Grünenthal GmbH	Multiparticles safeguarded against ethanolic dose-dumping
HK1246173A1 (zh)	2015-04-24	2018-09-07	Grünenthal GmbH	具有立即释放和对溶剂萃取的抗性的抗篡改剂型
WO2017042325A1 (en)	2015-09-10	2017-03-16	Grünenthal GmbH	Protecting oral overdose with abuse deterrent immediate release formulations
KR102536696B1 (ko) *	2016-05-05	2023-05-25	어퀘스티브 테라퓨틱스, 아이엔씨.	향상된 투과성을 가지는 약물학적 조성물
KR20190005199A (ko)	2016-05-05	2019-01-15	어퀘스티브 테라퓨틱스, 아이엔씨.	강화된 전달 에프네프린 조성물
US12465564B2 (en)	2021-10-25	2025-11-11	Aquestive Therapeutics, Inc.	Oral and nasal compositions and methods of treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ260408A (en) *	1993-05-10	1996-05-28	Euro Celtique Sa	Controlled release preparation comprising tramadol
DE19530575A1 (de) *	1995-08-19	1997-02-20	Gruenenthal Gmbh	Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz
DK1009387T3 (da) *	1997-07-02	2006-08-14	Euro Celtique Sa	Stabiliserede tramadolformuleringer med langvarig frigivelse
DE10015479A1 (de) *	2000-03-29	2001-10-11	Basf Ag	Feste orale Darreichungsformen mit retardierter Wirkstofffreisetzung und hoher mechanischer Stabilität
US6607748B1 (en) *	2000-06-29	2003-08-19	Vincent Lenaerts	Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
DE10108122A1 (de) *	2001-02-21	2002-10-02	Gruenenthal Gmbh	Arzneimittel auf Basis von Tramadol

2003
- 2003-10-27 AU AU2003275855A patent/AU2003275855B2/en not_active Expired
- 2003-10-27 RU RU2005115855/15A patent/RU2328275C2/ru not_active IP Right Cessation
- 2003-10-27 CA CA002503155A patent/CA2503155A1/en not_active Abandoned
- 2003-10-27 AR ARP030103926A patent/AR045972A1/es unknown
- 2003-10-27 PT PT03809237T patent/PT1594460E/pt unknown
- 2003-10-27 UA UAA200504852A patent/UA84277C2/ru unknown
- 2003-10-27 JP JP2004545655A patent/JP2006507277A/ja active Pending
- 2003-10-27 WO PCT/CA2003/001638 patent/WO2004037222A2/en not_active Ceased
- 2003-10-27 KR KR1020057007089A patent/KR20050083816A/ko not_active Ceased
2005
- 2005-04-19 IL IL168114A patent/IL168114A/en active IP Right Grant
- 2005-05-23 NO NO20052479A patent/NO20052479L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2004037222A2 (en)	2004-05-06
NO20052479D0 (no)	2005-05-23
RU2005115855A (ru)	2006-01-20
WO2004037222A3 (en)	2005-09-22
AR045972A1 (es)	2005-11-23
RU2328275C2 (ru)	2008-07-10
CA2503155A1 (en)	2004-05-06
NO20052479L (no)	2005-05-23
PT1594460E (pt)	2008-06-27
KR20050083816A (ko)	2005-08-26
AU2003275855A1 (en)	2004-05-13
JP2006507277A (ja)	2006-03-02
AU2003275855B2 (en)	2009-04-23
UA84277C2 (ru)	2008-10-10

Publication	Publication Date	Title
IL168114A (en)	2011-05-31	Sustained-release tramadol formulations and a tablet containing same
CA2489855C (en)	2010-07-20	Sustained-release tramadol formulations with 24-hour clinical efficacy
AU2003275854B9 (en)	2009-08-27	Controlled-release compositions
AU2003260336C1 (en)	2008-05-29	Sustained release formulations comprising lamotrigine
US8487002B2 (en)	2013-07-16	Controlled-release compositions
WO2003039531A1 (en)	2003-05-15	Modified release tamsulosin tablets
AU2007239057A1 (en)	2007-10-25	Low flush niacin formulation
WO2006118265A1 (ja)	2006-11-09	抗痴呆薬を含有する組成物
US20130344144A1 (en)	2013-12-26	Low flush niacin formulation
US7988998B2 (en)	2011-08-02	Sustained-release tramadol formulations with 24-hour efficacy
IL303789A (en)	2023-08-01	Oral solid preparation
CN1942175B (zh)	2010-05-26	24小时有效的曲马多缓释制剂
ZA200504216B (en)	2006-08-30	Sustained-release tramadol formulations with 24-hour efficacy
HK1101355B (en)	2011-09-16	Sustained-release tramadol formulations with 24-hour efficacy
US20090162431A1 (en)	2009-06-25	Sustained release formulations containing acetaminophen and tramadol
BRPI0315657B1 (pt)	2018-09-11	formulação de dosagem sólida, e comprimido

Legal Events

Date	Code	Title
2011-09-27	FF	Patent granted
2011-10-31	KB	Patent renewed
2013-10-31	KB	Patent renewed
2017-09-28	KB	Patent renewed
2021-10-31	KB	Patent renewed