IL164211A0 - Il-18 inhibitors and peripheral vascular diseases - Google Patents

Il-18 inhibitors and peripheral vascular diseases

Info

Publication number: IL164211A0
Authority: IL; Israel
Prior art keywords: inhibitors; peripheral vascular; vascular diseases; diseases; peripheral
Prior art date: 2002-03-22

Application number

IL16421103A

Other languages

English (en)

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-22

Filing date

2003-03-13

Publication date

2005-12-18

2003-03-13 Application filed by Applied Research Systems filed Critical Applied Research Systems

2005-12-18 Publication of IL164211A0 publication Critical patent/IL164211A0/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Marine Sciences & Fisheries (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Neurology (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Microbiology (AREA)
Mycology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

IL16421103A 2002-03-22 2003-03-13 Il-18 inhibitors and peripheral vascular diseases IL164211A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP02100290		2002-03-22
PCT/EP2003/050061 WO2003080104A2 (en)	2002-03-22	2003-03-13	Use of il-18 inhibitors for the treatment and/or prevention of peripheral vascular diseases

Publications (1)

Publication Number	Publication Date
IL164211A0 true IL164211A0 (en)	2005-12-18

Family

ID=28051827

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL16421103A IL164211A0 (en)	2002-03-22	2003-03-13	Il-18 inhibitors and peripheral vascular diseases
IL164211A IL164211A (en)	2002-03-22	2004-09-22	Il-18 inhibitors in peripheral vascular diseases of the extremities

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL164211A IL164211A (en)	2002-03-22	2004-09-22	Il-18 inhibitors in peripheral vascular diseases of the extremities

Country Status (27)

Country	Link
US (2)	US9592267B2 (es)
EP (1)	EP1487541B1 (es)
JP (1)	JP4885424B2 (es)
KR (1)	KR20050004809A (es)
CN (1)	CN100540058C (es)
AR (1)	AR039103A1 (es)
AT (1)	ATE414556T1 (es)
AU (1)	AU2003219162B2 (es)
BR (1)	BRPI0308663B8 (es)
CA (1)	CA2478855C (es)
CY (1)	CY1108748T1 (es)
DE (1)	DE60324777D1 (es)
DK (1)	DK1487541T3 (es)
EA (1)	EA008495B1 (es)
ES (1)	ES2314191T3 (es)
HR (1)	HRP20040758B1 (es)
IL (2)	IL164211A0 (es)
ME (1)	ME00548B (es)
MX (1)	MXPA04009135A (es)
NO (1)	NO336226B1 (es)
PL (1)	PL207303B1 (es)
PT (1)	PT1487541E (es)
RS (1)	RS51755B (es)
SI (1)	SI1487541T1 (es)
UA (1)	UA80275C2 (es)
WO (1)	WO2003080104A2 (es)
ZA (1)	ZA200407022B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7914814B2 (en)	1997-09-17	2011-03-29	Strategic Science & Technologies, Llc	Topical delivery of arginine of cause beneficial effects
CN102206277A (zh) *	2000-02-10	2011-10-05	雅培制药有限公司	结合人白介素-18的抗体及制备和使用方法
PL207303B1 (pl)	2002-03-22	2010-11-30	Inst Nat Sante Rech Med	Zastosowanie inhibitora IL-18 do leczenia i/lub zapobiegania chorobom naczyń obwodowych i zastosowanie wektorów ekspresyjnych
US7968684B2 (en)	2003-11-12	2011-06-28	Abbott Laboratories	IL-18 binding proteins
IL159670A0 (en) *	2003-12-31	2004-06-01	Yeda Res & Dev	Use of il-18 binding protein in inflammations
JP2007532697A (ja) *	2004-04-19	2007-11-15	ストラテジックサイエンスアンドテクノロジーズ，エルエルシー	局所的血流増大の有益な効果
US9226909B2 (en)	2004-04-19	2016-01-05	Strategic Science & Technologies, Llc	Beneficial effects of increasing local blood flow
PL1885753T3 (pl)	2005-06-03	2011-12-30	Ares Trading Sa	Wytwarzanie rekombinowanego białka wiążącego IL-18
ATE529433T1 (de)	2005-06-10	2011-11-15	Ares Trading Sa	Verfahren zur reinigung eines il-18-bindenden proteins
US10106587B2 (en)	2008-02-27	2018-10-23	Biomet Biologics, Llc	Methods and compositions for delivering interleukin-1 receptor antagonist
US8753690B2 (en)	2008-02-27	2014-06-17	Biomet Biologics, Llc	Methods and compositions for delivering interleukin-1 receptor antagonist
US9072659B2 (en)	2009-06-24	2015-07-07	Strategic Science & Technologies, Llc	Topical composition containing naproxen
US11684624B2 (en)	2009-06-24	2023-06-27	Strategic Science & Technologies, Llc	Treatment of erectile dysfunction and other indications
US12138268B2 (en)	2009-06-24	2024-11-12	Strategic Science & Technologies, Llc	Treatment of erectile dysfunction and other indications
ES2607476T3 (es)	2009-06-24	2017-03-31	Strategic Science & Technologies, Llc	Composición tópica que contiene ibuprofeno
US9763875B2 (en)	2009-08-27	2017-09-19	Biomet Biologics, Llc	Implantable device for production of interleukin-1 receptor antagonist
JP2013506686A (ja)	2009-09-30	2013-02-28	プレジデントアンドフェロウズオブハーバードカレッジ	オートファジー阻害遺伝子産物の変調によりオートファジーを変調する方法
EP2609117B1 (en)	2010-08-25	2015-09-16	F.Hoffmann-La Roche Ag	Antibodies against il-18r1 and uses thereof
JP2014501283A (ja)	2010-12-29	2014-01-20	ストラテジックサイエンスアンドテクノロジーズ，エルエルシー	アレルギーおよび他の適応症の処置のためのシステムおよび方法
JP2014504592A (ja)	2010-12-29	2014-02-24	ストラテジックサイエンスアンドテクノロジーズ，エルエルシー	勃起不全および他の適応症の処置
JOP20200308A1 (ar)	2012-09-07	2017-06-16	Novartis Ag	جزيئات إرتباط il-18
US9878011B2 (en)	2013-03-15	2018-01-30	Biomet Biologics, Llc	Treatment of inflammatory respiratory disease using biological solutions
US9895418B2 (en) *	2013-03-15	2018-02-20	Biomet Biologics, Llc	Treatment of peripheral vascular disease using protein solutions
US10143725B2 (en)	2013-03-15	2018-12-04	Biomet Biologics, Llc	Treatment of pain using protein solutions
US9950035B2 (en)	2013-03-15	2018-04-24	Biomet Biologics, Llc	Methods and non-immunogenic compositions for treating inflammatory disorders
US9758806B2 (en)	2013-03-15	2017-09-12	Biomet Biologics, Llc	Acellular compositions for treating inflammatory disorders
US20140271589A1 (en)	2013-03-15	2014-09-18	Biomet Biologics, Llc	Treatment of collagen defects using protein solutions
US10208095B2 (en)	2013-03-15	2019-02-19	Biomet Manufacturing, Llc	Methods for making cytokine compositions from tissues using non-centrifugal methods
US9833474B2 (en)	2013-11-26	2017-12-05	Biomet Biologies, LLC	Methods of mediating macrophage phenotypes
US10441635B2 (en)	2014-11-10	2019-10-15	Biomet Biologics, Llc	Methods of treating pain using protein solutions
CA2972689A1 (en)	2015-03-05	2016-09-09	Ab2 Bio Sa	Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases
US9763800B2 (en)	2015-03-18	2017-09-19	Biomet C. V.	Implant configured for hammertoe and small bone fixation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5877197A (en) *	1996-12-16	1999-03-02	Karanewsky; Donald S.	C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases
IL121860A0 (en) *	1997-08-14	1998-02-22	Yeda Res & Dev	Interleukin-18 binding proteins their preparation and use
CA2276216A1 (en) *	1998-06-24	1999-12-24	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	An artificial peptide capable of neutralizing the biological activity of interleukin-18
CA2340579A1 (en) *	1998-09-01	2000-03-09	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Interleukin 18-binding protein
DE60041432D1 (de) *	1999-11-16	2009-03-12	Hayashibara Biochem Lab	Antikörper spezifisch für den Interleukin-18 Vorläufer
EA007014B1 (ru)	2000-05-05	2006-06-30	Апплайд Резеч Системз Арс Холдинг Н.В.	Применение il-18 в качестве диагностического маркера
PE20011350A1 (es)	2000-05-19	2002-01-15	Vertex Pharma	PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
AU2002224417A1 (en) *	2000-10-18	2002-04-29	Immunex Corporation	Methods for treating il-18 mediated disorders
PL207303B1 (pl)	2002-03-22	2010-11-30	Inst Nat Sante Rech Med	Zastosowanie inhibitora IL-18 do leczenia i/lub zapobiegania chorobom naczyń obwodowych i zastosowanie wektorów ekspresyjnych

2003
- 2003-03-13 PL PL372398A patent/PL207303B1/pl unknown
- 2003-03-13 SI SI200331457T patent/SI1487541T1/sl unknown
- 2003-03-13 PT PT03714958T patent/PT1487541E/pt unknown
- 2003-03-13 DK DK03714958T patent/DK1487541T3/da active
- 2003-03-13 DE DE60324777T patent/DE60324777D1/de not_active Expired - Lifetime
- 2003-03-13 AT AT03714958T patent/ATE414556T1/de active
- 2003-03-13 UA UA20041008590A patent/UA80275C2/uk unknown
- 2003-03-13 AU AU2003219162A patent/AU2003219162B2/en not_active Expired
- 2003-03-13 WO PCT/EP2003/050061 patent/WO2003080104A2/en not_active Ceased
- 2003-03-13 BR BRPI0308663A patent/BRPI0308663B8/pt not_active IP Right Cessation
- 2003-03-13 IL IL16421103A patent/IL164211A0/xx unknown
- 2003-03-13 EP EP03714958A patent/EP1487541B1/en not_active Expired - Lifetime
- 2003-03-13 HR HRP20040758AA patent/HRP20040758B1/hr not_active IP Right Cessation
- 2003-03-13 ES ES03714958T patent/ES2314191T3/es not_active Expired - Lifetime
- 2003-03-13 CA CA2478855A patent/CA2478855C/en not_active Expired - Lifetime
- 2003-03-13 RS YU81504A patent/RS51755B/sr unknown
- 2003-03-13 KR KR10-2004-7014401A patent/KR20050004809A/ko not_active Ceased
- 2003-03-13 EA EA200401240A patent/EA008495B1/ru not_active IP Right Cessation
- 2003-03-13 CN CNB038116510A patent/CN100540058C/zh not_active Expired - Lifetime
- 2003-03-13 US US10/508,574 patent/US9592267B2/en not_active Expired - Lifetime
- 2003-03-13 ME MEP-2008-679A patent/ME00548B/me unknown
- 2003-03-13 JP JP2003577930A patent/JP4885424B2/ja not_active Expired - Lifetime
- 2003-03-13 MX MXPA04009135A patent/MXPA04009135A/es active IP Right Grant
- 2003-03-21 AR ARP030101000A patent/AR039103A1/es not_active Application Discontinuation
2004
- 2004-09-02 ZA ZA200407022A patent/ZA200407022B/en unknown
- 2004-09-22 IL IL164211A patent/IL164211A/en active IP Right Grant
- 2004-10-20 NO NO20044459A patent/NO336226B1/no not_active IP Right Cessation
2009
- 2009-02-05 CY CY20091100132T patent/CY1108748T1/el unknown
2010
- 2010-06-01 US US12/791,052 patent/US9566313B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1487541B1 (en)	2008-11-19
AR039103A1 (es)	2005-02-09
ES2314191T3 (es)	2009-03-16
NO336226B1 (no)	2015-06-22
HK1075422A1 (zh)	2005-12-16
CN1655845A (zh)	2005-08-17
IL164211A (en)	2011-07-31
JP4885424B2 (ja)	2012-02-29
UA80275C2 (en)	2007-09-10
PT1487541E (pt)	2008-12-10
BRPI0308663B8 (pt)	2021-05-25
EA200401240A1 (ru)	2005-02-24
JP2005520852A (ja)	2005-07-14
WO2003080104A3 (en)	2004-03-04
AU2003219162B2 (en)	2008-01-03
CY1108748T1 (el)	2014-04-09
DK1487541T3 (da)	2009-01-19
SI1487541T1 (sl)	2009-02-28
ZA200407022B (en)	2006-06-28
RS81504A (sr)	2006-12-15
US20100291028A1 (en)	2010-11-18
PL207303B1 (pl)	2010-11-30
US20060233799A1 (en)	2006-10-19
DE60324777D1 (de)	2009-01-02
RS51755B (sr)	2011-12-31
ME00548B (me)	2011-10-10
EA008495B1 (ru)	2007-06-29
BRPI0308663B1 (pt)	2019-07-16
ATE414556T1 (de)	2008-12-15
CA2478855A1 (en)	2003-10-02
WO2003080104A2 (en)	2003-10-02
PL372398A1 (en)	2005-07-25
CN100540058C (zh)	2009-09-16
HRP20040758B1 (hr)	2012-10-31
HRP20040758A2 (en)	2005-02-28
BR0308663A (pt)	2005-01-25
US9566313B2 (en)	2017-02-14
AU2003219162A1 (en)	2003-10-08
EP1487541A2 (en)	2004-12-22
MXPA04009135A (es)	2004-12-07
NO20044459L (no)	2004-10-20
US9592267B2 (en)	2017-03-14
CA2478855C (en)	2013-12-17
KR20050004809A (ko)	2005-01-12

Publication	Publication Date	Title
IL164211A0 (en)	2005-12-18	Il-18 inhibitors and peripheral vascular diseases
HRP20041029A2 (en)	2004-12-31	Therapeutic use of selcetive pde10 inhibitors
PL374598A1 (en)	2005-10-31	Caspase inhibitors and uses thereof
PL375052A1 (en)	2005-11-14	Pharmaceutical pig and method of use
EP1511488A4 (en)	2008-11-19	HUMAN INHIBITORS OF ADAM 10
IL201111A0 (en)	2010-05-17	Ester compound and medical use thereof
AU2003303128A8 (en)	2004-08-13	Inhibitors and methods of use thereof
ZA200509700B (en)	2007-03-28	Caspase inhibitors and uses thereof
EP1551384A4 (en)	2008-04-09	R-NSAID ESTERS AND ITS USE
EP1572741A4 (en)	2006-09-27	DIAGNOSTIC AND THERAPEUTIC AGENTS
IL157024A0 (en)	2004-02-08	Il-18 inhibitors in heart disease
GB0212405D0 (en)	2002-07-10	Composition and its therapeutic use
GB0219660D0 (en)	2002-10-02	Therapeutic use
AU2003206945A1 (en)	2003-09-09	Use of proteinase inhibitors in the treatment of autoimmune diseases
GB0207410D0 (en)	2002-05-08	Compounds and their therapeutic use
AU2003251513A8 (en)	2003-12-31	Rsk inhibitors and therapeutic uses thereof
PL397022A1 (pl)	2012-03-26	Środek leczniczy
EP1603535A4 (en)	2008-10-15	AROMATASE HEMMER DIAGNOSIS AND THERAPY
EP1569928A4 (en)	2008-12-10	THERAPEUTIC COMPOUNDS AND METHOD
GB0207409D0 (en)	2002-05-08	Benzofuran-2H-3-one compounds and their therapeutic use
GB0215773D0 (en)	2002-08-14	Compunds and their therapeutic use
GB0205826D0 (en)	2002-04-24	Therapeutic compositions and methods
AU2003238948A8 (en)	2003-12-22	Caspase-1 inhibitors and methods for their use
AU2003235665A8 (en)	2003-07-30	Diagnostic and therapeutic uses of topors
ZA200500776B (en)	2006-09-27	Caspase inhibitors and uses thereof