IL152337A0 - A pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds - Google Patents

A pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds

Info

Publication number: IL152337A0
Authority: IL; Israel
Prior art keywords: pyridine; transformation; pharmaceutically effective; oxide; oxide derivative
Prior art date: 2000-04-18

Application number

IL15233701A

Other languages

English (en)

Original Assignee

Biorex Kutato Fejlesztoe Kft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-04-18

Filing date

2001-04-17

Publication date

2003-05-29

2001-04-17 Application filed by Biorex Kutato Fejlesztoe Kft filed Critical Biorex Kutato Fejlesztoe Kft

2003-05-29 Publication of IL152337A0 publication Critical patent/IL152337A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL15233701A 2000-04-18 2001-04-17 A pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds IL152337A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU0001583A HUP0001583A2 (hu)	2000-04-18	2000-04-18	Egy piridin-1-oxid-származék és eljárás annak átalakítására gyógyászati hatású vegyületekké
PCT/HU2001/000046 WO2001079174A1 (en)	2000-04-18	2001-04-17	A pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds

Publications (1)

Publication Number	Publication Date
IL152337A0 true IL152337A0 (en)	2003-05-29

Family

ID=90001563

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15233701A IL152337A0 (en)	2000-04-18	2001-04-17	A pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds
IL152337A IL152337A (en)	2000-04-18	2002-10-17	History of Pyridine-1-Oxide and the Process for Its Conversion to Pharmaceutically Effective Compounds

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL152337A IL152337A (en)	2000-04-18	2002-10-17	History of Pyridine-1-Oxide and the Process for Its Conversion to Pharmaceutically Effective Compounds

Country Status (31)

Country	Link
US (1)	US7126002B2 (es)
EP (1)	EP1274685B1 (es)
JP (1)	JP5066638B2 (es)
KR (1)	KR100742482B1 (es)
CN (1)	CN1216868C (es)
AT (1)	ATE332894T1 (es)
AU (2)	AU2001254997B2 (es)
BG (1)	BG65889B1 (es)
BR (1)	BRPI0110184B8 (es)
CA (1)	CA2406266C (es)
CY (1)	CY1107473T1 (es)
CZ (1)	CZ301576B6 (es)
DE (1)	DE60121431T2 (es)
DK (1)	DK1274685T3 (es)
EE (1)	EE05085B1 (es)
ES (1)	ES2267758T3 (es)
HR (1)	HRP20020825A2 (es)
HU (1)	HUP0001583A2 (es)
IL (2)	IL152337A0 (es)
MX (1)	MXPA02010320A (es)
NO (1)	NO323535B1 (es)
NZ (1)	NZ522017A (es)
PL (1)	PL359826A1 (es)
PT (1)	PT1274685E (es)
RS (1)	RS51003B (es)
RU (1)	RU2281282C2 (es)
SI (1)	SI1274685T1 (es)
SK (1)	SK287606B6 (es)
UA (1)	UA75353C2 (es)
WO (1)	WO2001079174A1 (es)
ZA (1)	ZA200208460B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP9900475D0 (en) *	1999-02-26	1999-04-28	Biorex Kutato Fejlesztoe Kft	O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component
HU0103939D0 (en) *	2001-09-27	2001-11-28	Biorex Kutato Fejlesztoe Kft	Pharmaceutical composition containing methformin and n-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride
MXPA04006716A (es) *	2002-01-11	2004-11-10	Biorex Kutato Es Rejleszt Rt	Derivados de carboxamidina y su uso en el tratamiento de enfermedades vasculares.
HUP0303584A3 (en)	2003-10-30	2009-12-28	Cytrx Corp	Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases
TW200831479A (en) *	2006-09-26	2008-08-01	Cytrx Corp	Pharmaceutical compositions and methods for treating diseases
DK2318032T3 (da)	2008-06-26	2012-06-11	Orphazyme Aps	Anvendelse af Hsp70 som regulator af enzymatisk aktivitet
US9662375B2 (en)	2010-11-30	2017-05-30	Orphazyme Aps	Methods for increasing intracellular activity of Hsp70
HUP1100534A2 (en)	2011-09-26	2013-04-29	Balazs Dr Hazay	Pharmaceutical composition for the treatment of muscle atrophy
HUP1100535A2 (en)	2011-09-26	2013-04-29	Bracelia Invest Ltd	Pharmaceutical composition for enhancement of stem cell treatment
CN107106494B (zh)	2014-09-15	2021-12-21	奥菲泽米有限公司	阿瑞洛莫制剂
US10898476B2 (en)	2016-04-13	2021-01-26	Orphazyme A/S	Heat shock proteins and cholesterol homeostasis
HRP20210047T1 (hr)	2016-04-29	2021-04-16	Orphazyme A/S, c/o COBIS A/S	Arimoclomol za liječenje poremećaja povezanih s glukocerebrozidazom
BR112020005732A2 (pt)	2017-09-22	2020-10-27	The University Of Adelaide	métodos e produtos para melhorar a qualidade de espermatozoides
HUP1800298A1 (hu)	2018-08-30	2020-05-28	N Gene Res Laboratories Inc	Gyógyszerkombináció béta-receptor blokkolók hatásának módosítására és a mellékhatások csökkentésére
IL299250A (en)	2020-06-24	2023-02-01	Kempharm Denmark As	Arimoclomol for the treatment of Gaucher disease
KR20230128462A (ko) *	2020-11-19	2023-09-05	제브라 덴마크 에이/에스	아리모클로몰 시트레이트 및 이의 중간체를 제조하기 위한 공정
CN116783164A (zh) *	2020-11-19	2023-09-19	泽维拉丹麦股份有限公司	制备柠檬酸阿瑞洛莫及其中间体的方法
MX2023007551A (es)	2020-12-24	2023-09-04	Zevra Denmark As	Arimoclomol para el tratamiento de la enfermedad de niemann pick, tipo c, en pacientes con mutaciones de sentido erroneo de tipo reticulo endoplasmatico (er).
AU2023454616A1 (en)	2023-07-10	2026-01-22	N-Gene Research Laboratories, Inc.	Increasing telomere length and/or suppressing telomere shortening

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU207988B (en) *	1988-10-20	1993-07-28	Biorex Kutato Fejlesztoe Kft	Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components
HU9502843D0 (en)	1995-09-29	1995-11-28	Livigene Ltd	Pharmaceutical composition
HU222994B1 (hu) *	1995-11-02	2004-01-28	BIOREX Kutató és Fejlesztő Rt.	Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására
HUP9900475D0 (en) *	1999-02-26	1999-04-28	Biorex Kutato Fejlesztoe Kft	O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component

2000
- 2000-04-18 HU HU0001583A patent/HUP0001583A2/hu unknown
2001
- 2001-04-17 EP EP01928133A patent/EP1274685B1/en not_active Expired - Lifetime
- 2001-04-17 NZ NZ522017A patent/NZ522017A/en unknown
- 2001-04-17 DE DE60121431T patent/DE60121431T2/de not_active Expired - Lifetime
- 2001-04-17 KR KR1020027014047A patent/KR100742482B1/ko not_active Expired - Fee Related
- 2001-04-17 RS YUP-783/02A patent/RS51003B/sr unknown
- 2001-04-17 AU AU2001254997A patent/AU2001254997B2/en not_active Expired
- 2001-04-17 MX MXPA02010320A patent/MXPA02010320A/es active IP Right Grant
- 2001-04-17 WO PCT/HU2001/000046 patent/WO2001079174A1/en not_active Ceased
- 2001-04-17 ES ES01928133T patent/ES2267758T3/es not_active Expired - Lifetime
- 2001-04-17 RU RU2002130710/04A patent/RU2281282C2/ru not_active IP Right Cessation
- 2001-04-17 JP JP2001576775A patent/JP5066638B2/ja not_active Expired - Lifetime
- 2001-04-17 HR HRP20020825 patent/HRP20020825A2/hr not_active Application Discontinuation
- 2001-04-17 DK DK01928133T patent/DK1274685T3/da active
- 2001-04-17 AT AT01928133T patent/ATE332894T1/de not_active IP Right Cessation
- 2001-04-17 PL PL35982601A patent/PL359826A1/xx not_active IP Right Cessation
- 2001-04-17 US US10/257,755 patent/US7126002B2/en not_active Expired - Lifetime
- 2001-04-17 SK SK1508-2002A patent/SK287606B6/sk not_active IP Right Cessation
- 2001-04-17 UA UA2002108255A patent/UA75353C2/uk unknown
- 2001-04-17 CN CN018108318A patent/CN1216868C/zh not_active Expired - Lifetime
- 2001-04-17 SI SI200130607T patent/SI1274685T1/sl unknown
- 2001-04-17 IL IL15233701A patent/IL152337A0/xx active IP Right Grant
- 2001-04-17 AU AU5499701A patent/AU5499701A/xx active Pending
- 2001-04-17 EE EEP200200591A patent/EE05085B1/xx not_active IP Right Cessation
- 2001-04-17 CZ CZ20023445A patent/CZ301576B6/cs not_active IP Right Cessation
- 2001-04-17 CA CA2406266A patent/CA2406266C/en not_active Expired - Lifetime
- 2001-04-17 PT PT01928133T patent/PT1274685E/pt unknown
- 2001-04-17 BR BRPI0110184A patent/BRPI0110184B8/pt not_active IP Right Cessation
2002
- 2002-10-16 BG BG107199A patent/BG65889B1/bg unknown
- 2002-10-17 IL IL152337A patent/IL152337A/en unknown
- 2002-10-18 NO NO20025015A patent/NO323535B1/no not_active IP Right Cessation
- 2002-10-18 ZA ZA200208460A patent/ZA200208460B/en unknown
2006
- 2006-07-21 CY CY20061101020T patent/CY1107473T1/el unknown

Also Published As

Publication number	Publication date
RU2281282C2 (ru)	2006-08-10
KR100742482B1 (ko)	2007-07-25
AU5499701A (en)	2001-10-30
BR0110184A (pt)	2003-06-17
BG107199A (bg)	2003-07-31
HK1055741A1 (en)	2004-01-21
WO2001079174A1 (en)	2001-10-25
EE200200591A (et)	2004-04-15
CN1434800A (zh)	2003-08-06
KR20030011309A (ko)	2003-02-07
EP1274685A1 (en)	2003-01-15
RS51003B (sr)	2010-10-31
HUP0001583D0 (en)	2000-06-28
US7126002B2 (en)	2006-10-24
BRPI0110184B1 (pt)	2015-12-29
WO2001079174A8 (en)	2002-12-27
DE60121431D1 (de)	2006-08-24
PL359826A1 (en)	2004-09-06
CY1107473T1 (el)	2012-12-19
CZ20023445A3 (cs)	2003-03-12
UA75353C2 (en)	2006-04-17
DK1274685T3 (da)	2006-11-06
BRPI0110184B8 (pt)	2021-05-25
SI1274685T1 (sl)	2006-10-31
US20040006232A1 (en)	2004-01-08
RU2002130710A (ru)	2004-03-20
PT1274685E (pt)	2006-09-29
DE60121431T2 (de)	2007-01-18
CA2406266C (en)	2010-07-20
MXPA02010320A (es)	2004-09-06
HUP0001583A2 (hu)	2002-11-28
JP5066638B2 (ja)	2012-11-07
ATE332894T1 (de)	2006-08-15
ES2267758T3 (es)	2007-03-16
NO20025015L (no)	2002-12-16
JP2004501080A (ja)	2004-01-15
HRP20020825A2 (en)	2004-12-31
SK287606B6 (sk)	2011-03-04
IL152337A (en)	2007-10-31
EP1274685B1 (en)	2006-07-12
EE05085B1 (et)	2008-10-15
BG65889B1 (bg)	2010-04-30
ZA200208460B (en)	2003-10-20
CN1216868C (zh)	2005-08-31
SK15082002A3 (sk)	2003-05-02
NO323535B1 (no)	2007-06-04
AU2001254997B2 (en)	2006-11-23
NO20025015D0 (no)	2002-10-18
YU78302A (sh)	2005-09-19
NZ522017A (en)	2004-06-25
CA2406266A1 (en)	2001-10-25
CZ301576B6 (cs)	2010-04-21

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AU5499701A (en)	2001-10-30	A pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds
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Legal Events

Date	Code	Title	Description
2008-03-23	FF	Patent granted
2008-04-13	KB	Patent renewed