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IL151018A0 - Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha - Google Patents

Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha

Info

Publication number
IL151018A0
IL151018A0 IL15101801A IL15101801A IL151018A0 IL 151018 A0 IL151018 A0 IL 151018A0 IL 15101801 A IL15101801 A IL 15101801A IL 15101801 A IL15101801 A IL 15101801A IL 151018 A0 IL151018 A0 IL 151018A0
Authority
IL
Israel
Prior art keywords
tnf
inhibitors
beta
alpha
amino acid
Prior art date
Application number
IL15101801A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of IL151018A0 publication Critical patent/IL151018A0/xx

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    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
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    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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IL15101801A 2000-03-17 2001-03-15 Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha IL151018A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19018300P 2000-03-17 2000-03-17
US23546700P 2000-09-26 2000-09-26
US25206200P 2000-11-20 2000-11-20
PCT/US2001/008336 WO2001070734A2 (en) 2000-03-17 2001-03-15 Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha

Publications (1)

Publication Number Publication Date
IL151018A0 true IL151018A0 (en) 2003-02-12

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IL15101801A IL151018A0 (en) 2000-03-17 2001-03-15 Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha

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US (1) US6495565B2 (es)
EP (1) EP1263756B1 (es)
JP (1) JP2003528097A (es)
CN (1) CN1420881A (es)
AR (1) AR035174A1 (es)
AT (1) ATE260272T1 (es)
AU (1) AU2001250850A1 (es)
BR (1) BR0109469A (es)
CA (1) CA2400168A1 (es)
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ES (1) ES2215893T3 (es)
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NZ521245A (en) 2004-04-30
WO2001070734A3 (en) 2002-03-14
EP1263756A2 (en) 2002-12-11
HK1049334B (en) 2004-07-16
AU2001250850A1 (en) 2001-10-03
DE60102137T2 (de) 2004-10-21
DE60102137D1 (de) 2004-04-01
US6495565B2 (en) 2002-12-17
US20020013341A1 (en) 2002-01-31
CN1420881A (zh) 2003-05-28
BR0109469A (pt) 2003-04-29
ATE260272T1 (de) 2004-03-15
CA2400168A1 (en) 2001-09-27
WO2001070734A2 (en) 2001-09-27
AR035174A1 (es) 2004-05-05
JP2003528097A (ja) 2003-09-24

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