IL147214A0 - 1-methylcarbapenem derivatives and pharmaceutical compositions containing the same - Google Patents

1-methylcarbapenem derivatives and pharmaceutical compositions containing the same

Info

Publication number: IL147214A0
Authority: IL; Israel
Prior art keywords: same; pharmaceutical compositions; compositions containing; methylcarbapenem derivatives; methylcarbapenem
Prior art date: 1999-07-06

Application number

IL14721400A

Other languages

English (en)

Original Assignee

Sankyo Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-07-06

Filing date

2000-07-06

Publication date

2002-08-14

2000-07-06 Application filed by Sankyo Co filed Critical Sankyo Co

2002-08-14 Publication of IL147214A0 publication Critical patent/IL147214A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IL14721400A 1999-07-06 2000-07-06 1-methylcarbapenem derivatives and pharmaceutical compositions containing the same IL147214A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP19136899		1999-07-06
PCT/JP2000/004496 WO2001002401A1 (en)	1999-07-06	2000-07-06	Crystalline 1-methylcarbapenem compounds

Publications (1)

Publication Number	Publication Date
IL147214A0 true IL147214A0 (en)	2002-08-14

Family

ID=16273433

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL14721400A IL147214A0 (en)	1999-07-06	2000-07-06	1-methylcarbapenem derivatives and pharmaceutical compositions containing the same
IL147214A IL147214A (en)	1999-07-06	2001-12-20	1-methylcarbapenem derivatives and pharmaceutical compositions containing the same

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL147214A IL147214A (en)	1999-07-06	2001-12-20	1-methylcarbapenem derivatives and pharmaceutical compositions containing the same

Country Status (21)

Country	Link
US (3)	US20020128254A1 (es)
EP (1)	EP1193269A4 (es)
JP (1)	JP3476420B2 (es)
KR (1)	KR100750552B1 (es)
CN (2)	CN100360530C (es)
AU (1)	AU758190B2 (es)
BR (1)	BR0012253A (es)
CA (1)	CA2378483C (es)
CZ (1)	CZ20014731A3 (es)
HK (1)	HK1044768A1 (es)
HU (1)	HUP0202255A3 (es)
IL (2)	IL147214A0 (es)
MX (1)	MXPA02000061A (es)
NO (1)	NO327786B1 (es)
NZ (1)	NZ516310A (es)
PL (1)	PL352296A1 (es)
RU (2)	RU2214411C2 (es)
TR (2)	TR200403436T2 (es)
TW (1)	TWI250160B (es)
WO (1)	WO2001002401A1 (es)
ZA (1)	ZA200110413B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20020060067A (ko)	1999-04-06	2002-07-16	가와무라 요시부미	α-치환 카르복실산 유도체
US7041660B2 (en) *	1999-07-06	2006-05-09	Sankyo Company, Limited	Crystalline 1-methylcarbapenem derivatives
ATE267831T1 (de) *	1999-09-30	2004-06-15	Otsuka Kagaku Kk	Kristalle von cephemderivaten und verfahren zu ihrer herstellung
PT1294361E (pt)	2000-06-21	2011-07-26	Cubist Pharm Inc	Composições e métodos para melhorar a absorção oral de agentes antimicrobianos
KR100451672B1 (ko) *	2001-06-05	2004-10-08	한미약품 주식회사	결정성 세프디니르 산부가염, 이의 제조방법 및 이를이용한 세프디니르의 제조방법
EP1426376A4 (en) *	2001-08-13	2004-12-22	Eisai Co Ltd	PROCESS FOR THE PREPARATION OF CARBAPENEM-BASED ANTIBIOTICS
HRP20040264B1 (en) *	2001-09-26	2012-07-31	Merck@Sharp@@@Dohme@Corp	Process for making carbapenem compounds
ATE518864T1 (de) *	2001-09-26	2011-08-15	Merck Sharp & Dohme	Verfahren zur herstellung von carbapenemverbindungen
ITMI20012364A1 (it) *	2001-11-09	2003-05-09	Antibioticos Spa	Processo di sintesi della cefixima via alchil-o arilsolfonati
CN100475817C (zh) *	2003-08-25	2009-04-08	三共株式会社	1-甲基碳青霉烯化合物的结晶
JP2005097278A (ja) *	2003-08-25	2005-04-14	Sankyo Co Ltd	１−メチルカルバペネム化合物の結晶
EP1776365B1 (en) *	2004-06-02	2011-08-03	Sandoz Ag	Meropenem intermediate in crystalline form
EP1862456A4 (en) *	2005-03-22	2010-01-27	Daiichi Sankyo Co Ltd	PROCESS FOR PREPARING A CARBAPENE DERIVATIVE WITH 1-ALKYLPYRROLIDINE STRUCTURE
US8968781B2 (en)	2005-04-29	2015-03-03	Cubist Pharmaceuticals, Inc.	Therapeutic compositions
JPWO2006121151A1 (ja) *	2005-05-13	2008-12-18	第一三共株式会社	１−メチルカルバペネム化合物の結晶
CN101328179B (zh) *	2007-06-15	2011-01-12	山东轩竹医药科技有限公司	含有氧代氮杂环的巯基吡咯烷培南衍生物
CN101412717B (zh) *	2007-10-19	2011-01-12	山东轩竹医药科技有限公司	含有胍基烷酰胺基杂环的碳青霉烯衍生物
WO2009091031A1 (ja) *	2008-01-17	2009-07-23	Dainippon Sumitomo Pharma Co., Ltd.	アデニン化合物の製造方法
WO2011143935A1 (zh) *	2010-05-21	2011-11-24	山东轩竹医药科技有限公司	碳青霉烯衍生物或其水合物的晶型及其制备方法与用途
US8822445B2 (en) *	2010-06-03	2014-09-02	Xuanzhu Pharma Co., Ltd.	Crystalline form of carbapenem derivative or its hydrates and preparation methods and uses thereof
EP2945929B1 (de) *	2013-01-15	2020-01-22	Merck Patent GmbH	Acylguanidine zur behandlung von arthrose

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4260543A (en)	1978-07-03	1981-04-07	Merck & Co., Inc.	Crystalline N-formimidoyl thienamycin
US4748238A (en)	1984-03-14	1988-05-31	Merck & Co., Inc.	Crystalline 1R,5S,6S,8R-1-methyl-2-(N,N-dimethylcarbamimidoylmethylthio)-6-(1-hydroxyethyl)-1-carbapen-2-em-3-carboxylic acid
US4713451A (en)	1984-04-09	1987-12-15	Merck & Co., Inc.	Crystalline dimethyliminothienamycin
IE60588B1 (en)	1986-07-30	1994-07-27	Sumitomo Pharma	Carbapenem compound in crystalline form, and its production and use
US4866171A (en)	1987-04-11	1989-09-12	Lederle (Japan), Ltd.	(1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazolium-6-yl)]thio-6-[R-1-hydroxyethyl]-1-methyl-carbapenum-3-carboxylate
CA2036163C (en) *	1990-02-14	2001-06-19	Makoto Sunagawa	Novel beta-lactam compounds and their production
TW209220B (es) *	1991-11-27	1993-07-11	Manyu Seiyaku Kk
GB9202298D0 (en) *	1992-02-04	1992-03-18	Ici Plc	Antibiotic compounds
DE69324106T2 (de)	1992-11-17	1999-12-09	Sankyo Co., Ltd.	Krystallines Carbapenemderivat
JPH06336483A (ja) *	1993-05-26	1994-12-06	Banyu Pharmaceut Co Ltd	アミノアルキルピロリジニルチオカルバペネム誘導体
JPH07291973A (ja) *	1994-04-27	1995-11-07	Banyu Pharmaceut Co Ltd	新規な２−ピロリジニルチオカルバペネム誘導体
JPH09110869A (ja) *	1995-10-23	1997-04-28	Lederle Japan Ltd	カルバペネム化合物
DK0882728T3 (da) *	1995-12-21	2003-01-06	Sankyo Co	1-methylcarbapenemderivater
JP2955276B2 (ja) *	1997-06-19	1999-10-04	三共株式会社	１−メチルカルバペネム誘導体を含有する抗菌剤

2000
- 2000-07-05 TW TW089113337A patent/TWI250160B/zh not_active IP Right Cessation
- 2000-07-06 TR TR2004/03436T patent/TR200403436T2/xx unknown
- 2000-07-06 BR BR0012253-0A patent/BR0012253A/pt not_active Application Discontinuation
- 2000-07-06 EP EP00944289A patent/EP1193269A4/en not_active Withdrawn
- 2000-07-06 KR KR1020027000117A patent/KR100750552B1/ko not_active Expired - Fee Related
- 2000-07-06 HU HU0202255A patent/HUP0202255A3/hu unknown
- 2000-07-06 HK HK02106273.3A patent/HK1044768A1/en unknown
- 2000-07-06 RU RU2002100058/04A patent/RU2214411C2/ru not_active IP Right Cessation
- 2000-07-06 MX MXPA02000061A patent/MXPA02000061A/es active IP Right Grant
- 2000-07-06 CN CNB008124558A patent/CN100360530C/zh not_active Expired - Fee Related
- 2000-07-06 NZ NZ516310A patent/NZ516310A/en not_active IP Right Cessation
- 2000-07-06 CZ CZ20014731A patent/CZ20014731A3/cs unknown
- 2000-07-06 IL IL14721400A patent/IL147214A0/xx unknown
- 2000-07-06 TR TR2002/00100T patent/TR200200100T2/xx unknown
- 2000-07-06 CA CA002378483A patent/CA2378483C/en not_active Expired - Fee Related
- 2000-07-06 PL PL00352296A patent/PL352296A1/xx not_active Application Discontinuation
- 2000-07-06 JP JP2000204430A patent/JP3476420B2/ja not_active Expired - Fee Related
- 2000-07-06 WO PCT/JP2000/004496 patent/WO2001002401A1/ja not_active Ceased
- 2000-07-06 CN CNA2007101096355A patent/CN101077869A/zh active Pending
- 2000-07-06 AU AU58487/00A patent/AU758190B2/en not_active Ceased
2001
- 2001-12-19 ZA ZA200110413A patent/ZA200110413B/xx unknown
- 2001-12-20 IL IL147214A patent/IL147214A/en not_active IP Right Cessation
- 2001-12-28 US US10/034,548 patent/US20020128254A1/en not_active Abandoned
2002
- 2002-01-04 NO NO20020030A patent/NO327786B1/no not_active IP Right Cessation
2003
- 2003-01-27 US US10/351,944 patent/US6924279B2/en not_active Expired - Fee Related
- 2003-04-03 US US10/407,546 patent/US20030232803A1/en not_active Abandoned
- 2003-06-18 RU RU2003118411/04A patent/RU2003118411A/ru not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR100750552B1 (ko)	2007-08-20
MXPA02000061A (es)	2002-07-02
WO2001002401A1 (en)	2001-01-11
CA2378483C (en)	2008-09-16
US6924279B2 (en)	2005-08-02
TWI250160B (en)	2006-03-01
HK1044768A1 (en)	2002-11-01
CN100360530C (zh)	2008-01-09
AU5848700A (en)	2001-01-22
JP3476420B2 (ja)	2003-12-10
JP2001072681A (ja)	2001-03-21
HUP0202255A2 (en)	2002-10-28
AU758190B2 (en)	2003-03-20
TR200403436T2 (tr)	2005-03-21
IL147214A (en)	2009-12-24
PL352296A1 (en)	2003-08-11
CA2378483A1 (en)	2001-01-11
CN1372560A (zh)	2002-10-02
CZ20014731A3 (cs)	2002-04-17
RU2003118411A (ru)	2004-12-20
US20020128254A1 (en)	2002-09-12
US20030232803A1 (en)	2003-12-18
CN101077869A (zh)	2007-11-28
NO327786B1 (no)	2009-09-21
KR20020022761A (ko)	2002-03-27
EP1193269A1 (en)	2002-04-03
ZA200110413B (en)	2003-03-19
HUP0202255A3 (en)	2003-10-28
US20030158174A1 (en)	2003-08-21
TR200200100T2 (tr)	2002-05-21
BR0012253A (pt)	2002-03-26
RU2214411C2 (ru)	2003-10-20
NO20020030L (no)	2002-03-05
NZ516310A (en)	2004-05-28
NO20020030D0 (no)	2002-01-04
EP1193269A4 (en)	2003-05-28

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