IL133709A0 - Device for optimized electrotransfer of nucleic acid vectors to tissues in vivo - Google Patents
Device for optimized electrotransfer of nucleic acid vectors to tissues in vivoInfo
- Publication number
- IL133709A0 IL133709A0 IL13370998A IL13370998A IL133709A0 IL 133709 A0 IL133709 A0 IL 133709A0 IL 13370998 A IL13370998 A IL 13370998A IL 13370998 A IL13370998 A IL 13370998A IL 133709 A0 IL133709 A0 IL 133709A0
- Authority
- IL
- Israel
- Prior art keywords
- electrotransfer
- tissues
- vivo
- optimized
- nucleic acid
- Prior art date
Links
- 238000001727 in vivo Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9708232A FR2765241B1 (fr) | 1997-06-30 | 1997-06-30 | Amelioration du transfert d'acide nucleique dans les cellules d'organismes eucaryotes pluricellulaires et combinaison permettant la mise en oeuvre du procede |
| FR9708233A FR2765242B1 (fr) | 1997-06-30 | 1997-06-30 | Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede |
| US6748797P | 1997-12-01 | 1997-12-01 | |
| US6748897P | 1997-12-01 | 1997-12-01 | |
| US8385898P | 1998-05-01 | 1998-05-01 | |
| PCT/EP1998/003976 WO1999001175A1 (fr) | 1997-06-30 | 1998-06-30 | Dispositif permettant un transfert in vivo optimise de vecteurs d'acides nucleiques dans des tissus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL133709A0 true IL133709A0 (en) | 2001-04-30 |
Family
ID=27515625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13370998A IL133709A0 (en) | 1997-06-30 | 1998-06-30 | Device for optimized electrotransfer of nucleic acid vectors to tissues in vivo |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0993318A1 (fr) |
| JP (1) | JP2002515816A (fr) |
| KR (1) | KR20010014298A (fr) |
| CN (1) | CN1261812A (fr) |
| AU (1) | AU8730798A (fr) |
| BR (1) | BR9810500A (fr) |
| CA (1) | CA2295029A1 (fr) |
| IL (1) | IL133709A0 (fr) |
| NO (1) | NO996540L (fr) |
| PL (1) | PL337617A1 (fr) |
| WO (1) | WO1999001175A1 (fr) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2753379B1 (fr) | 1996-09-13 | 1998-10-30 | Rhone Poulenc Rorer Sa | Methode de traitement de la sclerose laterale amyotrophique |
| US6261281B1 (en) | 1997-04-03 | 2001-07-17 | Electrofect As | Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells |
| CA2361601A1 (fr) * | 1999-02-08 | 2000-08-10 | Cheryl Goldbeck | Augmentation electriquement induite de l'immunite et de l'efficacite de vaccins d'adn in vivo |
| ATE511856T1 (de) | 2000-03-13 | 2011-06-15 | Cornell Res Foundation Inc | Blockieren der leukozytenemigration und entzündung durch störung mit cd99/hec2 |
| IL151348A0 (en) | 2000-04-13 | 2003-04-10 | Univ Rockefeller | Enhancement of antibody-mediated immune responses |
| AU2001264759B2 (en) | 2000-05-22 | 2006-06-01 | Merck & Co., Inc. | System and method for assessing the performance of a pharmaceutical agent delivery system |
| KR20030074680A (ko) | 2000-12-28 | 2003-09-19 | 와이어쓰 | 스트렙토코커스 뉴모니에 유래 재조합 보호 단백질 |
| US20030039660A1 (en) | 2001-03-02 | 2003-02-27 | The Rockefeller University | Recombinant hybrid allergen constructs with reduced allergenicity that retain immunogenicity of the natural allergen |
| US20020198567A1 (en) * | 2001-06-07 | 2002-12-26 | Yona Keisari | Electro-endocytotic therapy as a treatment modality of cancer |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| US20050154434A1 (en) | 2002-03-07 | 2005-07-14 | Adam Simon | Clinical syringe with electrical stimulation aspects |
| NZ536475A (en) | 2002-05-24 | 2008-06-30 | Schering Corp | Neutralizing human anti-igfr antibody |
| US7785608B2 (en) | 2002-08-30 | 2010-08-31 | Wyeth Holdings Corporation | Immunogenic compositions for the prevention and treatment of meningococcal disease |
| EP1759714A1 (fr) * | 2005-09-02 | 2007-03-07 | Bioalliance Pharma | Electrotransfert d'acides nucléiques dans des cellules tissulaires |
| JP2009520509A (ja) * | 2005-10-03 | 2009-05-28 | ノヴォキュアー・リミテッド | 増殖細胞における電場の効果を増大させるための電場の最適化特性 |
| JP4961137B2 (ja) * | 2005-12-14 | 2012-06-27 | 久光製薬株式会社 | イオントフォレーシス用デバイス |
| ES2501947T3 (es) | 2006-10-19 | 2014-10-02 | Csl Limited | Antagonistas de anticuerpos de alta afinidad del receptor alfa 1 de interleucina |
| CA2666682C (fr) | 2006-10-19 | 2014-07-08 | Merck & Co., Inc. | Anticorps diriges contre il-13r.alpha.1 et leurs utilisations |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| US8246176B2 (en) | 2007-03-06 | 2012-08-21 | Sanyo Electric Co., Ltd. | Projection display device having an operation section for displacing a lens |
| US8093043B2 (en) | 2008-06-04 | 2012-01-10 | New York University | β-TrCP1, β-TrCP2 and RSK1 or RSK2 inhibitors and methods for sensitizing target cells to apoptosis |
| CN102124102B (zh) * | 2008-07-18 | 2013-12-18 | 麦克赛特股份有限公司 | 优化电穿孔的方法 |
| NZ614064A (en) | 2008-11-05 | 2015-04-24 | Wyeth Llc | Multicomponent immunogenic composition for the prevention of beta-hemolytic streptococcal (bhs) disease |
| HRP20210242T4 (hr) | 2010-08-23 | 2024-05-10 | Wyeth Llc | Stabilne formulacije antigena iz bakterije neisseria meningitidis rlp2086 |
| RU2546873C2 (ru) | 2010-09-10 | 2015-04-10 | УАЙТ ЭлЭлСи | Нелипидизированные варианты антигенов neisseria meningitidis orf2086 |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| JP5925342B2 (ja) | 2012-03-09 | 2016-05-25 | ファイザー・インク | 髄膜炎菌(Neisseriameningitidis)組成物およびその方法 |
| WO2014107739A1 (fr) | 2013-01-07 | 2014-07-10 | Eleven Biotherapeutics, Inc. | Anticorps dirigés contre pcsk9 |
| EP2964665B1 (fr) | 2013-03-08 | 2018-08-01 | Pfizer Inc | Polypeptides immunogènes de fusion |
| MX380129B (es) | 2013-09-08 | 2025-03-11 | Pfizer | Composiciones de neisseria meningitidis y sus metodos |
| RU2723045C2 (ru) | 2015-02-19 | 2020-06-08 | Пфайзер Инк. | Композиции neisseria meningitidis и способы их получения |
| IL303108B2 (en) | 2017-01-31 | 2024-07-01 | Pfizer | NEISSERIA MENINGITIDIS preparations and methods therefor |
| CN110527625A (zh) * | 2018-05-24 | 2019-12-03 | 苏州壹达生物科技有限公司 | 一种结合高压和低压模式的流式电转染装置 |
| US12383611B2 (en) | 2019-09-27 | 2025-08-12 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9317380D0 (en) * | 1993-08-20 | 1993-10-06 | Therexsys Ltd | Transfection process |
| US5641680A (en) * | 1994-11-14 | 1997-06-24 | Zhao; Xi | Gene transfer apparatus and method for using the same |
| WO1997007826A1 (fr) * | 1995-08-29 | 1997-03-06 | Cbr Laboratories, Inc. | Electroporation in vivo de cellules |
-
1998
- 1998-06-30 WO PCT/EP1998/003976 patent/WO1999001175A1/fr not_active Ceased
- 1998-06-30 CA CA002295029A patent/CA2295029A1/fr not_active Abandoned
- 1998-06-30 AU AU87307/98A patent/AU8730798A/en not_active Abandoned
- 1998-06-30 CN CN98806793A patent/CN1261812A/zh active Pending
- 1998-06-30 PL PL98337617A patent/PL337617A1/xx not_active Application Discontinuation
- 1998-06-30 KR KR1019997012430A patent/KR20010014298A/ko not_active Withdrawn
- 1998-06-30 BR BR9810500-0A patent/BR9810500A/pt not_active IP Right Cessation
- 1998-06-30 JP JP50807599A patent/JP2002515816A/ja active Pending
- 1998-06-30 IL IL13370998A patent/IL133709A0/xx unknown
- 1998-06-30 EP EP98938676A patent/EP0993318A1/fr not_active Ceased
-
1999
- 1999-12-29 NO NO996540A patent/NO996540L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BR9810500A (pt) | 2000-09-05 |
| CA2295029A1 (fr) | 1999-01-14 |
| EP0993318A1 (fr) | 2000-04-19 |
| AU8730798A (en) | 1999-01-25 |
| KR20010014298A (ko) | 2001-02-26 |
| PL337617A1 (en) | 2000-08-28 |
| WO1999001175A1 (fr) | 1999-01-14 |
| NO996540D0 (no) | 1999-12-29 |
| JP2002515816A (ja) | 2002-05-28 |
| CN1261812A (zh) | 2000-08-02 |
| NO996540L (no) | 2000-02-03 |
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