IL139140A0 - Cyclopentanone dihydropyridine compounds useful as potassium channel openers - Google Patents

Cyclopentanone dihydropyridine compounds useful as potassium channel openers

Info

Publication number: IL139140A0
Authority: IL; Israel
Prior art keywords: cyclopentanone; compounds useful; potassium channel; channel openers; dihydropyridine compounds
Prior art date: 1999-03-04

Application number

IL13914000A

Other languages

English (en)

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-04

Filing date

2000-03-06

Publication date

2001-11-25

2000-03-06 Application filed by Abbott Lab filed Critical Abbott Lab

2001-11-25 Publication of IL139140A0 publication Critical patent/IL139140A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL13914000A 1999-03-04 2000-03-06 Cyclopentanone dihydropyridine compounds useful as potassium channel openers IL139140A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/262,441 US6518279B2 (en)	1999-03-04	1999-03-04	Cyclopentanone dihydropyridine compounds useful as potassium channel openers
PCT/US2000/005828 WO2000051986A1 (en)	1999-03-04	2000-03-06	Cyclopentanone dihydropyridine compounds useful as potassium channel openers

Publications (1)

Publication Number	Publication Date
IL139140A0 true IL139140A0 (en)	2001-11-25

Family

ID=22997528

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13914000A IL139140A0 (en)	1999-03-04	2000-03-06	Cyclopentanone dihydropyridine compounds useful as potassium channel openers

Country Status (20)

Country	Link
US (1)	US6518279B2 (hu)
EP (1)	EP1075466A1 (hu)
JP (1)	JP2003517454A (hu)
KR (1)	KR20010043295A (hu)
CN (1)	CN1318053A (hu)
AR (1)	AR028987A1 (hu)
AU (1)	AU3616800A (hu)
BG (1)	BG104999A (hu)
BR (1)	BR0005189A (hu)
CA (1)	CA2330541A1 (hu)
CO (1)	CO5150208A1 (hu)
HU (1)	HUP0102895A3 (hu)
IL (1)	IL139140A0 (hu)
MX (1)	MXPA00010790A (hu)
NO (1)	NO20005570L (hu)
PL (1)	PL343883A1 (hu)
SK (1)	SK18152000A3 (hu)
TR (1)	TR200003202T1 (hu)
WO (1)	WO2000051986A1 (hu)
ZA (1)	ZA200005798B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6265417B1 (en)	1997-12-18	2001-07-24	Abbott Laboratories	Potassium channel openers
US6593335B1 (en) *	1997-12-18	2003-07-15	Abbott Laboratories	Potassium channel openers
EP1307429B1 (en) *	2000-08-02	2007-11-28	AstraZeneca AB	Process for asymmetric synthesis of substituted 1,4-dihydropyridines
US20030045449A1 (en) *	2001-08-15	2003-03-06	Pfizer, Inc.	Pharmaceutical combinations for the treatment of neurodegenerative diseases
US20030199578A1 (en) *	2002-04-19	2003-10-23	Turner Sean C.	Naphthalene amides as potassium channel openers
CN101415690A (zh) *	2006-02-10	2009-04-22	詹森药业有限公司	作为钾通道开放剂的新的三环二氢吡嗪化合物
WO2010094405A1 (en)	2009-02-18	2010-08-26	Bayer Schering Pharma Aktiengesellschaft	Bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives and uses thereof
WO2021253180A1 (en) *	2020-06-15	2021-12-23	Novartis Ag	Methyl (r) -2- (fluoromethyl) -5-oxo-4-phenyl-4, 5, 6, 7-tetrahydro-1h-cyclopenta [b] pyridine-3-carboxylate and methyl (r) -2- (fluoromethyl) -5-oxo-4-phenyl-1, 4, 5, 7-tetrahydrofuro [3, 4-b] pyridine-3-carboxylate as cav1.2 activators
US11939316B1 (en)	2023-11-06	2024-03-26	King Faisal University	9-(6-flouro-2-hydroxyouinolin-3-yl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,6,7,9,10-hexhydroacridine-1,8(2h,5h)-dione as an antimicrobial compound
US11970478B1 (en)	2023-11-16	2024-04-30	King Faisal University	9-(2-hydroxyquinolin-3-yl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine1,8(2H,5H)-dione as an antimicrobial compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2003148A1 (de)	1970-01-24	1971-07-29	Bayer Ag	Neue 1,4-Dihydropyridinderivate
DE3447170A1 (de)	1984-12-22	1986-07-03	Bayer Ag, 5090 Leverkusen	Mischung unterschiedlicher dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
GB8716971D0 (en)	1987-07-17	1987-08-26	Pfizer Ltd	Therapeutic agents
GB8907401D0 (en)	1989-04-01	1989-05-17	Pfizer Ltd	Therapeutic agents
JP3285963B2 (ja)	1991-10-21	2002-05-27	インペリアル・ケミカル・インダストリーズ・ピーエルシー	治療剤
GB9220570D0 (en)	1991-10-21	1992-11-11	Ici Plc	Therapeutic agent
GB9318935D0 (en)	1992-10-20	1993-10-27	Zeneca Ltd	Heterocyclic derivatives
DE4313690A1 (de)	1993-04-27	1994-11-03	Bayer Ag	Kondensierte Chinolyl-dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
CN1158259C (zh)	1997-12-18	2004-07-21	艾博特公司	钾通道疏通剂

1999
- 1999-03-04 US US09/262,441 patent/US6518279B2/en not_active Expired - Fee Related
2000
- 2000-03-01 CO CO00014719A patent/CO5150208A1/es unknown
- 2000-03-02 AR ARP000100931A patent/AR028987A1/es not_active Application Discontinuation
- 2000-03-06 HU HU0102895A patent/HUP0102895A3/hu unknown
- 2000-03-06 CN CN00800760A patent/CN1318053A/zh active Pending
- 2000-03-06 KR KR1020007012257A patent/KR20010043295A/ko not_active Withdrawn
- 2000-03-06 WO PCT/US2000/005828 patent/WO2000051986A1/en not_active Ceased
- 2000-03-06 PL PL00343883A patent/PL343883A1/xx not_active Application Discontinuation
- 2000-03-06 BR BR0005189-6A patent/BR0005189A/pt not_active IP Right Cessation
- 2000-03-06 TR TR2000/03202T patent/TR200003202T1/xx unknown
- 2000-03-06 MX MXPA00010790A patent/MXPA00010790A/es unknown
- 2000-03-06 EP EP00914832A patent/EP1075466A1/en not_active Withdrawn
- 2000-03-06 JP JP2000602213A patent/JP2003517454A/ja not_active Withdrawn
- 2000-03-06 CA CA002330541A patent/CA2330541A1/en not_active Abandoned
- 2000-03-06 AU AU36168/00A patent/AU3616800A/en not_active Abandoned
- 2000-03-06 IL IL13914000A patent/IL139140A0/xx unknown
- 2000-03-06 SK SK1815-2000A patent/SK18152000A3/sk unknown
- 2000-10-18 ZA ZA200005798A patent/ZA200005798B/en unknown
- 2000-11-03 NO NO20005570A patent/NO20005570L/no not_active Application Discontinuation
- 2000-11-28 BG BG104999A patent/BG104999A/xx unknown

Also Published As

Publication number	Publication date
CA2330541A1 (en)	2000-09-08
EP1075466A1 (en)	2001-02-14
AR028987A1 (es)	2003-06-04
AU3616800A (en)	2000-09-21
NO20005570D0 (no)	2000-11-03
HUP0102895A2 (hu)	2001-12-28
CN1318053A (zh)	2001-10-17
WO2000051986A1 (en)	2000-09-08
HUP0102895A3 (en)	2002-01-28
MXPA00010790A (es)	2002-06-04
NO20005570L (no)	2000-11-03
BG104999A (en)	2001-10-31
JP2003517454A (ja)	2003-05-27
KR20010043295A (ko)	2001-05-25
SK18152000A3 (sk)	2001-06-11
ZA200005798B (en)	2002-01-18
US6518279B2 (en)	2003-02-11
US20020007065A1 (en)	2002-01-17
CO5150208A1 (es)	2002-04-29
TR200003202T1 (tr)	2001-08-21
BR0005189A (pt)	2001-01-09
PL343883A1 (en)	2001-09-10

Publication	Publication Date	Title
AU5557700A (en)	2001-01-22	New uses for potassium channel openers
GB2390091B (en)	2005-10-05	Bisarylamines as potassium channel openers
AU1278701A (en)	2001-05-14	Novel compounds
AU2003294441A1 (en)	2004-06-18	1-aryl-2-hydroxyethyl amides as potassium channel openers
AUPQ441499A0 (en)	2000-01-06	Novel compound
IL139140A0 (en)	2001-11-25	Cyclopentanone dihydropyridine compounds useful as potassium channel openers
AU2003295781A1 (en)	2004-06-18	Arylcyclopropylcarboxylic amides as potassium channel openers
WO2002010164A3 (en)	2002-04-25	Dihydronaphthyridine- and dihydropyrrolopyridine-derivated compounds as potassium channel openers
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AU2109700A (en)	2000-08-07	Novel compounds
HK1037873A (en)	2002-02-22	Cyclopentanone dihydropyridine compounds useful as potassium channel openers
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AU2002306716A1 (en)	2002-10-03	Bisarylamines as potassium channel openers
AU2002253575A1 (en)	2002-11-11	Potassium channel opener
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AU2003203035A1 (en)	2003-09-02	1,4-dihydropyridine and pyridine compounds as calcium channel blockers
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SI1499590T1 (sl)	2006-10-31	Piperidinski derivati kot blokatorji kalijevih kanalov
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