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IL139132A0 - Benzothiophenes, benzofurans and indoles useful in the treatment of insulin resistance and hyperglycemia - Google Patents

Benzothiophenes, benzofurans and indoles useful in the treatment of insulin resistance and hyperglycemia

Info

Publication number
IL139132A0
IL139132A0 IL13913299A IL13913299A IL139132A0 IL 139132 A0 IL139132 A0 IL 139132A0 IL 13913299 A IL13913299 A IL 13913299A IL 13913299 A IL13913299 A IL 13913299A IL 139132 A0 IL139132 A0 IL 139132A0
Authority
IL
Israel
Prior art keywords
benzothiophenes
benzofurans
hyperglycemia
treatment
insulin resistance
Prior art date
Application number
IL13913299A
Other languages
English (en)
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IL139132A0 publication Critical patent/IL139132A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74—Naphthothiophenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
IL13913299A 1998-05-12 1999-05-10 Benzothiophenes, benzofurans and indoles useful in the treatment of insulin resistance and hyperglycemia IL139132A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7671298A 1998-05-12 1998-05-12
PCT/US1999/010209 WO1999061435A1 (en) 1998-05-12 1999-05-10 Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia

Publications (1)

Publication Number Publication Date
IL139132A0 true IL139132A0 (en) 2001-11-25

Family

ID=22133746

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13913299A IL139132A0 (en) 1998-05-12 1999-05-10 Benzothiophenes, benzofurans and indoles useful in the treatment of insulin resistance and hyperglycemia

Country Status (22)

Country Link
EP (1) EP1077969A1 (pt)
JP (1) JP2002516321A (pt)
KR (1) KR20010043539A (pt)
CN (1) CN1308626A (pt)
AR (1) AR015294A1 (pt)
AU (1) AU756337B2 (pt)
BG (1) BG104918A (pt)
BR (1) BR9911779A (pt)
CA (1) CA2330620A1 (pt)
EA (1) EA200001175A1 (pt)
EE (1) EE200000653A (pt)
HR (1) HRP20000767A2 (pt)
HU (1) HUP0101792A3 (pt)
ID (1) ID26244A (pt)
IL (1) IL139132A0 (pt)
NO (1) NO20005677L (pt)
PL (1) PL344081A1 (pt)
SK (1) SK16992000A3 (pt)
TR (1) TR200003333T2 (pt)
TW (1) TW510900B (pt)
WO (1) WO1999061435A1 (pt)
ZA (1) ZA200005961B (pt)

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US20020198202A1 (en) * 2001-06-07 2002-12-26 Wyeth Combination of a PTPase inhibitor and an antilipemic agent
US6734197B2 (en) 2001-06-07 2004-05-11 Wyeth Combination therapy for type II diabetes or Syndrome X
WO2002098414A1 (en) * 2001-06-07 2002-12-12 Wyeth Methods using ptpase inhibitors and insulin
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US20030055058A1 (en) * 2001-06-07 2003-03-20 Wyeth Combination of a PTPase inhibitor and an ACE inhibitor
US20030013709A1 (en) * 2001-06-07 2003-01-16 Wyeth Combination of a PTPase inhibitor and an alpha-glucosidase inhibitor
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DK1397130T3 (da) 2001-06-20 2007-11-12 Wyeth Corp Substituerede indolsyrederivater som inhibitorer af plasminogenaktivatorinhibitor-1 (PAI-1)
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US6984645B2 (en) 2001-11-16 2006-01-10 Bristol-Myers Squibb Company Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
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WO2004106542A1 (ja) 2003-05-29 2004-12-09 Sankyo Company, Limited インスリン抵抗性改善剤及びそのスクリーニング方法
US7504401B2 (en) 2003-08-29 2009-03-17 Locus Pharmaceuticals, Inc. Anti-cancer agents and uses thereof
US7420083B2 (en) 2003-09-25 2008-09-02 Wyeth Substituted aryloximes
US7268159B2 (en) 2003-09-25 2007-09-11 Wyeth Substituted indoles
US7141592B2 (en) 2003-09-25 2006-11-28 Wyeth Substituted oxadiazolidinediones
US7534894B2 (en) 2003-09-25 2009-05-19 Wyeth Biphenyloxy-acids
US7371759B2 (en) 2003-09-25 2008-05-13 Bristol-Myers Squibb Company HMG-CoA reductase inhibitors and method
US7411083B2 (en) 2003-09-25 2008-08-12 Wyeth Substituted acetic acid derivatives
US7442805B2 (en) 2003-09-25 2008-10-28 Wyeth Substituted sulfonamide-indoles
US7163954B2 (en) 2003-09-25 2007-01-16 Wyeth Substituted naphthyl benzothiophene acids
US7265148B2 (en) 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
US7351726B2 (en) 2003-09-25 2008-04-01 Wyeth Substituted oxadiazolidinediones
US7342039B2 (en) 2003-09-25 2008-03-11 Wyeth Substituted indole oximes
US7332521B2 (en) 2003-09-25 2008-02-19 Wyeth Substituted indoles
US7582773B2 (en) 2003-09-25 2009-09-01 Wyeth Substituted phenyl indoles
US7446201B2 (en) 2003-09-25 2008-11-04 Wyeth Substituted heteroaryl benzofuran acids
US7435837B2 (en) 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
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CN106749169B (zh) * 2016-11-07 2020-04-21 浙江工业大学 一种Ertiprotafib的手性制备方法
CN107033122B (zh) * 2017-05-19 2019-06-14 南方医科大学 一种n-芳基-2-噻吩酰胺类衍生物及其制备方法和用途
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Also Published As

Publication number Publication date
ZA200005961B (en) 2001-10-24
CN1308626A (zh) 2001-08-15
BR9911779A (pt) 2001-02-06
CA2330620A1 (en) 1999-12-02
NO20005677L (no) 2000-12-05
AR015294A1 (es) 2001-04-18
AU3893999A (en) 1999-12-13
HRP20000767A2 (en) 2001-10-31
TW510900B (en) 2002-11-21
ID26244A (id) 2000-12-07
AU756337B2 (en) 2003-01-09
WO1999061435A1 (en) 1999-12-02
NO20005677D0 (no) 2000-11-10
KR20010043539A (ko) 2001-05-25
JP2002516321A (ja) 2002-06-04
HUP0101792A3 (en) 2003-01-28
SK16992000A3 (sk) 2001-04-09
HUP0101792A2 (hu) 2002-01-28
TR200003333T2 (tr) 2001-02-21
BG104918A (bg) 2001-08-31
PL344081A1 (en) 2001-09-24
EP1077969A1 (en) 2001-02-28
EE200000653A (et) 2002-04-15
EA200001175A1 (ru) 2001-06-25

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