IL138160A0 - Quinoline derivatives - Google Patents
Quinoline derivativesInfo
- Publication number
- IL138160A0 IL138160A0 IL13816099A IL13816099A IL138160A0 IL 138160 A0 IL138160 A0 IL 138160A0 IL 13816099 A IL13816099 A IL 13816099A IL 13816099 A IL13816099 A IL 13816099A IL 138160 A0 IL138160 A0 IL 138160A0
- Authority
- IL
- Israel
- Prior art keywords
- quinoline derivatives
- quinoline
- derivatives
- Prior art date
Links
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9801474A SE9801474D0 (sv) | 1998-04-27 | 1998-04-27 | Quinoline Derivatives |
| PCT/SE1999/000676 WO1999055678A1 (fr) | 1998-04-27 | 1999-04-26 | Derives de quinoline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL138160A0 true IL138160A0 (en) | 2001-10-31 |
Family
ID=20411103
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13816099A IL138160A0 (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives |
| IL138160A IL138160A (en) | 1998-04-27 | 2000-08-30 | Quinoline derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL138160A IL138160A (en) | 1998-04-27 | 2000-08-30 | Quinoline derivatives |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP1073639B1 (fr) |
| JP (1) | JP4045069B2 (fr) |
| KR (1) | KR100571534B1 (fr) |
| CN (1) | CN1113057C (fr) |
| AP (1) | AP1293A (fr) |
| AT (1) | ATE228505T1 (fr) |
| AU (1) | AU747550B2 (fr) |
| BR (1) | BR9909925B1 (fr) |
| CA (1) | CA2329788C (fr) |
| CZ (1) | CZ297439B6 (fr) |
| DE (1) | DE69904162T2 (fr) |
| DK (1) | DK1073639T3 (fr) |
| EE (1) | EE04275B1 (fr) |
| ES (1) | ES2188242T3 (fr) |
| HR (1) | HRP20000726B1 (fr) |
| HU (1) | HU227709B1 (fr) |
| ID (1) | ID26277A (fr) |
| IL (2) | IL138160A0 (fr) |
| IS (1) | IS2082B (fr) |
| ME (1) | ME00870B (fr) |
| NO (1) | NO315606B1 (fr) |
| NZ (1) | NZ506641A (fr) |
| OA (1) | OA11547A (fr) |
| PL (1) | PL190441B1 (fr) |
| PT (1) | PT1073639E (fr) |
| RS (1) | RS50029B (fr) |
| RU (1) | RU2197481C2 (fr) |
| SE (1) | SE9801474D0 (fr) |
| TR (1) | TR200003061T2 (fr) |
| UA (1) | UA60354C2 (fr) |
| WO (1) | WO1999055678A1 (fr) |
| ZA (1) | ZA200004601B (fr) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0002320D0 (sv) * | 1999-10-25 | 2000-06-21 | Active Biotech Ab | Malignant tumors |
| SE0201778D0 (sv) * | 2002-06-12 | 2002-06-12 | Active Biotech Ab | Process for the manufacture of quinoline derivatives |
| KR100908655B1 (ko) | 2002-11-27 | 2009-07-21 | 엘지디스플레이 주식회사 | 데이터 공급시간의 변조방법과 이를 이용한액정표시장치의 구동방법 및 장치 |
| SE0400235D0 (sv) * | 2004-02-06 | 2004-02-06 | Active Biotech Ab | New composition containing quinoline compounds |
| SE0401578D0 (sv) * | 2004-06-18 | 2004-06-18 | Active Biotech Ab | Novel compounds |
| US7838522B2 (en) | 2004-11-17 | 2010-11-23 | Ares Trading S.A. | Benzothiazole formulations and use thereof |
| RS52193B (sr) | 2004-12-21 | 2012-10-31 | Merck Serono Sa. | Ciklični derivati sulfonil amina i njihova upotreba |
| DK1844032T3 (da) | 2005-01-31 | 2011-10-24 | Merck Serono Sa | N-hydroxyamid-derivater og deres anvendelse |
| BRPI0613042A2 (pt) | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
| KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 jnk 억제제 |
| AU2006286489B2 (en) | 2005-09-01 | 2012-08-09 | Ares Trading S.A. | Treatment of optic neuritis |
| SI1937642T1 (sl) * | 2005-10-19 | 2015-01-30 | Teva Pharmaceutical Industries Ltd. | Kristali natrijevega lakvinimoda in postopek za njihovo pripravo |
| CN101466379B (zh) * | 2006-06-12 | 2012-10-31 | 泰华制药工业有限公司 | 稳定的拉喹莫德的制剂 |
| EP2234485B1 (fr) | 2007-12-20 | 2013-11-13 | Teva Pharmaceutical Industries, Ltd. | Préparations de laquinimod stables |
| KR20110048571A (ko) | 2008-09-03 | 2011-05-11 | 테바 파마슈티컬 인더스트리즈 리미티드 | 면역 기능을 지닌 2―옥소―1,2―다이하이드로―퀴놀린 조절제 |
| RS54707B1 (sr) * | 2009-07-30 | 2016-08-31 | Teva Pharmaceutical Industries Ltd. | Tretman kronove bolesti lakvinimodom |
| PL2467372T3 (pl) * | 2009-08-10 | 2017-04-28 | Teva Pharmaceutical Industries Ltd. | Leczenie zaburzeń związanych z BDNF z zastosowaniem lakwinimodu |
| US8889661B2 (en) * | 2010-03-03 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of lupus nephritis using laquinimod |
| PH12012501741A1 (en) * | 2010-03-03 | 2012-11-12 | Teva Pharma | Treatment of lupus arthritis using laquinimod |
| KR20130014523A (ko) | 2010-03-03 | 2013-02-07 | 테바 파마슈티컬 인더스트리즈 리미티드 | 라퀴니모드 및 메토트렉세이트의 병용에 의한 류마티스 관절염의 치료 |
| WO2011116091A1 (fr) | 2010-03-17 | 2011-09-22 | Novartis Ag | Distributeur |
| AU2011275720B2 (en) * | 2010-07-09 | 2015-05-14 | Active Biotech Ab | Method for manufacturing of quinoline-3-carboxamides |
| SG186948A1 (en) | 2010-07-09 | 2013-02-28 | Teva Pharma | Deuterated n-ethyl-n-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, salts and uses thereof |
| KR20130041193A (ko) * | 2010-07-09 | 2013-04-24 | 테바 파마슈티컬 인더스트리즈 리미티드 | 5-클로로-4-하이드록시-1-메틸-2-옥소-n-페닐-1,2-다이하이드로퀴놀린-3-카복스아마이드, 염 및 그의 용도 |
| EP2444086A1 (fr) | 2010-10-22 | 2012-04-25 | Almirall, S.A. | Combinaisons comportant des inhibiteurs de DHODH et de COX |
| US8889627B2 (en) | 2011-10-12 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
| US9161935B2 (en) * | 2012-02-03 | 2015-10-20 | Teva Pharmaceutical Industries, Ltd. | Use of laquinimod for treating Crohn's disease patients who failed first-line anti-TNF therapy |
| EA201491517A1 (ru) | 2012-02-16 | 2015-03-31 | Тева Фармасьютикал Индастриз Лтд. | N-этил-n-фенил-1,2-дигидро-4,5-дигидрокси-1-метил-2-оксо-3-хинолинкарбоксамид, его получение и применения |
| TW201350467A (zh) | 2012-05-08 | 2013-12-16 | Teva Pharma | N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺 |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
| CN104955522A (zh) | 2012-11-07 | 2015-09-30 | 梯瓦制药工业有限公司 | 拉喹莫德胺盐 |
| RU2545056C2 (ru) * | 2012-12-10 | 2015-03-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия" Министерства здавоохранения и социального развития Российской Федерации (ГБОУ ВПО ПГФА Минздравсоцразвития России) | Противовоспалительное и анальгетическое средство на основе изопропиламида 1,2-дигидро-1н-2-оксоцинхониновой кислоты |
| CA2900503A1 (fr) * | 2013-02-15 | 2014-08-21 | Teva Pharmaceutical Industries Ltd. | Traitement de la sclerose en plaques a l'aide de laquinimod |
| WO2014153145A2 (fr) | 2013-03-14 | 2014-09-25 | Teva Pharmaceutical Industries Ltd. | Cristaux de sodium de laquinimod et procédé amélioré pour leur fabrication |
| WO2015168103A1 (fr) | 2014-04-29 | 2015-11-05 | Teva Pharmaceutical Industries Ltd. | Laquinimod pour le traitement de patients atteints de sclérose en plaques récurrente rémittente (sep-rr) chez ayant un degré d'incapacité élevé |
| WO2016042112A1 (fr) | 2014-09-23 | 2016-03-24 | Active Biotech Ab | Quinoléine carboxamides destinées à être utilisées dans le traitement du myélome multiple |
| ES2663836T3 (es) | 2014-11-19 | 2018-04-17 | Active Biotech Ab | Carboxamidas de quinolina para su uso en el tratamiento de leucemia |
| DK3886858T3 (da) * | 2019-12-19 | 2022-08-22 | Active Biotech Ab | Forbindelser til behandling af øjensygdomme forbundet med for megen vaskularisering |
| WO2021175924A1 (fr) | 2020-03-03 | 2021-09-10 | Active Biotech Ab | Tasquinimod ou sel pharmaceutiquement acceptable de celui-ci destiné à être utilisé en polythérapie |
| CA3179303A1 (fr) * | 2020-05-21 | 2021-11-25 | Darren Orton | Inhibiteurs de notch et leurs utilisations |
| US20230293512A1 (en) | 2020-07-23 | 2023-09-21 | Erasmus University Medical Center Rotterdam | S100 proteins as novel therapeutic targets in myeloproliferative neoplasms |
| JP2024503372A (ja) | 2021-01-18 | 2024-01-25 | アクティブ バイオテック エイビー | 骨髄異形成症候群の処置における使用のためのタスキニモドまたはその薬学的に許容される塩 |
| WO2022248401A1 (fr) | 2021-05-25 | 2022-12-01 | Active Biotech Ab | Pluralité de particules de tasquinimod et utilisation de celles-ci |
| IL309486A (en) | 2021-07-02 | 2024-02-01 | Active Biotech Ab | A pharmacy product containing tesquinimod and a method for evaluating the cleanliness of this product |
| AU2022421214A1 (en) * | 2021-12-20 | 2024-07-04 | The Johns Hopkins University | Compounds for treatment of cancer |
| WO2025083549A1 (fr) | 2023-10-16 | 2025-04-24 | Sun Pharma Advanced Research Company Limited | Méthodes et combinaisons d'inhibiteurs de la voie il-23 et de modulateurs de la voie de signalisation s1p pour le traitement de maladies auto-immunes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE52670B1 (en) * | 1981-03-03 | 1988-01-20 | Leo Ab | Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation |
| SU1735288A1 (ru) * | 1990-03-05 | 1992-05-23 | Харьковский государственный фармацевтический институт | Способ получени N-R-замещенных амидов 4-гидроксихинолон-2 карбоновой -3-кислоты |
| GB9108547D0 (en) * | 1991-04-22 | 1991-06-05 | Fujisawa Pharmaceutical Co | Quinoline derivatives |
| DE4120646A1 (de) * | 1991-06-22 | 1992-12-24 | Bayer Ag | 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate |
| US5428040A (en) * | 1993-08-31 | 1995-06-27 | The Du Pont Merck Pharmaceutical Company | Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents |
| SE9400810D0 (sv) * | 1994-03-10 | 1994-03-10 | Pharmacia Ab | New use of Quinoline-3-carboxamide compounds |
-
1998
- 1998-04-27 SE SE9801474A patent/SE9801474D0/xx unknown
-
1999
- 1999-04-26 CA CA002329788A patent/CA2329788C/fr not_active Expired - Fee Related
- 1999-04-26 ME MEP-2000-612A patent/ME00870B/fr unknown
- 1999-04-26 IL IL13816099A patent/IL138160A0/xx active IP Right Grant
- 1999-04-26 TR TR2000/03061T patent/TR200003061T2/xx unknown
- 1999-04-26 CZ CZ20003849A patent/CZ297439B6/cs not_active IP Right Cessation
- 1999-04-26 ES ES99947036T patent/ES2188242T3/es not_active Expired - Lifetime
- 1999-04-26 HR HR20000726A patent/HRP20000726B1/xx not_active IP Right Cessation
- 1999-04-26 BR BRPI9909925-0A patent/BR9909925B1/pt not_active IP Right Cessation
- 1999-04-26 CN CN99805581A patent/CN1113057C/zh not_active Expired - Fee Related
- 1999-04-26 RU RU2000129672/04A patent/RU2197481C2/ru not_active IP Right Cessation
- 1999-04-26 JP JP2000545838A patent/JP4045069B2/ja not_active Expired - Lifetime
- 1999-04-26 WO PCT/SE1999/000676 patent/WO1999055678A1/fr not_active Ceased
- 1999-04-26 OA OA1200000301A patent/OA11547A/en unknown
- 1999-04-26 DE DE69904162T patent/DE69904162T2/de not_active Expired - Lifetime
- 1999-04-26 AU AU43013/99A patent/AU747550B2/en not_active Ceased
- 1999-04-26 PL PL99343420A patent/PL190441B1/pl unknown
- 1999-04-26 ID IDW20002183A patent/ID26277A/id unknown
- 1999-04-26 AP APAP/P/2000/001933A patent/AP1293A/en active
- 1999-04-26 NZ NZ506641A patent/NZ506641A/en not_active IP Right Cessation
- 1999-04-26 EP EP99947036A patent/EP1073639B1/fr not_active Expired - Lifetime
- 1999-04-26 AT AT99947036T patent/ATE228505T1/de active
- 1999-04-26 HU HU0102084A patent/HU227709B1/hu not_active IP Right Cessation
- 1999-04-26 EE EEP200000613A patent/EE04275B1/xx unknown
- 1999-04-26 UA UA2000085078A patent/UA60354C2/uk unknown
- 1999-04-26 DK DK99947036T patent/DK1073639T3/da active
- 1999-04-26 RS YUP-612/00A patent/RS50029B/sr unknown
- 1999-04-26 KR KR1020007011944A patent/KR100571534B1/ko not_active Expired - Fee Related
- 1999-04-26 PT PT99947036T patent/PT1073639E/pt unknown
-
2000
- 2000-08-30 IL IL138160A patent/IL138160A/en not_active IP Right Cessation
- 2000-08-31 IS IS5615A patent/IS2082B/is unknown
- 2000-09-01 ZA ZA200004601A patent/ZA200004601B/en unknown
- 2000-10-19 NO NO20005254A patent/NO315606B1/no not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |