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GB2360285B - Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites - Google Patents

Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites

Info

Publication number
GB2360285B
GB2360285B GB0111280A GB0111280A GB2360285B GB 2360285 B GB2360285 B GB 2360285B GB 0111280 A GB0111280 A GB 0111280A GB 0111280 A GB0111280 A GB 0111280A GB 2360285 B GB2360285 B GB 2360285B
Authority
GB
United Kingdom
Prior art keywords
zinc finger
sites
finger proteins
targeting
bind
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB0111280A
Other versions
GB2360285A (en
GB0111280D0 (en
Inventor
Stephen P Eisenberg
Casey Christopher Case
Iii George Norbert Cox
Andrew Jamieson
Edward J Rebar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sangamo Therapeutics Inc
Original Assignee
Sangamo Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/229,007 external-priority patent/US6453242B1/en
Application filed by Sangamo Biosciences Inc filed Critical Sangamo Biosciences Inc
Publication of GB0111280D0 publication Critical patent/GB0111280D0/en
Publication of GB2360285A publication Critical patent/GB2360285A/en
Application granted granted Critical
Publication of GB2360285B publication Critical patent/GB2360285B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/20—Protein or domain folding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GB0111280A 1999-01-12 2000-01-12 Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites Expired - Lifetime GB2360285B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/229,007 US6453242B1 (en) 1999-01-12 1999-01-12 Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
GB0000651A GB2348425B (en) 1999-01-12 2000-01-12 Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to binds to preselected sites

Publications (3)

Publication Number Publication Date
GB0111280D0 GB0111280D0 (en) 2001-06-27
GB2360285A GB2360285A (en) 2001-09-19
GB2360285B true GB2360285B (en) 2002-02-27

Family

ID=26243385

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0111280A Expired - Lifetime GB2360285B (en) 1999-01-12 2000-01-12 Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites

Country Status (1)

Country Link
GB (1) GB2360285B (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042474A2 (en) * 1998-02-20 1999-08-26 Genome Dynamics, Inc. Method for designing dna-binding proteins of the zinc-finger class

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042474A2 (en) * 1998-02-20 1999-08-26 Genome Dynamics, Inc. Method for designing dna-binding proteins of the zinc-finger class

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Febs Letters Vol. 274 (1,2) 1990. Kothekar V et.al. pages 217-222 *
The EMBO J. Vol. 11 (12) 1992. Jacobs G H pages 4507-4517 *

Also Published As

Publication number Publication date
GB2360285A (en) 2001-09-19
GB0111280D0 (en) 2001-06-27

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Expiry date: 20200111