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IL135639A0 - Novel methylenebisphosphonic acid derivatives - Google Patents

Novel methylenebisphosphonic acid derivatives

Info

Publication number
IL135639A0
IL135639A0 IL13563998A IL13563998A IL135639A0 IL 135639 A0 IL135639 A0 IL 135639A0 IL 13563998 A IL13563998 A IL 13563998A IL 13563998 A IL13563998 A IL 13563998A IL 135639 A0 IL135639 A0 IL 135639A0
Authority
IL
Israel
Prior art keywords
acid derivatives
methylenebisphosphonic acid
novel methylenebisphosphonic
novel
derivatives
Prior art date
Application number
IL13563998A
Other languages
English (en)
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of IL135639A0 publication Critical patent/IL135639A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4071Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/409Compounds containing the structure P(=X)-X-acyl, P(=X) -X-heteroatom, P(=X)-X-CN (X = O, S, Se)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4071Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/409Compounds containing the structure P(=X)-X-acyl, P(=X) -X-heteroatom, P(=X)-X-CN (X = O, S, Se)
    • C07F9/4093Compounds containing the structure P(=X)-X-C(=X)- (X = O, S, Se)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13563998A 1997-10-20 1998-10-20 Novel methylenebisphosphonic acid derivatives IL135639A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI974001A FI104901B (fi) 1997-10-20 1997-10-20 Uudet metyleenibisfosfonihappojohdannaiset
PCT/FI1998/000814 WO1999020634A1 (en) 1997-10-20 1998-10-20 Novel methylenebisphosphonic acid derivatives

Publications (1)

Publication Number Publication Date
IL135639A0 true IL135639A0 (en) 2001-05-20

Family

ID=8549759

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13563998A IL135639A0 (en) 1997-10-20 1998-10-20 Novel methylenebisphosphonic acid derivatives

Country Status (19)

Country Link
US (1) US6326363B1 (et)
EP (1) EP1032578A1 (et)
JP (1) JP2001520232A (et)
KR (1) KR20010031269A (et)
CN (1) CN1147497C (et)
AU (1) AU740355B2 (et)
BG (1) BG104452A (et)
BR (1) BR9813102A (et)
CA (1) CA2306080A1 (et)
EE (1) EE04061B1 (et)
FI (1) FI104901B (et)
HU (1) HUP0004386A3 (et)
IL (1) IL135639A0 (et)
NO (1) NO20002006L (et)
NZ (1) NZ504390A (et)
PL (1) PL340055A1 (et)
RU (1) RU2205833C2 (et)
TR (1) TR200001055T2 (et)
WO (1) WO1999020634A1 (et)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO313180B1 (no) * 2000-07-04 2002-08-26 Anticancer Therapeutic Inv Sa Bensökende alfapartikkel emitterende radiofarmasöytika
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
US8288545B2 (en) * 2006-07-21 2012-10-16 Glsynthesis Inc. Reactive pyrophosphoric and bisphosphonic acid derivatives and methods of their use
CA2747188C (en) 2008-11-20 2017-06-13 Glsynthesis Inc. Antithrombotic diadenosine tetraphosphates and related analogs
CN107011380A (zh) * 2016-01-28 2017-08-04 臧伟 一种二膦酸衍生物及含二膦酸衍生物的组合物治疗骨折的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4447256A (en) 1977-07-20 1984-05-08 Nissan Chemical Industries, Ltd. N-(Unsubstituted or substituted pyridyl)aminomethylene-diphosphonic acids, herbicidal compositions containing same, their use for herbicides, and process for preparing same
DE2758580A1 (de) 1977-12-29 1979-07-05 Hoechst Ag Verfahren zur herstellung von phosphin- und phosphonsaeure-anhydriden
HU199151B (en) 1987-03-10 1990-01-29 Yamanouchi Pharma Co Ltd Process for producing bis-phosphonic acid derivatives
US4933472A (en) 1988-04-08 1990-06-12 Yamanouchi Pharmaceutical Co., Ltd. Substituted aminomethylenebis(phosphonic acid) derivatives
EP0356866A3 (en) 1988-08-29 1991-03-27 E.R. SQUIBB & SONS, INC. Phosphorus-containing squalene synthetase inhibitors and method
FI83421C (fi) * 1989-06-21 1991-07-10 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt anvaendbara metylenbisfosfonsyraderivat.
EP0416689B1 (en) * 1989-09-06 1995-11-29 Merck & Co. Inc. Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors
FI89365C (fi) * 1990-12-20 1993-09-27 Leiras Oy Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat
FI89364C (fi) * 1990-12-20 1993-09-27 Leiras Oy Foerfarande foer framstaellning av nya, farmakologiskt anvaendbara metylenbisfosfonsyraderivat
FI89366C (fi) 1990-12-20 1993-09-27 Leiras Oy Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat
PL297372A1 (en) 1991-04-06 1993-09-06 Fisons Plc Atp analogs
TW237386B (et) 1992-04-15 1995-01-01 Ciba Geigy
CN1042430C (zh) * 1993-02-10 1999-03-10 英国阿斯特拉药品有限公司 N-烷基-2-取代的atp类似物、其制备方法和用途
US5462932A (en) 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations

Also Published As

Publication number Publication date
NO20002006D0 (no) 2000-04-17
BG104452A (en) 2000-12-29
CA2306080A1 (en) 1999-04-29
CN1147497C (zh) 2004-04-28
FI104901B (fi) 2000-04-28
JP2001520232A (ja) 2001-10-30
US6326363B1 (en) 2001-12-04
NZ504390A (en) 2001-10-26
CN1276793A (zh) 2000-12-13
HUP0004386A3 (en) 2002-08-28
RU2205833C2 (ru) 2003-06-10
PL340055A1 (en) 2001-01-15
KR20010031269A (ko) 2001-04-16
EP1032578A1 (en) 2000-09-06
HUP0004386A2 (hu) 2001-04-28
FI974001A0 (fi) 1997-10-20
NO20002006L (no) 2000-06-15
EE04061B1 (et) 2003-06-16
FI974001L (fi) 1999-04-21
WO1999020634A1 (en) 1999-04-29
AU9543798A (en) 1999-05-10
AU740355B2 (en) 2001-11-01
EE200000239A (et) 2001-08-15
BR9813102A (pt) 2000-08-22
TR200001055T2 (tr) 2000-09-21

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