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IL134469A0 - Tetrahydrofuran phosphate- and hydroxy esters as prodrugs for the corrersponding antifungal agent - Google Patents

Tetrahydrofuran phosphate- and hydroxy esters as prodrugs for the corrersponding antifungal agent

Info

Publication number
IL134469A0
IL134469A0 IL13446998A IL13446998A IL134469A0 IL 134469 A0 IL134469 A0 IL 134469A0 IL 13446998 A IL13446998 A IL 13446998A IL 13446998 A IL13446998 A IL 13446998A IL 134469 A0 IL134469 A0 IL 134469A0
Authority
IL
Israel
Prior art keywords
corrersponding
prodrugs
tetrahydrofuran
phosphate
antifungal agent
Prior art date
Application number
IL13446998A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL134469A0 publication Critical patent/IL134469A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • C07F9/6518Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13446998A 1997-09-25 1998-09-22 Tetrahydrofuran phosphate- and hydroxy esters as prodrugs for the corrersponding antifungal agent IL134469A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93782797A 1997-09-25 1997-09-25
PCT/US1998/018508 WO1999015522A1 (en) 1997-09-25 1998-09-22 Tetrahydrofuran phosphate- and hydroxy esters, as prodrugs for the corresponding antifungal agent

Publications (1)

Publication Number Publication Date
IL134469A0 true IL134469A0 (en) 2001-04-30

Family

ID=25470461

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13446998A IL134469A0 (en) 1997-09-25 1998-09-22 Tetrahydrofuran phosphate- and hydroxy esters as prodrugs for the corrersponding antifungal agent

Country Status (25)

Country Link
EP (1) EP1027349B1 (pt)
JP (1) JP3473949B2 (pt)
KR (1) KR20010024297A (pt)
CN (1) CN1125066C (pt)
AR (1) AR015458A1 (pt)
AT (1) ATE286502T1 (pt)
AU (1) AU1698199A (pt)
BR (1) BR9812671A (pt)
CA (1) CA2304624C (pt)
CO (1) CO5011088A1 (pt)
DE (1) DE69828524T2 (pt)
ES (1) ES2232974T3 (pt)
HU (1) HUP0004616A3 (pt)
ID (1) ID28294A (pt)
IL (1) IL134469A0 (pt)
MY (1) MY133775A (pt)
NO (1) NO20001557D0 (pt)
NZ (1) NZ502709A (pt)
PE (1) PE120799A1 (pt)
PL (1) PL339488A1 (pt)
PT (1) PT1027349E (pt)
SK (1) SK3912000A3 (pt)
TR (1) TR200000753T2 (pt)
WO (1) WO1999015522A1 (pt)
ZA (1) ZA988688B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000030655A1 (en) 1998-11-20 2000-06-02 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
RU2585760C2 (ru) * 2010-05-19 2016-06-10 Сандоз Аг Способ получения хиральных триазолонов
CN111138421A (zh) * 2019-12-26 2020-05-12 上海英诺富成生物科技有限公司 抗真菌水溶性化合物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693626A (en) * 1993-12-21 1997-12-02 Schering Corporation Tetrahydrofuran antifungals
TW377349B (en) * 1993-12-21 1999-12-21 Schering Corp Tetrahydrofuran antifungals

Also Published As

Publication number Publication date
NO20001557L (no) 2000-03-24
CA2304624C (en) 2007-06-19
CN1125066C (zh) 2003-10-22
JP2001517665A (ja) 2001-10-09
JP3473949B2 (ja) 2003-12-08
EP1027349B1 (en) 2005-01-05
NO20001557D0 (no) 2000-03-24
PE120799A1 (es) 1999-12-01
CN1271356A (zh) 2000-10-25
AU1698199A (en) 1999-04-12
BR9812671A (pt) 2000-08-22
AR015458A1 (es) 2001-05-02
ZA988688B (en) 1999-03-23
ATE286502T1 (de) 2005-01-15
DE69828524D1 (de) 2005-02-10
CA2304624A1 (en) 1999-04-01
PT1027349E (pt) 2005-05-31
TR200000753T2 (tr) 2001-01-22
PL339488A1 (en) 2000-12-18
KR20010024297A (ko) 2001-03-26
HUP0004616A2 (hu) 2002-03-28
HUP0004616A3 (en) 2002-04-29
DE69828524T2 (de) 2005-12-29
HK1025960A1 (en) 2000-12-01
SK3912000A3 (en) 2000-08-14
EP1027349A1 (en) 2000-08-16
NZ502709A (en) 2001-11-30
CO5011088A1 (es) 2001-02-28
ID28294A (id) 2001-05-10
MY133775A (en) 2007-11-30
WO1999015522A1 (en) 1999-04-01
ES2232974T3 (es) 2005-06-01

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