IL122102A - Peptides and compounds that bind to a thrombopoietin receptor, pharmaceutical compositions comprising them and their use as medicaments - Google Patents
Peptides and compounds that bind to a thrombopoietin receptor, pharmaceutical compositions comprising them and their use as medicamentsInfo
- Publication number
- IL122102A IL122102A IL12210296A IL12210296A IL122102A IL 122102 A IL122102 A IL 122102A IL 12210296 A IL12210296 A IL 12210296A IL 12210296 A IL12210296 A IL 12210296A IL 122102 A IL122102 A IL 122102A
- Authority
- IL
- Israel
- Prior art keywords
- group
- peptide
- compound
- amino acids
- peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48530195A | 1995-06-07 | 1995-06-07 | |
| US47812895A | 1995-06-07 | 1995-06-07 | |
| PCT/US1996/009623 WO1996040750A1 (en) | 1995-06-07 | 1996-06-07 | Peptides and compounds that bind to a thrombopoietin receptor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL122102A0 IL122102A0 (en) | 1998-04-05 |
| IL122102A true IL122102A (en) | 2002-07-25 |
Family
ID=27045796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12210296A IL122102A (en) | 1995-06-07 | 1996-06-07 | Peptides and compounds that bind to a thrombopoietin receptor, pharmaceutical compositions comprising them and their use as medicaments |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US6083913A (es) |
| EP (4) | EP2055712A1 (es) |
| JP (1) | JP3059218B2 (es) |
| KR (1) | KR100436680B1 (es) |
| CN (2) | CN1966520B (es) |
| AR (1) | AR003431A1 (es) |
| AT (1) | ATE390439T1 (es) |
| BR (1) | BR9608587A (es) |
| CA (2) | CA2223449C (es) |
| CZ (1) | CZ291749B6 (es) |
| DE (1) | DE69637473T2 (es) |
| DK (1) | DK0885242T3 (es) |
| EA (1) | EA001220B1 (es) |
| ES (1) | ES2303338T3 (es) |
| HU (1) | HU227678B1 (es) |
| IL (1) | IL122102A (es) |
| MX (1) | MX9709315A (es) |
| NO (2) | NO317737B1 (es) |
| NZ (1) | NZ310778A (es) |
| PE (1) | PE7898A1 (es) |
| PL (1) | PL188795B1 (es) |
| PT (1) | PT885242E (es) |
| TR (1) | TR199701526T1 (es) |
| TW (1) | TW518341B (es) |
| WO (1) | WO1996040750A1 (es) |
| ZA (1) | ZA964814B (es) |
Families Citing this family (84)
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| US5869451A (en) | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| CN1966520B (zh) * | 1995-06-07 | 2012-07-11 | 葛兰素集团有限公司 | 结合血小板生成素受体的肽和化合物 |
| US6251864B1 (en) | 1995-06-07 | 2001-06-26 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| US6172210B1 (en) * | 1996-04-02 | 2001-01-09 | Blood Center Research Foundation | DNA encoding phospholipid scramblase |
| US7091311B2 (en) | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
| US6593456B1 (en) * | 1996-11-06 | 2003-07-15 | The Regents Of The University Of California | Tumor necrosis factor receptor releasing enzyme |
| US6930084B1 (en) | 1996-11-06 | 2005-08-16 | The Regents Of The University Of California | Treating arthritis with TNF receptor releasing enzyme |
| US6420518B1 (en) | 1997-04-04 | 2002-07-16 | Genetech, Inc. | Insulin-like growth factor agonist molecules |
| US6121416A (en) | 1997-04-04 | 2000-09-19 | Genentech, Inc. | Insulin-like growth factor agonist molecules |
| WO1999052877A1 (en) * | 1998-04-14 | 1999-10-21 | Smithkline Beecham Corporation | Receptor ligands |
| US7153655B2 (en) | 1998-06-16 | 2006-12-26 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence |
| DK2319928T3 (da) | 1998-10-23 | 2013-06-24 | Kirin Amgen Inc | Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| IL143866A0 (en) | 1999-01-06 | 2002-04-21 | Genentech Inc | Insulin-like growth factor (igf) i mutant variants |
| US6911314B2 (en) | 1999-05-14 | 2005-06-28 | The Regents Of The University Of California | Screening for drugs that affect TNF receptor releasing enzyme |
| EP1216037A2 (en) | 1999-09-21 | 2002-06-26 | Emory University | Methods and compositions for treating platelet-related disorders using mpl pathway inhibitory agents |
| TWI284639B (en) | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
| WO2001087323A2 (en) | 2000-05-16 | 2001-11-22 | Genentech, Inc. | Method for treating cartilage disorders |
| CY2010012I2 (el) | 2000-05-25 | 2020-05-29 | Novartis Ag | Μιμητικα θρομβοποιητινης |
| JP3966816B2 (ja) * | 2000-05-30 | 2007-08-29 | 中外製薬株式会社 | トロンボポエチン様活性を有する化合物 |
| US7396917B2 (en) | 2000-12-05 | 2008-07-08 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
| ES2258558T3 (es) | 2000-12-05 | 2006-09-01 | Alexion Pharmaceuticals, Inc. | Anticuerpos diseñados racionalmente. |
| US6958213B2 (en) | 2000-12-12 | 2005-10-25 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function |
| JP4145654B2 (ja) | 2001-01-26 | 2008-09-03 | 塩野義製薬株式会社 | トロンボポエチン受容体アゴニスト作用を有する環状化合物 |
| WO2002078612A2 (en) * | 2001-04-02 | 2002-10-10 | Euro-Celtique S.A. | Thrombopoietin (tpo) synthebody for stimulation of platelet production |
| US7332474B2 (en) * | 2001-10-11 | 2008-02-19 | Amgen Inc. | Peptides and related compounds having thrombopoietic activity |
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| AR040083A1 (es) | 2002-05-22 | 2005-03-16 | Smithkline Beecham Corp | Compuesto bis-(monoetanolamina) del acido 3'-[(2z)-[1-(3,4-dimetilfenil) -1,5-dihidro-3-metil-5-oxo-4h-pirazol-4-iliden] hidrazino] -2'-hidroxi-[1,1'-bifenil]-3-carboxilico, procedimiento para prepararlo, composicion farmaceutica que lo comprende, procedimiento para preparar dicha composicion farmac |
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| US7736909B2 (en) * | 2003-01-09 | 2010-06-15 | Board Of Regents, The University Of Texas System | Methods and compositions comprising capture agents |
| CA2525497A1 (en) | 2003-05-12 | 2004-11-25 | Affymax, Inc. | Peptides that bind to the erythropoietin receptor |
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1996
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