IL126860A0 - Inhibitors of the production of s-cd23 and secretion of tnf - Google Patents

Inhibitors of the production of s-cd23 and secretion of tnf

Info

Publication number: IL126860A0
Authority: IL; Israel
Prior art keywords: tnf; secretion; inhibitors; production
Prior art date: 1996-05-10

Application number

IL12686097A

Other languages

English (en)

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-10

Filing date

1997-05-06

Publication date

1999-09-22

1997-05-06 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

1999-09-22 Publication of IL126860A0 publication Critical patent/IL126860A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Quinoline Compounds (AREA)
Furan Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL12686097A 1996-05-10 1997-05-06 Inhibitors of the production of s-cd23 and secretion of tnf IL126860A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9609794.4A GB9609794D0 (en)	1996-05-10	1996-05-10	Novel compounds
PCT/EP1997/002433 WO1997043249A1 (en)	1996-05-10	1997-05-06	INHIBITORS OF THE PRODUCTION OF s-CD23 AND THE SECRETION OF TNF

Publications (1)

Publication Number	Publication Date
IL126860A0 true IL126860A0 (en)	1999-09-22

Family

ID=10793494

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12686097A IL126860A0 (en)	1996-05-10	1997-05-06	Inhibitors of the production of s-cd23 and secretion of tnf

Country Status (21)

Country	Link
US (1)	US6235753B1 (xx)
EP (1)	EP0918747B1 (xx)
JP (1)	JP2000510473A (xx)
KR (1)	KR20000010892A (xx)
AR (1)	AR007060A1 (xx)
AT (1)	ATE246673T1 (xx)
AU (1)	AU2897397A (xx)
BR (1)	BR9709450A (xx)
CA (1)	CA2253590A1 (xx)
CO (1)	CO4990945A1 (xx)
CZ (1)	CZ363198A3 (xx)
DE (1)	DE69723984T2 (xx)
ES (1)	ES2205218T3 (xx)
GB (1)	GB9609794D0 (xx)
IL (1)	IL126860A0 (xx)
NO (1)	NO985214L (xx)
NZ (1)	NZ332628A (xx)
PL (1)	PL329855A1 (xx)
TR (1)	TR199802271T2 (xx)
WO (1)	WO1997043249A1 (xx)
ZA (1)	ZA973964B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20020082200A1 (en) *	1994-07-13	2002-06-27	Smithkline Beecham P.1.C.	Use of inhibitors of human S-CD23
US6548084B2 (en)	1995-07-20	2003-04-15	Smithkline Beecham Plc	Controlled release compositions
AUPO721997A0 (en) *	1997-06-06	1997-07-03	Queensland Institute Of Medical Research, The	Anticancer compounds
ATE286892T1 (de)	1997-11-12	2005-01-15	Darwin Discovery Ltd	Hydroxam- und carbonsäurederivate mit mmp- und tnf-hemmender aktivität
GB9813451D0 (en) *	1998-06-22	1998-08-19	Smithkline Beecham Plc	Novel compounds
GB9922825D0 (en) *	1999-09-25	1999-11-24	Smithkline Beecham Biolog	Medical use
AU783504C (en)	1999-11-23	2006-08-03	Methylgene Inc.	Inhibitors of histone deacetylase
GB9930754D0 (en) *	1999-12-29	2000-02-16	Smithkline Beecham Plc	Novel compounds
US7652036B2 (en) *	2003-02-25	2010-01-26	Topotarget Uk Limited	Carbamic acid compounds comprising a bicyclic heteroaryl group as HDAC inhibitors
GB0818907D0 (en) *	2008-10-15	2008-11-19	Isis Innovation	Histone lysine demethylase inhibitors
UY32660A (es)	2009-05-28	2010-12-31	Novartis Ag	Derivados aminobutricos sustituidos como inhibidores de neprilisina
ME01923B (me) *	2009-05-28	2015-05-20	Novartis Ag	Supstituisani derivati aminopropionske kiseline kao inhibitori neprilizina
WO2011068853A2 (en)	2009-12-01	2011-06-09	Boston Medical Center Corporation	TREATMENT OF IgE-MEDIATED DISEASE
LT2956464T (lt)	2013-02-14	2018-07-10	Novartis Ag	Pakeisti bisfenilbutanoinės fosfonrūgšties dariniai, kaip nep (neutralios endopeptidazės) inhibitoriai
CA2900226A1 (en)	2013-02-14	2014-08-21	Novartis Ag	Substituted bisphenyl butanoic acid derivatives as nep inhibitors with improved in vivo efficacy
MX2017006413A (es) *	2014-11-19	2017-09-12	Idorsia Pharmaceuticals Ltd	Derivados de benzotiazol antibacterianos.
WO2020070239A1 (en)	2018-10-04	2020-04-09	INSERM (Institut National de la Santé et de la Recherche Médicale)	Egfr inhibitors for treating keratodermas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9215665D0 (en)	1992-07-23	1992-09-09	British Bio Technology	Compounds
ES2144819T3 (es) *	1994-01-20	2000-06-16	British Biotech Pharm	L-terc-leucina-2-piridilamida.
GB9414157D0 (en) *	1994-07-13	1994-08-31	Smithkline Beecham Plc	Medical use
US5562917A (en)	1994-12-23	1996-10-08	Pentech Pharmaceuticals, Inc.	Transdermal administration of apomorphine
DE19506492C2 (de)	1995-02-24	2003-05-08	Focke & Co	Einrichtung zum Speichern von Zigaretten oder dergleichen
US5570079A (en)	1995-04-24	1996-10-29	Dockery; Devan	Home security system for detecting an intrusion into a monitored area by an infrared detector

1996
- 1996-05-10 GB GBGB9609794.4A patent/GB9609794D0/en active Pending
1997
- 1997-05-06 CZ CZ983631A patent/CZ363198A3/cs unknown
- 1997-05-06 NZ NZ332628A patent/NZ332628A/en unknown
- 1997-05-06 BR BR9709450A patent/BR9709450A/pt not_active Application Discontinuation
- 1997-05-06 IL IL12686097A patent/IL126860A0/xx unknown
- 1997-05-06 AT AT97923064T patent/ATE246673T1/de not_active IP Right Cessation
- 1997-05-06 WO PCT/EP1997/002433 patent/WO1997043249A1/en not_active Ceased
- 1997-05-06 DE DE69723984T patent/DE69723984T2/de not_active Expired - Fee Related
- 1997-05-06 ES ES97923064T patent/ES2205218T3/es not_active Expired - Lifetime
- 1997-05-06 TR TR1998/02271T patent/TR199802271T2/xx unknown
- 1997-05-06 CA CA002253590A patent/CA2253590A1/en not_active Abandoned
- 1997-05-06 JP JP09540514A patent/JP2000510473A/ja not_active Ceased
- 1997-05-06 PL PL97329855A patent/PL329855A1/xx unknown
- 1997-05-06 US US09/180,547 patent/US6235753B1/en not_active Expired - Fee Related
- 1997-05-06 KR KR1019980709039A patent/KR20000010892A/ko not_active Withdrawn
- 1997-05-06 EP EP97923064A patent/EP0918747B1/en not_active Expired - Lifetime
- 1997-05-06 AU AU28973/97A patent/AU2897397A/en not_active Abandoned
- 1997-05-08 AR ARP970101926A patent/AR007060A1/es not_active Application Discontinuation
- 1997-05-08 ZA ZA973964A patent/ZA973964B/xx unknown
- 1997-05-09 CO CO97025078A patent/CO4990945A1/es unknown
1998
- 1998-11-09 NO NO985214A patent/NO985214L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0918747A1 (en)	1999-06-02
DE69723984T2 (de)	2004-06-09
NO985214L (no)	1998-12-01
CZ363198A3 (cs)	1999-06-16
WO1997043249A1 (en)	1997-11-20
BR9709450A (pt)	1999-08-10
NO985214D0 (no)	1998-11-09
ZA973964B (en)	1998-11-09
CA2253590A1 (en)	1997-11-20
JP2000510473A (ja)	2000-08-15
ES2205218T3 (es)	2004-05-01
KR20000010892A (ko)	2000-02-25
TR199802271T2 (xx)	2000-08-21
US6235753B1 (en)	2001-05-22
PL329855A1 (en)	1999-04-12
NZ332628A (en)	2000-06-23
ATE246673T1 (de)	2003-08-15
GB9609794D0 (en)	1996-07-17
CO4990945A1 (es)	2000-12-26
AR007060A1 (es)	1999-10-13
AU2897397A (en)	1997-12-05
EP0918747B1 (en)	2003-08-06
DE69723984D1 (de)	2003-09-11

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