IL118518A - Preparations for the treatment of internal parasites containing the history of abramectin and cyclic precipitated peptides - Google Patents

Preparations for the treatment of internal parasites containing the history of abramectin and cyclic precipitated peptides

Info

Publication number: IL118518A
Authority: IL; Israel
Prior art keywords: spp; ivermectin; praziquantel; blb; bla
Prior art date: 1995-06-02

Application number

IL11851896A

Other languages

English (en)

Hebrew (he)

Other versions

IL118518A0 (en

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-02

Filing date

1996-05-31

Publication date

1998-12-27

1996-05-31 Application filed by Bayer Ag filed Critical Bayer Ag

1996-09-12 Publication of IL118518A0 publication Critical patent/IL118518A0/xx

1998-12-27 Publication of IL118518A publication Critical patent/IL118518A/en

Links

239000000203 mixture Substances 0.000 title claims abstract description 39
108010002156 Depsipeptides Proteins 0.000 title claims abstract description 26
RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical class C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 title claims description 9
150000002596 lactones Chemical class 0.000 claims abstract description 24
229960005362 epsiprantel Drugs 0.000 claims abstract description 14
LGUDKOQUWIHXOV-UHFFFAOYSA-N epsiprantel Chemical compound C1C(C2=CC=CC=C2CCC2)N2C(=O)CN1C(=O)C1CCCCC1 LGUDKOQUWIHXOV-UHFFFAOYSA-N 0.000 claims abstract description 14
FSVJFNAIGNNGKK-UHFFFAOYSA-N 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one Chemical compound C1C(C2=CC=CC=C2CC2)N2C(=O)CN1C(=O)C1CCCCC1 FSVJFNAIGNNGKK-UHFFFAOYSA-N 0.000 claims description 28
229960002957 praziquantel Drugs 0.000 claims description 28
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FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 claims description 16
BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical class OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 claims description 9
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OHRURASPPZQGQM-GCCNXGTGSA-N romidepsin Chemical compound O1C(=O)[C@H](C(C)C)NC(=O)C(=C/C)/NC(=O)[C@H]2CSSCC\C=C\[C@@H]1CC(=O)N[C@H](C(C)C)C(=O)N2 OHRURASPPZQGQM-GCCNXGTGSA-N 0.000 description 4
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QLFZZSKTJWDQOS-YDBLARSUSA-N doramectin Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C3CCCCC3)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C QLFZZSKTJWDQOS-YDBLARSUSA-N 0.000 description 3
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244000052769 pathogen Species 0.000 description 1
230000004796 pathophysiological change Effects 0.000 description 1
239000008188 pellet Substances 0.000 description 1
230000000149 penetrating effect Effects 0.000 description 1
229960005323 phenoxyethanol Drugs 0.000 description 1
235000021317 phosphate Nutrition 0.000 description 1
150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
229920000151 polyglycol Polymers 0.000 description 1
239000010695 polyglycol Substances 0.000 description 1
229920001451 polypropylene glycol Polymers 0.000 description 1
RWPGFSMJFRPDDP-UHFFFAOYSA-L potassium metabisulfite Chemical compound [K+].[K+].[O-]S(=O)S([O-])(=O)=O RWPGFSMJFRPDDP-UHFFFAOYSA-L 0.000 description 1
235000010263 potassium metabisulphite Nutrition 0.000 description 1
239000004297 potassium metabisulphite Substances 0.000 description 1
230000003389 potentiating effect Effects 0.000 description 1
235000008476 powdered milk Nutrition 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
ZPWFUIUNWDIYCJ-UHFFFAOYSA-N propan-2-yl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC(C)C ZPWFUIUNWDIYCJ-UHFFFAOYSA-N 0.000 description 1
229960000996 pyrantel pamoate Drugs 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
238000012552 review Methods 0.000 description 1
235000003441 saturated fatty acids Nutrition 0.000 description 1
150000004671 saturated fatty acids Chemical class 0.000 description 1
235000002639 sodium chloride Nutrition 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
JNYAEWCLZODPBN-CTQIIAAMSA-N sorbitan Polymers OCC(O)C1OCC(O)[C@@H]1O JNYAEWCLZODPBN-CTQIIAAMSA-N 0.000 description 1
239000001587 sorbitan monostearate Substances 0.000 description 1
235000011076 sorbitan monostearate Nutrition 0.000 description 1
229940035048 sorbitan monostearate Drugs 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
238000005507 spraying Methods 0.000 description 1
230000007480 spreading Effects 0.000 description 1
238000003892 spreading Methods 0.000 description 1
239000008117 stearic acid Substances 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
235000000346 sugar Nutrition 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
239000000454 talc Substances 0.000 description 1
229910052623 talc Inorganic materials 0.000 description 1
235000012222 talc Nutrition 0.000 description 1
125000004213 tert-butoxy group Chemical group [H]C([H])([H])C(O*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 1
229940124597 therapeutic agent Drugs 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
235000010384 tocopherol Nutrition 0.000 description 1
229960001295 tocopherol Drugs 0.000 description 1
229930003799 tocopherol Natural products 0.000 description 1
239000011732 tocopherol Substances 0.000 description 1
238000006257 total synthesis reaction Methods 0.000 description 1
230000001988 toxicity Effects 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
150000004670 unsaturated fatty acids Chemical class 0.000 description 1
235000021122 unsaturated fatty acids Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
239000007762 w/o emulsion Substances 0.000 description 1
239000001993 wax Substances 0.000 description 1
210000002268 wool Anatomy 0.000 description 1
GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)

IL11851896A 1995-06-02 1996-05-31 Preparations for the treatment of internal parasites containing the history of abramectin and cyclic precipitated peptides IL118518A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19520275A DE19520275A1 (de)	1995-06-02	1995-06-02	Endoparasitizide Mittel

Publications (2)

Publication Number	Publication Date
IL118518A0 IL118518A0 (en)	1996-09-12
IL118518A true IL118518A (en)	1998-12-27

Family

ID=7763518

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11851896A IL118518A (en)	1995-06-02	1996-05-31	Preparations for the treatment of internal parasites containing the history of abramectin and cyclic precipitated peptides

Country Status (25)

Country	Link
US (1)	US6159932A (fr)
EP (1)	EP0828506B1 (fr)
JP (1)	JP4104653B2 (fr)
KR (1)	KR100434388B1 (fr)
CN (1)	CN1142790C (fr)
AR (1)	AR005640A1 (fr)
AT (1)	ATE213645T1 (fr)
AU (1)	AU703048B2 (fr)
BR (1)	BR9608961A (fr)
CA (1)	CA2222680C (fr)
CZ (1)	CZ287290B6 (fr)
DE (2)	DE19520275A1 (fr)
DK (1)	DK0828506T3 (fr)
ES (1)	ES2173284T3 (fr)
HU (1)	HU224961B1 (fr)
IL (1)	IL118518A (fr)
NO (1)	NO316608B1 (fr)
NZ (1)	NZ309073A (fr)
PL (1)	PL184848B1 (fr)
PT (1)	PT828506E (fr)
SK (1)	SK283884B6 (fr)
TR (1)	TR199701484T1 (fr)
TW (1)	TW469133B (fr)
WO (1)	WO1996038165A2 (fr)
ZA (1)	ZA964473B (fr)

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DE19545044A1 (de) *	1995-12-02	1997-06-05	Bayer Ag	Endoparasitizide Mittel
WO1998006407A1 (fr) *	1996-07-30	1998-02-19	Ashmont Holdings Limited	Formulations anti-helminthes
DE19654079A1 (de) *	1996-12-23	1998-06-25	Bayer Ag	Endo-ekto-parasitizide Mittel
GB9825402D0 (en) †	1998-11-19	1999-01-13	Pfizer Ltd	Antiparasitic formulations
DE19921887A1 (de) *	1999-05-12	2000-11-16	Bayer Ag	Endoparasitizide Mittel
DE19962147A1 (de) *	1999-12-22	2001-06-28	Bayer Ag	Schädlingsbekämpfungsmittel / PF 1022-221
DE19962145A1 (de) *	1999-12-22	2001-06-28	Bayer Ag	Schädlingsbekämpfungsmittel/Depsipeptide
DE10008128A1 (de) *	2000-02-22	2001-08-23	Bayer Ag	Endoparasitizide Mittel
DK1197215T3 (da) *	2000-10-10	2006-07-10	Wyeth Corp	Anthelmintiske sammensætninger
US6893652B2 (en) *	2001-08-27	2005-05-17	Wyeth	Endoparasiticidal gel composition
MXPA04003854A (es) *	2001-10-25	2005-02-17	Sankyo Lifetech Company Ltd	Composicion antihelmintica.
US7001889B2 (en) *	2002-06-21	2006-02-21	Merial Limited	Anthelmintic oral homogeneous veterinary pastes
ITMI20031015A1 (it) *	2003-05-20	2004-11-21	Naxospharma S R L	Poli-(amminopirrolcarbossammidi) per uso nella profilassi e nel trattamento delle endoparassitosi animali e loro composizioni con ciclodestrine.
DE10358525A1 (de) *	2003-12-13	2005-07-07	Bayer Healthcare Ag	Endoparasitizide Mittel zur topischen Applikation
DE10359798A1 (de) *	2003-12-19	2005-07-21	Bayer Healthcare Ag	Cyclohexadepsipeptide zur Bekämpfung von Endoparasiten und ein Verfahren zu ihrer Herstellung
CA2561348A1 (fr) *	2004-04-07	2005-10-27	Intervet International B.V.	Composition efficace d'un benzimidazole, d'une avermectine et de praziquantel et procedes d'utilisation associes
US20060147485A1 (en) *	2005-01-04	2006-07-06	Morten Pedersen	Oil-in-water formulation of avermectins
WO2006069580A1 (fr) *	2004-12-30	2006-07-06	Cheminova A/S	Formulation huile dans eau d'avermectines
DE102005011779A1 (de) *	2005-03-11	2006-09-14	Bayer Healthcare Ag	Endoparasitizide Mittel
US20080027011A1 (en) *	2005-12-20	2008-01-31	Hassan Nached	Homogeneous paste and gel formulations
WO2012028556A1 (fr) *	2010-08-31	2012-03-08	Bayer Animal Health Gmbh	Lactones macrocycliques et leur utilisation et leurs combinaisons avec d'autres substances actives
AU2011315555B2 (en)	2010-10-12	2016-03-10	Elanco Animal Health Gmbh	Non-starch based soft chewables
CA2811931C (fr) *	2010-10-20	2015-06-16	Galderma S.A.	Procede de traitement d'une infection par le virus de l'herpes utilisant un compose lactone macrocyclique
KR20140136005A (ko)	2012-03-13	2014-11-27	바이엘 뉴질랜드 리미티드	지속성 조성물
AU2013361760B2 (en)	2012-12-19	2018-07-05	Elanco Animal Health Gmbh	Tablets with improved acceptance and good storage stability
KR20170132330A (ko) *	2015-04-02	2017-12-01	메리얼 인코포레이티드	구충성 조합 및 그의 사용 방법
BR112017024773A2 (pt)	2015-05-20	2018-11-06	Merial, Inc.	compostos depsipeptídeos anti-helmínticos
WO2017116702A1 (fr)	2015-12-28	2017-07-06	Merial, Inc.	Composés depsipeptidiques anthelminthiques
CN107318861A (zh) *	2016-04-28	2017-11-07	江苏龙灯化学有限公司	一种杀虫组合物
BR112019009977A2 (pt)	2016-11-16	2019-08-27	Boehringer Ingelheim Animal Health Usa Inc	compostos depsipeptídicos anti-helmínticos
ES3016807T3 (en) *	2017-03-17	2025-05-09	Telluris Biotech India Private Ltd	A synergistic composition of a nematicide
US10857151B1 (en) *	2020-02-21	2020-12-08	Villya LLC	Treatment of female genital schistosomiasis
US20220047506A1 (en)	2020-08-12	2022-02-17	Villya LLC	Praziquantel Formulations
CA3191671A1 (fr)	2020-09-04	2022-03-10	Elanco Us Inc.	Formulations palatables
WO2024158694A1 (fr)	2023-01-23	2024-08-02	Villya LLC	Compositions et méthodes pour améliorer la solubilité d'agents thérapeutiques du dysfonctionnement érectile

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SE434277B (sv) *	1976-04-19	1984-07-16	Merck & Co Inc	Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
JPS57139012A (en) *	1981-02-23	1982-08-27	Sankyo Co Ltd	Anthelmintic composition
ZA842571B (en) *	1983-04-07	1985-11-27	Merck & Co Inc	Novel synergistic antiparasitic combinations
NO176766C (no) *	1989-02-07	1995-05-24	Meiji Seika Kaisha	Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet
GB9024924D0 (en) *	1990-11-16	1991-01-02	Beecham Group Plc	Novel compositions
NZ247278A (en) *	1991-02-12	1995-03-28	Ancare Distributors	Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
JPH0570366A (ja) *	1991-03-08	1993-03-23	Meiji Seika Kaisha Ltd	薬用組成物
AU669883B2 (en) *	1992-03-17	1996-06-27	Astellas Pharma Inc.	Depsipeptide derivative, production thereof and use thereof
DE4317458A1 (de) *	1992-06-11	1993-12-16	Bayer Ag	Verwendung von cyclischen Depsipeptiden mit 18 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 18 Ringatomen und Verfahren zu ihrer Herstellung
CN1073560C (zh) *	1993-02-19	2001-10-24	明治制果株式会社	环缩酚酸肽pf1022衍生物
BG61064B1 (bg) *	1993-08-12	1996-10-31	Илия Илиев	Лекарствено средство за обезпаразитяване на животни
DE4400464A1 (de) *	1994-01-11	1995-07-13	Bayer Ag	Endoparasitizide Mittel
DE4401389A1 (de) *	1994-01-19	1995-07-20	Bayer Ag	Verwendung von cyclischen Depsipeptiden mit 12 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 12 Ringatomen und Verfahren zu ihrer Herstellung

1995
- 1995-06-02 DE DE19520275A patent/DE19520275A1/de not_active Withdrawn
1996
- 1996-05-10 TW TW085105513A patent/TW469133B/zh not_active IP Right Cessation
- 1996-05-20 DE DE59608798T patent/DE59608798D1/de not_active Expired - Lifetime
- 1996-05-20 AT AT96916137T patent/ATE213645T1/de active
- 1996-05-20 EP EP96916137A patent/EP0828506B1/fr not_active Expired - Lifetime
- 1996-05-20 HU HU9900346A patent/HU224961B1/hu unknown
- 1996-05-20 TR TR97/01484T patent/TR199701484T1/xx unknown
- 1996-05-20 CA CA002222680A patent/CA2222680C/fr not_active Expired - Lifetime
- 1996-05-20 WO PCT/EP1996/002170 patent/WO1996038165A2/fr not_active Ceased
- 1996-05-20 DK DK96916137T patent/DK0828506T3/da active
- 1996-05-20 NZ NZ309073A patent/NZ309073A/xx not_active IP Right Cessation
- 1996-05-20 US US08/952,356 patent/US6159932A/en not_active Expired - Lifetime
- 1996-05-20 ES ES96916137T patent/ES2173284T3/es not_active Expired - Lifetime
- 1996-05-20 PT PT96916137T patent/PT828506E/pt unknown
- 1996-05-20 SK SK1599-97A patent/SK283884B6/sk not_active IP Right Cessation
- 1996-05-20 CZ CZ19973825A patent/CZ287290B6/cs not_active IP Right Cessation
- 1996-05-20 JP JP53614696A patent/JP4104653B2/ja not_active Expired - Lifetime
- 1996-05-20 BR BR9608961A patent/BR9608961A/pt active IP Right Grant
- 1996-05-20 AU AU59004/96A patent/AU703048B2/en not_active Expired
- 1996-05-20 KR KR1019970708573A patent/KR100434388B1/ko not_active Expired - Lifetime
- 1996-05-20 PL PL96323595A patent/PL184848B1/pl unknown
- 1996-05-20 CN CNB961956615A patent/CN1142790C/zh not_active Expired - Lifetime
- 1996-05-31 ZA ZA9604473A patent/ZA964473B/xx unknown
- 1996-05-31 AR ARP960102860A patent/AR005640A1/es not_active Application Discontinuation
- 1996-05-31 IL IL11851896A patent/IL118518A/en not_active IP Right Cessation
1997
- 1997-12-01 NO NO19975516A patent/NO316608B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0828506T3 (da)	2002-06-10
ES2173284T3 (es)	2002-10-16
JPH11506438A (ja)	1999-06-08
HU224961B1 (en)	2006-04-28
SK283884B6 (sk)	2004-04-06
EP0828506B1 (fr)	2002-02-27
CA2222680C (fr)	2007-11-13
KR19990022094A (ko)	1999-03-25
US6159932A (en)	2000-12-12
DE19520275A1 (de)	1996-12-05
AU5900496A (en)	1996-12-18
WO1996038165A3 (fr)	1997-01-09
BR9608961A (pt)	1999-06-29
ATE213645T1 (de)	2002-03-15
NO975516D0 (no)	1997-12-01
EP0828506A2 (fr)	1998-03-18
CZ382597A3 (cs)	1998-03-18
NO975516L (no)	1998-01-06
HUP9900346A2 (hu)	1999-06-28
ZA964473B (en)	1997-01-29
NO316608B1 (no)	2004-03-08
SK159997A3 (en)	1998-07-08
JP4104653B2 (ja)	2008-06-18
DE59608798D1 (de)	2002-04-04
AU703048B2 (en)	1999-03-11
IL118518A0 (en)	1996-09-12
PT828506E (pt)	2002-08-30
TW469133B (en)	2001-12-21
PL323595A1 (en)	1998-04-14
KR100434388B1 (ko)	2004-08-25
CA2222680A1 (fr)	1996-12-05
CN1191489A (zh)	1998-08-26
MX9709245A (es)	1998-03-31
CN1142790C (zh)	2004-03-24
TR199701484T1 (xx)	1998-03-21
AR005640A1 (es)	1999-07-14
NZ309073A (en)	1998-12-23
CZ287290B6 (en)	2000-10-11
HUP9900346A3 (en)	2000-04-28
PL184848B1 (pl)	2002-12-31
WO1996038165A2 (fr)	1996-12-05

Publication	Publication Date	Title
CA2222680C (fr)	2007-11-13	Agents endoparasiticides
HU218569B (hu)	2000-10-28	Eljárás ciklusos depszipeptidek szulfonilezésére, az így előállított új vegyületek és parazitaellenes szerkénti alkalmazásuk
EP0662326B1 (fr)	2001-11-28	Agents antiparasiticides contenant du praziquantel et de l'epsiprantel
US5712295A (en)	1998-01-27	Agonists and antagonists of the nicotinic acetylcholine receptors of insects to control endoparasites
MXPA96006179A (en)	1998-01-01	Agonists and antagonists of the receptors of the nicotinic acid acetilcoline of insects for the control of endoparasi
AU2002226415B2 (en)	2007-03-22	Crystal modification of a cyclic depsipeptide having improved strength
IL150988A (en)	2011-06-30	Preparations against internal parasites
HUP0102476A2 (hu)	2001-10-28	Szubsztituált ciklooktadepszipeptidek
MXPA97009245A (en)	1998-10-15	Endoperasitician agents
MXPA00011972A (en)	2001-09-07	Substituted cyclooctadepsipeptides

Legal Events

Date	Code	Title
1999-06-20	FF	Patent granted
2000-02-17	KB	Patent renewed
2002-07-25	KB	Patent renewed
2006-08-01	KB	Patent renewed
2010-11-30	KB	Patent renewed
2014-05-28	KB	Patent renewed
2016-12-29	EXP	Patent expired