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IL105965A - Phosphinyloxy propanaminium inner salt derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

Phosphinyloxy propanaminium inner salt derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL105965A
IL105965A IL105965A IL10596593A IL105965A IL 105965 A IL105965 A IL 105965A IL 105965 A IL105965 A IL 105965A IL 10596593 A IL10596593 A IL 10596593A IL 105965 A IL105965 A IL 105965A
Authority
IL
Israel
Prior art keywords
straight
independently
alkylene
alkyl
branched chain
Prior art date
Application number
IL105965A
Other languages
English (en)
Other versions
IL105965A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL105965A0 publication Critical patent/IL105965A0/xx
Publication of IL105965A publication Critical patent/IL105965A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
    • C07F9/165—Esters of thiophosphoric acids
    • C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/113—Esters of phosphoric acids with unsaturated acyclic alcohols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL105965A 1992-06-11 1993-06-09 Phosphinyloxy propanaminium inner salt derivatives, their preparation and pharmaceutical compositions containing them IL105965A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89721092A 1992-06-11 1992-06-11

Publications (2)

Publication Number Publication Date
IL105965A0 IL105965A0 (en) 1993-10-20
IL105965A true IL105965A (en) 1997-03-18

Family

ID=25407534

Family Applications (1)

Application Number Title Priority Date Filing Date
IL105965A IL105965A (en) 1992-06-11 1993-06-09 Phosphinyloxy propanaminium inner salt derivatives, their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
EP (1) EP0574355B1 (xx)
JP (1) JPH0673077A (xx)
KR (1) KR940005647A (xx)
CN (1) CN1039326C (xx)
AT (1) ATE156828T1 (xx)
AU (1) AU667537B2 (xx)
CA (1) CA2098133A1 (xx)
CZ (1) CZ108393A3 (xx)
DE (1) DE69313029T2 (xx)
DK (1) DK0574355T3 (xx)
ES (1) ES2105194T3 (xx)
FI (1) FI932662L (xx)
GR (1) GR3024684T3 (xx)
HU (2) HUT65327A (xx)
IL (1) IL105965A (xx)
MY (1) MY109005A (xx)
NO (1) NO932096L (xx)
NZ (1) NZ247840A (xx)
SG (1) SG42983A1 (xx)
SK (1) SK58893A3 (xx)
ZA (1) ZA934157B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1299266B1 (it) * 1998-05-15 2000-02-29 Sigma Tau Ind Farmaceuti Inibitori reversibili della carnitina palmitoil trasferasi
WO2004074298A1 (ja) * 2003-02-18 2004-09-02 Tokai University ホスホリルコリン基を有する化合物、その重合体ならびにその製造方法
WO2008015081A1 (en) 2006-08-02 2008-02-07 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Derivatives of 4-trimethylammonium-3-aminobutyrate and 4-trimethylphosphonium-3-aminobutyrate as cpt-inhibitors
CA3152868A1 (en) 2019-08-30 2021-03-04 Institute Of Zoology, Chinese Academy Of Sciences Composition used for combating metabolic diseases and uses of composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0348859A1 (en) * 1988-07-01 1990-01-03 MAGIS FARMACEUTICI S.p.A. 1,2-di-O-acyl glycero(DI)phosphate of L-carnitine and its derivatives, a process for their preparation and pharmaceutical formulations which contain them
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
IT1230141B (it) * 1989-05-03 1991-10-14 Fidia Spa Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale.
IT1230142B (it) * 1989-05-03 1991-10-14 Fidia Spa Derivati della carnitina, processo per la loro preparazione e impiego in terapia umana

Also Published As

Publication number Publication date
NZ247840A (en) 1995-04-27
NO932096D0 (no) 1993-06-09
DK0574355T3 (da) 1998-01-26
CA2098133A1 (en) 1993-12-12
CZ108393A3 (en) 1995-02-15
MY109005A (en) 1996-11-30
FI932662A7 (fi) 1993-12-12
IL105965A0 (en) 1993-10-20
HU9301587D0 (en) 1993-09-28
ZA934157B (en) 1994-09-05
CN1039326C (zh) 1998-07-29
FI932662L (fi) 1993-12-12
FI932662A0 (fi) 1993-06-10
ES2105194T3 (es) 1997-10-16
EP0574355B1 (en) 1997-08-13
KR940005647A (ko) 1994-03-22
SK58893A3 (en) 1994-06-08
DE69313029D1 (de) 1997-09-18
CN1086217A (zh) 1994-05-04
DE69313029T2 (de) 1998-01-29
GR3024684T3 (en) 1997-12-31
NO932096L (no) 1993-12-13
HU211489A9 (en) 1995-11-28
SG42983A1 (en) 1997-10-17
AU4011593A (en) 1993-12-16
AU667537B2 (en) 1996-03-28
JPH0673077A (ja) 1994-03-15
HUT65327A (en) 1994-05-02
ATE156828T1 (de) 1997-08-15
EP0574355A1 (en) 1993-12-15

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Legal Events

Date Code Title Description
FF Patent granted
HC Change of name of proprietor(s)
KB Patent renewed
RH Patent void